LOCUS       XM_018879638             480 bp    mRNA    linear   PLN 07-JAN-2024
DEFINITION  Sugiyamaella lignohabitans C-8 sterol isomerase ERG2 (ERG2),
            partial mRNA.
ACCESSION   XM_018879638
VERSION     XM_018879638.1
DBLINK      BioProject: PRJNA342695
            BioSample: SAMN04417247
KEYWORDS    RefSeq.
SOURCE      Sugiyamaella lignohabitans
  ORGANISM  Sugiyamaella lignohabitans
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Saccharomycetes; Saccharomycetales; Trichomonascaceae;
            Sugiyamaella.
REFERENCE   1  (bases 1 to 480)
  AUTHORS   Bellasio,M., Peymann,A., Valli,M., Sipitzky,M., Graf,A., Sauer,M.,
            Marx,H. and Mattanovich,D.
  TITLE     Complete genome sequence and transcriptome regulation of the
            pentose utilising yeast Sugiyamaella lignohabitans
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 480)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-JAN-2024) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (bases 1 to 480)
  AUTHORS   Peymann,A. and Graf,A.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-FEB-2016) Department of Biotechnology, University of
            Natural Resources and Life Sciences, Muthgasse 18, Vienna, Vienna
            1190, Austria
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. This record is derived from an annotated genomic
            sequence (NC_031674).
            COMPLETENESS: incomplete on both ends.
FEATURES             Location/Qualifiers
     source          1..480
                     /organism="Sugiyamaella lignohabitans"
                     /mol_type="mRNA"
                     /strain="CBS 10342"
                     /type_material="culture from holotype of Candida
                     lignohabitans"
                     /db_xref="taxon:796027"
                     /chromosome="B"
     gene            <1..>480
                     /gene="ERG2"
                     /locus_tag="AWJ20_2679"
                     /db_xref="GeneID:30034616"
     CDS             1..480
                     /gene="ERG2"
                     /locus_tag="AWJ20_2679"
                     /inference="similar to AA sequence:KEGG_Orthology:K09829"
                     /note="C-8 sterol isomerase; catalyzes the isomerization
                     of the delta-8 double bond to the delta-7 position at an
                     intermediate step in ergosterol biosynthesis;
                     GO_component: GO:0005783 - endoplasmic reticulum [Evidence
                     IEA]; GO_component: GO:0005783 - endoplasmic reticulum
                     [Evidence IC] [PMID 18459942]; GO_component: GO:0005789 -
                     endoplasmic reticulum membrane [Evidence IEA];
                     GO_component: GO:0016021 - integral component of membrane
                     [Evidence IEA]; GO_component: GO:0016020 - membrane
                     [Evidence IEA]; GO_function: GO:0000247 - C-8 sterol
                     isomerase activity [Evidence IMP] [PMID 18459942];
                     GO_function: GO:0016853 - isomerase activity [Evidence
                     IEA]; GO_process: GO:0006696 - ergosterol biosynthetic
                     process [Evidence IMP] [PMID 18459942]; GO_process:
                     GO:0006629 - lipid metabolic process [Evidence IEA];
                     GO_process: GO:0006694 - steroid biosynthetic process
                     [Evidence IEA]; GO_process: GO:0008202 - steroid metabolic
                     process [Evidence IEA]; GO_process: GO:0016126 - sterol
                     biosynthetic process [Evidence IEA,IEA]"
                     /codon_start=1
                     /product="C-8 sterol isomerase ERG2"
                     /protein_id="XP_018737536.1"
                     /db_xref="GeneID:30034616"
                     /translation="

MYHELKAEYGDYINDYDESEWVFNNAGNAMGTMFVLHASISEYLIFFGTAIGTEGHTGTHFADDYFLILAGEQTAAPAQARQPEVYLPGDSHHLPCGYNKQYRMPADSWALELAQGWIPTMLPFGFMEAFTSTMDFYSLAKTVRISAVNIVGNLLRGKI"

     misc_feature    <10..462
                     /gene="ERG2"
                     /locus_tag="AWJ20_2679"
                     /note="ERG2 and Sigma1 receptor like protein; Region:
                     ERG2_Sigma1R; pfam04622"
                     /db_xref="CDD:428041"
ORIGIN      

atgtaccacgagttgaaggccgagtatggtgattatatcaatgattacgacgagtctgagtgggttttcaacaacgctggtaatgccatgggcaccatgtttgtgttacatgcttccatttctgaatacctgattttcttcggaactgctattggtaccgaaggtcatacaggaactcactttgccgacgactacttcctaattctcgctggcgagcaaactgctgctcctgctcaagcccgtcaacccgaagtataccttcccggtgactcgcatcatttgccctgtggatacaacaaacaataccgaatgcctgccgactcctgggcactcgaactggcccaaggctggatccccaccatgctccccttcggattcatggaggccttcacctcgactatggacttctactccctggccaagacagtccgtatcagtgccgtcaacattgtcggcaacctcctcaggggtaagatctaa

//