LOCUS       XM_018882683            3219 bp    mRNA    linear   PLN 07-JAN-2024
DEFINITION  Sugiyamaella lignohabitans Nma111p (NMA111), partial mRNA.
ACCESSION   XM_018882683
VERSION     XM_018882683.1
DBLINK      BioProject: PRJNA342695
            BioSample: SAMN04417247
KEYWORDS    RefSeq.
SOURCE      Sugiyamaella lignohabitans
  ORGANISM  Sugiyamaella lignohabitans
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Saccharomycetes; Saccharomycetales; Trichomonascaceae;
            Sugiyamaella.
REFERENCE   1  (bases 1 to 3219)
  AUTHORS   Bellasio,M., Peymann,A., Valli,M., Sipitzky,M., Graf,A., Sauer,M.,
            Marx,H. and Mattanovich,D.
  TITLE     Complete genome sequence and transcriptome regulation of the
            pentose utilising yeast Sugiyamaella lignohabitans
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 3219)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2024) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (bases 1 to 3219)
  AUTHORS   Peymann,A. and Graf,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-FEB-2016) Department of Biotechnology, University of
            Natural Resources and Life Sciences, Muthgasse 18, Vienna, Vienna
            1190, Austria
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. This record is derived from an annotated genomic
            sequence (NC_031672).
            COMPLETENESS: incomplete on both ends.
FEATURES             Location/Qualifiers
     source          1..3219
                     /organism="Sugiyamaella lignohabitans"
                     /mol_type="mRNA"
                     /strain="CBS 10342"
                     /type_material="culture from holotype of Candida
                     lignohabitans"
                     /db_xref="taxon:796027"
                     /chromosome="A"
     gene            <1..>3219
                     /gene="NMA111"
                     /locus_tag="AWJ20_725"
                     /db_xref="GeneID:30037789"
     CDS             1..3219
                     /gene="NMA111"
                     /locus_tag="AWJ20_725"
                     /note="Serine protease and general molecular chaperone;
                     involved in response to heat stress and promotion of
                     apoptosis; may contribute to lipid homeostasis; sequence
                     similarity to the mammalian Omi/HtrA2 family of serine
                     proteases; GO_component: GO:0005634 - nucleus [Evidence
                     IEA,IEA]; GO_component: GO:0005634 - nucleus [Evidence
                     IDA] [PMID 14562095]; GO_component: GO:0005634 - nucleus
                     [Evidence IDA] [PMID 14657274]; GO_function: GO:0003824 -
                     catalytic activity [Evidence IEA]; GO_function: GO:0016787
                     - hydrolase activity [Evidence IEA]; GO_function:
                     GO:0008233 - peptidase activity [Evidence IEA];
                     GO_function: GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]; GO_function: GO:0008236 -
                     serine-type peptidase activity [Evidence IEA];
                     GO_function: GO:0008236 - serine-type peptidase activity
                     [Evidence ISS] [PMID 14534547]; GO_function: GO:0008236 -
                     serine-type peptidase activity [Evidence IDA] [PMID
                     18946088]; GO_process: GO:0006915 - apoptotic process
                     [Evidence IEA]; GO_process: GO:0006915 - apoptotic process
                     [Evidence IMP,ISS] [PMID 14657274]; GO_process: GO:0006915
                     - apoptotic process [Evidence IMP,ISS] [PMID 16470384];
                     GO_process: GO:0006915 - apoptotic process [Evidence IMP]
                     [PMID 16608876]; GO_process: GO:0044255 - cellular lipid
                     metabolic process [Evidence IMP,IPI] [PMID 16470384];
                     GO_process: GO:0034605 - cellular response to heat
                     [Evidence IMP] [PMID 18946088]; GO_process: GO:0030163 -
                     protein catabolic process [Evidence IMP] [PMID 18946088];
                     GO_process: GO:0006508 - proteolysis [Evidence IEA,IEA]"
                     /codon_start=1
                     /product="Nma111p"
                     /protein_id="XP_018734947.1"
                     /db_xref="GeneID:30037789"
                     /translation="

MASPPLRRKSSRLSNIPIKRRTSGIADSSPESSSSSVNSVSKRLRTDPESNATIQTINGLESSSDVIVDGNSSALANDPVVSTSFDVSMDDVNNEQFSNNEESELDSEDESNNVVILDDKKLVKTEVLPPSSTTAAVTSSSTTTAMESVEWQKTTERVVKSVVSVQFASVCSFDTEGAFVSEATGFVVDAEQGIIMTNRHVVGSGPFVGYAVFDNHEECDVKPIYRDPVHDFGFLKFDPKRIKHMKVQALELRPDLARVGCEIRVVGNDAGEKLSILAGFISRLDRNAPDYGDLTYNDFNTEYIQAAASTSGGSSGSPVVNIDGNVVALQAGGSTSASTDFFLPLYRGKRALECIRAGQPVTRGTIQAQFLLKPFDECRRLGLTEEAENLARKSFPDAIGLLVAETILPEGPSDGLIREGDCLISINGEQISRFSRVDAILDESIGKEISVTVQRGGKNITSSILVGDLHAITPDRFVTVNGSIFHNISYQIARLYSIPVRGVYVADAGGSFGPERGDATGWILDELDDQPTPDLDAFIEVMKSIADGKRVSARFRHVTDLHTIRYSIVYIDRHWHKSMSLAVRNDVTGLWDYEELGKPLPAEPVLPQKAKFVDLYLENDQVSKLVRSFVKVAARVGSKIEGYYSSSMTEYGLVIDAEKGYVLVTRYTVPHDLLDIYVTVAESVIVPGKVVFMHPLQNYAIVQYDPSLVDAPIESAKLSSTPLKQGTPVVFVGHNHNLRVVSTKTRVTDISTVVIPLSPEVSPRYRGTNLDSVAVDTPLSGDCGSGVLADEDGTIRALWMSFLGDSTGNGRDRQYRLALDITLMRSVIDQLRAGERPNPRVLDVEVNAIQVVNSRIRGVGEEWIRKVEESNNERHQLFNVIRVAQSAAGSLREGDILLAINGKLVTRVLDLNAAQDADEVEVTLVRNRKEMTVTVPTIATDDLATDRVLSWCGINLHKPHHAVVQQLKKSPSDVYVVYSEPGSPANQYGISSTYFITDVNGEPTPNLDRFLEVVSKIPDNTYVKLRIVTFDNLPCACSIKTNYHYFPTSERVRNAAGKWESFSFEDGVRKLI"

     misc_feature    406..1410
                     /gene="NMA111"
                     /locus_tag="AWJ20_725"
                     /note="Periplasmic serine protease, S1-C subfamily,
                     contain C-terminal PDZ domain [Posttranslational
                     modification, protein turnover, chaperones]; Region: DegQ;
                     COG0265"
                     /db_xref="CDD:223343"
     misc_feature    1411..1641
                     /gene="NMA111"
                     /locus_tag="AWJ20_725"
                     /note="PDZ-like domain; Region: PDZ_1; pfam12812"
                     /db_xref="CDD:372324"
     misc_feature    <1960..2805
                     /gene="NMA111"
                     /locus_tag="AWJ20_725"
                     /note="Periplasmic serine protease, S1-C subfamily,
                     contain C-terminal PDZ domain [Posttranslational
                     modification, protein turnover, chaperones]; Region: DegQ;
                     COG0265"
                     /db_xref="CDD:223343"
     misc_feature    <2662..2805
                     /gene="NMA111"
                     /locus_tag="AWJ20_725"
                     /note="PDZ domain, also called DHR (Dlg homologous region)
                     or GLGF (after a conserved sequence motif). Many PDZ
                     domains bind C-terminal polypeptides, though binding to
                     internal (non-C-terminal) polypeptides and even to lipids
                     has been demonstrated; Region: PDZ; cl00117"
                     /db_xref="CDD:444702"
     misc_feature    2824..3060
                     /gene="NMA111"
                     /locus_tag="AWJ20_725"
                     /note="PDZ domain, also called DHR (Dlg homologous region)
                     or GLGF (after a conserved sequence motif). Many PDZ
                     domains bind C-terminal polypeptides, though binding to
                     internal (non-C-terminal) polypeptides and even to lipids
                     has been demonstrated; Region: PDZ; cl00117"
                     /db_xref="CDD:444702"
ORIGIN      

atggctagtcccccactccgcaggaagtcttcgcgattgtccaatatacccattaaacggagaacctctggaatagctgacagctctccggaatcttcttcttcttctgtcaatagtgtgtccaaaagattgcggactgatcccgagtcaaatgctactatccaaactattaatggactcgaatcgtcttcagatgttatcgtggacggtaactcgtcagcattagcaaatgatccggttgtcagcacgtcgtttgacgtttctatggacgatgtaaataacgaacaattttccaataatgaagagtctgaactggattctgaagatgaaagcaataatgttgtcattctcgacgataaaaaattagtgaaaacagaggttctgcctccttcttcgacaactgccgctgtgacttcctcgtctaccactactgctatggagtctgtggaatggcagaaaactactgaacgagttgttaaaagtgttgtttctgtacagtttgcaagtgtgtgctcgtttgatactgaaggtgcttttgtcagcgaggctactggttttgtagtggatgctgagcagggtattattatgaccaaccgtcatgtggttggatccggcccttttgtgggctacgctgtttttgataaccatgaggagtgtgatgttaagcctatttatagagatccagttcatgattttggatttctcaagttcgacccaaaaagaatcaagcatatgaaagttcaagccttggagctgcgtcctgaccttgccagggtcggttgtgaaattagagttgttggtaatgatgctggtgaaaagttgagtattcttgctggttttattagtagactggatagaaatgctccggattacggagacttgacatacaatgatttcaacaccgagtatatccaggctgctgcatccacttcaggtggatccagtggttcaccagttgtaaatatcgatggaaatgtggtagctttacaagctggtggtagtaccagtgcctcgactgatttctttttgccattgtatagaggtaagagggctcttgagtgcattcgtgctggccaacctgtgactagaggtaccattcaagctcagtttctgctgaaacctttcgatgagtgtcgaagattggggctcactgaagaggctgaaaatctcgctcgtaagagtttcccagatgctattggtttgctggttgctgagactattctgcctgagggtccttcagatggtttgattcgcgaaggtgattgtcttatttcaatcaatggagaacagattagtaggttttctcgagttgatgctattctcgatgaatccattggcaaagaaatctcagttactgttcaaagaggtggtaaaaatatcacctcgtctattttagttggtgatcttcatgctattactcctgacaggtttgtcacagtcaatggatctattttccacaatatctcatatcaaattgctagattatactctattcctgttcgtggagtttatgttgcagatgctggtggttcattcggccctgaacgtggtgatgctacaggctggattcttgacgaactggacgaccagccaacacccgatctcgatgctttcattgaagtgatgaaatctattgctgatggtaagagagtgtcagctagattccgtcatgtcaccgatctccacaccattcggtactcaattgtatatatagaccgacactggcacaagtccatgtcccttgctgttcgtaacgatgtcactggattatgggattacgaagagcttggaaagccacttcccgcagagccagttcttcctcagaaggccaagtttgtggatctttatttagaaaacgaccaagtatcaaaattagtgcgaagttttgtcaaggtcgcagcccgtgtcggttctaagattgaaggttattacagcagttctatgaccgagtatggcctcgttattgatgctgaaaagggttatgttcttgttacgagatacactgttcctcatgatctcctcgatatttacgtgacagttgctgaatctgttattgtccctggtaaggtggttttcatgcatcctcttcaaaattacgctattgttcaatatgatccttcacttgttgatgctcctattgagtcagctaaactcagcagtacccctctgaaacagggtactccagttgtgtttgtcggacacaaccacaaccttcgagttgtttccacgaaaactcgtgtcaccgatatcagtacggtcgtgattcctctttccccagaagtatctcccagataccgaggaaccaatttagactcagtggctgttgacactcctctcagtggagactgtggatcaggcgtgcttgctgatgaggatggtactattcgagctctgtggatgtctttccttggcgacagcactggaaacggccgggaccgtcaataccgtcttgccctggatataactcttatgagaagtgttatcgaccaacttcgtgctggtgaacgccccaaccctcgagttcttgatgtcgaagtcaatgctattcaagtagtgaattcgcgtattcgaggtgtcggtgaggagtggattcgaaaggttgaagaaagcaacaacgagcgtcaccaactgttcaatgttatccgagtggcacaatcagctgctggttcccttcgagaaggtgatattcttcttgctatcaacggaaagctcgtgacccgagttctcgatctcaatgctgcacaggatgccgatgaggtagaagtcaccctcgtaagaaaccgaaaagagatgaccgtcactgttcccacaatcgctactgacgacctcgcgaccgaccgagtgctttcttggtgcggtattaatcttcacaaaccccatcacgctgttgtccagcagttgaagaagtctccatctgacgtgtacgttgtatactccgagcccggatctcctgccaaccaatacggcatctcatcaacctacttcatcaccgacgtcaacggcgagccgaccccgaacctcgacaggttcctggaagtggtgtctaaaatccccgacaacacctacgtcaagctgcgcatcgtgaccttcgacaacctaccatgcgcctgctccattaaaaccaactaccactacttccccacatccgaacgtgtccgcaacgctgccggcaaatgggaatcgttctctttcgaggacggtgtacgtaaattaatttaa

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