LOCUS       XM_016223598            3765 bp    mRNA    linear   MAM 11-APR-2016
DEFINITION  PREDICTED: Miniopterus natalensis nuclear factor of kappa light
            polypeptide gene enhancer in B-cells 1 (NFKB1), transcript variant
            X1, mRNA.
ACCESSION   XM_016223598
VERSION     XM_016223598.1
DBLINK      BioProject: PRJNA317472
KEYWORDS    RefSeq.
SOURCE      Miniopterus natalensis
  ORGANISM  Miniopterus natalensis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera;
            Miniopteridae; Miniopterus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_015505014.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Version          :: Miniopterus natalensis Annotation
                                           Release 100
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 7.0
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3765
                     /organism="Miniopterus natalensis"
                     /mol_type="mRNA"
                     /isolate="MN2012-01"
                     /db_xref="taxon:291302"
                     /chromosome="Unknown"
                     /sex="male"
                     /tissue_type="skeletal muscle"
                     /dev_stage="adult"
                     /geo_loc_name="South Africa"
                     /collection_date="Oct-2012"
     gene            1..3765
                     /gene="NFKB1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 7 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 1 sample with support for all annotated introns"
                     /db_xref="GeneID:107545508"
     CDS             3..2918
                     /gene="NFKB1"
                     /codon_start=1
                     /product="nuclear factor NF-kappa-B p105 subunit isoform
                     X1"
                     /protein_id="XP_016079084.1"
                     /db_xref="GeneID:107545508"
                     /translation="

MAEEDPYLGGHEQMFHLDPLNHTIFNSEIFQPEMPLPTADVPYLQILEQPKQRGFRFRYVCEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKSTHLHAHSLVGKHCEDGICTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMTEACIRGYNPGLLVHPDLDYLQAEGGGDRQLTDREKEIIRQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAIYDSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGIWEGFGDFSPTDVHRQFAIVFKTPKYKDVNITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQRKRQKLMPNFSDSFGGGGGAGAGGGGMYGTGGGGGGAGSTGPGYGFPHYGFPTYSGITFHPGTTKSNAGMKHGTMDTSSKNGPEGCDKSDDREAVSPSGKVTETTEQDKGSGDRDDAVTLTYPVGVKEESSGLQDNLFLEKALQLAKRHANALFDYAVTGDVKMLLAVQRHLTAVQDENGDCVLHLAIIHLHAQLVRDLLEVTSGLVLDDIINMRNDLYQTPLHLAVITKQEAVVEDLLRAGADLSLLDRLGNSVLHLAAKEGHEKILSILLKHKKAALLIDNPNGEGLTAIHIAVLSNSMPCLLLLLAAGVDVNAPEQKSGRTALHLAVEQDNISLAGCLLLEGDAHVDSTTYDGTTPLHIAAGRGSTRMAALLKAAGADPLLENFEPLYDLDDSWAKDGDDEGVVPGTTPLDMATNWQVFDILNGKPYEPEFTPDDLLAQGDMKQLTEDTKLQLYKLLEFPDPDKNWSTLAQKLGLGILNNAFRLSPAPSKTLMDNYEVSGGTIRELMEALRQMGYTEAIEVIQAAFTSGTAAPSPTKTTTQANSLPLSPASTRQQIDELRDDSICDSGVETSFRKLSFTESLTSGSSLLTLNKMPHDYGQEGPLEGKI"

     misc_feature    126..731
                     /gene="NFKB1"
                     /note="N-terminal sub-domain of the Rel homology domain
                     (RHD) of nuclear factor of kappa B1 (NF-kappa B1); Region:
                     RHD-n_NFkB1; cd07935"
                     /db_xref="CDD:143651"
     misc_feature    order(168..170,174..179,183..188,195..206,429..431,
                     435..440,729..731)
                     /gene="NFKB1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143651"
     misc_feature    750..1055
                     /gene="NFKB1"
                     /note="IPT domain of the transcription factor NFkappaB and
                     related transcription factors. NFkappaB is considered a
                     central regulator of stress responses, activated by
                     different stressful conditions, including physical stress,
                     oxidative stress, and exposure to...; Region:
                     IPT_NFkappaB; cd01177"
                     /db_xref="CDD:238582"
     misc_feature    order(753..755,759..767,771..779,897..905,942..944,
                     978..980,1035..1037,1044..1046,1050..1052)
                     /gene="NFKB1"
                     /note="ankyrin protein binding site [polypeptide binding];
                     other site"
                     /db_xref="CDD:238582"
     misc_feature    order(759..764,768..770,807..809,813..815,819..821,
                     918..923,930..932,936..938)
                     /gene="NFKB1"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238582"
     misc_feature    order(822..824,828..830,921..926)
                     /gene="NFKB1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238582"
     misc_feature    1479..2300
                     /gene="NFKB1"
                     /note="Ankyrin repeat [Signal transduction mechanisms];
                     Region: ANKYR; COG0666"
                     /db_xref="CDD:440430"
     misc_feature    1506..1613
                     /gene="NFKB1"
                     /note="ANK repeat [structural motif]; Region: ANK repeat"
                     /db_xref="CDD:293786"
     misc_feature    1632..1730
                     /gene="NFKB1"
                     /note="ANK repeat [structural motif]; Region: ANK repeat"
                     /db_xref="CDD:293786"
     misc_feature    order(1635..1640,1647..1655,1659..1664,1674..1676,
                     1683..1685,1728..1730,1734..1736,1740..1742,1752..1757,
                     1764..1772,1776..1781,1791..1793,1800..1802,1827..1829,
                     1833..1835,1839..1841,1851..1856,1863..1871,1875..1880,
                     1890..1892,1899..1901)
                     /gene="NFKB1"
                     /note="oligomer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:293786"
     misc_feature    1734..1829
                     /gene="NFKB1"
                     /note="ANK repeat [structural motif]; Region: ANK repeat"
                     /db_xref="CDD:293786"
     misc_feature    order(1941..1943,1947..1949,1959..1964,1971..1979,
                     1983..1988,1998..2000,2007..2009,2034..2036,2043..2045,
                     2049..2051,2061..2066,2073..2081,2085..2090,2103..2105,
                     2112..2114,2139..2141,2145..2147,2151..2153,2163..2168,
                     2175..2183,2187..2192,2202..2204,2211..2213,2238..2240)
                     /gene="NFKB1"
                     /note="oligomer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:293786"
     misc_feature    1941..2036
                     /gene="NFKB1"
                     /note="ANK repeat [structural motif]; Region: ANK repeat"
                     /db_xref="CDD:293786"
     misc_feature    2043..2141
                     /gene="NFKB1"
                     /note="ANK repeat [structural motif]; Region: ANK repeat"
                     /db_xref="CDD:293786"
     misc_feature    2145..2240
                     /gene="NFKB1"
                     /note="ANK repeat [structural motif]; Region: ANK repeat"
                     /db_xref="CDD:293786"
     misc_feature    2439..2663
                     /gene="NFKB1"
                     /note="Death domain of the Nuclear Factor-KappaB1
                     precursor protein p105; Region: Death_NFkB1_p105; cd08797"
                     /db_xref="CDD:260063"
ORIGIN      

gaatggcagaagaggatccgtatttgggagggcatgaacaaatgtttcatttggatcctttgaatcatacaatatttaactcagaaatatttcaaccagagatgccactgccaacggcagatgtcccataccttcaaatattagagcaacctaaacagagaggatttcgtttccgatatgtctgtgaaggcccgtcccatggtggactccctggtgcatccagtgaaaagaataagaagtcctaccctcaggtcaaaatctgcaactatgtgggacctgcaaaggtgattgttcagttggtcacaaatggaaaaagcacccacctgcatgcacacagcctggtggggaagcactgcgaggatgggatctgcaccgtaactgctggacccaaggacatggtggtcggctttgcaaacctgggtatacttcatgtgacaaagaaaaaagtatttgaaacactggaagcacgaatgacagaggcatgtataaggggctataatcccggacttttggtgcatcctgatcttgactatttacaagcagaaggtggaggagaccggcagctcacagatcgggaaaaggagatcatccgccaggcagctctgcagcagacaaaggagatggacctcagcgtggtgcggctcatgtttacagctttccttccagacagcaccggtagcttcaccaggcgcctggaacccgtggtatcagacgccatctacgacagcaaagcccccaatgcgtccaacttgaaaattgtacgaatggacaggacggctggatgcgtaactggaggggaagagatttatcttctctgtgacaaggttcagaaagatgacatccagattcgattttatgaagaggaggaaaatggtggaatctgggaaggatttggagatttttccccaacagatgttcatagacaatttgccatcgtcttcaaaacaccgaagtataaagacgtcaacattaccaaaccagcctccgtgttcgtccagcttcggaggaaatctgatttggaaactagcgaaccaaaaccttttctctactaccctgaaatcaaagataaagaggaagtgcagaggaagcggcagaagctcatgcccaacttctcggacagttttggcggcggtggtggtgccggggctggaggtggaggcatgtacggcactggcggtggaggagggggcgctgggagcaccggcccagggtatggcttcccccactatggatttccaacatacagtggaattaccttccaccctggaaccactaaatctaatgctgggatgaagcatggaaccatggacacctcatctaaaaatggccctgaaggttgtgacaagagtgatgacagagaggctgtaagtccctctgggaaagtaactgaaaccacagaacaagataaggggtctggagatagggatgatgcggttactctgacgtatccagtgggagtaaaggaagagagctctgggcttcaggataatctcttcctagagaaggctctgcagcttgccaagcggcatgccaacgccctgttcgactacgcggtgacaggagatgtgaagatgctgctggctgtgcagcgccatctcactgccgtgcaggatgagaacggggactgtgtcctacacttagcaatcatccaccttcatgctcagcttgtgagggatctgctagaagtcacatctggtttggttttggatgacattatcaacatgagaaatgatctctaccagacgcccttgcacttggcagtgatcaccaagcaggaggctgtggtggaggacttgctgagggctggggccgacctgagcctcctggaccgcttgggtaactcggttttgcacctagctgccaaagaaggacatgagaaaattctcagtattttactcaagcacaaaaaggcagcactacttatcgacaaccccaatggggaaggtctgaccgccatccacatagccgtgctgagcaacagcatgccgtgtctgctgctgctgctggctgccggggtggacgtgaacgcgccggagcagaagtcgggccgcacggcgctgcacctggctgtggagcaggacaacatctccttggccggctgtctgctcctggagggtgatgcccatgtagacagtaccacctatgatggaaccacacccctgcacatagcagccgggagaggctccacccggatggcagctcttctcaaagcagcaggagcagatcccctgctggagaactttgagcctctctatgacctggatgactcttgggcaaaggatggagatgatgaaggagttgtgcctggaaccacacctctagatatggccaccaactggcaggtattcgacatattaaatgggaaaccatatgagccagagtttacacctgatgatttactggcacaaggagacatgaaacagctgactgaagatacaaagctgcagctctacaagttgctagaatttcctgatccagacaaaaactggtctactctggcccagaaattaggtctggggatactcaataatgccttccgcctgagtcccgcgccttctaaaactctcatggacaattacgaggtctctggaggaacaataagagagctgatggaggccctgagacagatgggctacaccgaagcgatcgaagtgatccaggcagccttcacctcaggaacggcagcccccagcccaaccaagaccaccactcaggccaactcgctgcctctctctcctgcctccacaagacagcaaatagatgagctgcgagacgacagcatctgtgacagcggtgtggagacatccttccgcaaactcagcttcacggagtctctgaccagcggcagctcactgctgactcttaacaaaatgccccatgattacgggcaggaaggacctctagaaggcaaaatttagccctcagcagtttccaacatcctgtaaaccaaagttgtgagattccattggcttgtccgaaagaaggaaggtgaggcgcctccaggggcgctcagaggaacaccgcggacctggacggtctggacccctccaggcctttgaaacctggcttcctttcttggctcttaaatgactttcagttcggctcacttgcagatagtatctagcggtcgcagccttcggcgggccggtgcctcggaggcaccatgtggagctttaccagctgctttctgttgtcactgctgctgcgtcccaccgtcattaaacgattaacagtccccacctggtgtccttactagccgtccatagcacagtcatgttttcagattaagaattaaggaaattcttaatattttattaagaaaattcttaatattttattaagaatattttaaatgaggtattttaaaatgagggtctatgtataattaaaaaaggcttcctgctttttctaatgtgttttatctctgatttgaaaaaagaacaggtatgtgtcaatatttaaacatgattacaatcagtgctgaaaatggtattttcccctttttctgcattttgctattgtaaatatgtttttagatcaaatactttaaaagaaaaaatgttggatttataaatgctattttttattttacttttataataaaaggaaaagcaaattgatggccttgtcttgttggctctgtactactactttccttgtaaatacgggaccgttccacatcctggttattatattcacctccctgcagagcccattttttgatccagaaataaaaattgtccaaagaaaagtgctttaacctga

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