LOCUS       XM_006748057            3847 bp    mRNA    linear   MAM 30-SEP-2019
DEFINITION  PREDICTED: Leptonychotes weddellii NRDE-2, necessary for RNA
            interference, domain containing (NRDE2), mRNA.
ACCESSION   XM_006748057
VERSION     XM_006748057.2
DBLINK      BioProject: PRJNA232772
KEYWORDS    RefSeq.
SOURCE      Leptonychotes weddellii (Weddell seal)
  ORGANISM  Leptonychotes weddellii
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia;
            Pinnipedia; Phocidae; Monachinae; Lobodontini; Leptonychotes.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_006385806.1) annotated using gene prediction method: Gnomon,
            supported by mRNA evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Sep 30, 2019 this sequence version replaced XM_006748057.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Leptonychotes weddellii Annotation
                                           Release 101
            Annotation Version          :: 101
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.2
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3847
                     /organism="Leptonychotes weddellii"
                     /mol_type="mRNA"
                     /isolate="WS11-02"
                     /db_xref="taxon:9713"
                     /chromosome="Unknown"
                     /sex="female"
                     /tissue_type="liver"
     gene            1..3847
                     /gene="NRDE2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 5 mRNAs, 2 Proteins, and 99%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 5 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:102735624"
     CDS             73..3579
                     /gene="NRDE2"
                     /codon_start=1
                     /product="protein NRDE2 homolog"
                     /protein_id="XP_006748120.1"
                     /db_xref="GeneID:102735624"
                     /translation="

MALFPAFAGIGDAPNSGSARKELDWLSNPSFCVGAISSLSQQPEEAATLVSEGSPLTRSPLKSEPSDESDANGKPKQTSRKKKKEKKKKRKRHHKKTKRKRGQAGSSGSEPDSEPEEDKTSRSTGDSRRESEKPSQEGNAAADIGHRFVWLEDVQALTGETFRTDKKPDPANWEYKSLYRGDIARYKRKGDSCLGINPKKQCISWERAAAEKKPSHKRVERYFTKKSVGLMNIDGVAVGSKTEPPSSEPISFIPVKGSDDVVPPVTTWLNPLGIYDPSTTQWLQGQGPPEQESKQPDSQTDRERALLKAKVEEFNRRVRENPHDIQLWMAFVAFQDEVVRSPGLYALEAGEQEKRKRSAKLVLEKQLAVLERAIESNQSSVELQLARLKLCAEFWEPSALLREWQKLIFVHPNSTALWQKYLLFCQSQFSTFTVSKIHGLYGKCLSTLSAVQDGSILSHPALPGTEEAVFALFLQHCHFLRQAGHSEKAISLFQAMVDFTFFKPDSVKDLPTKGQVEFFEPFWDSGEPRAGEKGARGWRAWMHQQERGGWVVISPDDDDDEPEDEDQEIRDKSLPRWQIWLAAERSRDQRHWQPWRPDKTKKQTEEDCEDPERQVLFDDIAQSLIQLSSRDLQFQLVAAFLQFLGVPSGLSPLASCLYLAMDEDSIFDNGLHDEKPLTFLDLSFSGVSCVGRSDPLGCHRWTRGHNREGEEFIRNIFHLVMSLFSGQERSQLCFSWLRYEMAKVVWCLHTKNKKRLKSQGKNCKKLAKNLLKEPENRNNFCLWKQYAHLEWLLGNTEDARKVFDTALSLAGGGEPRGCEPWELGLLYAGLELELELELSPAARGAATARAVHILTRLTENGPYAPYSGPVSAVHVLKARKAYEHALQDCQGQSCGAGPPPADASHRLAGLLRCFMLFQYLTVGIEAAVRIYEQACAQLQGSVSPGGCGPDEPSCAQSPGRGLEAVTLMHTSLLRFHARVSVCPVAPLRQALSDALRWYPGNQVLWRAYVQLQSKSHTASKTRRFFDAITRSAKPLEPWLFAIEAEKTRKRLVETVQRVDGREVHATIPETGLTHRIEALFENALRSDNGSQCPLLWRMYLNFLVSLGNKERSKGVFYKALQNCPWAKTLYLDAVGHFPEEMQEVLDLMTEKELRVRLPVEELELLLED"

     misc_feature    553..840
                     /gene="NRDE2"
                     /note="MTR4-interacting domain (MID) found in nuclear
                     exosome regulator NRDE2 and similar proteins; Region:
                     NRDE2_MID; cd22200"
                     /db_xref="CDD:412062"
     misc_feature    order(553..579,586..591,601..606,610..612,616..660,
                     667..675,679..687,709..717,727..732,736..741,748..768,
                     793..804,814..840)
                     /gene="NRDE2"
                     /note="MTR4 binding site [polypeptide binding]; other
                     site"
                     /db_xref="CDD:412062"
     misc_feature    1009..2007
                     /gene="NRDE2"
                     /note="necessary for RNA interference; Region: NRDE-2;
                     pfam08424"
                     /db_xref="CDD:462472"
ORIGIN      

gcgggcctcactaccggcgtccgctcgccggcgccatttctgtcgaggggaacggcagtgcggcctgtgatcatggcgctgttcccggcctttgccggtattggtgacgctcccaacagcggcagcgccaggaaagaattagattggctgagcaacccgagcttttgtgttggagccataagctctctgagccaacaacctgaagaggctgccactctggtttctgaagggtcaccgctgacgaggagtcctctgaaatcagagccttcagatgaaagtgatgctaacggaaagcccaaacaaacaagcagaaaaaagaagaaagagaagaagaagaagaggaaacgtcaccacaagaaaaccaagagaaaacgtgggcaggccggtagcagtggctccgagccggatagtgagcctgaagaggacaaaacttccagaagcactggagacagtagaagggaatcggagaaaccaagtcaagaaggtaatgctgccgctgatattgggcatcgctttgtttggcttgaggacgttcaggctctgactggagaaaccttcagaacagataagaaaccggatccggccaactgggagtataagtctctctaccgaggagacatagcaagatacaagaggaaaggagactcctgccttggcattaaccctaagaagcagtgtatatcctgggagagggctgccgcagaaaagaagccttcacacaagcgtgttgagcgctatttcacgaagaagagcgtgggcttaatgaacattgacggagttgccgttggcagtaaaaccgaacctccctcatctgagccgatctcgtttatccccgtgaagggctcggatgatgtggttcctcccgttacgacctggttgaaccctctggggatttacgatccgtccaccacgcagtggttacaaggacagggccctccagagcaagaatcaaagcagccagactcccagacagacagagagcgcgcgctgctcaaggccaaggtggaggagttcaacaggagagtgcgggagaaccctcacgatattcagctgtggatggcgttcgttgcttttcaggacgaggtcgtgcggagccccggcctgtatgccctggaggcaggggagcaggagaagcggaagaggtctgcgaagctggtgctggagaagcagctggctgtcctggagcgggccatcgagagcaaccagagctccgtggagctgcagctggcccggctgaagctgtgcgccgagttctgggagccctcggcgctgctcagggagtggcagaaactgatctttgtacaccccaacagtacggccctctggcagaagtaccttttattttgccaaagccagttcagcaccttcaccgtgtcgaagatccacggtctttacggcaaatgcttgagcactctgtccgcggtgcaggacggcagcatcctgtcgcaccccgccctgcccggcaccgaggaggccgtgttcgctctctttcttcagcactgtcacttcctgcggcaggccggtcactcggagaaggcgatctcgctcttccaggccatggtggacttcaccttcttcaagccagacagcgtgaaagacctgcctaccaaaggacaggtggaattctttgagcccttctgggacagtggggagccccgggctggggagaagggcgcccgaggctggagagcctggatgcaccagcaggagcgaggcggctgggtggtcatcagtccagatgatgatgatgacgagccagaagacgaggaccaggaaataagagataagagtctgcccaggtggcagatctggctcgccgctgagcggtcccgagaccagagacactggcagccgtggcgccctgataagaccaagaagcaaaccgaagaagactgtgaggacccagagagacaggtgctgtttgatgacattgcgcagtctctgatccagctctccagccgggatcttcagtttcagctggtcgcggcctttctgcagttcctgggcgtgccttctggcctcagccccctggcctcctgcctctacctggccatggacgaggacagcatcttcgataacgggcttcacgatgaaaagccattgacttttctcgacctgtccttttccggcgtcagctgtgttggccgttcagacccactgggctgccatcgctggacccgcgggcacaatcgagagggcgaggagttcatccgtaacatctttcaccttgtgatgtctctgttttcaggccaggagaggtctcagctctgcttctcctggctacggtacgagatggcgaaggtcgtttggtgtctgcacactaaaaacaagaagaggttaaagtcacaaggaaagaactgcaaaaaacttgccaaaaacctcctgaaggagccagaaaaccgcaacaacttttgcctctggaagcagtacgcacatctggagtggttgctcggcaacaccgaggacgccaggaaggtgttcgacacggcgctcagcctggcggggggcggagagccgcggggctgcgagccctgggagctcggcctgctctacgcggggctggagctggagctggagctggagctgtcgccggccgcgagaggggccgccacggcccgagctgtccacatactgaccaggctgacggagaatggtccctacgcgccctactccgggccggtctcggctgttcacgttttgaaggcccggaaggcttacgaacacgcgctgcaggactgtcaggggcagagctgtggcgctgggccgcctcccgccgacgcctctcaccgcctcgccggcctgctcaggtgcttcatgctcttccagtacttgaccgtggggatcgaagccgctgtgcggatctacgagcaggcgtgtgcgcagctgcagggctccgtctccccgggcggctgtgggccggacgagcccagctgcgcgcagagcccgggccgcggcctcgaggccgtcacgctgatgcacacgagcctgctgcggttccacgcgagggtcagcgtgtgccccgtggctcctctgcggcaggcgctctcggacgccttacggtggtaccccggcaaccaggttctgtggcgggcctacgtacagcttcagagtaagtcccacacggccagtaagaccagaaggttcttcgatgccattaccaggtctgccaaacccttggagccgtggttgtttgcgattgaagccgagaaaacgaggaagaggctggtggaaaccgttcagagggtggatggcagagaggtccacgccacgattcccgagaccggcttgacgcatcggatcgaagccctgtttgaaaatgctttgcggagcgacaacggcagccagtgccccttactgtggagaatgtatttgaactttctggtctccttgggaaacaaagaaaggagcaaaggcgtgttctacaaagcacttcagaattgtccttgggcaaagacgctgtacctggatgccgtgggccacttccctgaagagatgcaggaggtcctggacctgatgacggagaaggagctccgggtgcgcctgcccgtggaggagttggagcttctactcgaggactagagaccaggaggtgttcaacagtccctgccttccgggcctcgtcgcctgcaccgctggggccgggatgtagcagacggggcacgtgtaggtgcatgtgttccaggagctctgctttccaagtctagctttaattcttagtaatttgaacctgggtcatcagtttcttagctcttgcacattttttggatgtgcaaataacacagaagctattgcttacatattatatatgtgaatgtgtaggtaagaatcatgccccatgacaatggaa

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