LOCUS       XM_006872726            3183 bp    mRNA    linear   MAM 19-FEB-2014
DEFINITION  PREDICTED: Chrysochloris asiatica nuclear factor of kappa light
            polypeptide gene enhancer in B-cells 1 (NFKB1), mRNA.
ACCESSION   XM_006872726
VERSION     XM_006872726.1
DBLINK      BioProject: PRJNA232768
KEYWORDS    RefSeq.
SOURCE      Chrysochloris asiatica (Cape golden mole)
  ORGANISM  Chrysochloris asiatica
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Afrotheria; Chrysochloridae; Chrysochlorinae;
            Chrysochloris.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_006408729.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Version          :: Chrysochloris asiatica Annotation
                                           Release 100
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 5.2
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3183
                     /organism="Chrysochloris asiatica"
                     /mol_type="mRNA"
                     /db_xref="taxon:185453"
                     /chromosome="Unknown"
                     /sex="female"
                     /tissue_type="Spleen"
                     /country="South Africa"
     gene            1..3183
                     /gene="NFKB1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 18 Proteins"
                     /db_xref="GeneID:102812842"
     CDS             1..3183
                     /gene="NFKB1"
                     /codon_start=1
                     /product="nuclear factor NF-kappa-B p105 subunit"
                     /protein_id="XP_006872788.1"
                     /db_xref="GeneID:102812842"
                     /translation="

MAEDDPYMIGHEQMFHLDPLTHTMFNPDLFQPEMPLPTADGPYLQILEQPKQRGFRFRYVCEGPSHGGLPGASSEKNKKSYPQVKICNYMGPAKVIVQLVTNGKNIHLHAHSLVGKHCEDGICTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMIDACIRGYNPGLLVHPELVYLQAEGGGDRQLTDREKEIIRQAALHQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAIYDSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGVWEGFGDFSPTDVHRQFAIVFKTPKYKDINITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQRKRQKLMPNFSDSFGGGSGAGAGGGGMFGSGGGGGGAGSTGPGYGFSAYGFPTYGGITFHSGTTKSNAGMKHEALGTPCKKDHETCDGSDDRDAKNLSGKVTETTEQDKESSNGPDGVTLTYTVGVKEENCRFQDNLFLEKAMQLAKRHANALFDYAVTGDVKMLLAVQRHLTAVQDENGDSVLHLAIIHLHAQLVKDLLEVTSGLVSDDIINMRNDLYQTPLHLAVITKQEDVVENLLVAGADLSLLDRLGNSVLHLAAKEGHDKILSILLQHKMAALLINHPNGDGLNAIHIAIMSNSMPCLRLLVAASADVDAQEQKSGRTALHLAVEHDNISLAGCLLLEGDAQVDSTTFDGTTPLHIAAGRGSSKLAALLKAAGADPLVENFEPLYDLDDSWERDGEDEGVIPGTTPLDMAANWQVFDILNGKPYESELTSDDLLAQGDMKQLTEDAKLQLYKLLEIPDPDKNWATLAQKLGLGILNNAFRLSPAPSKTLMDNYEVSGGTVKELVEALRQMGYTEAIEVIQTAFCSSGKTTTSSTKTPSQSHLLPLSPSSTRQQIDELRDNESICDSGVETSFHKLSFTESLTSSSSLLTLNKMPHDYGQQGSIEGIWLSGSCWDDGLINRKQGEPRDTCGSFQWTQPENASCVTSSHIAQEKNFSPLATSIKEWSVFVPSNNLFFRRCFQDSFLVFDFAEFDYD"

     misc_feature    124..729
                     /gene="NFKB1"
                     /note="N-terminal sub-domain of the Rel homology domain
                     (RHD) of nuclear factor of kappa B1 (NF-kappa B1); Region:
                     RHD-n_NFkB1; cd07935"
                     /db_xref="CDD:143651"
     misc_feature    order(166..168,172..177,181..186,193..204,427..429,
                     433..438,727..729)
                     /gene="NFKB1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:143651"
     misc_feature    748..1053
                     /gene="NFKB1"
                     /note="IPT domain of the transcription factor NFkappaB and
                     related transcription factors. NFkappaB is considered a
                     central regulator of stress responses, activated by
                     different stressful conditions, including physical stress,
                     oxidative stress, and exposure to...; Region:
                     IPT_NFkappaB; cd01177"
                     /db_xref="CDD:238582"
     misc_feature    order(751..753,757..765,769..777,895..903,940..942,
                     976..978,1033..1035,1042..1044,1048..1050)
                     /gene="NFKB1"
                     /note="ankyrin protein binding site [polypeptide binding];
                     other site"
                     /db_xref="CDD:238582"
     misc_feature    order(757..762,766..768,805..807,811..813,817..819,
                     916..921,928..930,934..936)
                     /gene="NFKB1"
                     /note="dimerization interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:238582"
     misc_feature    order(820..822,826..828,919..924)
                     /gene="NFKB1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238582"
     misc_feature    <1603..1827
                     /gene="NFKB1"
                     /note="Ankyrin repeats (3 copies); Region: Ank_2;
                     pfam12796"
                     /db_xref="CDD:432791"
     misc_feature    order(1615..1617,1621..1623,1633..1638,1645..1653,
                     1657..1662,1672..1674,1681..1683,1726..1728,1732..1734,
                     1738..1740,1750..1755,1762..1770,1774..1779,1789..1791,
                     1798..1800,1825..1827,1831..1833,1837..1839,1849..1854,
                     1861..1869,1873..1878,1888..1890,1897..1899)
                     /gene="NFKB1"
                     /note="oligomer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:293786"
     misc_feature    1615..1728
                     /gene="NFKB1"
                     /note="ANK repeat [structural motif]; Region: ANK repeat"
                     /db_xref="CDD:293786"
     misc_feature    1732..1827
                     /gene="NFKB1"
                     /note="ANK repeat [structural motif]; Region: ANK repeat"
                     /db_xref="CDD:293786"
     misc_feature    1747..2031
                     /gene="NFKB1"
                     /note="Ankyrin repeats (3 copies); Region: Ank_2;
                     pfam12796"
                     /db_xref="CDD:432791"
     misc_feature    1939..2031
                     /gene="NFKB1"
                     /note="ANK repeat [structural motif]; Region: ANK repeat"
                     /db_xref="CDD:293786"
     misc_feature    1954..>2184
                     /gene="NFKB1"
                     /note="Ankyrin repeats (3 copies); Region: Ank_2;
                     pfam12796"
                     /db_xref="CDD:432791"
     misc_feature    2041..2139
                     /gene="NFKB1"
                     /note="ANK repeat [structural motif]; Region: ANK repeat"
                     /db_xref="CDD:293786"
     misc_feature    2437..2658
                     /gene="NFKB1"
                     /note="Death domain of the Nuclear Factor-KappaB1
                     precursor protein p105; Region: Death_NFkB1_p105; cd08797"
                     /db_xref="CDD:260063"
ORIGIN      

atggcagaagacgatccatatatgatagggcatgaacaaatgtttcatttggatccactaactcatacaatgtttaatccagatttatttcaaccagaaatgccactaccaacagcagatggtccgtaccttcaaatattagaacaacctaaacagagaggatttcgtttccgttatgtatgtgagggaccatcccatggtggacttcctggtgcatctagtgaaaagaacaagaagtcttaccctcaggtcaaaatctgcaactatatgggacctgcaaaggttattgttcaactggtcacaaatggaaaaaacatccacctgcatgcacacagcctggtggggaaacactgtgaggatggaatatgtacagtgaccgctggacccaaggatatggtggttggctttgcaaacctgggtattcttcatgtaacaaagaaaaaagtatttgagacactggaagcacgaatgatagatgcttgtataagaggctataaccctggacttttagtgcatccggaacttgtctatttgcaagcagaaggtggcggagacaggcaactcacagatcgggaaaaggagatcatccgccaggctgctcttcatcagacaaaagagatggacctcagcgtggtacggctcatgtttacagcttttctcccggatagcactggcagcttcacaagacgcctggagcccgtggtatcagatgccatctacgacagcaaagcccccaatgcatccaacttgaaaattgtaagaatggaccggacagccggatgtgttactggaggagaagagatttatcttctctgtgacaaggttcagaaagatgacatacaaattcgattttatgaagaggaggaaaatggtggagtctgggaaggatttggagatttttcccccacagacgttcataggcagtttgccattgtcttcaaaaccccaaagtataaagacatcaacattacaaaaccagcctctgtgttcgtccaacttcgaaggaaatctgatttagaaactagtgaaccaaaaccttttctctactaccctgaaatcaaagataaagaggaagtgcagaggaaacggcagaagctcatgcccaacttttcagatagtttcggtggtggtagtggtgctggagctggaggtggaggcatgtttggtagtggcggtggaggagggggtgctggaagtactggcccaggatatggcttctccgcctatggatttcctacctatggtggaatcaccttccattctggaaccactaaatctaatgctgggatgaaacatgaagccttaggtacaccctgtaagaaggaccatgaaacttgtgatggaagtgatgacagagatgctaaaaatctttctgggaaagtaactgaaaccacagaacaagataaggagtctagcaatgggcctgatggggttacgctgacgtatacagtaggagtaaaggaagaaaattgtaggtttcaggataacctctttctagagaaggctatgcagcttgcaaagcggcacgccaatgccctttttgactatgcggtcacaggagatgtgaaaatgctgctggctgtccagcgccatcttactgcagtgcaggatgagaatggggacagcgttttgcacttagcaatcattcaccttcatgctcaacttgtgaaggatctgctagaagtcacgtcaggtttggtttctgatgacatcatcaacatgagaaatgatctttaccagacacctttgcacttagcagtgatcaccaagcaagaagatgtggtagagaacttgctggtggctggggctgacctaagtcttctggaccgcttgggtaattctgttttacacctagctgccaaagaaggacatgataaaattctcagcatcttactccagcacaaaatggcagcactacttatcaaccatcccaatggagacggtctgaatgccattcacatagccataatgagcaacagcatgccatgtctgcggctgctggtggctgccagcgcagatgtggacgctcaagagcagaagtctgggcgcacagcactgcacctggctgtggaacacgacaacatctccttggctggctgcctgctcctggagggtgatgctcaagtggacagcaccacctttgatgggactacacccttgcatatcgcggctgggagagggtcctccaaattggcagctcttctcaaagcagcaggagcagatcctttggtggagaattttgagcctctctatgacctggatgactcttgggaaagggatggagaggatgaaggtgtcatacctggaaccacacctttagatatggctgccaactggcaggtttttgacatattaaatgggaaaccatacgagtcagagcttacatctgatgatttactggcacaaggagacatgaaacagctgactgaagatgcaaagttgcagctctacaagttgctagaaatcccagatccagacaaaaactgggccaccctggcacagaaattaggtctaggaatacttaacaatgccttccgactgagtcccgcaccttctaaaactcttatggacaactatgaggtctctggaggaacagtaaaggaactggtagaggccctgagacagatgggctacactgaagcaattgaagtcatccagacagccttctgcagctcaggaaagacaaccaccagctcaaccaagacgccctctcagtcccacttgctgcctctctcaccttcctccacaaggcagcaaatagatgagctccgagacaacgaaagcatctgtgacagcggcgtggagacctccttccacaaactcagcttcacagagtctctgaccagcagtagctcattgctaactctgaacaaaatgccccacgattatgggcagcaaggatctatagaagggatttggctctcaggctcttgctgggatgatggccttatcaaccggaagcagggagagcccagagatacatgtgggagttttcagtggacccagcctgaaaatgcttcttgtgtcacttcttctcacattgcacaggagaaaaactttagtcctctggccacatctatcaaggagtggtccgtatttgttcccagtaacaatttgtttttccggagatgctttcaagattctttccttgtctttgactttgcagaattcgattatgattag

//