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2020-04-06 11:10:23, GGRNA.v2 : RefSeq release 99 (Mar, 2020)

LOCUS       XM_006212690           10619 bp    mRNA    linear   MAM 22-NOV-2019
DEFINITION  PREDICTED: Vicugna pacos argonaute RISC component 1 (AGO1),
            transcript variant X2, mRNA.
ACCESSION   XM_006212690
VERSION     XM_006212690.3
DBLINK      BioProject: PRJNA221631
KEYWORDS    RefSeq.
SOURCE      Vicugna pacos (alpaca)
  ORGANISM  Vicugna pacos
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Tylopoda;
            Camelidae; Vicugna.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_021964181.1) annotated using gene prediction method: Gnomon,
            supported by mRNA evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Nov 22, 2019 this sequence version replaced XM_006212690.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Vicugna pacos Annotation Release 102
            Annotation Version          :: 102
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.2
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10619
                     /organism="Vicugna pacos"
                     /mol_type="mRNA"
                     /isolate="Carlotta (AHFN-0088)"
                     /db_xref="taxon:30538"
                     /chromosome="13"
                     /map="unlocalized"
                     /sex="female"
                     /tissue_type="blood"
                     /dev_stage="adult"
     gene            1..10619
                     /gene="AGO1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 5 mRNAs, 43 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 38 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:102541909"
     CDS             2357..4705
                     /gene="AGO1"
                     /codon_start=1
                     /product="protein argonaute-1 isoform X2"
                     /protein_id="XP_006212752.1"
                     /db_xref="GeneID:102541909"
                     /translation="
MVQHFKPQIFGDRKPVYDGKKNIYTVTALPIGNERVDFEVTIPGEGKDRIFKVSIKWLAIVSWRMLHEALVSGQIPVPLESVQALDVAMRHLASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQSNGRDPQALAKAVQVHQDTLRTMYFA"
     misc_feature    2399..2623
                     /gene="AGO1"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:339747"
     misc_feature    2657..2803
                     /gene="AGO1"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:337161"
     misc_feature    2804..3166
                     /gene="AGO1"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(2960..2962,3005..3007,3047..3049,3059..3061,
                     3113..3115,3134..3136,3140..3142)
                     /gene="AGO1"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    3299..4576
                     /gene="AGO1"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(3710..3712,3722..3724,3758..3769,3776..3778,
                     3800..3802,3809..3811,3821..3823,3833..3835)
                     /gene="AGO1"
                     /note="5' RNA guide strand anchoring site; other site"
                     /db_xref="CDD:240015"
     misc_feature    order(3914..3916,3920..3922,4130..4132,4544..4546)
                     /gene="AGO1"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      
gaggttccctcttacttctgccttccctagtttgggggtgaaagggagggtgggggctctctcccctgttttcccaaagcctccttggagtggagggtgcctaaggctaagtctggtgtatagtcctattttgggggaagagaaggctttgaggctagagtgtctgtcccatcccccatcatttctactgagctctaggggatgtctttctcccaagactccaaacaattattctgcctgggaggctaaggagatgaatggaatgtaagaacttggggaggggaaggttgtctcttatcagctacatccttttagggtcatgtttgtcctgttcagggtttataattgttcctgctgtttttaggtgttcatgtgtttgtgtgttgtgtatgtatgtgtgttctttgtagtgtgtctatggatctatttgttcattcatttagtatctgtatagtgaacacctcctgtatgccaggcactggagattcagcactgaccaaggcagatacagtctgaatctttgaagaactcacagtctagggtggtaaggcgtgtgtgtataaagataaactgttaaggtctaagcgtgtgtttagatgtgtatagaatagagaaatgtgtccttctgtgtgtgtatatctgtctatggcttgtgtacaatttctgtccagctctttctggaataggtagccatgctagtggttaagctttcacttccccagatggctgcattctgaaggccttttccccccaggctgggcctccatttccctgtctgcagagtggggtaggcttgacaggtggttagaaggagacacagcagcttaactctgggaagcatgcccctcccttaaatggttctgacctcttcctgaccccccaactaaggatatgtcccatccccccagcttggcagacagtgaaagcagatctctggtgttaggaggttctgggctggtttatccctctctcttcccacctgggctggtcccctaccggcaagaacaatagtagatgtggagaaagaattctcttaggcagtttcccttttttctccctttcccctctagctagaaaataaaactaggggcagcaatcaggctggtggcaagagaggagaaagtagtgggagctggcgcttccctagtcctttcccaaaggcttcctctctcttaaatttgatcccttcttctgtctgggcactgtgtagaaggagctgtggactgtggagagaatcttgtgttctccttcccagagccagtcatctcttccttctccagccatcatgctaatggctgcccctccatcccaagtcctttcctgtagcttactcttgcctcagtctcctatatttagcctgtcttcattccctagctttttcttcttttgaactttttcctcattgtctccccacttgcaaccttgcttcttgcctggggccccagctctaacctgtcttgccccagcccctaacttcagcctttcttcttcccaattcaagtgtttttctgctgtgacctctagtttcagcttcttcaccagcttcccgcttcagcctctctccttcccttagtctccaaactctgtccttttagtcttttctccttttctttttctccaacatcagccattcagttgccttaatcctttctcaaacactgcccccatccttcttgccccccacccccattggccttctttggatcttcctcctacctgcggtgcagaggagcattaagatgatgctatttcatgttcagggtggtgatgagtgaagtgagcatcaggctgacagataatagggctttcttggtttgctagatagctgttggaggcagatgtcttaatctagtagaagaaagagtttttagttactggagccagatttagccccctacttaacatgtaataggaagttattatgtattcacttggtgaatttaagatagataacaggggtaattttcctactggaaagtttttaaaaaatgagcctagattgtctgagccagtagaagccctcagttggactgggtaggcaagaaagagacttcccctatagtctgctgctcctgttctaggaggccttgaccttctctgattagagtggtaagaatatacaagattctaccctcaccagcctctctgtcttatagctgcaggcgcctacctgccccctctgcagcaggtgttccaggcacctcgccggcctggcattggcactgtggggaaaccaatcaagctcctggccaattactttgaggtggacatccctaagattgacgtctaccactacgaggtggatatcaagccggataagtgtcctcgcagagtcaaccgggaagtggtggaatacatggtccagcatttcaagcctcagatctttggtgatcgcaagcccgtgtatgatggaaagaagaacatttacactgtcacagcattgcccattggcaatgaacgggttgactttgaggtgacaatccctggggaagggaaggatcgaatcttcaaggtttccatcaagtggctagccattgtgagctggcgcatgctgcatgaggccttggtcagtggccaaatccctgttcccctggagtctgtgcaagccctggatgtggccatgaggcacctggcatccatgaggtacacccctgtgggccgctccttcttctcaccgcctgagggctactaccacccgctggggggtgggcgcgaggtctggttcggctttcaccagtctgtgcgccctgccatgtggaagatgatgctcaacattgatgtctcagccaccgccttctacaaggcgcagccagtgattgagttcatgtgtgaggtgctggacatcaggaacatagatgagcagcctaagcctctcacggactctcagcgtgtgcgcttcaccaaggagatcaagggcctaaaggtggaagtgacccactgtggacagatgaagaggaaatatcgcgtgtgtaatgttactcgccgccctgccagccatcagacgtttcccttgcagctggagagtggacagactgtggaatgtacagtggcacagtatttcaagcagaaatacaaccttcagctcaagtatccccacctgccctgcctgcaggttggccaggaacaaaagcatacctacctgcctctagaggtctgtaacattgtggctgggcagcgctgcattaagaagctgaccgacaaccagacttcgaccatgataaaggctacagctaggtcggccccagacagacaggaggagatcagccgtctgatgaagaatgctagctacaacctagatccctacatccaggaatttgggatcaaggtgaaggatgacatgacggaggtgacagggcgagtgctgccggcgcccatcttgcagtacggcggccggaaccgggccattgccacacccaatcagggtgtctgggacatgcgggggaaacagttctacaatgggattgagatcaaagtctgggccatcgcctgcttcgcaccccaaaaacagtgtcgagaagaggtgctcaagaacttcaccgaccagctgcggaagatttccaaggatgcaggaatgcctatccagggccaaccttgcttctgcaaatacgcgcagggggcagacagcgtggagcccatgttccggcatctcaagaacacctactcagggctgcagctcattatcgtcatcctgccagggaagacgccagtgtatgctgaagtgaaacgtgttggagatacactgttgggaatggctacacagtgtgtgcaagtgaagaatgtggtcaagacctcacctcagactctgtccaacctctgcctgaagatcaatgtcaaacttggtggcattaacaacatcctagtcccacaccagcgctctgccgtctttcaacagccagtgatattcctgggagcggatgttacacaccccccggcaggggatgggaaaaagccttcgatcacagcagtggtaggcagtatggatgcccatcccagccgttactgtgctactgtgcgagtgcagcgaccacggcaggagatcattgaagacttatcctacatggtacgtgagctgcttatccagttctacaagtccacccgcttcaagcctacccgcatcattttctaccgagatggtgttcctgaaggccagctcccccagatcctccactatgagctgctggccattcgtgatgcctgcatcaaactggaaaaggactaccagcctgggatcacttatattgtggttcagaaacgccatcacacccgccttttttgtgctgacaagaatgagcgaattgggaagagtggtaacatcccagctgggaccactgtggacaccaacatcacccacccatttgagtttgacttctatctgtgcagccacgcaggcatccagggcaccagccgaccatcccattactatgtcctttgggatgacaaccgtttcacagcggatgagctccagatcttgacgtaccagctgtgccacacttacgtgcgatgcacacgctccgtctcaatcccagcacctgcctactatgctcgcttggtggctttccgggcacgataccacctagtggacaaggagcatgacagtggagaagggagccacatatcggggcagagcaatgggcgggatccccaggccctggccaaagccgtgcaggttcaccaggatactctgcgcaccatgtacttcgcttgaaggcagaacgctgttacctcactggatagaagaaagctttccaagccccaagagctgtgctgcccaaatccagaggaagcagggaggagggaggtggggtaggaagaaatgcagaaggccttgtttccttctacagagtggatgaaagagtggggaacagggccagtaagccagaccaccagccagaaatctctgatattcacctcatgtcctccacccctcaccccatcttgtcacatctggccctgaccccactggaccaagacgggcagcatcggtgcccaccatacacacaggtgtctcatgtgactcacagtgctaaagactcatgcctgacagcttggtaaggtcggctctgcagccctgcggacaaaagctggtaggtttgggtttgatactttagatgggaaagtgaggggcttgagaaagtgggtgggaggagggaagaatattttaggagccttaatcagaaaaggtctagatttgtttaagaagaaaaacgaaaccagacccagatcaatattttaggatactagatgttttaattggttgataatccagtttgtaggaagatttttaatgctaatggttttggttgctcctcccccagctgtcactcccctttccctattcctctctttccaccttttctaccccgccttacacctcctccctgtcagacaaccagcccctagtaagacttaaggcactatggcacttagctccgaagtgacatgaccctgtcttccttccgcctgctggtgggtaaccagtgccttccctgtaacggtaatgctgcagaactgcaaccttttgtaccttttgggtgggggacggggaggggtgggagaggaggtaggtggggatgaaatacccctaacccaacaagcctccagccagagcgccagctattttgcatttgaaggaattgacttccatattcattgagctttttaaaagatcatgacctcaagatggttaaaatccattgacatttgcactttcagacctgacaagtctcagagctgctgagatgactggcccctggcctttccacttatgtctcctttcttcctgtctcccattcctgggtctggagttactttcatagcatttctcactcttggtttctttttttccctgatggtcaagtctctttacgtttcaatatttcttaactggggtgtcttataacaaacgatccttaggtctaaaataagaaaaaagcaaaaactaaatgttatttttataccataacttgagtctattgccaaaatctggaaatccctcccatgcccaatgagtttacatcccagaaacattgagccatcagaaggaactatatacctgacttgttctttggcctggctagttagggggtggttatctccccagggtggggctcaggctccacccttcctctgtgcagataatatctttttcttgctacaggctccctcttctgcactgccctgcactctttcctgcaaatgcatcttcccttcctctggactgttttctgacactttggctcatcccagatttcagcgtgtcctgtggataggctggggattttgctgctccctattgcttctgtttacacaaatgaatttttcctggtttcccactagggcatgtgagtgggtagcatgggcttttttttttttttttttttttccatctccctgggtagagatggggtttggctgtcttgcagaactggaaaagtagggggttctagcttggtgcctgtgaccttgaagcaaggctccctctttccttgactgttcatttttttcctgtcccactgtttgggatgcggagttcagcttcagtgtggaaattcctctttttgaggaacctgggcttggatttgccctaatctggtgatgaagccatgacactttagacctagcttgtgctcagaggccagccagaggaaggtcggtctgaatacgggcctgtgcagttagagctaccatttcccctccccagcagcccttgtacagacccagatttgctatgcaaaacagtctatcccaggttcttttctggttggctacttcattcagcaacttcacaaaacgtagcacaaacattgattatggagaaggcatcaggactgttgagtaactcctcctttacttcttttgtactggtatgggatgccccatgggcacagcccagctgaagaacagaatggagggctctgggaggaggcagctcactggagagcctacattccttacacaagtgcctaaagagagtgatgccaacactccatctgccctgtccatcgccttcatacactgtctacttcgtgttcagtcaccctttggggaggggagctctcttgggacagtgggctctgcatgttctcttcttgggtgtgttttggggctgggatcagggcagcattcctggaggatccagtcattcaccagcatttgcaaatatccattgggagctggtggtagccacctactctcagcaacgagtttgtgttctctcttttttctctctttgcctcactctctccagttgggttttgaactggggcttgaaatgtgtattttagccctttggcattgtatatgccatttaggaaataaaagcaagaaaaacagcttgggcaatggcaagaaaatgacttcttgctgtgattttctttcttttcttttcttcttttttttaatctttgaaacttgaaaaatgaccttgaggattattcttgtttgaaaggtggtgcatgcagattgagcagtggtgttggcagcaagctttggctttctgggatttggttaaagtggtgcttcttacttaagctttgaggaattgctggggggaccccagcctcatcctcttaaacaggtctcttctccctttctttcacttttttgccttccttttccccttctctcttcctctgatctcttttaattttttattttatttattttttgttgttgttcactcagcttgctggctggcctgtctgcctatgtgataatgaattctctgcatggctacaatgatcccaccgttagctggcaaggtcaggcttagctccttggctgtaggagaccaagaatctgtttcccaggcccagtgatgtccaccctgggctgtactgccctccaacttacatgagggcattagcagaaggcctgtccaactagcatgataccaggagggcttctggcaacttccacacttgtccactctttggagttggtttctctcattgctttttctagatctggtttcatttctctcttcttggggcctcccttttctgaggatgtcctagagttgagctacttggtcatccggagttggagggttaggagatggacataggggaagaagagagtgataggaagaaaatggagagagtgtggcttaaatgtgggaaaggagggcattgatcttattgatcacttttccagtctagcctgactcattgggggttgaggtgctactgctagccactggggataatcctggggctgttgttcctgcgaacttaggcttagaataatgctgaagaagaaggtacctaaaagtatgacacctcccttaaaagttccggttctttcctattcagtagatcctctctggcctcctctttggctaagcaatgatgttgttggatagttttctttttcttgtccagaattctgtaaatgaggctagcaagatggacagccacggagacactttgacttcttagctggcccaggggatatctgcaaggctgactggacaatgtttttagacttggcatcatgtgtaataaagaaggatgaaagttccttccccttcagggtagaaagtcatctcaaactaactaaaatgttgttttggaaactacattggggaagttatttttatttatatttactgggcctaggccaatccaggatggtagctgggatgccttccttcttaaagtctgatcatggcagggttttgcagggcactgtttcctctttggccttctaagcagactggggagaagggattctctggttttctctccctccctccccccaccatttattaggacttaccttctccctgggcagggagagaggctaggttggtgctctccccttactctactccttagaacctctagctgctgtttgggagcccaagaaaggggatggagggaatgagctcaaaagaaaagaaaagaaaacaaaacaaaaaacagaataatgtggggaaggcagatttccttctttaaaaaggaaaataggaaaccctccaaggattgtgcaagtaaagacaatgtgtcgaatgcactgagtcccctggtgtagtagcaataaggaaaaatgaaatgactttcctgtgcacacagtccagcctgattggtgtgtgatgttgcacttagcagccatctggtgggcatgtgtgactactctgggtttcactttagtttctaaactttttatctctctcaagtccagcatggatggggaaatgttccttgaaccccacagctgtgtacttgtttgcatttgtttccccttgagacttgtgtttgtgtcctgctttgagctgtaccttgtccagtccattgtaaaattatcccagcagctgtaatgtacagttccttctgaagcaagcagcagcagcacaattctgtgttttataaagacaacagtggcttctatttctaaagtgcggtctctctcctttttttcttagcaaagaaaattcttgggatgaattatatctctgataggttttagattagaataatagattgatataagagtagaaccatcacttactaaaaggaggacagtgggtaaatcaaattccagagtgttgaaactgcagatcatatgtaatcatatttcatagggcctccacttattcttcattcaacaaacatgcaaagcactgtatcccacagtattgtggggaagtaggcaggcacaattcaaaaatgaggaaaatagctccttaaggagcttaaaaagtttggtgggggatgtgagtggtcatatggttcccaggtaccatttagagagagcgattgagggactgaacaagctgtaagtcagtagcaatgaaatagcaaagggcagacttgatagatgctcaggagatagacttatttggactcagtgaatgatggaacgggaagagagaagtagaggctaatgctcactctgcttgagcaagtaagtgtattgggacagtcctctagccaagattaggggaaaggggaggcaatagaaggaaggtggtgaattttgcgaagaaatacaattaaccttgtatagactcaacttttaggttcccaaggggcaacaaggttaaggtttccagtaaacacaatgttttggtgctcagggaagactacaaaactgcagttatagacatgggattcacattcatataaatggtagttaaagccattggagtgaacaagttggcttagaaaaagagtagagcatgagaaacctagtgtgcaactctaggaaacacagtttaagggatgaggagaggaagcaaaatggaaaatgactgtcagattactggtaaataccttgtatatttttgcttgatttaatgaggtgggagattagtcaagagagtagaataggattcaagaaaaatgttattaacatcatgacaactgattttcaccatgaaaactgaaaagagggtatttttctacgtagtttaccatcctccaccccgtctttgggatcttataactattggtcattctccaatatttcttaaaaatgaacattggaaaaacctaacttaaataacgttaagactgggacttccaagttgttcaccaccacctccacctccagcttccttctatcctcaggagatacttgtaaaagaataaaataaacaaacctaattttgttcctaa
//

by @meso_cacase at DBCLS
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If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596. [Full Text]