LOCUS       XM_018881243            4752 bp    mRNA    linear   PLN 07-JAN-2024
DEFINITION  Sugiyamaella lignohabitans Esp1p (ESP1), partial mRNA.
ACCESSION   XM_018881243
VERSION     XM_018881243.1
DBLINK      BioProject: PRJNA342695
            BioSample: SAMN04417247
KEYWORDS    RefSeq.
SOURCE      Sugiyamaella lignohabitans
  ORGANISM  Sugiyamaella lignohabitans
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Saccharomycetes; Saccharomycetales; Trichomonascaceae;
            Sugiyamaella.
REFERENCE   1  (bases 1 to 4752)
  AUTHORS   Bellasio,M., Peymann,A., Valli,M., Sipitzky,M., Graf,A., Sauer,M.,
            Marx,H. and Mattanovich,D.
  TITLE     Complete genome sequence and transcriptome regulation of the
            pentose utilising yeast Sugiyamaella lignohabitans
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4752)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2024) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (bases 1 to 4752)
  AUTHORS   Peymann,A. and Graf,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-FEB-2016) Department of Biotechnology, University of
            Natural Resources and Life Sciences, Muthgasse 18, Vienna, Vienna
            1190, Austria
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. This record is derived from an annotated genomic
            sequence (NC_031671).
            COMPLETENESS: incomplete on both ends.
FEATURES             Location/Qualifiers
     source          1..4752
                     /organism="Sugiyamaella lignohabitans"
                     /mol_type="mRNA"
                     /strain="CBS 10342"
                     /type_material="culture from holotype of Candida
                     lignohabitans"
                     /db_xref="taxon:796027"
                     /chromosome="C"
     gene            <1..>4752
                     /gene="ESP1"
                     /locus_tag="AWJ20_4184"
                     /db_xref="GeneID:30036288"
     CDS             1..4752
                     /gene="ESP1"
                     /locus_tag="AWJ20_4184"
                     /inference="similar to AA sequence:KEGG_Orthology:K02365"
                     /note="Separase, a caspase-like cysteine protease;
                     promotes sister chromatid separation by mediating
                     dissociation of the cohesin Scc1p from chromatin; inhibits
                     protein phosphatase 2A-Cdc55p to promote mitotic exit;
                     inhibited by Pds1p; relative distribution to the nucleus
                     increases upon DNA replication stress; GO_component:
                     GO:0005737 - cytoplasm [Evidence IEA,IEA]; GO_component:
                     GO:0005737 - cytoplasm [Evidence IDA] [PMID 11149918];
                     GO_component: GO:0005737 - cytoplasm [Evidence IDA] [PMID
                     22842922]; GO_component: GO:0005856 - cytoskeleton
                     [Evidence IEA]; GO_component: GO:0005739 - mitochondrion
                     [Evidence IDA] [PMID 14576278]; GO_component: GO:0005739 -
                     mitochondrion [Evidence IDA] [PMID 16823961];
                     GO_component: GO:0005634 - nucleus [Evidence IEA,IEA,IEA];
                     GO_component: GO:0005634 - nucleus [Evidence IDA] [PMID
                     11149918]; GO_component: GO:0005634 - nucleus [Evidence
                     IDA] [PMID 22842922]; GO_component: GO:0005819 - spindle
                     [Evidence IDA] [PMID 11149918]; GO_component: GO:0005816 -
                     spindle pole body [Evidence IEA]; GO_function: GO:0004197
                     - cysteine-type endopeptidase activity [Evidence IDA]
                     [PMID 11081625]; GO_function: GO:0008234 - cysteine-type
                     peptidase activity [Evidence IEA]; GO_function: GO:0016787
                     - hydrolase activity [Evidence IEA]; GO_function:
                     GO:0008233 - peptidase activity [Evidence IEA,IEA];
                     GO_process: GO:0006915 - apoptotic process [Evidence IMP]
                     [PMID 18321989]; GO_process: GO:0007059 - chromosome
                     segregation [Evidence IEA]; GO_process: GO:0000070 -
                     mitotic sister chromatid segregation [Evidence IMP,IPI]
                     [PMID 9635435]; GO_process: GO:0034048 - negative
                     regulation of protein phosphatase type 2A activity
                     [Evidence IMP,IPI] [PMID 16713564]; GO_process: GO:0006508
                     - proteolysis [Evidence IEA,IEA]; GO_process: GO:0007096 -
                     regulation of exit from mitosis [Evidence IGI,IPI] [PMID
                     12598903]; GO_process: GO:0032888 - regulation of mitotic
                     spindle elongation [Evidence IGI,IMP] [PMID 18430955]"
                     /codon_start=1
                     /product="Esp1p"
                     /protein_id="XP_018733852.1"
                     /db_xref="GeneID:30036288"
                     /translation="

MSISNSASLITSTLLRCSALKIIPAIDTSFVEILSKNVERGCSQKSAELVSEYFEKAGPAIIDFYLCRKSEILKDKNAKKLYLPMIEKLILASKNISISAAGGEHIKRTKQGLQTIKHLMDLSKKNSKNSDTDGHPSIMSQLITNPTEESLNKLAISVQNSKAIEILTPSQTKALLSSTKKLLATGDIDQLVSTAAVFSGESKEYSKAAAQMLSLFSTWLNKQESISIPYTSVREFYSKLATYFRSFERYQELKYISDSLLNLSSKAKSSTESAVNYPGLLKDSLELELGIIRAQPDSQASPKLISKLERLVVSNLSSEKYDEAIDLITRVLEVLFDVNNITHNTPIAEVKHMASISQCILFMARIYTKRPDTLSSLTSANTCKEHQSIILELLLWNFVGSASPSKNDLAAIIVRSLSSDGNLRPDSRLRPYIAYFFVTGSLYSGQEFNPDSLVEQLIADDSLPETFYVKSMTYFSLSIANHSNQQKVAYICNAVQDLSQFLSLTRHPILYKTEIEAISSFLDSHMFHDQKNGLLLQFIDSLRNDLSQDMSDLSELECSYRLDIARSYLYLGFSGVVGQQLLTANKLLTQAVSSPIQYAFLLAMETEYSASIDRRDDAVSCLSRLQKHISSSPILSEPLSAGRNANESSHQFQQRIILYCRVTEAFSSVWSITGAKELAIVAMLNLTRLLPGLLKRPGYSFWSLSSMLMDVHFRIAKLYEQLGIVKEAIYHIHEAIKLAESTECFLAQSQYLTFEAELSVKMDKQEDAKSILHRCEEIFDEDKQVVPLAKKGIEFLNIIYSTAFYLQRQNMFAEERLYYDMAESVYGDLQYPDDSKSVESISRRVSELSLKTAPIRRAIGLESVRNKLIRNHAYSLEEQGLVDVATNILVTDHVIGPASPVKSPSKIRSTENVATREEILFKISQSRNCFVKAKKVLLLDPVFGVLQDSAISVPSVNTDIGGGSNRKSSLTNMPTNAQCAEAVKHLVRARSILTENLEKIKEVCTNTELVDMSNILNNVSILLSAVCTAQEKSLYSYFSHLELTKASSVLSERQIAILREQDASNYLDWPNQDRKEAAGQYKPIAVGSLDGNHFGSKIPDNWLVVSLNIAPATGNLIVSRYEKERDPFIITLPLNRHSSRDVDEVSFSYNDGLQRLRDIISRSNDSADISRTSQIHTPDAKRAWWHERFEMDKELESLLYESQFCWLGGFRGILDSEVPDKKLAEKFVKDFKQILDRYLPSRANTLRPRRGVRSAGAANKGVPQQPVDLSPRVFELFLTLGHPDTLEDPGLLEDLVYFVLDIIQFHGEQNAYDELDIDQLVVDVEEALRSYHTRYGKVTNKKNYDHVILVLDKKCQQFPWESIPLLRKRSVSRVPSLAILNKLLSARKSSSYSPPGNDVFYVLNPSKDLIRTQERFEEPFKNMSGWQGIVSRAPSEDEIVNALNEKDLFIYVGHGGGERYIRSAKIKGLKKCCPTLLFGCSSGLVQEAGEYDPYGTCMSFMASECPMLLANMWDVTDKDIDTFSRNMLERWGVLSGQRATVDNGRYNVAQAVAMTRDDCTLKFLTGAAPVIYGLPLESAISYD"

     misc_feature    3331..4560
                     /gene="ESP1"
                     /locus_tag="AWJ20_4184"
                     /note="Peptidase family C50; Region: Peptidase_C50;
                     pfam03568"
                     /db_xref="CDD:427370"
ORIGIN      

atgtcaatatcgaactcagcatccttgataacatcaactctattgagatgttctgcattgaaaataatacccgcgattgatacaagctttgtcgagattctctctaaaaatgttgaaagaggatgctcacaaaaatctgctgaattggtatctgaatattttgaaaaggcaggtcctgccattattgacttttacttgtgccgtaaatcagagattttgaaagacaaaaatgcgaagaagctatacctaccaatgattgaaaaactaattctggcttctaaaaatatcagtatttcagcagccggtggggaacacatcaaaagaactaaacaaggattacaaacaatcaagcatctcatggatctctcaaagaagaactcaaagaatagtgacacagacggccatcccagtattatgagccaacttattacaaatcccactgaagagtcacttaataagctagcaatatctgttcagaattcgaaggctatcgagattttaactccatctcaaacaaaggctctattgtcatcgactaaaaaactgcttgccactggagatattgatcagctagtatctactgctgcggtattctctggtgaaagcaaagaatattcaaaggcggctgcgcaaatgttatcgctcttttcgacttggttaaacaaacaggaaagcatatccataccatatacatctgtacgtgagttttattccaagcttgcaacctactttcgatcattcgaacgctatcaagagctcaagtacatatcagatagtctgctcaatcttagctcaaaagccaaatcatcaacagaaagcgcagtcaactatccaggtttattaaaggattcactggaactggaactgggaataattcgggctcaaccggattcacaagctagtcctaagctaatttcaaaactcgaaaggttagtggtaagcaatctctcatcggagaaatacgacgaagcaatagaccttataactagggtattggaagtactatttgatgtcaataacatcacccataatactccaatagccgaagtcaaacatatggcctcaatatcacaatgcatattgttcatggcccgaatatacacaaagcgacccgatacattatcctctttaacttcggccaatacttgcaaagagcaccagtcaataattttagaacttttattgtggaactttgtgggcagcgcaagcccttcaaaaaatgatttggcggccatcatagttcgctcactttcatcagatggcaatcttcgccctgactctcggttacggccatatatcgcatatttttttgtcaccgggtcattgtactcaggccaagaattcaacccggattctcttgttgaacagctgatagcggatgactcactccccgaaacattttatgttaagagcatgacatatttctcgttatctattgcaaaccattcgaaccaacaaaaggttgcttatatctgtaacgcagttcaagacttatcgcagtttctgtcgttaacacgccatcccattttatacaaaaccgaaatagaggcaatttcttcatttttagattctcacatgtttcatgatcagaagaatggtttattattacaatttattgattccctgcggaatgatttgagccaagacatgtctgatttgtctgagctggaatgctcctatcgattggatattgccaggtcttatctatatttgggcttttctggcgtggtgggacagcaactcttgacagctaataagcttcttacccaggctgtatcatcaccaatacagtacgcatttctgcttgccatggaaacagaatattctgcatcaatagaccgtagagacgatgctgtgtcatgtctttcaagacttcaaaagcacatttcgagcagtcctattttaagtgaaccactttcggcgggtcgtaatgcgaatgaatcatcccaccagtttcagcagcgtattattctctattgtagggtaacagaggcgttctccagcgtatggtctataacgggtgctaaggaattggcaattgttgcaatgttaaatcttactcgtttattacctggccttctaaagcgaccagggtacagtttttggagtctctcaagtatgctcatggatgttcattttcgaattgccaaactctatgaacagcttggaatcgtcaaagaagcgatatatcatattcatgaagcgataaagctggcagaatccacggaatgctttctagcccaatcccaatatttgacatttgaagcagagttgtcggtaaagatggacaaacaagaggatgccaaaagcattttacatcgatgcgaggagattttcgatgaagacaaacaggtcgtacctttggctaagaaaggtattgaatttctcaatattatttattcaacagcgttttatcttcagcgccaaaatatgttcgctgaagaacgactctattatgatatggccgagtcggtgtacggagatcttcagtatccggacgatagtaagagtgtggaaagtatctcgagaagagtctctgaattaagccttaaaacagctccgatccgtagggcgattggcttggagtctgttcgcaataagcttatcagaaatcatgcatacagcctggaagaacaggggcttgttgatgttgcaaccaatattttagtaacagatcacgtcattggccccgcatcaccagtgaaatcgccatctaagattaggagcacggagaatgtggccacgagagaggagattctgtttaaaatatcgcaatcgagaaattgctttgtgaaagcaaaaaaggtccttttactagatccagtatttggcgtcctacaggactcggctatttcagttccatctgtgaacacagatataggaggtggcagcaatcggaagtcctcattgacaaacatgcctactaatgctcaatgtgcagaagcggttaaacaccttgttcgagctagatcaatcctaactgagaatttagagaaaatcaaagaggtctgtacaaatactgagctggtagatatgtcaaacatccttaacaatgtatccatattactgtctgctgtttgtactgctcaagaaaaatctctttacagctatttctcgcatcttgagttaacgaaagcctcttcagttctgagcgaaagacagattgctattttgcgagagcaggatgcttcaaactatctagattggccaaaccaggatcgtaaagaggcagccggtcagtataagccgattgctgtcggcagtctggatggcaatcacttcggaagcaaaattccagacaactggttagtagtttcgctgaatatcgctcctgctacgggcaatcttatagtctcgcggtatgagaaagaacgagacccttttataatcacactgcctctgaacaggcatagtagcagggatgtggatgaggtatccttttcatacaatgatggtttacagagactccgagatattatttctcgcagcaatgactctgcagatatttctagaacatctcagattcacaccccagatgcgaagagagcttggtggcacgagaggtttgagatggataaagagcttgaatctttattatatgaatcgcagttctgctggcttggaggatttaggggtattttggactcggaagtacctgataaaaagcttgctgagaagtttgtgaaagattttaagcaaatactagacagatacttgccatctagagccaatacactgcggccacgaaggggcgtcagatcagctggagctgcaaataaaggtgtccctcagcaacctgtggatctaagccctcgggtattcgagctcttcttgactctgggacatcctgatactttggaggatcctgggcttctagaagatttagtttattttgttctcgatattattcagttccatggagagcaaaatgcctatgatgagctcgacattgaccagctggtggtggatgtagaagaagccctacgtagttatcacacacgttatggaaaagttacgaacaagaaaaattacgaccatgtcatcctggtgctagacaaaaaatgccaacaatttccatgggagtcaattccattattgagaaagcggtctgtaagtcgagttccatcactagcaattctcaacaagctattgtctgctaggaaaagctcctcgtactcgcccccaggaaatgacgttttctatgttctcaacccatctaaagacttgattcgaactcaggaaagatttgaagaaccattcaaaaatatgtcaggttggcagggaatagttagtagagcaccatcagaggatgagattgttaatgctttgaacgagaaagacttgtttatttatgttggtcatggtgggggtgagcgttatattcggtcggctaaaataaaaggactgaaaaagtgctgtcctacattactctttggctgtagttcgggactagtccaggaagcaggtgaatatgatccttacgggacttgcatgagctttatggcttccgaatgtcctatgctattagccaacatgtgggacgtaaccgacaaggatatcgatactttcagtcgaaacatgctagaaagatggggtgttttgagtggccagcgggcaacagttgacaatgggagatacaacgtggcccaggctgtggccatgacgagagacgattgtacattaaaatttctaactggcgcagcgcctgtcatatacggactccctttggagtctgctattagttatgactaa

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