LOCUS       XM_021200287            7325 bp    mRNA    linear   ROD 18-JUN-2019
DEFINITION  PREDICTED: Mus pahari argonaute RISC component 1 (LOC110323159),
            transcript variant X2, mRNA.
ACCESSION   XM_021200287
VERSION     XM_021200287.2
DBLINK      BioProject: PRJNA387191
KEYWORDS    RefSeq.
SOURCE      Mus pahari (shrew mouse)
  ORGANISM  Mus pahari
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Coelomys.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_034595.1) annotated using gene prediction method: Gnomon,
            supported by mRNA evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Jun 18, 2019 this sequence version replaced XM_021200287.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Mus pahari Annotation Release 101
            Annotation Version          :: 101
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.2
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7325
                     /organism="Mus pahari"
                     /mol_type="mRNA"
                     /db_xref="taxon:10093"
                     /chromosome="6"
                     /sex="female"
                     /tissue_type="tail"
     gene            1..7325
                     /gene="LOC110323159"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 11 mRNAs, 37 Proteins, and 99%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 5 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:110323159"
     CDS             256..2829
                     /gene="LOC110323159"
                     /codon_start=1
                     /product="protein argonaute-1 isoform X2"
                     /protein_id="XP_021055946.1"
                     /db_xref="GeneID:110323159"
                     /translation="

MEAGPSGAAAGAYLPPLQQVFQAPRRPGIGTVGKPIKLLANYFEVDIPKIDVYHYEVDIKPDKCPRRVNREVVEYMVQHFKPQIFGDRKPVYDGKKNIYTVTALPIGNERVDFEVTIPGEGKDRIFKVSIKWLAIVSWRMLHEALVSGQIPVPLESVQALDVAMRHLASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQSNGRDPQALAKAVQVHQDTLRTMYFA"

     misc_feature    355..747
                     /gene="LOC110323159"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:406799"
     misc_feature    775..927
                     /gene="LOC110323159"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:400854"
     misc_feature    928..1290
                     /gene="LOC110323159"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(1084..1086,1129..1131,1171..1173,1183..1185,
                     1237..1239,1258..1260,1264..1266)
                     /gene="LOC110323159"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1423..2700
                     /gene="LOC110323159"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1834..1836,1846..1848,1882..1893,1900..1902,
                     1924..1926,1933..1935,1945..1947,1957..1959)
                     /gene="LOC110323159"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(2038..2040,2044..2046,2254..2256,2668..2670)
                     /gene="LOC110323159"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

tcgttcccgtccgccccctgggcccatcggtcgcgcctgcgcactggcagctactcgggcgctagcaggaggagctgctgcaggctccgcggcggcggcaacggaggctgcgggggcgacagcgcgagcggccgggcttcgggggggagccgagcccggcccgggagcccgagcagtgcaagtgcgaggtacctaggcccctcacgctggactcctcagtctcccggccgcctgtcctccgcacgggtatatgggatggaagcgggaccctcgggagcagctgcaggtgcctacctgcctcccctgcagcaggtattccaggcacctcgccggcctggcattggcactgtgggcaaaccaatcaagcttctggccaattactttgaggtggacattcctaagattgacgtttaccattacgaggtggacatcaagccggataagtgtcctcgcagagtcaaccgggaggtggtggaatacatggtccagcatttcaaaccacagatctttggggatcgcaagcctgtgtacgatggaaagaagaacatttacacggtcacagcactgcccattggcaatgagagggttgactttgaggtgacaatccctggggaagggaaggatagaatttttaaggtctccatcaagtggctagccattgtgagctggcgcatgctgcatgaagccttggtcagtggccagatccctgtgcccttggagtctgtgcaagccctggatgtggccatgaggcacctggcatctatgaggtacacccctgtgggccgctccttcttctcaccgcctgagggctactaccacccgctggggggtgggcgcgaggtctggttcggctttcaccagtctgtgcgccctgccatgtggaagatgatgctcaacattgatgtctcagccactgccttctacaaagcacagccagtgattgagttcatgtgtgaggtcctggacatcaggaacatagatgaacaacccaagcccctcacggattcccagcgtgttcggtttaccaaggagataaaaggtctgaaggtggaagtgacccactgtggacagatgaaaaggaaataccgcgtgtgtaatgttacccgccgccctgctagccatcagacgttccccttgcagctggagagtggacagactgtggagtgcactgtggcacagtatttcaagcagaaatataaccttcagctcaagtaccctcacctgccctgcctacaggttgggcaagaacagaagcatacctatttgccccttgaggtctgtaacattgtggctgggcagcggtgcattaagaagctgactgacaaccagacttcaaccatgataaaggctacagctaggtccgccccagacagacaggaggagatcagccgcctgatgaagaatgccagctacaacctggatccctacatccaggaatttggaatcaaagtgaaggatgacatgacggaggtgacaggacgtgtgctgccggcgcccatcttgcagtatggcggccggaaccgggccattgctacacccaaccaaggtgtctgggacatgcgcgggaaacagttctacaatgggattgagatcaaagtctgggccatcgcctgcttcgcaccccagaaacagtgtcgggaagaggtgctcaagaacttcacagaccagcttcggaagatttccaaggatgcagggatgcccatccagggtcagccatgcttctgcaaatacgcacagggggcagacagcgtggagcccatgttccggcatctaaagaacacctactcaggactgcagctcattatcgtcatcctgcccgggaagacaccagtgtatgctgaagtgaaacgtgtcggagatacactcttgggaatggcaacacagtgtgtgcaggtgaagaatgtggtcaagacctcacctcagactctgtccaacctctgcctcaagatcaatgtcaaactcggtggcattaataatatcctagtcccacaccagcgctccgctgtttttcaacagccagtgattttcttgggagcagatgttacacatcccccagctggggatgggaagaaaccatctatcacagcagtggtaggcagtatggatgcacaccccagccgatactgtgccaccgtgcgtgtgcagcgcccacggcaggagatcattgaagacttgtcctatatggtgcgtgagctgctcatccagttctacaagtccacccgtttcaagcccacccgaatcatcttctaccgagatggggtccctgagggccagctgccccagattcttcactatgagctgcttgccattcgagatgcatgcatcaaactggaaaaagactaccagcctgggatcacatatattgtggtgcagaagcgccatcacacccgcctcttttgtgctgacaagaatgagcggattgggaagagtggtaacatcccagcagggaccactgtggacaccaacatcacccacccatttgagttcgacttctatctgtgcagccatgcaggcatccagggtaccagccgaccatcccattattatgtcctttgggatgacaaccgtttcacagcagatgaactccagatcttgacataccagctgtgccacacttatgtacgatgcacacgttctgtctctatcccagcacctgcctactatgctcgcttggtggctttccgggcacgataccacctggtggacaaggaacatgacagtggagaggggagccacatatcggggcaaagcaatgggcgagacccccaggccctggccaaagctgtgcaggttcaccaggatactctacgcaccatgtacttcgcttgaaggcgaacgctgttacctcactggatagaagaagaaagctttccgagccctgggagctgtaccacccaaatccagaggaagcaaggcagagggaggtggggtcggaaggagtataagaggccttgtttctatctacagagggggtataagggtgggaagaggaccagcaagacagactaccagccagaaatcactgatagcaacctcattgtcctccaaccctctccccatcttgtcatattcgacccccttggaccaaaaggggcatcactagtgcccaccatacacacagttgtctcatgtgactcacagtgctaaagactcatgctcaacagcttgctagggtcagctctgcagccctgtggtcaaatgctggtatgtttgggtttgatatattctagatgagaaagtgggtgggaagagggcaggaatttttaggagccttaatcagaaaaggtctagatttgtttaaggaaaaaaaggaaaacagactcagatcaatattttaggatactagatgttttcatgggttcagaatccactttgtaggaagatttgtaatgctgatgatttgggttgctcctcccagctgccaccccgtcccatcattcctctccacattctctaccccatacgcctcttccctgacagacatccagtccctcgtaacacttaaggcactatggcacttagctctgaggtgacatgaccctgtcttccttccgcctgctggtgggtaaccagtgccttcctgtaacggtaatgctgcagaactgcaaccttttgtacctttctctgtgggatggggtgtgggtgggagaggaggtagggagggagggaagaaatagcccaacgccagcaagcctccagccagaatgccagctaattttcatttgaaggaattgacttccataatcattgagcttttaaaaaaagatcaccacctctagatggttaaaatccattgacatttgcactttcagacgcgacaagtctccgagctgctgaggtgactggcccttggcctttcccctgtagcctcctcttttccctggccccaccaccaccctgccaggtctagagttactctcatagtatttctcattcttggcttcttttccccctgatggtaaagtctctagtttcaatatttcttaactggggtgtcttacagcagaagatcgtaaggactaaaataagaaaacaaaaaaactaaatgttatttttataccataacttgagtctattgccaaaatctggaaattccctcccatacttgatgagtctgcatcccagaaacatggagccgtaagagggaactgtggacctgacttatgttctggcctggctaagtagggggtggttttctccccaaggtgtggttcagcctctgtccttcctctgtgcagataaaaccttgttctcgagatggcctctctccatggcgctgtcctgcactcttccctgtaagtgcatcttccccttctggactggactgtcctttaattccctgactaaccaagactctagcccgtcctcggggcaggctggggaattttgctgctcccatttgcttctgtttacacaaatgaaattttcctgtttcccactagggcatgcgagtgggtggcatgggcttttcttttttcacccctctcttgaggttctgggttcagctgtcttgcaggactggaaaagaagtgggttctagctttgtccttgctgaccttgaagcaaggccccctctttccttgactgttcagttttcttcctgcattattgcttgggatagggagtttgaacctccgtgtacaggttccccttctgaggagcctgagcttaggactgacttactctggtggtgaagccatgaaactttagatctagcccaggcttagaggccagctggagaaaggaaggtctgaaccctggcctatggagtcaaaacctttccccaagagcccatgtatagacccagatttgctatgcaaatagtccagattcagaaatggctggctacattgttcagtaacttcccaacaggtagcacaaatactccttatggaaaaagcccaggactgttcagtagttcctcctgtacttcttttctgctggctacagtatggagtgccccatgggcacaggcccagctggagaacagaacggagggctctgggaagaggcagctcactggagagcctacattccttacacaagtgcctaaacagagtgatgccaacactccatctgccctgtccatcgccttcatagacagtctacttcgtgttccatcaccctttgggaagggagctcttcacagacagtgtgctgtcaacttgggtacatttgggggcttggattaagggcagtactccaggagggtccagtcattcaccagcatttgcagatgcccatagggaacaacaggtggctgtcacgactcccagcaacaagtttttgttctctccttttttctttgcctcactctctccagttggattttaagctagaatgaaaagcagtttcggtcctttggtatttatgtgccatccaagaaataaaagcaagagaatgctgggcacgatggcccatgtctgtaattctgttatctcagcactaaggctgaagcagaagattttcaagttcagggtccacctgggctactcagtgaattccaggccagtgtgcactatgtagcaagaccatgtctccaaaaaaaagactgagaaaaatgacttgggtgacacatcttgctgtgattttaaataattctttgagacttaactactgaccatgtgggttcctctcatttaaaggcagtatgcacacattaaaaacagtgttgccgagcctcagcttgtttggatttggtgtaagtggtgcattgtaccgagctctgggaggattccagcctcatcttagacagctctttctcctccccccactccctcccatgcctccaccccacccaactattcggctttccctttcctcttctcgccttccctggcttccttttccttctccctcttccctcagcttgcttgctggctggcctgcctgcctggctgcctgtgtgataatgaattctctgcatggctgcaatgatcccactgttagttggcaaggtcaggcttagctcattgactacagaagaccaaaatcctgtttctcatgcccagtggtgttagccctgggttgcactgtcctcaagcttacactaggtcagagcagcaggcctgtctgacaaaattagtagggtttctggcaggttcagcgcctctccattctatggaggggtttggagaaaaggcagtgaaagagtgttgctttgaattcagtccagtgtgatctattggttgaggtgctattgccagcctgttgggatcagcctggagctactgttactgggaacttatccttggactttgactaaagttgaacaaagtatggaactgctctaaaaatctagttctcaactgcaacataggtcctctgtgactgagcagcaatgctttccaacagttttctttttaaccagaattctatgaatgatgccagggacacagttttcttagctgggccatagaaagtctacaaggctgctaagtgttgtagacctggcatcaggcatcacaaaggaggatggaatttcttccctttcagggtagaagagtcacctcttacctagccaaaaggcagttttgggaattcctgtcaggaggaaaggtttggttttgctttttaatttactgggctttagatggtagttcattatgccttccttgggcagggatcatggcagggatacgcaaggcactctaatactcggccttctaagcagactgggaaagggggattctctggttttctctttctccccatttactaggacttgccttctccctgagccacgagagaggctgggttggtgctctccccttactctgctcctactgacttagaacctctggctgctgtacgatagcccaggaaagggaatggaaagaatgggctcaaaacaataatgtaaggaaggtggtttccttccttaaaaagggaaatcagaaactctccaagaattgtgtaagtaaagacaatgtgtctgaatgcactgagtcctctggtgtcatagcaataaggaaaaatgaattgacttcctgtgcacacagtctaacctgactggtgtatgatgttgcacttagcagccatgtggtgggcatgtgtgactactctgggtttcactttattttctaaactttttattcctctcaagtccagcatggatggggaaatgtccctggagccccgcagctgtgtacttgtttgcatttgtttcccattgagacttgtgtttgtgtcctgctttgagctgtaccctgtcccgtccattgtgaaattatcccagcagttgtaatgtacagttcccttctcaagcaagcaacagcagcacaaccttgtgttttataaagacaacagtggcttttatttctaaa

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