LOCUS       XM_016223599            3762 bp    mRNA    linear   MAM 11-APR-2016
DEFINITION  PREDICTED: Miniopterus natalensis nuclear factor of kappa light
            polypeptide gene enhancer in B-cells 1 (NFKB1), transcript variant
            X2, mRNA.
ACCESSION   XM_016223599
VERSION     XM_016223599.1
DBLINK      BioProject: PRJNA317472
KEYWORDS    RefSeq.
SOURCE      Miniopterus natalensis
  ORGANISM  Miniopterus natalensis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera;
            Miniopteridae; Miniopterus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_015505014.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Version          :: Miniopterus natalensis Annotation
                                           Release 100
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 7.0
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3762
                     /organism="Miniopterus natalensis"
                     /mol_type="mRNA"
                     /isolate="MN2012-01"
                     /db_xref="taxon:291302"
                     /chromosome="Unknown"
                     /sex="male"
                     /tissue_type="skeletal muscle"
                     /dev_stage="adult"
                     /geo_loc_name="South Africa"
                     /collection_date="Oct-2012"
     gene            1..3762
                     /gene="NFKB1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 5 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 1 sample with support for all annotated introns"
                     /db_xref="GeneID:107545508"
     CDS             3..2915
                     /gene="NFKB1"
                     /codon_start=1
                     /product="nuclear factor NF-kappa-B p105 subunit isoform
                     X2"
                     /protein_id="XP_016079085.1"
                     /db_xref="GeneID:107545508"
                     /translation="

MAEEDPYLGGHEQMFHLDPLNHTIFNSEIFQPEMPLPTDVPYLQILEQPKQRGFRFRYVCEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKSTHLHAHSLVGKHCEDGICTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMTEACIRGYNPGLLVHPDLDYLQAEGGGDRQLTDREKEIIRQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAIYDSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGIWEGFGDFSPTDVHRQFAIVFKTPKYKDVNITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQRKRQKLMPNFSDSFGGGGGAGAGGGGMYGTGGGGGGAGSTGPGYGFPHYGFPTYSGITFHPGTTKSNAGMKHGTMDTSSKNGPEGCDKSDDREAVSPSGKVTETTEQDKGSGDRDDAVTLTYPVGVKEESSGLQDNLFLEKALQLAKRHANALFDYAVTGDVKMLLAVQRHLTAVQDENGDCVLHLAIIHLHAQLVRDLLEVTSGLVLDDIINMRNDLYQTPLHLAVITKQEAVVEDLLRAGADLSLLDRLGNSVLHLAAKEGHEKILSILLKHKKAALLIDNPNGEGLTAIHIAVLSNSMPCLLLLLAAGVDVNAPEQKSGRTALHLAVEQDNISLAGCLLLEGDAHVDSTTYDGTTPLHIAAGRGSTRMAALLKAAGADPLLENFEPLYDLDDSWAKDGDDEGVVPGTTPLDMATNWQVFDILNGKPYEPEFTPDDLLAQGDMKQLTEDTKLQLYKLLEFPDPDKNWSTLAQKLGLGILNNAFRLSPAPSKTLMDNYEVSGGTIRELMEALRQMGYTEAIEVIQAAFTSGTAAPSPTKTTTQANSLPLSPASTRQQIDELRDDSICDSGVETSFRKLSFTESLTSGSSLLTLNKMPHDYGQEGPLEGKI"

     misc_feature    123..728
                     /gene="NFKB1"
                     /note="N-terminal sub-domain of the Rel homology domain
                     (RHD) of nuclear factor of kappa B1 (NF-kappa B1); Region:
                     RHD-n_NFkB1; cd07935"
                     /db_xref="CDD:143651"
     misc_feature    order(165..167,171..176,180..185,192..203,426..428,
                     432..437,726..728)
                     /gene="NFKB1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143651"
     misc_feature    747..1052
                     /gene="NFKB1"
                     /note="IPT domain of the transcription factor NFkappaB and
                     related transcription factors. NFkappaB is considered a
                     central regulator of stress responses, activated by
                     different stressful conditions, including physical stress,
                     oxidative stress, and exposure to...; Region:
                     IPT_NFkappaB; cd01177"
                     /db_xref="CDD:238582"
     misc_feature    order(750..752,756..764,768..776,894..902,939..941,
                     975..977,1032..1034,1041..1043,1047..1049)
                     /gene="NFKB1"
                     /note="ankyrin protein binding site [polypeptide binding];
                     other site"
                     /db_xref="CDD:238582"
     misc_feature    order(756..761,765..767,804..806,810..812,816..818,
                     915..920,927..929,933..935)
                     /gene="NFKB1"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238582"
     misc_feature    order(819..821,825..827,918..923)
                     /gene="NFKB1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238582"
     misc_feature    1476..2297
                     /gene="NFKB1"
                     /note="Ankyrin repeat [Signal transduction mechanisms];
                     Region: ANKYR; COG0666"
                     /db_xref="CDD:440430"
     misc_feature    1503..1610
                     /gene="NFKB1"
                     /note="ANK repeat [structural motif]; Region: ANK repeat"
                     /db_xref="CDD:293786"
     misc_feature    1629..1727
                     /gene="NFKB1"
                     /note="ANK repeat [structural motif]; Region: ANK repeat"
                     /db_xref="CDD:293786"
     misc_feature    order(1632..1637,1644..1652,1656..1661,1671..1673,
                     1680..1682,1725..1727,1731..1733,1737..1739,1749..1754,
                     1761..1769,1773..1778,1788..1790,1797..1799,1824..1826,
                     1830..1832,1836..1838,1848..1853,1860..1868,1872..1877,
                     1887..1889,1896..1898)
                     /gene="NFKB1"
                     /note="oligomer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:293786"
     misc_feature    1731..1826
                     /gene="NFKB1"
                     /note="ANK repeat [structural motif]; Region: ANK repeat"
                     /db_xref="CDD:293786"
     misc_feature    order(1938..1940,1944..1946,1956..1961,1968..1976,
                     1980..1985,1995..1997,2004..2006,2031..2033,2040..2042,
                     2046..2048,2058..2063,2070..2078,2082..2087,2100..2102,
                     2109..2111,2136..2138,2142..2144,2148..2150,2160..2165,
                     2172..2180,2184..2189,2199..2201,2208..2210,2235..2237)
                     /gene="NFKB1"
                     /note="oligomer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:293786"
     misc_feature    1938..2033
                     /gene="NFKB1"
                     /note="ANK repeat [structural motif]; Region: ANK repeat"
                     /db_xref="CDD:293786"
     misc_feature    2040..2138
                     /gene="NFKB1"
                     /note="ANK repeat [structural motif]; Region: ANK repeat"
                     /db_xref="CDD:293786"
     misc_feature    2142..2237
                     /gene="NFKB1"
                     /note="ANK repeat [structural motif]; Region: ANK repeat"
                     /db_xref="CDD:293786"
     misc_feature    2436..2660
                     /gene="NFKB1"
                     /note="Death domain of the Nuclear Factor-KappaB1
                     precursor protein p105; Region: Death_NFkB1_p105; cd08797"
                     /db_xref="CDD:260063"
ORIGIN      

gaatggcagaagaggatccgtatttgggagggcatgaacaaatgtttcatttggatcctttgaatcatacaatatttaactcagaaatatttcaaccagagatgccactgccaacggatgtcccataccttcaaatattagagcaacctaaacagagaggatttcgtttccgatatgtctgtgaaggcccgtcccatggtggactccctggtgcatccagtgaaaagaataagaagtcctaccctcaggtcaaaatctgcaactatgtgggacctgcaaaggtgattgttcagttggtcacaaatggaaaaagcacccacctgcatgcacacagcctggtggggaagcactgcgaggatgggatctgcaccgtaactgctggacccaaggacatggtggtcggctttgcaaacctgggtatacttcatgtgacaaagaaaaaagtatttgaaacactggaagcacgaatgacagaggcatgtataaggggctataatcccggacttttggtgcatcctgatcttgactatttacaagcagaaggtggaggagaccggcagctcacagatcgggaaaaggagatcatccgccaggcagctctgcagcagacaaaggagatggacctcagcgtggtgcggctcatgtttacagctttccttccagacagcaccggtagcttcaccaggcgcctggaacccgtggtatcagacgccatctacgacagcaaagcccccaatgcgtccaacttgaaaattgtacgaatggacaggacggctggatgcgtaactggaggggaagagatttatcttctctgtgacaaggttcagaaagatgacatccagattcgattttatgaagaggaggaaaatggtggaatctgggaaggatttggagatttttccccaacagatgttcatagacaatttgccatcgtcttcaaaacaccgaagtataaagacgtcaacattaccaaaccagcctccgtgttcgtccagcttcggaggaaatctgatttggaaactagcgaaccaaaaccttttctctactaccctgaaatcaaagataaagaggaagtgcagaggaagcggcagaagctcatgcccaacttctcggacagttttggcggcggtggtggtgccggggctggaggtggaggcatgtacggcactggcggtggaggagggggcgctgggagcaccggcccagggtatggcttcccccactatggatttccaacatacagtggaattaccttccaccctggaaccactaaatctaatgctgggatgaagcatggaaccatggacacctcatctaaaaatggccctgaaggttgtgacaagagtgatgacagagaggctgtaagtccctctgggaaagtaactgaaaccacagaacaagataaggggtctggagatagggatgatgcggttactctgacgtatccagtgggagtaaaggaagagagctctgggcttcaggataatctcttcctagagaaggctctgcagcttgccaagcggcatgccaacgccctgttcgactacgcggtgacaggagatgtgaagatgctgctggctgtgcagcgccatctcactgccgtgcaggatgagaacggggactgtgtcctacacttagcaatcatccaccttcatgctcagcttgtgagggatctgctagaagtcacatctggtttggttttggatgacattatcaacatgagaaatgatctctaccagacgcccttgcacttggcagtgatcaccaagcaggaggctgtggtggaggacttgctgagggctggggccgacctgagcctcctggaccgcttgggtaactcggttttgcacctagctgccaaagaaggacatgagaaaattctcagtattttactcaagcacaaaaaggcagcactacttatcgacaaccccaatggggaaggtctgaccgccatccacatagccgtgctgagcaacagcatgccgtgtctgctgctgctgctggctgccggggtggacgtgaacgcgccggagcagaagtcgggccgcacggcgctgcacctggctgtggagcaggacaacatctccttggccggctgtctgctcctggagggtgatgcccatgtagacagtaccacctatgatggaaccacacccctgcacatagcagccgggagaggctccacccggatggcagctcttctcaaagcagcaggagcagatcccctgctggagaactttgagcctctctatgacctggatgactcttgggcaaaggatggagatgatgaaggagttgtgcctggaaccacacctctagatatggccaccaactggcaggtattcgacatattaaatgggaaaccatatgagccagagtttacacctgatgatttactggcacaaggagacatgaaacagctgactgaagatacaaagctgcagctctacaagttgctagaatttcctgatccagacaaaaactggtctactctggcccagaaattaggtctggggatactcaataatgccttccgcctgagtcccgcgccttctaaaactctcatggacaattacgaggtctctggaggaacaataagagagctgatggaggccctgagacagatgggctacaccgaagcgatcgaagtgatccaggcagccttcacctcaggaacggcagcccccagcccaaccaagaccaccactcaggccaactcgctgcctctctctcctgcctccacaagacagcaaatagatgagctgcgagacgacagcatctgtgacagcggtgtggagacatccttccgcaaactcagcttcacggagtctctgaccagcggcagctcactgctgactcttaacaaaatgccccatgattacgggcaggaaggacctctagaaggcaaaatttagccctcagcagtttccaacatcctgtaaaccaaagttgtgagattccattggcttgtccgaaagaaggaaggtgaggcgcctccaggggcgctcagaggaacaccgcggacctggacggtctggacccctccaggcctttgaaacctggcttcctttcttggctcttaaatgactttcagttcggctcacttgcagatagtatctagcggtcgcagccttcggcgggccggtgcctcggaggcaccatgtggagctttaccagctgctttctgttgtcactgctgctgcgtcccaccgtcattaaacgattaacagtccccacctggtgtccttactagccgtccatagcacagtcatgttttcagattaagaattaaggaaattcttaatattttattaagaaaattcttaatattttattaagaatattttaaatgaggtattttaaaatgagggtctatgtataattaaaaaaggcttcctgctttttctaatgtgttttatctctgatttgaaaaaagaacaggtatgtgtcaatatttaaacatgattacaatcagtgctgaaaatggtattttcccctttttctgcattttgctattgtaaatatgtttttagatcaaatactttaaaagaaaaaatgttggatttataaatgctattttttattttacttttataataaaaggaaaagcaaattgatggccttgtcttgttggctctgtactactactttccttgtaaatacgggaccgttccacatcctggttattatattcacctccctgcagagcccattttttgatccagaaataaaaattgtccaaagaaaagtgctttaacctga

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