LOCUS       XM_020448890             651 bp    mRNA    linear   INV 13-MAR-2017
DEFINITION  Loa loa PAZ domain-containing protein partial mRNA.
ACCESSION   XM_020448890
VERSION     XM_020448890.1
DBLINK      BioProject: PRJNA60051
            BioSample: SAMN00103043
KEYWORDS    RefSeq.
SOURCE      Loa loa (African eye worm)
  ORGANISM  Loa loa
            Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
            Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Loa.
REFERENCE   1  (bases 1 to 651)
  AUTHORS   Nutman,T.B., Fink,D.L., Russ,C., Young,S., Zeng,Q., Gargeya,S.,
            Alvarado,L., Berlin,A., Chapman,S.B., Chen,Z., Freedman,E.,
            Gellesch,M., Goldberg,J., Griggs,A., Gujja,S., Heilman,E.R.,
            Heiman,D., Howarth,C., Mehta,T., Neiman,D., Pearson,M., Roberts,A.,
            Saif,S., Shea,T., Shenoy,N., Sisk,P., Stolte,C., Sykes,S.,
            White,J., Yandava,C., Haas,B., Henn,M.R., Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform, Broad Institute
            Genome Sequencing Center for Infectious Disease
  TITLE     The Genome Sequence of Loa loa
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 651)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (10-MAR-2017) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (bases 1 to 651)
  AUTHORS   Nutman,T.B., Fink,D.L., Russ,C., Young,S., Zeng,Q., Gargeya,S.,
            Alvarado,L., Berlin,A., Chapman,S.B., Chen,Z., Freedman,E.,
            Gellesch,M., Goldberg,J., Griggs,A., Gujja,S., Heilman,E.R.,
            Heiman,D., Howarth,C., Mehta,T., Neiman,D., Pearson,M., Roberts,A.,
            Saif,S., Shea,T., Shenoy,N., Sisk,P., Stolte,C., Sykes,S.,
            White,J., Yandava,C., Haas,B., Henn,M.R., Nusbaum,C. and Birren,B.
  CONSRTM   The Broad Institute Genome Sequencing Platform, Broad Institute
            Genome Sequencing Center for Infectious Disease
  TITLE     Direct Submission
  JOURNAL   Submitted (11-APR-2012) Broad Institute of MIT and Harvard, 7
            Cambridge Center, Cambridge, MA 02142, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. This record is derived from an annotated genomic
            sequence (NW_018109650).
            COMPLETENESS: incomplete on both ends.
FEATURES             Location/Qualifiers
     source          1..651
                     /organism="Loa loa"
                     /mol_type="mRNA"
                     /db_xref="taxon:7209"
                     /chromosome="Unknown"
     gene            <1..>651
                     /locus_tag="LOAG_15057"
                     /db_xref="GeneID:9952543"
     CDS             1..>651
                     /locus_tag="LOAG_15057"
                     /codon_start=1
                     /product="PAZ domain-containing protein"
                     /protein_id="XP_020300994.1"
                     /db_xref="GeneID:9952543"
                     /translation="

MYPNQFGFGERDTPELEEGKYVAVGAAKGVRIVEGPRGFEGGINAALVIDVKKAAFHVDNQCLLEKVECILRRSRVILMRGIDHLSIAILSKALKGLFVRCNYGKNRAFTIGGVSKENARTSKLVSRTGEMSVEKYFEMKYSVKLKYPTLPLIMERCQTKSNFYPMEVLIVCENQRVSKGQQTPSQVQTMIRACATVPSLRLQQTNTLSQAMKLNSS"

     misc_feature    178..516
                     /locus_tag="LOAG_15057"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(325..327,370..372,397..399,409..411,463..465,
                     484..486,490..492)
                     /locus_tag="LOAG_15057"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
ORIGIN      

atgtatccaaatcagtttggctttggagagagagatacacctgagctagaggaagggaaatatgttgctgtgggtgcagcaaagggtgtaagaattgttgaaggtccccgaggctttgaagggggcatcaatgcagcattggtaatcgatgtgaagaaagcagcattccatgtcgataatcagtgtttgcttgagaaggtggaatgcatccttcgcaggagtagagttatcttgatgcggggtattgatcacctctcaatagctattttaagtaaagctctcaaaggattattcgtgcggtgtaattatggtaagaaccgtgcattcactattggaggtgtttcgaaggaaaatgcgcgtacatcgaagttggtgagtagaactggtgaaatgtcagttgagaagtactttgagatgaagtattctgtgaaactgaagtatccaacgttaccattgattatggaacgttgtcaaacgaaaagcaacttctatccgatggaagtactaattgtatgtgaaaatcagcgggtatccaagggacaacagacaccatctcaagtgcagacgatgattcgagcgtgtgctacagttccatctcttcgattgcagcagacgaatacattgagtcaagcgatgaagcttaatagttct

//