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2021-10-17 15:53:07, GGRNA.v2 : RefSeq release 207 (Jul, 2021)

LOCUS       XM_017593400           14721 bp    mRNA    linear   ROD 21-JAN-2021
DEFINITION  PREDICTED: Rattus norvegicus argonaute RISC catalytic component 3
            (Ago3), transcript variant X1, mRNA.
ACCESSION   XM_017593400
VERSION     XM_017593400.2
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051340.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Jan 21, 2021 this sequence version replaced XM_017593400.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Rattus norvegicus Annotation Release
                                           108
            Annotation Version          :: 108
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.5
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14721
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /sex="male"
                     /tissue_type="kidney"
                     /country="USA: Wisconsin, Milwaukee, Medical College of
                     Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..14721
                     /gene="Ago3"
                     /gene_synonym="Eif2c3"
                     /note="argonaute RISC catalytic component 3; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 25 ESTs, 1 long SRA read, 5 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 32 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:313593"
                     /db_xref="RGD:1309163"
     CDS             2917..4797
                     /gene="Ago3"
                     /gene_synonym="Eif2c3"
                     /codon_start=1
                     /product="protein argonaute-3 isoform X1"
                     /protein_id="XP_017448889.1"
                     /db_xref="GeneID:313593"
                     /db_xref="RGD:1309163"
                     /translation="
MCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA"
     misc_feature    2917..3258
                     /gene="Ago3"
                     /gene_synonym="Eif2c3"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(3052..3054,3139..3141,3151..3153,3205..3207,
                     3226..3228,3232..3234)
                     /gene="Ago3"
                     /gene_synonym="Eif2c3"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    3391..4668
                     /gene="Ago3"
                     /gene_synonym="Eif2c3"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(3802..3804,3814..3816,3850..3861,3868..3870,
                     3892..3894,3901..3903,3913..3915,3925..3927)
                     /gene="Ago3"
                     /gene_synonym="Eif2c3"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(4006..4008,4012..4014,4222..4224,4636..4638)
                     /gene="Ago3"
                     /gene_synonym="Eif2c3"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      
aaagaaatgactttgtagacgggactggccttaaactcacagacacacctgactctccccccacacacccccaccagcgctaggatcacaggtgtgcgccatcacagtcccgctgtgtttatcttatatccaataatttctgctttctaaatgttatggttattgattaatgtggctttctttttatatcttttgggcaagtttgacattcttttatgattaaaggattacaatgcaagcaagaagttagaaaaagatttttttttaaatgagtatgaatgttttacctccaagaatgtctatgcataatgtgcatggctggtacgcagagggccagaagaaggcatcagattccatggtactagatttctggtagccaccacgtggctgctggaaattgaaccgggctcctctggaagaggagttagctttcctaactgctgagccatctctccagccccataggtacatcctgatatgttatacagcgcttttactctataggtcagcggtgcttgttttgtttcgctcgttgttttttctgtttaatagatgaactaagccagataaataaggtcttgacttagcagattgtgtcattctccacccctatcccccactgctttttcgatttttaaagggtgtgcattttgtggtttgtttgtttggggtttttgtttatttttgaaacagggttttacgtaactctcatgtccaatcttcaggtgctataattaatgagagggcaaagtgctcttaaagtggtagttgcaatactagaaaggccatttcctcctccttcttccttctgtgtgtgtgtgtgtgttttttttttttttttaatttgttgttatttgtttttgagatagggaatggatttttaccattttgcctggctggcttggaacttgctaagtttcccttgaactcacaaaaatctcccttcctctgtctccttctaccgtgtgggtcctggagatagaactcaggtcattgggcttggcggtaagcacctctgcctgcttggccatctcaccagccctattccttgagtcctagatcctgccctagtttcattaagatctttttagtgggtcccggtagtgcatgcctttagtcctagcactgtggaggcaggacaggcagagccacatagggagttccaggccagccaaggctacatggtgcgatcctatctcacagaaaaacaacaaaaattcaacaatgagaagacagagagaaaattaatatagttttccccctaaggactttgctgttttaaagtaattttcgggctggagacatggctcagtggttaagagcactgactgctcttccagaggacctgagcgttcaattcccagcaaccacatggtggctcacaatcatctgtaatgggatccgatgccctcttctggtgtatctgaagacagctagtgtgtactcaaataaataaaaaataaaaaaataaaataaataaattttcaccgatttcgtcatatgctttgccatttttcaggtatgatgcaccgctttgcttcttgtattttttgtgtgaaggcagagtctcactgtatagtatggctcaagttggtttcaaactttccatcctcctgcctccacctttcaggtgtcaagtgccaggattataagatgtgcctcttctgtttttatgtactgtctctgtgtggatgcttactttctgtctgtagcttaactttgaatgagatgtattctctgaagctcctggtagaagacggtaggagggtcattagttgtactttagtagcaagataatttcctggctttctctgcttgaggactccatccagaagagtgggtagcctcaccccgtctcccctgctttccagtactttcagtgatgtaagtgctgactccattgggggtgcctctgctttgccattagtttatagctttcctgcacagttcagattaagaaattacagagcaatcataactggatcatttgtagaaaggtagtctttctgggactatctaagctactctcgatataccctgatgacatgtttatacatcctttctctttttctatctgagagtcccctactccatttcagttccagacgtgacttttaagataggacacttcctttttgaaagtgaaatgtgatgtttccccatagatttccttatacttattgacattctccagcgttcagatatgagttcttgtatagattttgcaagcctgaataatcagggccatatttacttacaatgtggcattttctggggggtgggggggaggttaattgctcaatcttagtacttttcttgttgatatgtatagtatcttggaaaaagatgaagaaattgggactaaattgctgttttgtttctaccaaaacttaaaaggttagctttcaaaattaataaaggatttctaaataacccattggtcaaagaagtcacaaaggaaatttgaattttgaacaaaacggtagttaataatatatatcaaaacgggtatgattgatttaagcaatgcttagaaaaatttaaaactttaatgacccactagaacagaagagaagcatcagtaacctgagcatttatctaaaactgttagaaaattaaacgcaaagagactagaaggaaataagaaataaaaacaggagataatgaactaaaacggaaatttagtcagtagggaggcatcacgggttcttaagaaaggtagtgacatgatcgtgtttgttttccagaaagagacctctggcagcagtttggagaatagatagaggaaaaaggctaatctgagaagccagtaagggcttctcaatcactagttcagatgaataattagaagctcagaggactggaagtgaagtttctgccactgccttttacaaagcacagcctgtcattcagttcatgtgtgaagttcttgacattcacaacatcgatgagcaacccagacccctgaccgattctcatcgggtaaaattcactaaggagataaaaggtctgaaggttgaagtgactcattgtggaacaatgagacggaaataccgtgtctgtaatgtaacaagaaggcctgccagccaccaaacatttcctttacagctagaaaatggccaaactgtggagagaactgtagctcagtatttccgagaaaagtacacacttcagctgaagtacccacaccttccctgtctgcaagtggggcaggagcagaagcatacatacctgccactagaagtctgtaatattgtggctggacagaggtgtatcaagaaactaacagacaatcagacttctactatgattaaggcaacagcaagatctgcaccagatagacaagaggaaattagcagattggtaagaagtgcaaattatgaaacagatccatttgttcaggagtttcagtttaaagtgcgggatgagatggcccatgtgaccggtcgagtactgccagcacctatgctccagtatggaggacggaaccggacagtagcaacaccaagccacggagtatgggacatgagaggaaaacagttccacacaggagttgaaatcaaaatgtgggctatcgcttgctttgccacacagaggcagtgcagagaagaaatactgaaaggattcacagaccagcttcggaagatctccaaggatgcagggatgcccatccagggtcagccatgtttctgcaaatacgcacagggggcagacagcgtggagcccatgttccggcatctcaagaatacctactcaggactgcagctcattatcgtcatcctgcctgggaagacgccggtatatgcggaggtgaagcgtgtaggagacacacttttgggtatggccacacagtgtgtgcaagtcaagaatgtaataaaaacatctcctcaaactctttcaaacttgtgcctaaagatcaatgttaaacttggaggaatcaataatattcttgtacctcatcaaagaccttctgtgttccagcaaccagtgatcttcctgggcgcagatgtcacacacccgcctgctggtgacgggaagaagccttccattgctgctgttgtaggcagtatggatgcccatccaagcagatactgtgccacagtgagagttcagagaccccgacaggaaatcatccaggacttggcctccatggtccgggaactgctcatccaattttacaagtcaacccgattcaaacctactcggatcatcttttatcgggatggtgtttccgaaggacagtttagacaggtattatattatgagctcctggcaattcgagaagcctgtatcagtttggaaaaagactatcaacctggaataacctacattgtcgttcagaagagacatcatacgcgattgttctgtgctgatagaacagaaagggtgggaagaagcggcaacatcccagctggaaccacagtggatacagacatcactcacccgtatgaattcgacttttatctctgcagccatgctggaatacagggaaccagccgtccttctcactatcacgttctgtgggatgacaactgcttcactgcggatgaactgcagctgctgacctaccagctctgccacacctacgtgcgctgtaccaggtccgtgtcgatccctgcaccagcgtactatgctcacctggtggcgttcagagccaggtaccatctggtggacaaggagcatgacagtgctgaaggaagccatgtgtcaggacagagcaatggacgagatccacaagctcttgccaaggctgtccagattcaccaagataccttacgcacaatgtacttcgcttagcaagtccaagtgatctccgagaggaagagctggagctcgtatgtttccagtggactcagttcactggggaggcctccagccgcacagaagccaatactatgtaggggtctggaccttacgttgatccgaggaaaaatgtttactctgtcaaagaacacagcactgttgtataccagggagccagcccgctgcttttttgcagt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//

by @meso_cacase at DBCLS
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If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596. [Full Text]