LOCUS       XM_007979431            6952 bp    mRNA    linear   PRI 01-DEC-2020
DEFINITION  PREDICTED: Chlorocebus sabaeus argonaute RISC component 4 (AGO4),
            transcript variant X4, mRNA.
ACCESSION   XM_007979431
VERSION     XM_007979431.2
DBLINK      BioProject: PRJNA680339
KEYWORDS    RefSeq.
SOURCE      Chlorocebus sabaeus (Cercopithecus sabaeus)
  ORGANISM  Chlorocebus sabaeus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Cercopithecidae; Cercopithecinae; Chlorocebus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_023666033.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Dec 1, 2020 this sequence version replaced XM_007979431.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Chlorocebus sabaeus Annotation
                                           Release 102
            Annotation Version          :: 102
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.5
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6952
                     /organism="Chlorocebus sabaeus"
                     /mol_type="mRNA"
                     /strain="WHO RCB 10-87"
                     /db_xref="taxon:60711"
                     /chromosome="Unknown"
                     /sex="female"
                     /tissue_type="kidney epithelium"
     gene            1..6952
                     /gene="AGO4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 2 mRNAs, 145 ESTs, 12 Proteins,
                     and 99% coverage of the annotated genomic feature by
                     RNAseq alignments, including 25 samples with support for
                     all annotated introns"
                     /db_xref="GeneID:103225126"
     CDS             290..2674
                     /gene="AGO4"
                     /codon_start=1
                     /product="protein argonaute-4 isoform X2"
                     /protein_id="XP_007977622.2"
                     /db_xref="GeneID:103225126"
                     /translation="

MVRHFKMQIFGDRQPGYDGKRNMYTAHPLPIGRDRVDMEVTLPGEGKDQTFKVSVQWVSVVSLQLLLEALAGHLNEVPDDSVQALDVITRHLPSMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWNMMLNIDVSATAFYRAQPIIEFMCEVLDIQNINEQTKPLTDSQRVKFTKEIRGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLENGQAMECTVAQYFKQKYSLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVKSNSMVGGPDPYLKEFGIVVHNEMTELTGRVLPAPMLQYGGRNKTVATPNQGVWDMRGKQFYAGIEIKVWAVACFAPQKQCREDLLKSFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFKHLKMTYVGLQLIVVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINAKLGGINNVLVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDGHPSRYCATVRVQTSRQEISQELLYSQEVIQDLTNMVRELLIQFYKSTRFKPTRIIYYRGGVSEGQMKQVAWPELIAIRKACISLEEDYRPGITYIVVQKRHHTRLFCADKTERVGKSGNVPAGTTVDSTITHPSEFDFYLCSHAGIQGTSRPSHYQVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKDHDSAEGSHVSGQSNGRDPQALAKAVQIHHDTQHTMYFA"

     misc_feature    299..553
                     /gene="AGO4"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:435368"
     misc_feature    584..736
                     /gene="AGO4"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:430160"
     misc_feature    737..1099
                     /gene="AGO4"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(893..895,938..940,980..982,992..994,1046..1048,
                     1067..1069,1073..1075)
                     /gene="AGO4"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1238..2545
                     /gene="AGO4"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1649..1651,1661..1663,1697..1708,1715..1717,
                     1739..1741,1748..1750,1760..1762,1772..1774)
                     /gene="AGO4"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(1853..1855,1859..1861,2099..2101,2513..2515)
                     /gene="AGO4"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

attcatcagagtccattcccgtggtgccttccggctatacggagagggacgcgcagttgggtgtgtggtgctggatgaagggatgaaggaggactgctgcctctaaggacctccggctagcctgtttcagccacctcgtcgtcctggccttggaactgttggaaaaccaattcgactgttagccaatcattttcaggttcagattcctaaaatagatgtgtatcactatgatgtggatattaagcctgaaaaacggcctcgtagagtcaacagggaggtagtagatacaatggtgcggcacttcaagatgcaaatatttggtgatcggcagcctgggtatgatggcaaaagaaacatgtacacagcacatccactaccaatcggacgggatagggttgatatggaggtgactcttccaggcgagggtaaagaccaaacctttaaagtgtctgttcagtgggtgtcagttgtgagccttcagttgcttttagaagctttggctgggcacttgaatgaagtcccagatgactcagtacaagcactcgatgttatcacaagacaccttccctccatgaggtacaccccagtgggccgttcctttttctcaccccctgaaggttactaccaccctctgggagggggaagggaggtctggtttggttttcatcagtctgtgagacctgccatgtggaatatgatgctcaacattgatgtatctgcaactgctttctaccgggctcagcctatcattgagttcatgtgtgaggttttagacattcagaacatcaatgaacagaccaaacctctaacagactcccagcgtgtcaagtttaccaaagaaatcagaggtctcaaagttgaggtgacccactgtggacagatgaaacgaaaataccgagtttgtaatgtgactagacggccagccagtcatcaaacttttcctttgcagctagaaaacggtcaagctatggaatgtacagtagctcaatattttaagcaaaagtatagtctgcagctgaaatacccccatcttccctgtctccaagtgggacaagaacaaaagcatacatacttgccacttgaggtctgtaatatagtggcaggacagcgatgtatcaagaagctcacagacaatcagacttccacaatgatcaaagctacagcaagatctgctcctgacagacaggaagagatcagtagactggtgaagagcaacagtatggtgggtggacctgatccataccttaaagaatttggtattgttgtccacaatgaaatgacagagctcacaggcagggtacttccagcaccaatgctgcaatatggaggccggaataaaacagtagccacacccaaccagggtgtctgggacatgcgaggaaagcagttttatgctggcattgaaattaaagtttgggcagttgcttgttttgcacctcagaaacaatgtagggaagatttactaaagagtttcactgaccaactgcgtaaaatctctaaggatgcaggaatgcccattcagggtcagccatgtttctgcaagtatgcacaaggtgcagacagtgtggagcctatgtttaaacatctgaaaatgacttatgtgggcctacagctaatagtggttatcctgcctggaaagacaccagtatatgcggaggtgaaacgtgttggagatacccttctaggtatggccacacagtgtgtccaagtaaaaaatgtagtgaagacctcacctcaaaccctttccaatctttgcctgaagataaatgcaaaacttggaggaattaacaatgtgcttgtgcctcatcaaaggccctcggtgttccagcagcctgtcatcttcctgggagcggatgtcacacaccccccagcaggggatgggaagaagccttccattgctgctgtggttggcagtatggatggccaccccagccggtattgtgccaccgttcgggtgcagacttcccggcaggagatctcccaagagctcctctacagtcaagaggtcatccaggacctgactaacatggttcgagagctgctgattcagttctacaaatccacacgcttcaaacccactcggatcatctattaccgtggaggggtatctgagggacaaatgaagcaggtagcttggccagaactaatagcaattcgaaaggcatgtattagcttggaagaagattaccggccaggaataacatatattgtggtgcaaaaaagacatcacacacgactcttctgtgcggataaaacagaaagggtagggaaaagtggcaatgtaccagcaggcactacagtggatagtaccatcacacatccatctgagtttgacttttacctctgtagtcatgcaggaattcagggaactagccgtccctcacattaccaggtcttgtgggatgacaactgcttcactgcagatgaactccagctactgacttaccagctgtgtcacacctatgtgaggtgcactcgctcagtctctattccagcccctgcatattatgcccggcttgtagcatttagggcaaggtatcatctggtggataaagatcatgacagtgcggaaggcagtcatgtgtcaggacagagcaacggccgggatcctcaggccttggctaaggctgtgcaaatccaccatgatacccagcacacgatgtattttgcctgagagtctcagaaaaagaactcaaccaatttggcaccccatgcagcctcaaaatgtttcaaatgcctaccgcctctagatcgagccaagctgacttcaggtggtcttctaccagcagctcggaatagttgcactgaatctatactttgcagcactgtctgatgcgtcaacaaaattgagccatttttttaaagtaatagatactcatagattatcttttctgatgcactggactgaatttttacctcaatgtgcaaaggctgatcagcctgaactttctaaaggactttacaagaagggtttctatggaatattttgctagctgtggtgttcaccgcatccctctagtcttagaaaagaagattattccttttttctgtagtcattgagtggggtgtatgcataagtgggagagaaaaaccaaacaatctacttcagttcagtgtaactatttaattgtgtgggtccatagactttttaatgaagatttctgactttgccactgtaaatgcctttaatgagcattaatttttgaaagtttgttacagagttttattagttttactactttatcttattgatctctgcagacttgtgctggtgcaagtacacgctgccaggcaatttgcactatatttggctgcagattcaaacaggcagttctcttatttggtcgacttttgtgaatgtgtgacataaacagatgtaatgcatgtcacagtgacagagataacactgccatgataaaagtactcatgtttcccccatttgaaaaaaataattgcttttagtatttttccaagttttcaaaagtgcccattttatgctgctgtgtggtttgttagatctaaatgatttttaaacttttctcatagaaacttaactttggcaataaacattttttaaggtctctcctcttccttccccaacagtgtagttttctaaatgagacttcggtatgattttatcagctatttcttatatatcataatctggcaatttctgaaaccaatcagaaaagacatatatttccatgcctttttaaagaattatttttacctgttttatattcacagttggtgtcctgtcactttgttttaaaataagctagaaccaggatgcttccttattggaaaggctttgccagtccttaaggtacattgagtgatgctgcaacttgcaaaaatgtaccagcatttaaaatttcttttcctgggaatcaaggtaactcacatgactacttgcagtacaaattttttgcttctctttcgacctgaaatgtacttggtgggttttccttccttttattaaactaaaactgtgtggaaaaggttgatttttcttaatagattctgaattccactcacagggagatgggattcctttctcgtcccaacaaagggagttgctctaaagcgagcatcagttaaaatgtaggggaaaatgtattctgtatgtagtgtagataatactttgtgaatggacaacagttacatagtgtcttggtagctccagccagtgtttcccagcccagagtttactgacttgtaattctctatccaggacatcaggagtgagggatggaaaaggggataaaaggcctggagccacactccatatggctgaggaaggcgctagggaaagagatagacacaatggggtgaaaacaattttgcctcccctgcctggaaactgttggtggggaaatgatggtgaagggtgtttgctagaactcatgagacgtttcaaatctcgtaaaccagccttctcaaaatcccagcaatataaagcactgtttttcttcagtcatttaaataaacttgtaaatacattgaagtttacatttccatgtgctgttgatcaatggcgccacctgtgtttgctgatgagcctggtctctgagagagagttttataatatcgatcgaggcctgttgctcattaagatgagtgcagacgtccttaatccctgcagatagtgggatgaaaagcaagttctgtaactgaagcacaacatagccaggagtgaagagatggcagatgttaatttcttaaaattttccttttttttttttttttgcaaatacctcacttggataatacaaatcaggacatgttggtgaggggctggctgctgcttttattcacacttgttcagggagagcacagagaatacccttcagcatggccactctggacccaagaggaggaaaaaacggaagcttttttaggagaaggaggactcgcaggaatccaagatgtgaagaagtcttggtggctggctggccggccagcgggcaccacacctgcacttgagtgcctcgggcttgtttattaataatgcacagaagaagcatcacttctcaccatctcctggcatgtatggagcagggagcaaggccatgttccaaaatccctgatgagcttgtcttgctctacgctcgacctcgaacaatacagcttgtaagaccgcagtcagtcctggcacgctggggtaaatcagtgtggtggtggaagaaaagccgggaggcctatttttatagaaaatagtaccactaaaggtgcaatgctgtcattttggacaaaagggaagaaatttggaagaactgggattattggcaaaaacttgctgaggggtgaatcttgaagagctaatcactgcagaaccagagttgcagcaatatgattgcgagcaagtctgaatgcatggttttactttaactcggcttgacaatttcaataggtaaccccctcgggactgactgagtcgttaagcatgtgtcaatcaatgggaggtgtgcattctctagaagtagttttaggctgtttggtttggtttggtttttgttttttaaatgcagcctgtttaggcactgtcatgtggtgtgaaagatttaaatgtagcaatgctaaagaataataatttggggataagaagtggggacattggccgggcgcggtggctcacgcctataattccagcactttgggaggccgaggtgggtggatcacctgaggtcgggagtttgagaccagcctgaccaacatggtgaaaccccatctctactaaaaatacaaaaaattagccgggcctggtggtggatgcctgcaatcccagctactcgggaggctgaggcaggagaatcgcttgaacccaggaggtggatggtgcagtgagctattactcccgcctgggcaacaagagcgaaactccatctcgaaaagaaaaaaaaaatggggacattaagagagtggtgatgacccaaatgttgaaccgattatgttttggtggtagtgttgttagctgttgaatcctgaatggcttataaagtgaattagctggcttaatgcaaccagcgttctgggcagcagaacatattcattcttactgtaaattctatttgctgcttccaaaggtgatgattttcaagcagacatgttctatatggtctgtgttttaggatctggtgcccagcctccatcagagcttacctacctggcaaagctgcctacccttagagtgggaaaatataatccactgtttaataaggctcaccctctccaccctgtcctaacggccttttgtgaatgtgctgtaatattttcttgctcaatagcaaggtggtagctctgctttcattttaagaaagtggaggctgagggcattgtatcaatactgtttcaactccaagaagttttccttgtaaaattaaaggaaagatcttgttattgattaaccattttcttatgccttgctattgacatattcatgctctttctatgtctagtggctgaaaatgtttgcatttgttcatttgactaatggtgtgatttttgtttctatattattagacctgtaatgttttaaaatgtattttattaaatttggactggatgtatgtctctagcaatacgaggtactttctaaactattaagggaggggttgtatcctcatgttgagataagatgatggtcgtttaaattttgcaatttttttttggcctgcagggatattttgtgtttatgtgtccaaaaaaggaataaattggcattcttgtgccaaaagttgtttttcctgtcaattgtctaataagtatacagtacactgtaatggcaacatacgtggttgctttttaaaaacaatttcctctgtatgagaaattttacaaagaacagtggaaaaactttgtgtttttaactcttgggactccctatttttaaaaattgctatttggtatacaattattatgtgtcaattaaaactaaaataaaacttttaaa

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