LOCUS       XM_021526599            6619 bp    mRNA    linear   VRT 01-DEC-2025
DEFINITION  PREDICTED: Lonchura striata ATPase copper transporting beta
            (ATP7B), mRNA.
ACCESSION   XM_021526599
VERSION     XM_021526599.3
DBLINK      BioProject: PRJNA1295486
KEYWORDS    RefSeq.
SOURCE      Lonchura striata (white-rumped munia)
  ORGANISM  Lonchura striata
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
            Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves;
            Passeriformes; Passeroidea; Estrildidae; Estrildinae; Lonchura.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_134604) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Dec 1, 2025 this sequence version replaced XM_021526599.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_046129695.1-RS_2025_08
            Annotation Pipeline         :: NCBI Eukaryotic Genome Annotation
                                           Pipeline (EGAP)
            Annotation Software Version :: 10.5
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/21/2025
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6619
                     /organism="Lonchura striata"
                     /mol_type="mRNA"
                     /isolate="bLonStr1"
                     /db_xref="taxon:40157"
                     /chromosome="2"
                     /sex="male"
                     /tissue_type="blood"
                     /dev_stage="adult"
                     /geo_loc_name="USA: Millbrook, New York"
                     /lat_lon="41.7677 N 73.7508 W"
                     /collection_date="2023-10-11"
                     /collected_by="Matthew Biegler"
     gene            1..6619
                     /gene="ATP7B"
                     /note="ATPase copper transporting beta; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 14 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 1 sample
                     with support for all annotated introns"
                     /db_xref="GeneID:110468571"
     CDS             270..4862
                     /gene="ATP7B"
                     /codon_start=1
                     /product="copper-transporting ATPase 2"
                     /protein_id="XP_021382274.2"
                     /db_xref="GeneID:110468571"
                     /translation="

MERKLDNKMKRELSCLATLNDRNISLVSIRKQQAACDVPELLIIGEKSKTASPVKASSNLQKEEKVLRSYSTGMTEVNTDERQALSNIDSPPGCELKPTMKHKFAFDNMGYEETSETMSSPPSQEHTMVVNIVGMTCQSCVQSIEGRICKVKGILRIKVSLEQNNAVIKYLQLEISPEQICQEILDMGFDASIAEEKLTTATVNLPSLKEAVAKLRVEGMTCQSCVTNIEGKIRKLHGVAKIKVSLDNQEAIIAYHPYIIQPEDLKRHISDLGYDCTIKSKSAPLKLGALDLQRLQNANPKETSASLESDGLDLLVPEMSSTATATVQIEGMHCKSCVRNIEGNISDLPGIKCIKVSLENKCAVVQYSPDLITLSALQQAIESLPPGNFKVSLLSGSEANKAASPSGAFTYNVVRQPPQGTTHTAVIKIDGMTCNSCVKSIEGAISQRQGVQNVSVSLAGSTGTIHYDPAVTSGEELRAAIEDMGFDASVLTDTATGEKRCQPDASKAAVQPQAPEPPRQGNVSNALPDSPHPDGSNQLSGAREEKCVLQITGMTCASCVSTIERNLQKEDGIVSVLVALMAGKAEIKYKPELIQPLEIAQLIQNLGFEATIMENKAETEGQVELLITGMTCASCVHNIESKLMRTNGIFSASVALATSKAHIQFDPEIIGPRDIIKVIKEIGFHASVAKRAPNAHNLSHKKEIQQWRKSFLFSLVFGIPVVVIMIYMQIPSGEDHGSKVLEQNLIPGLSILNLLFFILCTFVQFLGGWYFYVQAYKSLRHKTANMDVLIVLATTIAYLYSCVILIVAIIEKAEKSPVTFFDTPPMLFVFIALGRWLEHIAKGKTSEALAKLMSLQATEATVVTLGPGHSIVREEQVPVELVQRGDIIKVVPGGKFPVDGKVIEGNSMADESLITGEPMPVIKKPGSTVIAGSINAHGSLLVNATHVGNDTTLAQIVKLVEEAQMSKAPIQQLADKFSGYFVPFIIIISTVTLIVWITIGFVNFDVIKKYFPNQSKNISKAEIILRFAFQTSITVLSIACPCSLGLATPTAVMVGTGVAAQNGILIKGGKPLEMAHQIKTVMFDKTGTITYGVPKVMRVLLMGDTAVLPLKKVLAVVGTAEASSEHPLGMAVTKYCKEELGTERLGYCTDFQAVPGCGISCKVGGVEAILGTGEEGPNELDANRSGDSSAPLGDNRVITLLESQGPSASQKYSVLIGNREWMQRNGLNIANDVNDAMTNHEMKGQTAILVAIDGVLCGMIAIADTVKQEAALAVHTLQSMGIDVVLITGDNRKTAKAIATQVGIKKVFAEVLPSHKVAKVQELQNGKKKVAMVGDGVNDSPALARADVGIAIGTGTDVAIEAADVVLIRNDLLDVVASIHLSKRTVRRIRINLILALIYNLLGIPIAAGVFMPVGLVLQPWMGSAAMAASSVSVLLSSLQLKCYKKPDTESYEAQAQGRMKPLTPSQISVHIGMDDRRRDSSKPSPWDQTSQVSLSSLASDRLPRRNGFIQEEGGKWSLLINGADEEQYI"

     misc_feature    654..845
                     /gene="ATP7B"
                     /note="Heavy-metal-associated domain (HMA) is a conserved
                     domain of approximately 30 amino acid residues found in a
                     number of proteins that transport or detoxify heavy
                     metals, for example, the CPx-type heavy metal ATPases and
                     copper chaperones. HMA domain...; Region: HMA; cd00371"
                     /db_xref="CDD:238219"
     misc_feature    order(672..680,687..689)
                     /gene="ATP7B"
                     /note="metal-binding site [ion binding]"
                     /db_xref="CDD:238219"
     misc_feature    909..1100
                     /gene="ATP7B"
                     /note="Heavy-metal-associated domain (HMA) is a conserved
                     domain of approximately 30 amino acid residues found in a
                     number of proteins that transport or detoxify heavy
                     metals, for example, the CPx-type heavy metal ATPases and
                     copper chaperones. HMA domain...; Region: HMA; cd00371"
                     /db_xref="CDD:238219"
     misc_feature    order(927..935,942..944)
                     /gene="ATP7B"
                     /note="metal-binding site [ion binding]"
                     /db_xref="CDD:238219"
     misc_feature    1233..1421
                     /gene="ATP7B"
                     /note="Copper chaperone CopZ [Inorganic ion transport and
                     metabolism]; Region: CopZ; COG2608"
                     /db_xref="CDD:442020"
     misc_feature    1539..1745
                     /gene="ATP7B"
                     /note="Copper chaperone CopZ [Inorganic ion transport and
                     metabolism]; Region: CopZ; COG2608"
                     /db_xref="CDD:442020"
     misc_feature    1911..2102
                     /gene="ATP7B"
                     /note="Heavy-metal-associated domain (HMA) is a conserved
                     domain of approximately 30 amino acid residues found in a
                     number of proteins that transport or detoxify heavy
                     metals, for example, the CPx-type heavy metal ATPases and
                     copper chaperones. HMA domain...; Region: HMA; cd00371"
                     /db_xref="CDD:238219"
     misc_feature    order(1929..1937,1944..1946)
                     /gene="ATP7B"
                     /note="metal-binding site [ion binding]"
                     /db_xref="CDD:238219"
     misc_feature    2139..2330
                     /gene="ATP7B"
                     /note="Heavy-metal-associated domain (HMA) is a conserved
                     domain of approximately 30 amino acid residues found in a
                     number of proteins that transport or detoxify heavy
                     metals, for example, the CPx-type heavy metal ATPases and
                     copper chaperones. HMA domain...; Region: HMA; cd00371"
                     /db_xref="CDD:238219"
     misc_feature    order(2157..2165,2172..2174)
                     /gene="ATP7B"
                     /note="metal-binding site [ion binding]"
                     /db_xref="CDD:238219"
     misc_feature    2394..4535
                     /gene="ATP7B"
                     /note="P-type heavy metal-transporting ATPase, similar to
                     human copper-transporting ATPases, ATP7A and ATP7B;
                     Region: P-type_ATPase_Cu-like; cd02094"
                     /db_xref="CDD:319783"
     misc_feature    order(3387..3389,3393..3395,4464..4466)
                     /gene="ATP7B"
                     /note="putative Cu binding site [ion binding]; other site"
                     /db_xref="CDD:319783"
     misc_feature    order(3519..3527,3729..3731,3915..3923,4011..4013,
                     4131..4139,4197..4199,4206..4208,4215..4217,4272..4274,
                     4281..4283)
                     /gene="ATP7B"
                     /note="putative ATP binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:319783"
     polyA_site      6619
                     /gene="ATP7B"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      

agctgggaaagcacgagggatgccaattggtgggaaacatttaaactggcagggagagcaggtagctgagtgcagcaagcagcctacataaggatcgcaggttgcatctggtatttcctgatgaatgcctaataagcccatggattagacgggcagaactcttcaagctgctgtaaatgtagttgaaagaagtgtggcttgtaggacaccaaataactgctctcgtgaaaccttttttggcattgcaatatttaaagaccagaaaaataatggagagaaaactggacaataaaatgaaaagggaactgtcctgcttagctactttaaacgacagaaacatatccttggtgtctattcgtaaacagcaggcagcttgtgatgtgcctgaactactgattattggtgaaaagtccaagacggcatctccggtaaaagcaagcagtaacttgcagaaagaagagaaagttttgcggagttactccacgggaatgacagaagtcaatacagatgaaaggcaggctttgtctaacattgattctcctcctggttgtgagctgaagcctacaatgaaacataaatttgctttcgacaacatgggctatgaggagacctctgaaaccatgtcctctccaccttcccaagagcatactatggtagtcaacattgtgggaatgacttgccaatcatgtgtgcagtcaatagaaggccgaatttgcaaggtgaagggcattttgagaattaaagtctcccttgaacagaacaatgctgttatcaagtatctgcagttggaaataagccctgaacagatttgccaggaaattctggatatgggctttgatgccagcatagcagaagagaagctgacaacagcaactgtaaatttgccaagcttgaaagaagcggtagctaagcttcgggtagaaggcatgacatgccagtcctgtgtcaccaacattgaaggaaagattaggaaactgcatggtgtagcaaaaatcaaggtgtcacttgataaccaagaagcaattattgcttaccatccttacatcattcagcctgaggacctcaagagacacatcagtgacctggggtatgactgcaccattaaaagtaaatcagcccctttgaagctgggtgcccttgatctccagcgcttgcagaatgcaaaccctaaggagacatctgcaagtctcgagagtgatgggctggatctgctggtccctgagatgagtagcacagcaacagcgactgtacagatagagggcatgcactgcaagtcctgtgtcagaaacatcgaaggaaatatatcagatcttcctggcataaaatgtattaaagtgtctttggagaataaatgtgctgtggtacagtatagcccagatttaatcaccctgtcagctctgcagcaagccattgaatcccttccacctgggaactttaaagttagcctccttagtggttcagaagcaaataaagcagcatctccctcaggtgctttcacatacaatgtcgtcagacagccaccacaaggcacgacacatacagctgttattaagattgatggcatgacctgcaattcttgtgtgaagtccatcgaaggggccatatcacagaggcagggagtgcagaacgtgtcagtttcccttgctggcagtactgggaccatacactatgatccagctgtcacaagtggagaagagttaagagctgccatagaagacatgggatttgatgcctctgtgctgacagatactgccactggagaaaagaggtgccagcctgatgccagcaaagctgctgtgcagcctcaagctccagagcctcctcgccaaggcaatgtctcgaatgctcttccagacagtcctcaccctgatgggtcaaaccagctcagtggagccagagaagaaaagtgtgttttacagatcacaggcatgacctgtgcatcgtgtgtgtctaccattgaaagaaatttgcagaaagaagatggaattgtttcagtattggtagcactgatggcaggtaaagcagagataaaatacaagccagaactcatacaacctcttgaaatagcacagctgatccagaatttgggttttgaagctaccattatggaaaataaagcagaaacagaagggcaagtggagcttcttattacagggatgacttgtgcttcttgtgttcacaatattgaatccaaactcatgagaacaaatggcatattctctgcctcagttgcacttgcaactagcaaagctcacatccagtttgatcctgaaattattggtccacgagatattataaaagtaatcaaggaaattggctttcatgcttctgtggctaaaagagctccaaatgcacataatctgagtcataaaaaggaaatacagcagtggaggaaatctttcttattcagcctagtgtttggtatcccagttgtagtcataatgatttatatgcaaatacccagtggtgaagaccatgggtctaaggtgctggaacagaacctcattcctggattatctattttgaatcttctgttctttatcctgtgcacttttgtccagttccttggtggatggtatttttatgtacaagcttacaagtcactgaggcacaagacagccaatatggacgtgctcatcgtgctggccacgacgattgcttatctgtattcctgcgtcatcctgatagtagcaatcattgaaaaggcagagaaaagccctgtcactttctttgacactcctccgatgttgtttgtgttcattgcgcttggcagatggctggaacacatagccaagggtaagacctctgaagctcttgctaagcttatgtctcttcaagccacggaagccactgtggtgactcttggacctggccactctattgtcagggaggagcaagtacctgtcgaactggttcaaaggggtgatattataaaagttgttcctggtggaaagttcccagtggatggaaaggtcattgaaggcaattctatggcagatgagtctctcattactggggaacctatgccagtcattaaaaagcctgggagcacggtgattgctggttctataaatgcacatggctcacttcttgttaatgcaacgcatgttggtaatgataccactctggcacagattgtgaaattggtggaagaagctcaaatgtcaaaggcacccatccagcaactggcagataaatttagtggatactttgttccatttatcatcatcatttcaactgtgacattgatagtatggatcacaattggttttgtaaattttgatgttattaaaaaatattttcctaatcagagcaaaaacatttcaaaagctgaaataatactgaggtttgcatttcaaacctcaatcactgtgctgagcattgcatgcccttgctccttaggcctggctacccccacagctgtaatggtgggaacaggagtggctgcgcagaatggtattctcatcaaaggtggaaaacccctggaaatggcacatcagatcaagactgtgatgtttgataaaactgggaccatcacctatggagttcctaaagtcatgagagtgcttttgatgggagacacagctgtgctccccctgaagaaggtactggcggttgttggtacagcagaagccagcagtgaacatcctttgggaatggccgtcactaaatactgcaaagaggagcttggcactgagaggctaggatactgcactgacttccaggcagtcccaggctgtggtatcagctgcaaggtcggaggagttgaggccatccttggcacaggtgaggaaggtcccaatgagctggatgctaacaggagtggagacagcagtgctcctctgggagataacagagttatcacgctcttggaatcacaaggtccatcagcttctcagaaatattcggtgctgatcggaaatcgtgagtggatgcaacgcaatggcttgaatattgcaaatgatgtaaatgatgcaatgacaaaccatgaaatgaaaggacagactgccatactagtggctatagatggtgtgttgtgtggaatgatcgcaatagcagacacggtcaagcaggaggcagcccttgctgtgcacacactgcagagcatgggaatagacgtggtgctcataacaggggacaacaggaaaactgcaaaagccattgctactcaggttgggatcaaaaaagtctttgcggaggttcttccttctcacaaagttgcaaaggtccaggagctccaaaatggaaagaagaaggttgcaatggttggtgatggagtcaacgattcccctgcactagccagggccgatgttggaattgcaattggaacgggcactgatgttgccattgaagctgcagatgttgttcttatccgaaatgatttgctggacgtagttgccagtattcacttatccaagagaacagttcgaagaatacgaataaatctcattcttgccttaatttataatctgcttggaatacccatagcggcaggtgtgttcatgcctgttggcctcgtgcttcagccttggatgggatcagctgcaatggcagcttcttctgtgtctgtcctgctgtcttcactgcaactgaaatgttacaagaagccagacacagaaagttacgaagcacaagcccaaggccgcatgaagccactcactccttctcaaatcagtgttcacattggaatggatgataggaggagggattcttccaaaccatctccttgggatcagacaagccaagtgtccctctcttccttggcttcagacaggctgccgagacgcaatggtttcattcaggaggaagggggcaagtggtcattgctcataaatggagcagatgaagaacagtacatctgaagcactggactcttagtacaggggaaaatgttcctcctccccagtcaggggagggactgatttatttcatcaacagcttcagtgttgtaagtgaagtattccttcagcgcataagacaatcgcagctcagctcagtgttgggttgtatggattgtggatatttttcaggtcaccagttatttctagttatagaaataaatctgtgccactataatgaactggcttgtttgcacacagcgtttactgaaataatgtaaagtggtaattttcagactctaaaagagtttctctgtgactctttgctaggagccaaatttcaaaattttcactcttttaaactttattacttcaagaccacatgaagcaagagtattttcagagctggcaaatattaatttgtgtctaaatgaaattagcaatggcataaggaaatctgtggtcagaagttttacacagaatcctaactagacacgccactgtgaggatttaggattcatggcatctcctggcaccaaaaatgctttgctgtttcacctgctacaactctctgaaaggtctttttcaaagattttcacttgctttgagggattgcatccttttgatgcacatttctactgctctctttgattttctgttttgctctatatgagccctttttttcttgcatgagagatcttctatgagttattgttatatttacagatattcctgtttgggacaaactcctttatatcaccagaaaccatttcattccaattgaaatccataaaggcagaacagttcctggtcctagttatccaagaaaccttgctgaaccccagggagctccttagaactgggcagttttctgtctctttcctgtgacagagtgaagaatttatgccagtgtgagcaaaggtggtatttaccttggtatgactgagcagaactagcactggtgtaactccagcatagctgaacagagttgagattattgcataacttaaccccagcttgctgcttgcttaaaatgaagataacaatttaaattataaaggtggaaagatgaccttaaagtgggcttctatttgccatcatattaataaatgacaggacctaaactaagaaaatttgtaatttaaatttctgttttgcattgattttagttcccctctttacttcaatgagaaatcaaagtactggacagctgtttttctgctttaacatctttaccaaagcttgcagtaacttaatctctgtgtatgtcagatccaccccttaacacttcttagagtcaggacagtaggaatcaacagctttggtgctctggatccaattccagagcactgtgttgtccagctgtgggaccctgatgtaagcagagctttatagtcaaatttagaaactgaaagaaatggaaatactttgctaaacaacatgaaataactacttttcattgactgaaatatagagctgtttctaacacaggctcaaaacctgcttctcctaatgtaaaaatgaagaacaagtcagagaggaaaagaattgctcttaaagcattggatgggtcttcctattttctcagcactttccgaaatataattacaaatcagttttaaaactctatataagtagagattaatttcacagcacatacacttttcaaacatgccaaaggtgcatgtccctgtgggaaagtgggtctgaagttttactattctgtattttcttaccagtccttacagtaaaaatatgcctctttttttttttatcaaaca

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