LOCUS       XM_008072082            3588 bp    mRNA    linear   PRI 01-JUL-2017
DEFINITION  PREDICTED: Carlito syrichta nuclear factor kappa B subunit 1
            (NFKB1), transcript variant X2, mRNA.
ACCESSION   XM_008072082
VERSION     XM_008072082.1
DBLINK      BioProject: PRJNA236776
KEYWORDS    RefSeq.
SOURCE      Carlito syrichta (Philippine tarsier)
  ORGANISM  Carlito syrichta
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Tarsiiformes; Tarsiidae; Carlito.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_007258940.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Version          :: Carlito syrichta Annotation Release
                                           101
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 7.4
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3588
                     /organism="Carlito syrichta"
                     /mol_type="mRNA"
                     /isolate="Samal-C Ts95f"
                     /db_xref="taxon:1868482"
                     /chromosome="Unknown"
                     /sex="female"
                     /geo_loc_name="USA: Duke University Lemur Center, Durham,
                     NC"
     gene            1..3588
                     /gene="NFKB1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 1 mRNA, 124 ESTs, 11 Proteins, and
                     78% coverage of the annotated genomic feature by RNAseq
                     alignments"
                     /db_xref="GeneID:103274648"
     CDS             2..2893
                     /gene="NFKB1"
                     /codon_start=1
                     /product="nuclear factor NF-kappa-B p105 subunit isoform
                     X2"
                     /protein_id="XP_008070273.1"
                     /db_xref="GeneID:103274648"
                     /translation="

MAEDDSYLGRPEQMFHLDPLSHTIFNPEVFQPQMALPTDGPYLQILEQPKQRGFRFRYVCEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKNIHLHAHSLVGKHCEDGICTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMTEACIRGYNPGLLVHPDLAYLQVEGGGDRQLTDREKEVIRQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAIYDSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGVWEGFGDFSPTDVHRQFAIVFKTPKYKDVNITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQRKRQKLMPNFSDSFGGGSGAGAGGGGMFGSGGGGGGTGSTGPGYSFPPYGFPTYGGITFHHGATKSNAGMKHGTIDTESKNDFEGHDNSDNREAVNLSGKVTVTTEQDKEFGESHDGSDEVTLMYTLGSKEENAMFQDNLFLEKAMQLAKRHANALFDYAVTGDVKMLLAVQRHLTAVQDENGDSVLHLAIIHLHAQLVRDLLKVTSGLISDDIINMRNDLYQTPLHLAVITKQEDVVEDLLRAGADLSLLDRLGNSVLHLAAKEGHDKILSILLKHKMAALLIDQPNGEGLNAIHLAMMSNSLPCLLLLLAAGVDVNAQEQKSGRTALHLAVEHDNISLAGCLLLEGDARVDSITYDGTTPLHIAAGRGSTRLAALLKAAGADPLVENFEPLYDLDDSWENAGEDEGVVPGTTPLDMAVNWQVFDILNGKPYEPEFISDDSLAQGDMKQLTEDAKLQLYKLLEIPDPDKNWATLAQKLGLGILNNAFRLSPAPSKTLMDNYEVSGGTVKELVEALRQMGYTEAIEVIQAASSPVKTTSQAHSLPLSPASTRQKIDELRDNDSICDSGVETSFRKLSFTESLTSGSSLLTLNKMPPDYGQEGKI"

     misc_feature    122..727
                     /gene="NFKB1"
                     /note="N-terminal sub-domain of the Rel homology domain
                     (RHD) of nuclear factor of kappa B1 (NF-kappa B1); Region:
                     RHD-n_NFkB1; cd07935"
                     /db_xref="CDD:143651"
     misc_feature    order(164..166,170..175,179..184,191..202,425..427,
                     431..436,725..727)
                     /gene="NFKB1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143651"
     misc_feature    746..1051
                     /gene="NFKB1"
                     /note="IPT domain of the transcription factor NFkappaB and
                     related transcription factors. NFkappaB is considered a
                     central regulator of stress responses, activated by
                     different stressful conditions, including physical stress,
                     oxidative stress, and exposure to...; Region:
                     IPT_NFkappaB; cd01177"
                     /db_xref="CDD:238582"
     misc_feature    order(749..751,755..763,767..775,893..901,938..940,
                     974..976,1031..1033,1040..1042,1046..1048)
                     /gene="NFKB1"
                     /note="ankyrin protein binding site [polypeptide binding];
                     other site"
                     /db_xref="CDD:238582"
     misc_feature    order(755..760,764..766,803..805,809..811,815..817,
                     914..919,926..928,932..934)
                     /gene="NFKB1"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238582"
     misc_feature    order(818..820,824..826,917..922)
                     /gene="NFKB1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238582"
     misc_feature    1484..2272
                     /gene="NFKB1"
                     /note="Ankyrin repeat [Signal transduction mechanisms];
                     Region: ANKYR; COG0666"
                     /db_xref="CDD:440430"
     misc_feature    order(1622..1624,1628..1630,1640..1645,1652..1660,
                     1664..1669,1679..1681,1688..1690,1733..1735,1739..1741,
                     1745..1747,1757..1762,1769..1777,1781..1786,1796..1798,
                     1805..1807,1832..1834,1838..1840,1844..1846,1856..1861,
                     1868..1876,1880..1885,1895..1897,1904..1906)
                     /gene="NFKB1"
                     /note="oligomer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:293786"
     misc_feature    1622..1735
                     /gene="NFKB1"
                     /note="ANK repeat [structural motif]; Region: ANK repeat"
                     /db_xref="CDD:293786"
     misc_feature    1739..1834
                     /gene="NFKB1"
                     /note="ANK repeat [structural motif]; Region: ANK repeat"
                     /db_xref="CDD:293786"
     misc_feature    2048..2137
                     /gene="NFKB1"
                     /note="ANK repeat [structural motif]; Region: ANK repeat"
                     /db_xref="CDD:293786"
     misc_feature    2444..2668
                     /gene="NFKB1"
                     /note="Death domain of the Nuclear Factor-KappaB1
                     precursor protein p105; Region: Death_NFkB1_p105; cd08797"
                     /db_xref="CDD:260063"
ORIGIN      

aatggcagaagatgattcatatctgggaaggcctgaacaaatgtttcatttggatcctttgagtcatacaatatttaatccagaagtatttcaaccacagatggcgctgccaacggatggcccataccttcaaatattagagcaacctaaacagagaggatttcgtttccgttacgtatgtgaaggcccatcccatggtggactaccaggtgcatctagtgaaaagaacaagaagtcctaccctcaggtcaaaatctgcaattatgtgggaccagcaaaggttattgttcagttggtcacaaatggaaaaaatatccacctgcatgcccacagcctggtggggaaacactgtgaggatgggatctgcactgtaactgctggacccaaggacatggtggtcggctttgcaaacctgggtatacttcatgtgacaaagaaaaaagtatttgaaacactggaagcacgaatgacagaggcgtgtataaggggctataatcctggactcttggtgcaccctgaccttgcctatttgcaagtggaaggtggaggggaccggcagctcacagatcgggaaaaggaggtcatccgccaggcagctcttcagcagacaaaggaaatggacctcagcgtggtgcggcttatgtttacagcttttcttccagacagcactggcagcttcacaaggcgcctagaacccgtagtctcagatgccatctacgacagcaaagctcccaatgcatccaacttgaaaattgtaagaatggacaggacagctgggtgtgtgactggaggggaagaaatttatcttctctgtgacaaagttcaaaaagatgacatccagattcgattttatgaggaagaggaaaatggtggagtctgggaaggatttggagatttttcccccacagacgttcatagacaatttgccattgtcttcaaaactccaaagtataaagatgtcaacattacaaagccagcctctgtgttcgtccaacttcggaggaaatctgatttggaaactagtgaacccaaaccttttctctactaccctgaaatcaaagataaagaggaagtacagaggaaacggcagaagctcatgcccaatttttcagatagtttcggcggtggtagtggagccggagctggaggcggaggcatgtttggtagtggcggtggaggagggggcactggaagtacaggtccaggttatagcttcccaccctatggatttcctacatatggtggaattaccttccatcatggagccactaaatctaatgctgggatgaagcatggaacaatagacactgaatctaaaaatgattttgaaggtcatgacaacagtgataacagagaggctgtaaatctctctgggaaagtcactgtaaccacagagcaagataaggagttcggagagtcccacgatgggagcgatgaggttactctaatgtatacattgggatccaaggaagagaatgctatgtttcaagataacctctttctagaaaaggctatgcagcttgccaagaggcatgccaatgccctttttgactatgcggtgacaggagatgtgaagatgctgctggctgtccagcgccatctcactgctgtacaggatgaaaatggggacagtgtcttacacttagcaatcatccaccttcatgctcagcttgtgagggatctgctaaaagtcacatcgggtttgatttctgatgacattatcaacatgagaaatgatctgtaccagacgcccttgcacttggcagtgatcactaagcaggaagatgtggtggaggacttgctgagggctggtgccgacctgagccttctggaccgcttgggtaactctgttttgcacctagctgccaaagaaggacatgataaaattctcagtatcctactgaagcacaaaatggcagcactacttattgaccaacccaatggggaaggtctgaatgccattcatctagccatgatgagcaacagcctgccatgtctgctgctgctgttagccgccggggtggacgtcaacgctcaggagcagaagtctggacgcacagcgctgcacctggctgtggagcacgacaacatctccttggcgggctgcctgctcctggagggtgatgcccgtgtggacagtatcacctatgatggaactacacctctgcatatagcagctgggagagggtccaccaggctggcagctcttctcaaagcagcaggagcagatcccctagtagagaactttgagcctctctatgacctggatgactcttgggaaaatgctggagaggatgaaggagtcgtgcctggcaccacacctctagacatggctgtcaactggcaggtatttgacatattaaatgggaaaccatatgagccagagtttatatctgatgattcactagcacaaggagacatgaaacagctgactgaagatgcaaagttgcagctctataagttgctagaaattcctgatccagacaaaaactgggctaccctggcacagaaattgggtctggggatacttaataatgccttccgactgagtcctgctccttctaagacgcttatggacaactatgaggtctctggggggacagtcaaagagctggtggaggccctgagacagatgggctacactgaagccattgaagtgatccaggcagcctccagcccagtgaagaccacctcgcaggcccactcgctgcctctctcacctgcctccacaaggcagaaaatagatgagctccgagacaacgacagcatttgtgacagcggcgtggagacatccttccgcaaactcagcttcacagagtctctgaccagcggcagctcattgctaactcttaacaaaatgccccccgattatgggcaggaaggcaaaatttagcctgctggcagtttgtgtaaaccaaagccctaaacttccactgcattgtccaaaagaaggaagcaaagtgcatccaaaggtgctcagaggagagccagcctgcctgaatcatcatcaatttaacttaaggccttttaaacttggcttcctttcttggttcataaatgaattttagcttggctcacttgcagacggtatctagcaatcacagcactggactgagctgatgtagggtggggggcggcagggttaagttgcttactgagctttgccggattgctgctggatcacagttgctttctgttgttgttgctgctgtccctctgctgtgttctcacgatcattaagggtatcactgttcctacccagtgtttttttctagcacaattgtgcattcagattaaggattaagaaaagggatattttaaatcgagactaatttggtgtgcaataaaaaaaaaggcttttcgctttttctattgtgcttatctctgtgatttgaaaaaacatgtatttgtcaatatttaaacatggttacaatcagtgctgaaaatggtattttcccctttttctgcattttgctattgtaaatatgtttttttagatgaaatactttaagaaaaaaatgttggatttataaatgctattttttattttacttttataataaaagaaaaagcaaattgatgacctca

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