LOCUS       XM_003969181            6345 bp    mRNA    linear   VRT 05-JUL-2019
DEFINITION  PREDICTED: Takifugu rubripes argonaute RISC component 4
            (LOC101078091), transcript variant X3, mRNA.
ACCESSION   XM_003969181
VERSION     XM_003969181.3
DBLINK      BioProject: PRJNA543527
KEYWORDS    RefSeq.
SOURCE      Takifugu rubripes (Fugu rubripes)
  ORGANISM  Takifugu rubripes
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Neoteleostei;
            Acanthomorphata; Eupercaria; Tetraodontiformes; Tetradontoidea;
            Tetraodontidae; Takifugu.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_042296.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Jul 5, 2019 this sequence version replaced XM_003969181.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Takifugu rubripes Annotation Release
                                           103
            Annotation Version          :: 103
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.2
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6345
                     /organism="Takifugu rubripes"
                     /mol_type="mRNA"
                     /db_xref="taxon:31033"
                     /chromosome="12"
     gene            1..6345
                     /gene="LOC101078091"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 3 ESTs, 9 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 18 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:101078091"
     CDS             196..2787
                     /gene="LOC101078091"
                     /codon_start=1
                     /product="protein argonaute-4 isoform X3"
                     /protein_id="XP_003969230.1"
                     /db_xref="GeneID:101078091"
                     /translation="

MEALGPGPPAPTSLFQPPRRPGLGTVGKPIRLLANHFQVQIPKIDVYHYEIDIKPEKRPRRVNREVVDTMVRHFKMQIFGDRQPGYDGKKNMYTAHPLPIGRDRVDLEVTLPGEGKDQTFKVSLQWVSVVSLQMLQEALSGHLNEVPEDSVQALDVITRHLPSMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWNMMLNIDVSATAFYRAQPVIEFMCEVLDIQNINEQTKPLTDSQRVKFTKEIRGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLENGQAMECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLVKSNSMVGGPDPYLKEFGIVVHNDMTEVTGRVLPAPMLQYGGRNKTVATPNQGVWDMRGKQFYAGIEIKVWAVACFAPQKQCREDLLKSFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFKHLKMSYVGLQLIVVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINAKLGGINNVLVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDGHPSRYCATVRVQTSRQDMSQEQLFSQEVIQDLTNMVRELLIQFYKSTRFKPTRIIYYRGGVSEGQMKQVAWPELIAIRKACISLEEDYRPGITYIVVQKRHHTRLFCSDKAERVGKSGNVPAGTTVDSTITHPSEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKDHDSAEGSHVSGQSNGRDPQALAKAVQIHYDTQHTMYFA"

     misc_feature    277..666
                     /gene="LOC101078091"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:435368"
     misc_feature    697..849
                     /gene="LOC101078091"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:430160"
     misc_feature    850..1212
                     /gene="LOC101078091"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(1006..1008,1051..1053,1093..1095,1105..1107,
                     1159..1161,1180..1182,1186..1188)
                     /gene="LOC101078091"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1351..2658
                     /gene="LOC101078091"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(1762..1764,1774..1776,1810..1821,1828..1830,
                     1852..1854,1861..1863,1873..1875,1885..1887)
                     /gene="LOC101078091"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(1966..1968,1972..1974,2212..2214,2626..2628)
                     /gene="LOC101078091"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

acaaatcctcagtaggagcaggagcagcagcggtagtttgggtcagtcagtcagtccagtcggcaggcagccacgcaactgtctgtattccttcttcttaaattagccactttaagcttcgagataccgcccccaatttcagcgtcggtacggagccgccaggccgggacagagacggagagcgaggcctcggccatggaagcgctcggacctggccctcctgccccgacctctctgtttcagcctccacgccgtcccggcctcggcacagtgggaaaacccatccggctccttgccaatcacttccaggtgcagattcccaagattgatgtctatcattatgagatcgacatcaagcctgagaaacggcctcggagggtcaacagggaagtggtggacaccatggtgcggcacttcaagatgcagatctttggagaccgacagcctggttatgatgggaagaagaacatgtacacagcacacccactgccaattggaagagacagggtggatctggaggtgactcttcctggggaggggaaagatcagacgttcaaggtgtctctgcagtgggtgtctgtggtcagcctccagatgctgcaggaagctctctcgggtcacctaaacgaggtccctgaagattctgttcaggctctggacgtcatcacacgacacctaccttccatgaggtatactcctgtgggccgctcttttttctcccctccagagggctattaccatcctcttgggggaggcagagaagtgtggtttggtttccatcaatccgtccgtcctgcgatgtggaacatgatgctcaacattgatgtgtcagcaacagccttctaccgtgctcaacctgtgatcgagttcatgtgcgaggtgctggatatacagaatattaatgaacagaccaaaccgctgacagactcccagcgcgtcaaattcaccaaggagataagagggttgaaagtggaggtcacacactgtgggcaaatgaagaggaagtaccgtgtgtgtaatgtaactcgccgacctgccagccatcaaacttttcccttacagcttgaaaatggccaagccatggagtgcactgtagctcagtatttcaagcagaagtacaatctgcagctcaagtatccacatttaccctgtctgcaagtaggacaagaacaaaagcacacgtaccttcccctggaggtctgtaacatcgtagcaggtcagcgctgcatcaagaaactgacagacaaccagacgtccaccatgatcaaagctacagcccgttcagcccccgaccgacaggaggagatcagccgactggtcaaaagtaacagcatggtggggggtccagacccgtacctaaaagagtttggcattgtggtgcacaatgacatgactgaagtgacgggacgtgttctcccagcacccatgctgcagtatgggggccggaacaaaacggtggcaacgcccaaccagggcgtttgggacatgagagggaagcagttctacgctggcatagagatcaaggtctgggctgtggcctgctttgctccacagaaacaatgccgagaggatctactcaagagtttcactgaccagcttcgaaagatctccaaggacgccgggatgccgatccagggtcagccatgtttctgtaaatacgcccagggagccgacagcgtggagcccatgttcaaacacctcaagatgtcctacgttgggctacagctgattgtagtcatcctcccagggaaaacgccagtctatgctgaggtgaagcgagtgggcgacaccctgctgggcatggccacgcagtgtgtgcaggtgaagaacgtagtgaagacgtcccctcagaccctgtccaacctgtgtctgaagatcaatgccaaactgggcggcatcaacaatgtcctggtgccccatcagaggccctcggtgttccagcagcctgtcatcttcctgggggctgatgttactcaccctccagctggtgatggcaagaagccctccatcgcagcagtagtgggcagcatggacggtcaccccagtcgctactgcgccacggttcgggtccagacgtcgaggcaagacatgtcccaggagcagctcttcagccaggaggtcattcaagatctgaccaacatggtgcgggagctgctcattcagttctacaagtccacccgctttaagcccacacggatcatctattaccgcggtggagtgtcggaggggcaaatgaagcaggttgcttggccagagctaatagccatcaggaaggcctgcatcagtctggaggaggactaccggccgggcatcacctacatcgtggttcagaaacgtcaccacacgcgtctcttctgttctgacaaagccgagagggttgggaagagtggaaatgttccagcaggcaccacagtcgacagcaccatcacacacccgtccgagtttgacttctacttgtgcagccatgcagggattcagggaaccagtcgtccctcccactaccacgtcctttgggatgacaactgtttcaccgccgatgagctgcagctcctcacctaccagctgtgccacacttacgtccgctgcactcgctccgtctccatcccggcgccggcgtactacgccaggctggtggctttccgagcacgctaccacctggtggacaaagatcacgacagtgctgaaggcagccacgtgtctggtcagagcaacggccgtgacccccaggctttagccaaggcggttcagatccactatgatactcagcacaccatgtacttcgcctgaactagtgagcacatcgacgatccacccgcagctcctcctcctttctttttctttttcaagtctgttgccagtctctctgcttgtagtctctttacacttgatcttattttctaaatctgcacccgagcggcactcggatggtggggaaacctgctgtctcctgatgtccagcaggtttttgtattaaggaacaaccaaccaaccagcgttcccactcgagctgcctttcaaaccagcaatccagtgctgtgacaccagcgaggtgtttccagtacacaaaagaagaaagaaaaaaccaagttgagccattattttccttattttctatttgaatgtctgcactcttgtgttgtaagatacactgagcgagggagtgatgtgacacggtgtgtcagcacagctctttagctctcccagctaagcaggactcttatctacttttacctcaaagcccgtttgggcaaaatctgtcacaaggtctcgggtttattgggtggtggggagggaactctaccagaacagagatggaggggcatcgaccttttgagaatgagagagagatatatatctatatacatatattttttccttttaatgagtgtgttttaccttttctcctttgccgtcttttacaattaaggtgacctggttgtcatgcccacgactactttccttcaacgttggtgatgaaaatgtagtctgtgtgtgagaatgtgtctatttgtatatacatgtactgctgtaagagtgtgtgtgtgtgtgtgtgtgtgtgtgtttcatggcaggccactgaattgtaaagggaaatcacggggataactgctgtaaatgcctcagatttgttttttatatccactcatacagtacatataagcatatatttacatctataaaacaactttgagacgtatgacttaaacaggcctcctgaagaccagcgtgtgggtatttgtagctttcctgggtcacttaataaacatttggtttgaattgggtttgaatcgttggctggcctgctgctggagccggatgggacgtgcaccttcggtagggggtggctttgttcgtgcctggtaacatctttgaatccccagaaacaaaagtgatggaagcattttcggtgggaggtgcagtcatgtctgatatgtagcattagtaaccagtttgggccctgactggctcagctttggggcccgttgattggctgaaggcattaaaccgtacggttgcgccacctctgtgcatgaaaggcaggatgttgtttttctttggacctgattatcagagagtttttgtacagttactcggctgcgtttatttttttttttgcagggccagaaaccagtaagcttttttcttttcccctctcccatcttaataattcattgcactgacccgggatgcaggcgagcaacagagggcactctcaatctcttgtacctttatgcatttatacatacgaatcaacaagtcagatttgtaaaagtttaatataagatgttttgtggctatattaaaagctgtcgtttagaaatagtttaccgttgttgttgtttattgttgtcaatgttgttactattgtgatgaaattttacagttggcagcaacgccagttttatattttctagtttgacttcaggaatagttgttgggctgcaggtcgaaggcttcggagctttggagcagatatattttgtagcattttggttaatgtgagatgtagaccccagctaggaggagttcacgcctcctccgacagcttcaaggccactaaaccttagcgggagactctgggtgtttggtggcagctttgatcggatggaaacaatcggggatcgtaatcggaccgaagctgagatcgaggattggtcaaaggtggtcagtgacgtaaaatgagctgaatttttactctttgaaatggtttctatcgctgtatttgaggttatcccatgatgaaattgatgtttttagatttttgacactggatgtagaggtaaacgccctttgaaccgcagtgacacccagtaatgtgcactggtggcggaaatggcgccccctggtgttgcggagatgagaagcagtcgacgtgcacgcctcgtcaggggggcagctcagtggaagcctttttgtaataaaccgcccgtaaagcagcaggtttactatgaaatggtgtgagcgcctgcctgttgaaggcgtgggcgttggcagggttcaggaccgttttttgaaggagggggtgcgctgtgatttgcgggcattgtccaggttttgcatgcaataatttttttggttaaaggagcagatgtttttaaaatgtgcactagttttaccaagccaatgcgggtgtaattggaaagtcacccggcttctaaagggtgaacgttttctaccttccacactgtttgaactccactcggatcagccatcactccccgtttgacaaggttgcagagcaatatgaccccagttctagatttcagatgtggaaatacaaatctcatcatggttgtctactcttgcaattgtgttgtgtgtactcttcctttactttgttctttttagttgatatcatttgcttgtatcaatcagtgggaatgtgcatttggtggaatagatgtataggctctagacaatttccttttaaagtaacaaagtgtagactttgctcacctgcatgccagagtattgtccttttttttaaaaaaaaaaaaaaagaaaaaactttagaaacatatttatcaaagagaagaaagtataaatgcttctttttggggtaaatgttgaatttagtaggactattttaggctagcaatatttgtccagatgcattttaaagattcctacacaaatgtcagtaattctccaagtacactgttattgaggcgaggtgactccgctcttttctgggcgttcacattcaaaacgaggtacctttcttcaaacgtggagcccttcaagagctgactcgcctcgcctttgccaggtttcaacggcgagcatccatttttgtctccttgttcctggttttgtacccacagccacacctcttgatgagggaggcctttgtctcggtggcccctctgctgacctctcacaaatgcacttcctctttgtgtaggggtcccctgtgacatcagcagagcacgcttacctctttctacacctttttatttttttttttaaatgaaaagtccctaattgtttctgtgccccaagtgaatgaaagcatgaattcttttgaaattcctcttcctttgatatattgttatatcttaacagatttgtaattgtgtgttacatatttttagtttcattttgtggttccttttcaggggtttcttaaaactgttttcccccccactagtggtctctgatgcttttgtgactgttttaatggtaacaacaggttctgggggaagggggtgggcatgcccagcccctgttattgctattatgccacatgttcacgtatattttattttttttattttatttttttttagcctgcagggaattcttgtgttaatgtgcaaagtaataaattggtattttaagcct

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