LOCUS       XM_016189883            3971 bp    mRNA    linear   MAM 11-OCT-2023
DEFINITION  PREDICTED: Erinaceus europaeus NRDE-2, necessary for RNA
            interference, domain containing (NRDE2), mRNA.
ACCESSION   XM_016189883
VERSION     XM_016189883.2
DBLINK      BioProject: PRJNA986567
KEYWORDS    RefSeq.
SOURCE      Erinaceus europaeus (western European hedgehog)
  ORGANISM  Erinaceus europaeus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae;
            Erinaceinae; Erinaceus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_080183) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Oct 11, 2023 this sequence version replaced XM_016189883.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_950295315.1-RS_2023_10
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 10/04/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3971
                     /organism="Erinaceus europaeus"
                     /mol_type="mRNA"
                     /db_xref="taxon:9365"
                     /chromosome="22"
     gene            1..3971
                     /gene="NRDE2"
                     /note="NRDE-2, necessary for RNA interference, domain
                     containing; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 14 Proteins"
                     /db_xref="GeneID:103116885"
     CDS             79..3549
                     /gene="NRDE2"
                     /codon_start=1
                     /product="nuclear exosome regulator NRDE2"
                     /protein_id="XP_016045369.1"
                     /db_xref="GeneID:103116885"
                     /translation="

MALFPAFAAASEAPENGSAGKELDWLRNPSFCVGAITSLSQQTEEATTLVSEQLIPARISLKSESSGESDSSKKLRQASRKKKKEKKKKRKHQHHKKTRRHEQPSSSDSNSDTDSEKGRSSRGIRDHKKESEKPHQENNATADTGRRLVWLEDIQALTGDTFRTDKKPDPANWEYKSLYRGDIARYKRKGDSCLGINPKKQCISWEGTSTQKKHSHKPVERYFTKKNVGLVNMDGIAISGQTEPPSSEPVSFIPLPSSEDVAHPVTSWLNPLGIYDQSTTQRLQGHGPSEQEVKQQDAQPDRESALLKAKVEEFNRRVRETPRDIQLWMAFVAFQDEVMRSPGLYAIEEGEREKRKRSLKLTLEKKLAILERAIESNQSSVELKLAKLKLCAEFWEPSSLVKEWQKLIFLHPNNTALWRRYLLFCQSQFSTFTVSKIHSLYGKCLSTLSAVHDGSILSHPALPGTEEAMFALFLQQCHFLRQAGHTEKTISLFQAMVDFTFFKPDSVKDLPTKGQVEFFEPFWDSGEPRAGEKGARGWRAWMHQQERGGWVIISPDEEEDEPEDDDQEIRDKTLPRWQIWLAAERSRDQRHWRPWCPDKTKKQTEEDCEDPERQVLFDDIGQSLIRLSSPDLQFQLITAFLQFLGVPSGVSPPASCLYLAMDENSVFDHGLCDEKPLTFLDLSFSGISCVGRLDPWGCQRWTRGHKQEGEEFIRNLFHLVMPLFSGKERSQLCFSWLLYETAKVIWCLHTKNKKRLKSQGKNCKKLAKNLLKEMENRNDFCLWRQYAHLEWLLGNMEEARKVFDTALSIAGGRGLQDADLCELSLLYAELEVELEPDLRRATPGRAVHILTRLAESRPYEPYSGQVLAVHILKARKAYERALQDCLGESCVLHRLVSVVRCFLLFQYLTVGINAATQTYKQMFAKLKEAASVDGAGLEDSAGPRAPSRVLEAVTLTHTSLLRLHMKVSVYPLAPLRQALSEALTMYPSNPMLWRAYVQIQNKSHSASQTRRFFSAITRSTTALEPWLFAIEAEKMRRRLVETIQRIDGKEVHITIPETGLTHRIKGLFENAIRSDSGSQCPLLWRMYLNFLVSLGNKERSKGVFYKALQNCPWAKVLYLDAVEYFPDEMQEILDLMTEKELRVRLPVEELDLLLED"

     misc_feature    559..849
                     /gene="NRDE2"
                     /note="MTR4-interacting domain (MID) found in nuclear
                     exosome regulator NRDE2 and similar proteins; Region:
                     NRDE2_MID; cd22200"
                     /db_xref="CDD:412062"
     misc_feature    order(559..585,592..597,607..612,616..618,622..666,
                     673..681,685..693,715..723,733..738,742..747,754..774,
                     799..810,820..849)
                     /gene="NRDE2"
                     /note="MTR4 binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:412062"
     misc_feature    1015..2013
                     /gene="NRDE2"
                     /note="necessary for RNA interference; Region: NRDE-2;
                     pfam08424"
                     /db_xref="CDD:462472"
     misc_feature    <2581..2676
                     /gene="NRDE2"
                     /note="putative efflux pump membrane fusion protein;
                     Provisional; Region: PRK03598"
                     /db_xref="CDD:235136"
ORIGIN      

cggcctaaatgcgtcacttccggcttccgcccatcgacgccatttctgcggcggtgactagcgctgaggcctgtggtcatggcgctgttccctgcctttgcggccgccagcgaagctccagagaacgggagcgccgggaaggaattagactggctgagaaacccaagcttctgtgttggagccatcacttccttgagccaacaaacggaagaggccacaactcttgtttctgagcagttgataccagcaagaatttccctgaaatcagagtcttcaggtgaaagtgatagtagcaaaaagctcagacaagcaagcaggaaaaagaagaaagagaaaaagaaaaaaaggaagcatcagcaccacaagaaaaccaggagacatgagcagcctagtagcagtgactctaactcagatactgactctgaaaagggcagatcttccagaggcatcagagaccataagaaagaatccgagaaaccacatcaggaaaacaatgccactgctgacactggacgtcggttggtttggcttgaagacattcaggctctgactggagacaccttcagaacagacaagaaaccggatcctgccaactgggagtataaatctctctaccgaggagatatagcaagatacaagaggaaaggagactcctgccttggcattaacccgaagaaacagtgtatatcttgggaagggacttctacacagaagaagcactcacacaagcctgtggaacgctatttcacaaagaagaatgtggggttagtgaacatggatggcattgccattagcggtcagacggagcctccctcctcagagccagtctctttcattccactgccgagctcagaggatgtggcgcatcctgtcacaagctggctgaaccctctgggtatttatgatcagtccaccactcagaggctacaagggcacggtccctcagagcaagaggtgaagcagcaagacgctcagcccgaccgagagagcgcacttctcaaggccaaggtggaagaatttaacaggagggttcgggagacacctcgggacatccagctgtggatggcgttcgttgctttccaggatgaggtcatgagaagtcctggcttatatgccatcgaggaaggagagcgggagaagcggaagaggtcgctgaagctgaccctggagaagaagctggccattctggagcgggccatcgagagcaaccagagcagcgtggaactgaagctggccaagctcaagctctgcgcggagttctgggaaccctcttccctggtcaaagagtggcagaagctgatattcttacaccccaacaacacagccctctggcggagataccttttgttttgccagagccagttcagcacctttacggtgtcaaagattcacagcctgtatggcaaatgcctgagcacgctgtccgccgtgcacgatggcagcatcttatcacaccctgccctgcccggcaccgaggaggccatgtttgctctctttcttcagcagtgccacttcctccggcaagctgggcacacggagaagaccatctctttgttccaggccatggttgatttcaccttcttcaagcccgacagtgtgaaagacctgcccaccaaaggacaggtggagttctttgagcccttctgggacagtggagagcctcgggctggtgagaagggcgcacggggctggcgggcctggatgcaccagcaggaacgtggcggatgggtgatcatcagcccagatgaggaggaggatgagccagaagatgatgaccaggaaataagagataagacgctgcccaggtggcagatctggcttgctgcggagcggtcccgagaccagaggcactggcggccatggtgcccggataagaccaagaagcagactgaggaagattgtgaggatccagagaggcaggtgctgtttgatgatattgggcagtctctcatccgactctccagccctgatctacagttccagctgatcacggccttcctgcagttcctgggtgtgccttctggcgtcagtcccccagcctcctgtctctatctggccatggatgagaacagtgtctttgatcacggactttgtgacgaaaagccattgacttttcttgacctttccttctctggcatcagttgtgttggccgcctggacccgtggggctgccagcgctggaccaggggccacaagcaggagggcgaggagttcattcgcaacctcttccacctggtgatgccattgttctctggcaaggagaggtctcagctctgcttctcctggctgctgtatgagactgcaaaggtcatctggtgcctgcatacaaaaaacaagaagaggttaaagtcacaaggaaagaactgcaaaaagctagccaagaatctcctcaaggagatggagaaccgcaacgacttctgtctgtggaggcagtatgcccacctggaatggctgttaggcaatatggaagaggccaggaaggtgttcgacacggccctcagcatagcagggggcagggggctgcaggacgccgacctctgtgagctcagcctgctctatgctgagctggaggtggagctggagccggacttgaggagggccacccccggccgcgccgttcacatcctgaccaggctggctgagagcaggccctacgaaccctacagtgggcaggtcttggccgtccacattctcaaagcccggaaggcctacgagcgtgcgctgcaggactgcttgggtgagagctgtgtcttgcaccgcctggtgagcgtggtcagatgcttcttgctcttccagtatttgactgtcgggatcaatgctgccacgcagacctacaagcagatgtttgccaagctgaaggaggctgcttccgtggatggtgctgggctggaggacagcgcaggccctcgggctcccagccgggttctcgaggcggtcaccctgacacacacaagcctgctccggctacacatgaaggtcagcgtgtaccctctggcacccctgcgccaggccctctcagaggccttaacgatgtaccccagcaacccgatgctctggagggcgtacgtacagatccagaataagtcccacagtgccagccagaccagaagattcttcagtgccatcaccaggtctaccacagccttggagccttggttgtttgcaattgaagctgagaaaatgaggagaagactggtggaaactattcagaggatagatggcaaagaagtccatatcacaatcccggagactggcctgacacatcgcatcaaagggctctttgaaaatgcaatacggagcgacagtggcagccagtgccccttactgtggagaatgtacctgaattttctggtttccttaggaaataaagaaagaagcaaaggtgtattttataaagcacttcagaattgtccctgggcaaaggtgttgtacctggatgctgtggagtacttccctgacgagatgcaggagatcctggaccttatgaccgagaaagagctccgggtgcgcctgcctgtggaggagctggaccttctgctggaggactagagaccaggaggcacactcaagctgggatgtgagcccgtgttgagacctccattctggtggaagtttcttgatatgatttgtgtctggttaccagtcttaccgtacacattcttttggatgtgtaaatgacacaaaagctatttcttacatattatatatgtgtgtctatgtgcacttagagaattgtaccagtgctaactaaagctttgtgactggtgcgagttgcttcactctcctgtccaccagtaccgtcttgtcatggtgaaggcaccctctctgctactgtcatcctgcccaccctacccctttggatctcgcagttgggataaagtctgagatgagtttgactttcagccttaggctcctcccctgttggtcagcttaacagatttggtgcctgttttagccaagagcaatgtgtg

//