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2021-10-17 15:12:26, GGRNA.v2 : RefSeq release 207 (Jul, 2021)

LOCUS       XM_008764024           14685 bp    mRNA    linear   ROD 21-JAN-2021
DEFINITION  PREDICTED: Rattus norvegicus argonaute RISC catalytic component 3
            (Ago3), transcript variant X2, mRNA.
ACCESSION   XM_008764024
VERSION     XM_008764024.3
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051340.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Jan 21, 2021 this sequence version replaced XM_008764024.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Rattus norvegicus Annotation Release
                                           108
            Annotation Version          :: 108
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.5
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14685
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /sex="male"
                     /tissue_type="kidney"
                     /country="USA: Wisconsin, Milwaukee, Medical College of
                     Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..14685
                     /gene="Ago3"
                     /gene_synonym="Eif2c3"
                     /note="argonaute RISC catalytic component 3; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 25 ESTs, 1 long SRA read, 5 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 45 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:313593"
                     /db_xref="RGD:1309163"
     CDS             2881..4761
                     /gene="Ago3"
                     /gene_synonym="Eif2c3"
                     /codon_start=1
                     /product="protein argonaute-3 isoform X1"
                     /protein_id="XP_008762246.1"
                     /db_xref="GeneID:313593"
                     /db_xref="RGD:1309163"
                     /translation="
MCEVLDIHNIDEQPRPLTDSHRVKFTKEIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYTLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVRSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVIKTSPQTLSNLCLKINVKLGGINNILVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHVSGQSNGRDPQALAKAVQIHQDTLRTMYFA"
     misc_feature    2881..3222
                     /gene="Ago3"
                     /gene_synonym="Eif2c3"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(3016..3018,3103..3105,3115..3117,3169..3171,
                     3190..3192,3196..3198)
                     /gene="Ago3"
                     /gene_synonym="Eif2c3"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    3355..4632
                     /gene="Ago3"
                     /gene_synonym="Eif2c3"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(3766..3768,3778..3780,3814..3825,3832..3834,
                     3856..3858,3865..3867,3877..3879,3889..3891)
                     /gene="Ago3"
                     /gene_synonym="Eif2c3"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(3970..3972,3976..3978,4186..4188,4600..4602)
                     /gene="Ago3"
                     /gene_synonym="Eif2c3"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      
aaagaaatgactttgtagacgggactggccttaaactcacagacacacctgactctccccccacacacccccaccagcgctaggatcacaggtgtgcgccatcacagtcccgctgtgtttatcttatatccaataatttctgctttctaaatgttatggttattgattaatgtggctttctttttatatcttttgggcaagtttgacattcttttatgattaaaggattacaatgcaagcaagaagttagaaaaagatttttttttaaatgagtatgaatgttttacctccaagaatgtctatgcataatgtgcatggctggtacgcagagggccagaagaaggcatcagattccatggtactagatttctggtagccaccacgtggctgctggaaattgaaccgggctcctctggaagaggagttagctttcctaactgctgagccatctctccagccccataggtacatcctgatatgttatacagcgcttttactctataggtcagcggtgcttgttttgtttcgctcgttgttttttctgtttaatagatgaactaagccagataaataaggtcttgacttagcagattgtgtcattctccacccctatcccccactgctttttcgatttttaaagggtgtgcattttgtggtttgtttgtttggggtttttgtttatttttgaaacagggttttacgtaactctcatgtccaatcttcaggtgctataattaatgagagggcaaagtgctcttaaagtggtagttgcaatactagaaaggccatttcctcctccttcttccttctgtgtgtgtgtgtgtgttttttttttttttttaatttgttgttatttgtttttgagatagggaatggatttttaccattttgcctggctggcttggaacttgctaagtttcccttgaactcacaaaaatctcccttcctctgtctccttctaccgtgtgggtcctggagatagaactcaggtcattgggcttggcggtaagcacctctgcctgcttggccatctcaccagccctattccttgagtcctagatcctgccctagtttcattaagatctttttagtgggtcccggtagtgcatgcctttagtcctagcactgtggaggcaggacaggcagagccacatagggagttccaggccagccaaggctacatggtgcgatcctatctcacagaaaaacaacaaaaattcaacaatgagaagacagagagaaaattaatatagttttccccctaaggactttgctgttttaaagtaattttcgggctggagacatggctcagtggttaagagcactgactgctcttccagaggacctgagcgttcaattcccagcaaccacatggtggctcacaatcatctgtaatgggatccgatgccctcttctggtgtatctgaagacagctagtgtgtactcaaataaataaaaaataaaaaaataaaataaataaattttcaccgatttcgtcatatgctttgccatttttcaggtatgatgcaccgctttgcttcttgtattttttgtgtgaaggcagagtctcactgtatagtatggctcaagttggtttcaaactttccatcctcctgcctccacctttcaggtgtcaagtgccaggattataagatgtgcctcttctgtttttatgtactgtctctgtgtggatgcttactttctgtctgtagcttaactttgaatgagatgtattctctgaagctcctggtagaagacggtaggagggtcattagttgtactttagtagcaagataatttcctggctttctctgcttgaggactccatccagaagagtgggtagcctcaccccgtctcccctgctttccagtactttcagtgatgtaagtgctgactccattgggggtgcctctgctttgccattagtttatagctttcctgcacagttcagattaagaaattacagagcaatcataactggatcatttgtagaaaggtagtctttctgggactatctaagctactctcgatataccctgatgacatgtttatacatcctttctctttttctatctgagagtcccctactccatttcagttccagacgtgacttttaagataggacacttcctttttgaaagtgaaatgtgatgtttccccatagatttccttatacttattgacattctccagcgttcagatatgagttcttgtatagattttgcaagcctgaataatcagggccatatttacttacaatgtggcattttctggggggtgggggggaggttaattgctcaatcttagtacttttcttgttgatatgtatagtatcttggaaaaagatgaagaaattgggactaaattgctgttttgtttctaccaaaacttaaaaggttagctttcaaaattaataaaggatttctaaataacccattggtcaaagaagtcacaaaggaaatttgaattttgaacaaaacggtagttaataatatatatcaaaacgggtatgattgatttaagcaatgcttagaaaaatttaaaactttaatgacccactagaacagaagagaagcatcagtaacctgagcatttatctaaaactgttagaaaattaaacgcaaagagactagaaggaaataagaaataaaaacaggagataatgaactaaaacggaaatttagtcagtagggaggcatcacgggttcttaagaaaggtagtgacatgatcgtgtttgttttccagaaagagacctctggcagcagtttggagaatagatagaggaaaaaggctaatctgagaagccagtaagggcttctcaatcactagttcagtttctgccactgccttttacaaagcacagcctgtcattcagttcatgtgtgaagttcttgacattcacaacatcgatgagcaacccagacccctgaccgattctcatcgggtaaaattcactaaggagataaaaggtctgaaggttgaagtgactcattgtggaacaatgagacggaaataccgtgtctgtaatgtaacaagaaggcctgccagccaccaaacatttcctttacagctagaaaatggccaaactgtggagagaactgtagctcagtatttccgagaaaagtacacacttcagctgaagtacccacaccttccctgtctgcaagtggggcaggagcagaagcatacatacctgccactagaagtctgtaatattgtggctggacagaggtgtatcaagaaactaacagacaatcagacttctactatgattaaggcaacagcaagatctgcaccagatagacaagaggaaattagcagattggtaagaagtgcaaattatgaaacagatccatttgttcaggagtttcagtttaaagtgcgggatgagatggcccatgtgaccggtcgagtactgccagcacctatgctccagtatggaggacggaaccggacagtagcaacaccaagccacggagtatgggacatgagaggaaaacagttccacacaggagttgaaatcaaaatgtgggctatcgcttgctttgccacacagaggcagtgcagagaagaaatactgaaaggattcacagaccagcttcggaagatctccaaggatgcagggatgcccatccagggtcagccatgtttctgcaaatacgcacagggggcagacagcgtggagcccatgttccggcatctcaagaatacctactcaggactgcagctcattatcgtcatcctgcctgggaagacgccggtatatgcggaggtgaagcgtgtaggagacacacttttgggtatggccacacagtgtgtgcaagtcaagaatgtaataaaaacatctcctcaaactctttcaaacttgtgcctaaagatcaatgttaaacttggaggaatcaataatattcttgtacctcatcaaagaccttctgtgttccagcaaccagtgatcttcctgggcgcagatgtcacacacccgcctgctggtgacgggaagaagccttccattgctgctgttgtaggcagtatggatgcccatccaagcagatactgtgccacagtgagagttcagagaccccgacaggaaatcatccaggacttggcctccatggtccgggaactgctcatccaattttacaagtcaacccgattcaaacctactcggatcatcttttatcgggatggtgtttccgaaggacagtttagacaggtattatattatgagctcctggcaattcgagaagcctgtatcagtttggaaaaagactatcaacctggaataacctacattgtcgttcagaagagacatcatacgcgattgttctgtgctgatagaacagaaagggtgggaagaagcggcaacatcccagctggaaccacagtggatacagacatcactcacccgtatgaattcgacttttatctctgcagccatgctggaatacagggaaccagccgtccttctcactatcacgttctgtgggatgacaactgcttcactgcggatgaactgcagctgctgacctaccagctctgccacacctacgtgcgctgtaccaggtccgtgtcgatccctgcaccagcgtactatgctcacctggtggcgttcagagccaggtaccatctggtggacaaggagcatgacagtgctgaaggaagccatgtgtcaggacagagcaatggacgagatccacaagctcttgccaaggctgtccagattcaccaagataccttacgcacaatgtacttcgcttagcaagtccaagtgatctccgagaggaagagctggagctcgtatgtttccagtggactcagttcactggggaggcctccagccgcacagaagccaatactatgtaggggtctggaccttacgttgatccgaggaaaaatgtttactctgtcaaagaacacagcactgttgtataccagggagccagcccgctgcttttttgcagtgtcctgtagaagaagcatcacggttgttcgttctca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//

by @meso_cacase at DBCLS
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If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596. [Full Text]