LOCUS       XM_002049304            6087 bp    mRNA    linear   INV 11-FEB-2020
DEFINITION  PREDICTED: Drosophila virilis protein argonaute-2 (LOC6624789),
            transcript variant X1, mRNA.
ACCESSION   XM_002049304
VERSION     XM_002049304.3
DBLINK      BioProject: PRJNA501994
KEYWORDS    RefSeq.
SOURCE      Drosophila virilis
  ORGANISM  Drosophila virilis
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Diptera; Brachycera;
            Muscomorpha; Ephydroidea; Drosophilidae; Drosophila.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_022587570.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Feb 11, 2020 this sequence version replaced XM_002049304.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI
            Annotation Status           :: Full annotation
            Annotation Name             :: Drosophila virilis Annotation
                                           Release 103
            Annotation Version          :: 103
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 8.3
            Annotation Method           :: Best-placed RefSeq; Gnomon
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6087
                     /organism="Drosophila virilis"
                     /mol_type="mRNA"
                     /strain="15010-1051.48,49,85"
                     /db_xref="taxon:7244"
                     /chromosome="Unknown"
                     /tissue_type="whole body"
                     /dev_stage="adult"
     gene            1..6087
                     /gene="LOC6624789"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 1 EST, 64 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 48 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:6624789"
     CDS             347..3316
                     /gene="LOC6624789"
                     /codon_start=1
                     /product="protein argonaute-2 isoform X1"
                     /protein_id="XP_002049340.1"
                     /db_xref="GeneID:6624789"
                     /translation="

MSTERELAGGPAQLHTLPLTFSPDLGTALQLNSAVGIMGKVYESQWTTPSPTRPQSPSQAQTSFDTLTSPPAPGSSVNPTAVTSPSAQNVAAGGATVGGAAAAAAAQVASALGSTASVSAAIAAAAASPTTQPDMPVFTCPRRPNLGREGRPIVLRANHFQVTMPRGFVHHYDINIQPDKCPRKVNREIIETMVHAYSKIFGVLKPVFDGRNNLYTRDPLPIGNERLELEVTLPGEGKDRIFRVTIKWQAQVSLFNLEEALEGRTRQIPYDAILALDVVMRHLPSMTYTPVGRSFFSSPDGYYHPLGGGREVWFGFHQSVRPSQWKMMLNIDVSATAFYKAQPVIDFMCEVLDIRDINEQRKPLTDSQRVKFTKEIKGLKIEITHCGQMRRKYRVCNVTRRPAQMQSFPLQLENGQTVECTVAKYFLDKYRMKLRYPHLPCLQVGQEHKHTYLPLEVCNIVAGQRCIKKLTDMQTSTMIKATARSAPDREREINNLVKRADFNNDSYVQEFGLTISNSMMEVRGRVLPPPKLQYGGRVSSGITGQQLLPPQNKVSLASPNQGVWDMRGKQFFTGVEIRIWAIACFAPQRTVREDALRNFTLQLQKISNDAGMPIIGQPCFCKYATGPDQVEPMFRYLKITFPGLQLVVVVLPGKTPVYAEVKRVGDTVLGMATQCVQAKNVNKTSPQTLSNLCLKINVKLGGINSILVPSIRPKVFNEPVIFLGADVTHPPAGDNKKPSIAAVVGSMDAHPSRYAATVRVQQHRQEIIQELSSMVRELLIMFYKSTGGYKPHRIILYRDGVSEGQFPHVLQHELTAIREACIKLEPEYRPGITFIVVQKRHHTRLFCAEKREQSGKSGNIPAGTTVDVGITHPTEFDFYLCSHQGIQGTSRPSHYHVLWDDNHFDSDELQCLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVEKEHDSGEGSHQSGSSEDRTPGAMARAITVHADTKKVMYFA"

     misc_feature    797..1186
                     /gene="LOC6624789"
                     /note="N-terminal domain of argonaute; Region: ArgoN;
                     pfam16486"
                     /db_xref="CDD:435368"
     misc_feature    1214..1366
                     /gene="LOC6624789"
                     /note="Argonaute linker 1 domain; Region: ArgoL1;
                     pfam08699"
                     /db_xref="CDD:430160"
     misc_feature    1367..1729
                     /gene="LOC6624789"
                     /note="PAZ domain, argonaute_like subfamily. Argonaute is
                     part of the RNA-induced silencing complex (RISC), and is
                     an endonuclease that plays a key role in the RNA
                     interference pathway. The PAZ domain has been named after
                     the proteins Piwi,Argonaut, and Zwille; Region:
                     PAZ_argonaute_like; cd02846"
                     /db_xref="CDD:239212"
     misc_feature    order(1523..1525,1568..1570,1610..1612,1622..1624,
                     1676..1678,1697..1699,1703..1705)
                     /gene="LOC6624789"
                     /note="nucleic acid-binding interface [nucleotide
                     binding]; other site"
                     /db_xref="CDD:239212"
     misc_feature    1865..3187
                     /gene="LOC6624789"
                     /note="PIWI domain, Argonaute-like subfamily. Argonaute is
                     the central component of the RNA-induced silencing complex
                     (RISC) and related complexes. The PIWI domain is the
                     C-terminal portion of Argonaute and consists of two
                     subdomains, one of which provides the...; Region:
                     Piwi_ago-like; cd04657"
                     /db_xref="CDD:240015"
     misc_feature    order(2318..2320,2330..2332,2366..2377,2384..2386,
                     2408..2410,2417..2419,2429..2431,2441..2443)
                     /gene="LOC6624789"
                     /note="5' RNA guide strand anchoring site [active]"
                     /db_xref="CDD:240015"
     misc_feature    order(2522..2524,2528..2530,2741..2743,3155..3157)
                     /gene="LOC6624789"
                     /note="active site"
                     /db_xref="CDD:240015"
ORIGIN      

atacagcaacaacaaataaaacggggcaattaaaagaattaacaattatacaaatagcaacagccaacggccgttagtgaagttcacaacccaaacggagcgcaaataatcaaaactcttttttaatgtgtaacaaatttggaaaaatcactcaacgaacaccaacagcaacaggaaatcgaaaaaaatcgccaacaacgataaaacaacaaattgaacagccgcgaacgacttgtcgctgataggcaaatccataaagcgccgcatcagctgcaattgtgcgataagctgtctctgtcagtggcaatagaagcaacgcctcaagctgacgccgacaccgactaaaatgtcaacggagcgggagctggccggcgggccagctcagctccatacgctgccgttgacattttcacccgatttgggcactgcgctgcagctgaactctgcggtgggcattatgggcaaggtttatgagtcacagtggaccaccccctcgcccacgcggcctcagagcccctctcaggcgcagactagcttcgacacgctcacatcaccaccagcgcccggttcatcggtaaatcccaccgctgtgaccagtccgagtgctcagaatgttgctgccggcggtgccaccgttggtggtgcagctgctgcagccgctgctcaggttgcgtctgctcttggctccacggccagcgtatcggcagccattgccgctgcagcggcatcgcccactacgcagccggatatgccggtattcacgtgcccgcgacgaccgaatctgggccgggagggcagaccaattgtgctccgtgcgaatcactttcaggtgacaatgccgcgtggttttgtgcaccattacgacatcaatatacagccggacaagtgtccgcgcaaggtgaatcgcgagatcattgagaccatggtgcatgcgtatagcaagatctttggggtgctcaagcccgtgtttgatggacgcaataatttgtatactcgcgatccgctgcccattggcaatgagcgtctggagctggaggtgacgctgcccggcgagggcaaggatcgcatcttccgtgtgacgatcaaatggcaggcgcaggtgtccctttttaatctggaggaggcgctcgaggggcgtactcgccaaataccctacgatgccatattggcactcgatgtggtcatgcgtcacttgcccagcatgacgtacacgcccgtgggacgcagtttctttagctcacccgatggctattatcatcctctgggtggcggtcgtgaggtctggtttggtttccatcagagcgtacggccatcgcagtggaaaatgatgctcaacattgatgtttcggctaccgccttctacaaggcacaaccggtcattgattttatgtgcgaggtcctggacatacgcgacatcaatgagcagcgcaaaccgctcaccgattcgcagcgcgtcaagttcaccaaggagatcaagggactcaagattgagattacgcactgtggccaaatgcgtcgcaaatatcgcgtctgcaacgttacacggcgaccagctcaaatgcaatccttcccgctgcagctagaaaacgggcagactgtggagtgcaccgtggccaagtactttttggataagtatcgcatgaagctgcgctatccgcatttgccctgcctgcaggtgggtcaggagcacaagcacacctacctcccgctcgaggtgtgcaacatagtggccggccagcgttgcatcaagaagctcaccgatatgcagacatcaacaatgatcaaggccaccgcacgctcggcaccagatcgcgaacgcgagattaacaatctggtcaagcgtgctgacttcaacaatgactcgtatgtccaggagttcggtctgaccatctccaattctatgatggaagtgcgcggccgagtgttaccgccaccaaagctacaatatgggggacgtgtctcgtcgggcataaccggacagcagctgttgccgccacagaacaaggtcagcctggcgtcgcccaatcagggcgtttgggatatgcgtggcaagcagttcttcacgggcgtcgagatacgcatttgggcaattgcctgctttgcgccacagcgcacagtgcgcgaggatgcgttgcgtaactttacactgcaactgcaaaagatctccaatgatgctggaatgcccatcattgggcaaccttgcttctgcaagtatgctactggaccggatcaggtggagcccatgtttcgttatctgaagataaccttccccgggctgcagcttgtcgttgtcgtgctgccgggtaaaacgcccgtctatgcggaggtgaagcgtgtgggcgacacggtgctgggcatggccacgcagtgtgtgcaggccaagaatgtgaacaagacatcgccacagacgctctccaatctgtgcctcaagatcaatgttaagctgggtggcattaactccattttggtgccctcgatacgacccaaggtcttcaatgagcccgtcattttcctgggcgccgatgtcacccatccgccggctggtgacaacaagaagccatccatagccgctgttgttggctcgatggatgcgcatccgtcgcgttatgcggccacggtgcgcgttcagcagcatcgccaggagataatacaggagctaagcagcatggtgcgcgaactgcttatcatgttctacaaatccaccggtggctataagccgcatcgcatcatactctatcgcgacggcgtctccgagggtcaattcccccatgtgctgcagcacgagctgaccgccatacgcgaggcatgcatcaaattggagccagagtaccgaccgggcatcacatttattgtcgtacagaagcgtcatcatacgcgactcttctgcgccgagaagagggagcagagtggcaaatcgggcaacatacccgccggcaccaccgtcgacgttggcatcacacatcccacggagtttgatttctatttgtgcagccatcagggcattcagggcaccagtcgcccctcccactatcatgtactctgggatgataatcactttgattccgatgagctgcaatgcctcacctatcaactgtgccacacctatgtgcgctgcacgcgctctgtcagcatcccagcgccggcctactatgcgcatttggttgccttccgtgccagatatcatctggtcgaaaaggagcacgattccggcgagggatcgcatcagagcggctcctccgaggatcgcacgcccggagccatggcacgcgctataacggttcatgccgataccaaaaaggtcatgtactttgcctaaaaagtataaaaagcgacaccaaaatgaaaaacaaacaaattaacaaaaacacatccacacagcagcagcagcaacaacaacaacaaaaacacttaaatttcgaaaatgaattcgaataagcagccaactcagaaaaaaaagaagcaaagcgtttacaaaagccgagtcgaaatcattagagaataagtttaaaatgatgtttatatttaagttacaaagaaagccagaacagctcttatggagcacatttgcattagcttttaggcccaaaatacacacacacaccaatacccacacgccaaaaccgtagggattagagaaaaagggaatcgaatgtttaagcacaagcaggcgcaacaaatgtgaaagagaattctcaaaaaaaaaaaaaatttttaaaataaaaacaagcgtagcgaaacaaactaaagggaacaaaacgaaagtcaaataacaacaacaaaaacaacaacagctgaaaacaaacgcaaaaaaaaacaacaacacacatttacgatgaacttttgtaatagaataaattatatttttacacaatacaaaacaaaaacaaagtttaaaaaatgtgaagacaaaaaaaatgcagacaaccaaaggttttttagtatatcaaaacaagaaaaaagttgctgattaacacacacacacacacagacacagacaacaaaacacatacacaaaaacaacaacaagaacaacaactcggaattctctgtactgtgaacgaagaccaccaccaagcttaaagaattattaacaaaaacaaaaatgacaacaacaaacaacaacattacgacaagcattaaagagtgtaataattagccatatatatctatatatatatatatatgtatgtatgtataaaacaaaaagaataacttcaatactactacaactcaaatgtccagaattgtaaagaaaagcaaactttttagtagacttaagttgggaattaccaaaaaaaaaaaaaaaaaaaaaacaaaacaaaaacaaaaaagtaacaacattaacgataactccaatttcaacaagggacaaacttttggtcaaacaattgctagttatatttatatattataatataaatataaagatatacatatatgtgtatttaggcaacaagtatattgtatctgtataaacgtggctagccgtgactttaacacaaatggcataaaacaaaaacaatacttaaaagtttgcgctaaacttatgttaaagtcaacagttgctgtttaactaaacagcgaatttaagttataaataaatagtttatgttttctataaacacactatgcacacacacacacactcacacacacacaacacaacatacacggcatatcaaacccaatgtccaattaatttatgtacctctatttagctcaacttaggtttcataattttaataacaaacacaaaacgctgttaattgtattaatgaagtcttaacaaataacgtggtgtacgggtaaacaaataatatgataattaagcgcaattcttaattcaaattatattttcgcagctgctccccttaactcatagggcatatttagtttaagttttagttttttttgttttttaaataattgccaattttacaaaccttacaaatattaatatgtatacataaatttatatacatatatgtacttttatggaggacacagttcaagttaacattatgctgatttgttcttattatagaaccgaaaacgagcaacccatttatttataacaattgctgtcttcagacacttcaagcgccgccctctcatgcaaatatgttgaagtttaattaacaattgttttaaaaaatatatttcgatgcctttcaaaacatgtcgtctacacacacgcacacacacagtcacacacaaatgcctacaccctcacacacacacacatacataaaatacatatatgtgagcattataaaatacataaattataaacgtgttaagctaatattttctattacaaattagttcttaaaacgaaaacaacaaaatgaaagtgtgcaaaagcagctgaagattcggtagctttgtaacatgtttattttgttttaaatgtatttgtattttttatgatgaaaaacaaaaacaaaaaaaaaaacattaattatttagcatgttttaacacaagggattaaaattgtacatttatttctaaacaaacaaacaaagaaaaacaaaaaacaaacgagtaaaaaaacaattctaattttaaggacatccaaaagcaaaaaagcaaaaagcaacaatgtaatcgaaacaatgcaaaaatgatgcggggtctcttaagtttaggtacatgcgcccgggtctctcaacaaaaccccactctacaaatacatttttacgtactttaagcaaaacaacaacaacaatttatgtgccgacaatgaatgtatccttgtaattgtaatttgtacttgtaaaacacacgaggcatagctataatgctggttcgacatttatagagcaaagtctaaagctttaacacaaaatacatgataaacataaacataaatatatatctatatatatatatatatgtgtatatatatctagatgtatgcccagactcttgaaacaacagttgacacttgtgattaagacagaattaatatgggcgcataacttataaatcacataatccattacatatatatatatatgtatatatatatatatacgtacatatataacaagctaatctaattgcaataaaagatttatacataa

//