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2020-04-06 11:58:10, GGRNA.v2 : RefSeq release 99 (Mar, 2020)

LOCUS       XM_015246500           10536 bp    mRNA    linear   MAM 22-NOV-2019
DEFINITION  PREDICTED: Vicugna pacos argonaute RISC component 1 (AGO1),
            transcript variant X3, mRNA.
ACCESSION   XM_015246500
VERSION     XM_015246500.2
DBLINK      BioProject: PRJNA221631
KEYWORDS    RefSeq.
SOURCE      Vicugna pacos (alpaca)
  ORGANISM  Vicugna pacos
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Tylopoda;
            Camelidae; Vicugna.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_021964181.1) annotated using gene prediction method: Gnomon,
            supported by mRNA evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Nov 22, 2019 this sequence version replaced XM_015246500.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Vicugna pacos Annotation Release 102
            Annotation Version          :: 102
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.2
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10536
                     /organism="Vicugna pacos"
                     /mol_type="mRNA"
                     /isolate="Carlotta (AHFN-0088)"
                     /db_xref="taxon:30538"
                     /chromosome="13"
                     /map="unlocalized"
                     /sex="female"
                     /tissue_type="blood"
                     /dev_stage="adult"
     gene            1..10536
                     /gene="AGO1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 1 mRNA, 2 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 8 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:102541909"
     CDS             2364..4622
                     /gene="AGO1"
                     /codon_start=1
                     /product="protein argonaute-1 isoform X3"
                     /protein_id="XP_015101986.1"
                     /db_xref="GeneID:102541909"
                     /translation="
MVQHFKPQIFGDRKPVYDGKKNIYTVTALPIGNERVDFEVTIPGEGKDRIFKVSIKWLAIVSWRMLHEALVSGQIPVPLESVQALDVAMRHLASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRVSRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQSNGRDPQALAKAVQVHQDTLRTMYFA"
     misc_feature    <2364..2630
                     /gene="AGO1"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:293095"
     misc_feature    2661..2810
                     /gene="AGO1"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:285861"
     misc_feature    2811..3173
                     /gene="AGO1"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(2967..2969,3012..3014,3054..3056,3066..3068,
                     3120..3122,3141..3143,3147..3149)
                     /gene="AGO1"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    3306..4493
                     /gene="AGO1"
                     /note="Piwi_ago-like: PIWI domain, Argonaute-like
                     subfamily. Argonaute is the central component of the
                     RNA-induced silencing complex (RISC) and related
                     complexes. The PIWI domain is the C-terminal portion of
                     Argonaute and consists of two subdomains, one of...;
                     Region: Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(3726..3728,3738..3740,3774..3785,3792..3794,
                     3816..3818,3825..3827,3837..3839,3849..3851)
                     /gene="AGO1"
                     /note="5' RNA guide strand anchoring site; other site"
                     /db_xref="CDD:240015"
ORIGIN      
tgggagagaggttccctcttacttctgccttccctagtttgggggtgaaagggagggtgggggctctctcccctgttttcccaaagcctccttggagtggagggtgcctaaggctaagtctggtgtatagtcctattttgggggaagagaaggctttgaggctagagtgtctgtcccatcccccatcatttctactgagctctaggggatgtctttctcccaagactccaaacaattattctgcctgggaggctaaggagatgaatggaatgtaagaacttggggaggggaaggttgtctcttatcagctacatccttttagggtcatgtttgtcctgttcagggtttataattgttcctgctgtttttaggtgttcatgtgtttgtgtgttgtgtatgtatgtgtgttctttgtagtgtgtctatggatctatttgttcattcatttagtatctgtatagtgaacacctcctgtatgccaggcactggagattcagcactgaccaaggcagatacagtctgaatctttgaagaactcacagtctagggtggtaaggcgtgtgtgtataaagataaactgttaaggtctaagcgtgtgtttagatgtgtatagaatagagaaatgtgtccttctgtgtgtgtatatctgtctatggcttgtgtacaatttctgtccagctctttctggaataggtagccatgctagtggttaagctttcacttccccagatggctgcattctgaaggccttttccccccaggctgggcctccatttccctgtctgcagagtggggtaggcttgacaggtggttagaaggagacacagcagcttaactctgggaagcatgcccctcccttaaatggttctgacctcttcctgaccccccaactaaggatatgtcccatccccccagcttggcagacagtgaaagcagatctctggtgttaggaggttctgggctggtttatccctctctcttcccacctgggctggtcccctaccggcaagaacaatagtagatgtggagaaagaattctcttaggcagtttcccttttttctccctttcccctctagctagaaaataaaactaggggcagcaatcaggctggtggcaagagaggagaaagtagtgggagctggcgcttccctagtcctttcccaaaggcttcctctctcttaaatttgatcccttcttctgtctgggcactgtgtagaaggagctgtggactgtggagagaatcttgtgttctccttcccagagccagtcatctcttccttctccagccatcatgctaatggctgcccctccatcccaagtcctttcctgtagcttactcttgcctcagtctcctatatttagcctgtcttcattccctagctttttcttcttttgaactttttcctcattgtctccccacttgcaaccttgcttcttgcctggggccccagctctaacctgtcttgccccagcccctaacttcagcctttcttcttcccaattcaagtgtttttctgctgtgacctctagtttcagcttcttcaccagcttcccgcttcagcctctctccttcccttagtctccaaactctgtccttttagtcttttctccttttctttttctccaacatcagccattcagttgccttaatcctttctcaaacactgcccccatccttcttgccccccacccccattggccttctttggatcttcctcctacctgcggtgcagaggagcattaagatgatgctatttcatgttcagggtggtgatgagtgaagtgagcatcaggctgacagataatagggctttcttggtttgctagatagctgttggaggcagatgtcttaatctagtagaagaaagagtttttagttactggagccagatttagccccctacttaacatgtaataggaagttattatgtattcacttggtgaatttaagatagataacaggggtaattttcctactggaaagtttttaaaaaatgagcctagattgtctgagccagtagaagccctcagttggactgggtaggcaagaaagagacttcccctatagtctgctgctcctgttctaggaggccttgaccttctctgattagagtggtaagaatatacaagattctaccctcaccagcctctctgtcttatagctgcaggcgcctacctgccccctctgcagcaggtgttccaggcacctcgccggcctggcattggcactgtggggaaaccaatcaagctcctggccaattactttgaggtggacatccctaagattgacgtctaccactacgaggtggatatcaagccggataagtgtcctcgcagagtcaaccgggaagtggtggaatacatggtccagcatttcaagcctcagatctttggtgatcgcaagcccgtgtatgatggaaagaagaacatttacactgtcacagcattgcccattggcaatgaacgggttgactttgaggtgacaatccctggggaagggaaggatcgaatcttcaaggtttccatcaagtggctagccattgtgagctggcgcatgctgcatgaggccttggtcagtggccaaatccctgttcccctggagtctgtgcaagccctggatgtggccatgaggcacctggcatccatgaggtacacccctgtgggccgctccttcttctcaccgcctgagggctactaccacccgctggggggtgggcgcgaggtctggttcggctttcaccagtctgtgcgccctgccatgtggaagatgatgctcaacattgatgtctcagccaccgccttctacaaggcgcagccagtgattgagttcatgtgtgaggtgctggacatcaggaacatagatgagcagcctaagcctctcacggactctcagcgtgtgcgcttcaccaaggagatcaagggcctaaaggtggaagtgacccactgtggacagatgaagaggaaatatcgcgtgtgtaatgttactcgccgccctgccagccatcagacgtttcccttgcagctggagagtggacagactgtggaatgtacagtggcacagtatttcaagcagaaatacaaccttcagctcaagtatccccacctgccctgcctgcaggttggccaggaacaaaagcatacctacctgcctctagaggtctgtaacattgtggctgggcagcgctgcattaagaagctgaccgacaaccagacttcgaccatgataaaggctacagctaggtcggccccagacagacaggaggagatcagccgtctgatgaagaatgctagctacaacctagatccctacatccaggaatttgggatcaaggtgaaggatgacatgacggaggtgacagggcgagtgctgccggcgcccatcttgcagtacggcggccgggtgagcaggaaccgggccattgccacacccaatcagggtgtctgggacatgcgggggaaacagttctacaatgggattgagatcaaagtctgggccatcgcctgcttcgcaccccaaaaacagtgtcgagaagaggtgctcaagaacttcaccgaccagctgcggaagatttccaaggatgcaggaatgcctatccagggccaaccttgcttctgcaaatacgcgcagggggcagacagcgtggagcccatgttccggcatctcaagaacacctactcagggctgcagctcattatcgtcatcctgccagggaagacgccagtgtatgctgaagtgaaacgtgttggagatacactgttgggaatggctacacagtgtgtgcaagtgaagaatgtggtcaagacctcacctcagactctgtccaacctctgcctgaagatcaatgtcaaacttggtggcattaacaacatcctagtcccacaccagcgctctgccgtctttcaacagccagtgatattcctgggagcggatgttacacaccccccggcaggggatgggaaaaagccttcgatcacagcagtggtaggcagtatggatgcccatcccagccgttactgtgctactgtgcgagtgcagcgaccacggcaggagatcattgaagacttatcctacatgatcctccactatgagctgctggccattcgtgatgcctgcatcaaactggaaaaggactaccagcctgggatcacttatattgtggttcagaaacgccatcacacccgccttttttgtgctgacaagaatgagcgaattgggaagagtggtaacatcccagctgggaccactgtggacaccaacatcacccacccatttgagtttgacttctatctgtgcagccacgcaggcatccagggcaccagccgaccatcccattactatgtcctttgggatgacaaccgtttcacagcggatgagctccagatcttgacgtaccagctgtgccacacttacgtgcgatgcacacgctccgtctcaatcccagcacctgcctactatgctcgcttggtggctttccgggcacgataccacctagtggacaaggagcatgacagtggagaagggagccacatatcggggcagagcaatgggcgggatccccaggccctggccaaagccgtgcaggttcaccaggatactctgcgcaccatgtacttcgcttgaaggcagaacgctgttacctcactggatagaagaaagctttccaagccccaagagctgtgctgcccaaatccagaggaagcagggaggagggaggtggggtaggaagaaatgcagaaggccttgtttccttctacagagtggatgaaagagtggggaacagggccagtaagccagaccaccagccagaaatctctgatattcacctcatgtcctccacccctcaccccatcttgtcacatctggccctgaccccactggaccaagacgggcagcatcggtgcccaccatacacacaggtgtctcatgtgactcacagtgctaaagactcatgcctgacagcttggtaaggtcggctctgcagccctgcggacaaaagctggtaggtttgggtttgatactttagatgggaaagtgaggggcttgagaaagtgggtgggaggagggaagaatattttaggagccttaatcagaaaaggtctagatttgtttaagaagaaaaacgaaaccagacccagatcaatattttaggatactagatgttttaattggttgataatccagtttgtaggaagatttttaatgctaatggttttggttgctcctcccccagctgtcactcccctttccctattcctctctttccaccttttctaccccgccttacacctcctccctgtcagacaaccagcccctagtaagacttaaggcactatggcacttagctccgaagtgacatgaccctgtcttccttccgcctgctggtgggtaaccagtgccttccctgtaacggtaatgctgcagaactgcaaccttttgtaccttttgggtgggggacggggaggggtgggagaggaggtaggtggggatgaaatacccctaacccaacaagcctccagccagagcgccagctattttgcatttgaaggaattgacttccatattcattgagctttttaaaagatcatgacctcaagatggttaaaatccattgacatttgcactttcagacctgacaagtctcagagctgctgagatgactggcccctggcctttccacttatgtctcctttcttcctgtctcccattcctgggtctggagttactttcatagcatttctcactcttggtttctttttttccctgatggtcaagtctctttacgtttcaatatttcttaactggggtgtcttataacaaacgatccttaggtctaaaataagaaaaaagcaaaaactaaatgttatttttataccataacttgagtctattgccaaaatctggaaatccctcccatgcccaatgagtttacatcccagaaacattgagccatcagaaggaactatatacctgacttgttctttggcctggctagttagggggtggttatctccccagggtggggctcaggctccacccttcctctgtgcagataatatctttttcttgctacaggctccctcttctgcactgccctgcactctttcctgcaaatgcatcttcccttcctctggactgttttctgacactttggctcatcccagatttcagcgtgtcctgtggataggctggggattttgctgctccctattgcttctgtttacacaaatgaatttttcctggtttcccactagggcatgtgagtgggtagcatgggcttttttttttttttttttttttccatctccctgggtagagatggggtttggctgtcttgcagaactggaaaagtagggggttctagcttggtgcctgtgaccttgaagcaaggctccctctttccttgactgttcatttttttcctgtcccactgtttgggatgcggagttcagcttcagtgtggaaattcctctttttgaggaacctgggcttggatttgccctaatctggtgatgaagccatgacactttagacctagcttgtgctcagaggccagccagaggaaggtcggtctgaatacgggcctgtgcagttagagctaccatttcccctccccagcagcccttgtacagacccagatttgctatgcaaaacagtctatcccaggttcttttctggttggctacttcattcagcaacttcacaaaacgtagcacaaacattgattatggagaaggcatcaggactgttgagtaactcctcctttacttcttttgtactggtatgggatgccccatgggcacagcccagctgaagaacagaatggagggctctgggaggaggcagctcactggagagcctacattccttacacaagtgcctaaagagagtgatgccaacactccatctgccctgtccatcgccttcatacactgtctacttcgtgttcagtcaccctttggggaggggagctctcttgggacagtgggctctgcatgttctcttcttgggtgtgttttggggctgggatcagggcagcattcctggaggatccagtcattcaccagcatttgcaaatatccattgggagctggtggtagccacctactctcagcaacgagtttgtgttctctcttttttctctctttgcctcactctctccagttgggttttgaactggggcttgaaatgtgtattttagccctttggcattgtatatgccatttaggaaataaaagcaagaaaaacagcttgggcaatggcaagaaaatgacttcttgctgtgattttctttcttttcttttcttcttttttttaatctttgaaacttgaaaaatgaccttgaggattattcttgtttgaaaggtggtgcatgcagattgagcagtggtgttggcagcaagctttggctttctgggatttggttaaagtggtgcttcttacttaagctttgaggaattgctggggggaccccagcctcatcctcttaaacaggtctcttctccctttctttcacttttttgccttccttttccccttctctcttcctctgatctcttttaattttttattttatttattttttgttgttgttcactcagcttgctggctggcctgtctgcctatgtgataatgaattctctgcatggctacaatgatcccaccgttagctggcaaggtcaggcttagctccttggctgtaggagaccaagaatctgtttcccaggcccagtgatgtccaccctgggctgtactgccctccaacttacatgagggcattagcagaaggcctgtccaactagcatgataccaggagggcttctggcaacttccacacttgtccactctttggagttggtttctctcattgctttttctagatctggtttcatttctctcttcttggggcctcccttttctgaggatgtcctagagttgagctacttggtcatccggagttggagggttaggagatggacataggggaagaagagagtgataggaagaaaatggagagagtgtggcttaaatgtgggaaaggagggcattgatcttattgatcacttttccagtctagcctgactcattgggggttgaggtgctactgctagccactggggataatcctggggctgttgttcctgcgaacttaggcttagaataatgctgaagaagaaggtacctaaaagtatgacacctcccttaaaagttccggttctttcctattcagtagatcctctctggcctcctctttggctaagcaatgatgttgttggatagttttctttttcttgtccagaattctgtaaatgaggctagcaagatggacagccacggagacactttgacttcttagctggcccaggggatatctgcaaggctgactggacaatgtttttagacttggcatcatgtgtaataaagaaggatgaaagttccttccccttcagggtagaaagtcatctcaaactaactaaaatgttgttttggaaactacattggggaagttatttttatttatatttactgggcctaggccaatccaggatggtagctgggatgccttccttcttaaagtctgatcatggcagggttttgcagggcactgtttcctctttggccttctaagcagactggggagaagggattctctggttttctctccctccctccccccaccatttattaggacttaccttctccctgggcagggagagaggctaggttggtgctctccccttactctactccttagaacctctagctgctgtttgggagcccaagaaaggggatggagggaatgagctcaaaagaaaagaaaagaaaacaaaacaaaaaacagaataatgtggggaaggcagatttccttctttaaaaaggaaaataggaaaccctccaaggattgtgcaagtaaagacaatgtgtcgaatgcactgagtcccctggtgtagtagcaataaggaaaaatgaaatgactttcctgtgcacacagtccagcctgattggtgtgtgatgttgcacttagcagccatctggtgggcatgtgtgactactctgggtttcactttagtttctaaactttttatctctctcaagtccagcatggatggggaaatgttccttgaaccccacagctgtgtacttgtttgcatttgtttccccttgagacttgtgtttgtgtcctgctttgagctgtaccttgtccagtccattgtaaaattatcccagcagctgtaatgtacagttccttctgaagcaagcagcagcagcacaattctgtgttttataaagacaacagtggcttctatttctaaagtgcggtctctctcctttttttcttagcaaagaaaattcttgggatgaattatatctctgataggttttagattagaataatagattgatataagagtagaaccatcacttactaaaaggaggacagtgggtaaatcaaattccagagtgttgaaactgcagatcatatgtaatcatatttcatagggcctccacttattcttcattcaacaaacatgcaaagcactgtatcccacagtattgtggggaagtaggcaggcacaattcaaaaatgaggaaaatagctccttaaggagcttaaaaagtttggtgggggatgtgagtggtcatatggttcccaggtaccatttagagagagcgattgagggactgaacaagctgtaagtcagtagcaatgaaatagcaaagggcagacttgatagatgctcaggagatagacttatttggactcagtgaatgatggaacgggaagagagaagtagaggctaatgctcactctgcttgagcaagtaagtgtattgggacagtcctctagccaagattaggggaaaggggaggcaatagaaggaaggtggtgaattttgcgaagaaatacaattaaccttgtatagactcaacttttaggttcccaaggggcaacaaggttaaggtttccagtaaacacaatgttttggtgctcagggaagactacaaaactgcagttatagacatgggattcacattcatataaatggtagttaaagccattggagtgaacaagttggcttagaaaaagagtagagcatgagaaacctagtgtgcaactctaggaaacacagtttaagggatgaggagaggaagcaaaatggaaaatgactgtcagattactggtaaataccttgtatatttttgcttgatttaatgaggtgggagattagtcaagagagtagaataggattcaagaaaaatgttattaacatcatgacaactgattttcaccatgaaaactgaaaagagggtatttttctacgtagtttaccatcctccaccccgtctttgggatcttataactattggtcattctccaatatttcttaaaaatgaacattggaaaaacctaacttaaataacgttaagactgggacttccaagttgttcaccaccacctccacctccagcttccttctatcctcaggagatacttgtaaaagaataaaataaacaaacctaattttgttcctaa
//

by @meso_cacase at DBCLS
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If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596. [Full Text]