LOCUS       XM_008580828            3523 bp    mRNA    linear   MAM 22-JUL-2014
DEFINITION  PREDICTED: Galeopterus variegatus nuclear factor of kappa light
            polypeptide gene enhancer in B-cells 1 (NFKB1), mRNA.
ACCESSION   XM_008580828
VERSION     XM_008580828.1
DBLINK      BioProject: PRJNA253111
KEYWORDS    RefSeq.
SOURCE      Galeopterus variegatus (Sunda flying lemur)
  ORGANISM  Galeopterus variegatus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Dermoptera; Cynocephalidae;
            Galeopterus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_007726199.1) annotated using gene prediction method: Gnomon,
            supported by mRNA evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Version          :: Galeopterus variegatus Annotation
                                           Release 100
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 6.0
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3523
                     /organism="Galeopterus variegatus"
                     /mol_type="mRNA"
                     /db_xref="taxon:482537"
                     /chromosome="Unknown"
                     /sex="male"
                     /country="Indonesia: West Java"
                     /collected_by="Minoru Baba"
     gene            1..3523
                     /gene="NFKB1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 1 mRNA, 15 Proteins, and 97%
                     coverage of the annotated genomic feature by RNAseq
                     alignments"
                     /db_xref="GeneID:103597025"
     CDS             1..2880
                     /gene="NFKB1"
                     /codon_start=1
                     /product="nuclear factor NF-kappa-B p105 subunit"
                     /protein_id="XP_008579050.1"
                     /db_xref="GeneID:103597025"
                     /translation="

MYHMDPLNHPIFNPELFQPEMALSTDGPYLQILEQPKQRGFRFRYVCEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKNIHLHAHSLVGKHCEDGICTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMTEACIRGYNPGLLVHPDLAYLQAEGGGDRQLTDREKELIRQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAIYDSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGVWEGFGDFSPTDVHRQFAIVFKTPKYKDVNITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQRKRQKLMPNFSDSFGGGSGAGAGGGGMFGSGSGGGGTGSTGPGYGFPHYGFPTYGGITFHPGTTKSNAGMKHDTESKNGPESCDKSDDREAVTGSGKVIETTEQDKEACESSNGNDEVALTYTVGVKEENAGFQDNLFLEKAMQLAKRHANALFDYAVTGDVKMLLAVQRHLTAVQDENGDSVLHLAIIHLHAQLVRDLLEVTSGLVLDGIINMRNDLYQTPLHLAVITKQEDVVEDLLRTGADLSLLDRLGDSVLHLAAKEGHDKILSVLLKHKKAALLIDHPNGEGLNAIHIAVMNNSLPCLLLLVAAGADVNAQEQKSGRTALHLAVEHDNISLAGCLLLEGDAHVDSTTYDGTTPLHIAAGRGSTRLAALLKAAGADPLVENFEPLYDLDDSWEKAGEDEGVVPGTTPLDMATSWQVFDILNGKPYEPEFTSDDLLAQGDMKQLTEDAKLQLYKLLEIPDPDKNWATLAQKLGLGILNNAFRLSPAPSKTLMDNYEVSGGTVKELVEALSQMGYTEAIEVIQAAFCTSATAASSPVKTTSQARSLPLSPSSTRQQIDELQDNDSICDSGVETSFHKLSFTESLTSGSSLLTLNKMSHDYRQEGPIEGKI"

     misc_feature    82..687
                     /gene="NFKB1"
                     /note="N-terminal sub-domain of the Rel homology domain
                     (RHD) of nuclear factor of kappa B1 (NF-kappa B1); Region:
                     RHD-n_NFkB1; cd07935"
                     /db_xref="CDD:143651"
     misc_feature    order(124..126,130..135,139..144,151..162,385..387,
                     391..396,685..687)
                     /gene="NFKB1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143651"
     misc_feature    706..1011
                     /gene="NFKB1"
                     /note="IPT domain of the transcription factor NFkappaB and
                     related transcription factors. NFkappaB is considered a
                     central regulator of stress responses, activated by
                     different stressful conditions, including physical stress,
                     oxidative stress, and exposure to...; Region:
                     IPT_NFkappaB; cd01177"
                     /db_xref="CDD:238582"
     misc_feature    order(709..711,715..723,727..735,853..861,898..900,
                     934..936,991..993,1000..1002,1006..1008)
                     /gene="NFKB1"
                     /note="ankyrin protein binding site [polypeptide binding];
                     other site"
                     /db_xref="CDD:238582"
     misc_feature    order(715..720,724..726,763..765,769..771,775..777,
                     874..879,886..888,892..894)
                     /gene="NFKB1"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238582"
     misc_feature    order(778..780,784..786,877..882)
                     /gene="NFKB1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238582"
     misc_feature    <1561..1785
                     /gene="NFKB1"
                     /note="Ankyrin repeats (3 copies); Region: Ank_2;
                     pfam12796"
                     /db_xref="CDD:432791"
     misc_feature    1573..1686
                     /gene="NFKB1"
                     /note="ANK repeat [structural motif]; Region: ANK repeat"
                     /db_xref="CDD:293786"
     misc_feature    order(1696..1698,1708..1713,1720..1728,1732..1737,
                     1747..1749,1756..1758,1783..1785,1789..1791,1795..1797,
                     1807..1812,1819..1827,1831..1836,1846..1848,1855..1857,
                     1891..1893,1897..1899,1903..1905,1915..1920,1927..1935,
                     1939..1944,1954..1956,1963..1965)
                     /gene="NFKB1"
                     /note="oligomer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:293786"
     misc_feature    1696..1785
                     /gene="NFKB1"
                     /note="ANK repeat [structural motif]; Region: ANK repeat"
                     /db_xref="CDD:293786"
     misc_feature    1705..1989
                     /gene="NFKB1"
                     /note="Ankyrin repeats (3 copies); Region: Ank_2;
                     pfam12796"
                     /db_xref="CDD:432791"
     misc_feature    1789..1893
                     /gene="NFKB1"
                     /note="ANK repeat [structural motif]; Region: ANK repeat"
                     /db_xref="CDD:293786"
     misc_feature    1897..1989
                     /gene="NFKB1"
                     /note="ANK repeat [structural motif]; Region: ANK repeat"
                     /db_xref="CDD:293786"
     misc_feature    1912..>2142
                     /gene="NFKB1"
                     /note="Ankyrin repeats (3 copies); Region: Ank_2;
                     pfam12796"
                     /db_xref="CDD:432791"
     misc_feature    1999..2097
                     /gene="NFKB1"
                     /note="ANK repeat [structural motif]; Region: ANK repeat"
                     /db_xref="CDD:293786"
     misc_feature    2395..2619
                     /gene="NFKB1"
                     /note="Death domain of the Nuclear Factor-KappaB1
                     precursor protein p105; Region: Death_NFkB1_p105; cd08797"
                     /db_xref="CDD:260063"
ORIGIN      

atgtatcatatggatcctttgaatcatccaatatttaatccagagttatttcaaccagagatggcgctgtcaacagatggcccataccttcaaatattagagcaacctaaacagagaggatttcgtttccgttacgtatgtgaaggcccatcccatggtggacttcctggtgcatctagtgaaaagaacaagaagtcctaccctcaggtcaaaatctgcaactatgtgggacctgcaaaggttattgttcagttggtcacaaatggaaaaaatatccacctccatgcccacagcctggtgggaaaacactgtgaggatgggatctgcactgtaactgctggacccaaggacatggtggtcggctttgcaaacctgggtattcttcatgtgacaaagaaaaaagtatttgaaacactggaagcacggatgacagaggcatgtataaggggctataatcctggacttctggtgcatcctgatcttgcctatttgcaagcagaagggggaggagacaggcagctcacagatcgggaaaaggagctgatccgccaggcagctcttcagcagacaaaggagatggacctcagcgtggtgcggctcatgtttacagcttttcttccggatagcactggcagcttcacaaggcgcctggaacccgtggtatcagacgccatctacgacagcaaagcccccaatgcatccaacttgaaaattgtgagaatggacaggacagctggatgcgtgactggaggggaagaaatttatcttctctgtgacaaagttcagaaagatgacatccagattcgattttacgaagaggaggaaaatggtggagtctgggaaggatttggagatttttcccccacagacgttcatagacaatttgccattgtcttcaaaactccaaagtataaagatgtcaacattacaaaaccagcctccgtattcgtccaacttcggagaaaatctgatttggaaactagtgaaccaaaaccttttctctactaccctgaaatcaaagataaagaggaagtgcagaggaaacggcagaagctcatgcccaatttctcggacagttttggcggtggtagtggcgctggagctggaggcggaggcatgtttggtagtggcagtggaggagggggtactggaagtacaggtccagggtatggcttcccacattatgggtttcctacatatggtggaattaccttccatcctggaaccactaaatctaatgctgggatgaagcatgacactgaatctaaaaatggccctgaaagttgtgacaagagtgatgacagagaggctgtaacaggctctgggaaagtaattgaaaccacagaacaagataaggaggcttgcgagtccagcaatgggaacgatgaggttgctctgacgtatacagtgggagtaaaggaagagaatgctgggtttcaggataacctctttctagagaaggcaatgcagcttgccaagcggcatgccaacgcccttttcgactacgcagtgacaggggacgtgaagatgctgctggccgtccagcgccatcttactgcagtgcaggatgagaacggggacagtgtcttacacttagcaatcatccacctccatgctcagcttgtgagggatctgctagaagtcacatctggtttggttcttgatggcatcatcaacatgagaaatgacctttaccagactcccttgcacttggcagtgatcactaagcaggaagatgttgtggaggatttgctgaggactggggctgacctgagtctcctggaccgcctgggtgactctgttttgcacctagctgccaaagaaggacatgataagattctcagtgtcttactcaagcacaaaaaggcagcactacttatcgaccaccccaatggggaaggtcttaatgccattcacatagccgtgatgaacaatagcctgccatgcctgctgctgctggtggccgctggggcagatgtcaacgctcaggagcagaagtctgggcgcacagcactgcacctggctgtggagcacgacaacatctccttggcgggctgcctgctcctggagggtgatgcccatgtggacagtaccacctatgatggaactacacccctgcatatagcagctgggagagggtccacaaggctagcagctcttctcaaagcagcaggagcagatcccctggtggagaactttgagcctctctatgacctggatgactcttgggaaaaggctggagaggatgaaggagtcgtgcctggaaccacccctctagatatggccaccagctggcaggtgtttgacatattaaatgggaaaccatatgagccagagtttacatctgatgatttactggcacaaggagacatgaaacagctgaccgaagatgcaaagttgcagctctacaagttgctagaaatccctgatccagacaaaaactgggctactctggcacagaaattaggtctggggatacttaataatgccttccggctgagtcctgctccctccaagactcttatggacaactatgaggtctcggggggtacagtcaaagagctggtggaggccctgagccagatgggctacaccgaagcgatcgaagtgatccaggcggccttctgcacctcagcaaccgcagcctccagcccagtgaagaccacctctcaggcccgctcgctgcctctctcgccttcctccacacggcagcaaatagatgagcttcaagacaacgacagcatctgtgacagtggcgtggagacatccttccacaaactcagctttacagagtctctgaccagcggcagctcattgctaactcttaacaaaatgtcccatgactacaggcaggaaggacctatagaaggcaaaatttagcccgctggcgagttcccacgcaacgtaaaccagagcgctaaaattccagtgcattgtccaaaggaaggaaggtaaagtgcatccaaaggtgctcagaagaaaactggccgcctgaatcattcttgatttaatccaaggccttttaaatttggcttcctttcttggttcttaaataaattttagcttggtttacctacagatagtatctagcgatcacagcgctcagctgagctggtgcatcgttgagggtgaggtagactattgagctttaccggctgctcctggattacagctgctttctgttgtcattgctgccgtccctctgccgtttcccaccatcattaaaagttatcactgtccccacctggtattctttctagccgtccacagcatggctagatattcacattaaagattaagaaaagggattttttaaaatgatagtactttgcgtgcaataaaaaaggcttattgctttttctctgtgatttgaaaaataaaaaacatgtacttgtcaatatttaaacataattacaatcagtgctgaaaatggtatttccccccttttctgcattttgctattgtaaatatgttttttagatcaaatacttcaaaggaaaaaatgttggatttataaatgcta

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