LOCUS       NR_189741               3536 bp    RNA     linear   PRI 28-DEC-2023
DEFINITION  Homo sapiens EF-hand calcium binding domain 13 (EFCAB13),
            transcript variant B, non-coding, non-coding RNA.
ACCESSION   NR_189741
VERSION     NR_189741.1
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3536)
  AUTHORS   Willer CJ, Schmidt EM, Sengupta S, Peloso GM, Gustafsson S, Kanoni
            S, Ganna A, Chen J, Buchkovich ML, Mora S, Beckmann JS,
            Bragg-Gresham JL, Chang HY, Demirkan A, Den Hertog HM, Do R,
            Donnelly LA, Ehret GB, Esko T, Feitosa MF, Ferreira T, Fischer K,
            Fontanillas P, Fraser RM, Freitag DF, Gurdasani D, Heikkila K,
            Hypponen E, Isaacs A, Jackson AU, Johansson A, Johnson T, Kaakinen
            M, Kettunen J, Kleber ME, Li X, Luan J, Lyytikainen LP, Magnusson
            PKE, Mangino M, Mihailov E, Montasser ME, Muller-Nurasyid M, Nolte
            IM, O'Connell JR, Palmer CD, Perola M, Petersen AK, Sanna S, Saxena
            R, Service SK, Shah S, Shungin D, Sidore C, Song C, Strawbridge RJ,
            Surakka I, Tanaka T, Teslovich TM, Thorleifsson G, Van den Herik
            EG, Voight BF, Volcik KA, Waite LL, Wong A, Wu Y, Zhang W, Absher
            D, Asiki G, Barroso I, Been LF, Bolton JL, Bonnycastle LL,
            Brambilla P, Burnett MS, Cesana G, Dimitriou M, Doney ASF, Doring
            A, Elliott P, Epstein SE, Ingi Eyjolfsson G, Gigante B, Goodarzi
            MO, Grallert H, Gravito ML, Groves CJ, Hallmans G, Hartikainen AL,
            Hayward C, Hernandez D, Hicks AA, Holm H, Hung YJ, Illig T, Jones
            MR, Kaleebu P, Kastelein JJP, Khaw KT, Kim E, Klopp N, Komulainen
            P, Kumari M, Langenberg C, Lehtimaki T, Lin SY, Lindstrom J, Loos
            RJF, Mach F, McArdle WL, Meisinger C, Mitchell BD, Muller G,
            Nagaraja R, Narisu N, Nieminen TVM, Nsubuga RN, Olafsson I, Ong KK,
            Palotie A, Papamarkou T, Pomilla C, Pouta A, Rader DJ, Reilly MP,
            Ridker PM, Rivadeneira F, Rudan I, Ruokonen A, Samani N, Scharnagl
            H, Seeley J, Silander K, Stancakova A, Stirrups K, Swift AJ, Tiret
            L, Uitterlinden AG, van Pelt LJ, Vedantam S, Wainwright N, Wijmenga
            C, Wild SH, Willemsen G, Wilsgaard T, Wilson JF, Young EH, Zhao JH,
            Adair LS, Arveiler D, Assimes TL, Bandinelli S, Bennett F, Bochud
            M, Boehm BO, Boomsma DI, Borecki IB, Bornstein SR, Bovet P, Burnier
            M, Campbell H, Chakravarti A, Chambers JC, Chen YI, Collins FS,
            Cooper RS, Danesh J, Dedoussis G, de Faire U, Feranil AB, Ferrieres
            J, Ferrucci L, Freimer NB, Gieger C, Groop LC, Gudnason V,
            Gyllensten U, Hamsten A, Harris TB, Hingorani A, Hirschhorn JN,
            Hofman A, Hovingh GK, Hsiung CA, Humphries SE, Hunt SC, Hveem K,
            Iribarren C, Jarvelin MR, Jula A, Kahonen M, Kaprio J, Kesaniemi A,
            Kivimaki M, Kooner JS, Koudstaal PJ, Krauss RM, Kuh D, Kuusisto J,
            Kyvik KO, Laakso M, Lakka TA, Lind L, Lindgren CM, Martin NG, Marz
            W, McCarthy MI, McKenzie CA, Meneton P, Metspalu A, Moilanen L,
            Morris AD, Munroe PB, Njolstad I, Pedersen NL, Power C, Pramstaller
            PP, Price JF, Psaty BM, Quertermous T, Rauramaa R, Saleheen D,
            Salomaa V, Sanghera DK, Saramies J, Schwarz PEH, Sheu WH, Shuldiner
            AR, Siegbahn A, Spector TD, Stefansson K, Strachan DP, Tayo BO,
            Tremoli E, Tuomilehto J, Uusitupa M, van Duijn CM, Vollenweider P,
            Wallentin L, Wareham NJ, Whitfield JB, Wolffenbuttel BHR, Ordovas
            JM, Boerwinkle E, Palmer CNA, Thorsteinsdottir U, Chasman DI,
            Rotter JI, Franks PW, Ripatti S, Cupples LA, Sandhu MS, Rich SS,
            Boehnke M, Deloukas P, Kathiresan S, Mohlke KL, Ingelsson E and
            Abecasis GR.
  CONSRTM   Global Lipids Genetics Consortium
  TITLE     Discovery and refinement of loci associated with lipid levels
  JOURNAL   Nat Genet 45 (11), 1274-1283 (2013)
   PUBMED   24097068
REFERENCE   2  (bases 1 to 3536)
  AUTHORS   Teslovich TM, Musunuru K, Smith AV, Edmondson AC, Stylianou IM,
            Koseki M, Pirruccello JP, Ripatti S, Chasman DI, Willer CJ,
            Johansen CT, Fouchier SW, Isaacs A, Peloso GM, Barbalic M, Ricketts
            SL, Bis JC, Aulchenko YS, Thorleifsson G, Feitosa MF, Chambers J,
            Orho-Melander M, Melander O, Johnson T, Li X, Guo X, Li M, Shin Cho
            Y, Jin Go M, Jin Kim Y, Lee JY, Park T, Kim K, Sim X, Twee-Hee Ong
            R, Croteau-Chonka DC, Lange LA, Smith JD, Song K, Hua Zhao J, Yuan
            X, Luan J, Lamina C, Ziegler A, Zhang W, Zee RY, Wright AF,
            Witteman JC, Wilson JF, Willemsen G, Wichmann HE, Whitfield JB,
            Waterworth DM, Wareham NJ, Waeber G, Vollenweider P, Voight BF,
            Vitart V, Uitterlinden AG, Uda M, Tuomilehto J, Thompson JR, Tanaka
            T, Surakka I, Stringham HM, Spector TD, Soranzo N, Smit JH,
            Sinisalo J, Silander K, Sijbrands EJ, Scuteri A, Scott J,
            Schlessinger D, Sanna S, Salomaa V, Saharinen J, Sabatti C,
            Ruokonen A, Rudan I, Rose LM, Roberts R, Rieder M, Psaty BM,
            Pramstaller PP, Pichler I, Perola M, Penninx BW, Pedersen NL,
            Pattaro C, Parker AN, Pare G, Oostra BA, O'Donnell CJ, Nieminen MS,
            Nickerson DA, Montgomery GW, Meitinger T, McPherson R, McCarthy MI,
            McArdle W, Masson D, Martin NG, Marroni F, Mangino M, Magnusson PK,
            Lucas G, Luben R, Loos RJ, Lokki ML, Lettre G, Langenberg C, Launer
            LJ, Lakatta EG, Laaksonen R, Kyvik KO, Kronenberg F, Konig IR, Khaw
            KT, Kaprio J, Kaplan LM, Johansson A, Jarvelin MR, Janssens AC,
            Ingelsson E, Igl W, Kees Hovingh G, Hottenga JJ, Hofman A, Hicks
            AA, Hengstenberg C, Heid IM, Hayward C, Havulinna AS, Hastie ND,
            Harris TB, Haritunians T, Hall AS, Gyllensten U, Guiducci C, Groop
            LC, Gonzalez E, Gieger C, Freimer NB, Ferrucci L, Erdmann J,
            Elliott P, Ejebe KG, Doring A, Dominiczak AF, Demissie S, Deloukas
            P, de Geus EJ, de Faire U, Crawford G, Collins FS, Chen YD,
            Caulfield MJ, Campbell H, Burtt NP, Bonnycastle LL, Boomsma DI,
            Boekholdt SM, Bergman RN, Barroso I, Bandinelli S, Ballantyne CM,
            Assimes TL, Quertermous T, Altshuler D, Seielstad M, Wong TY, Tai
            ES, Feranil AB, Kuzawa CW, Adair LS, Taylor HA Jr, Borecki IB,
            Gabriel SB, Wilson JG, Holm H, Thorsteinsdottir U, Gudnason V,
            Krauss RM, Mohlke KL, Ordovas JM, Munroe PB, Kooner JS, Tall AR,
            Hegele RA, Kastelein JJ, Schadt EE, Rotter JI, Boerwinkle E,
            Strachan DP, Mooser V, Stefansson K, Reilly MP, Samani NJ,
            Schunkert H, Cupples LA, Sandhu MS, Ridker PM, Rader DJ, van Duijn
            CM, Peltonen L, Abecasis GR, Boehnke M and Kathiresan S.
  TITLE     Biological, clinical and population relevance of 95 loci for blood
            lipids
  JOURNAL   Nature 466 (7307), 707-713 (2010)
   PUBMED   20686565
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CP068261.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC037876.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1966682, SAMEA1968968
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-120               CP068261.2         48186334-48186453
            121-190             CP068261.2         48186833-48186902
            191-352             CP068261.2         48188879-48189040
            353-467             CP068261.2         48190922-48191036
            468-628             CP068261.2         48197849-48198009
            629-740             CP068261.2         48204570-48204681
            741-871             CP068261.2         48206811-48206941
            872-954             CP068261.2         48207665-48207747
            955-1026            CP068261.2         48233087-48233158
            1027-1521           CP068261.2         48237121-48237615
            1522-1659           CP068261.2         48240415-48240552
            1660-1731           CP068261.2         48241831-48241902
            1732-1875           CP068261.2         48254090-48254233
            1876-1950           CP068261.2         48256666-48256740
            1951-2094           CP068261.2         48258475-48258618
            2095-2166           CP068261.2         48264773-48264844
            2167-2310           CP068261.2         48266519-48266662
            2311-2382           CP068261.2         48267203-48267274
            2383-2427           CP068261.2         48272288-48272332
            2428-2571           CP068261.2         48275414-48275557
            2572-2643           CP068261.2         48277490-48277561
            2644-3536           CP068261.2         48292473-48293365
FEATURES             Location/Qualifiers
     source          1..3536
                     /organism="Homo sapiens"
                     /mol_type="transcribed RNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q21.32"
     gene            1..3536
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /note="EF-hand calcium binding domain 13"
                     /db_xref="GeneID:124989"
                     /db_xref="HGNC:HGNC:26864"
     misc_RNA        1..3536
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /product="EF-hand calcium binding domain 13, transcript
                     variant B, non-coding"
                     /db_xref="GeneID:124989"
                     /db_xref="HGNC:HGNC:26864"
     exon            1..120
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            121..190
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            191..352
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            353..467
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    438..1448
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="COORDINATES:
                     alignment:Blast2seq::RefSeq|NM_001426587.1"
                     /note="primary ORF has stop codon >50 nucleotides from the
                     terminal splice site; nonsense-mediated decay (NMD)
                     candidate"
     exon            468..628
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            629..740
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            741..871
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            872..954
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            955..1026
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            1027..1521
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            1522..1659
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            1660..1731
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            1732..1875
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            1876..1950
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            1951..2094
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            2095..2166
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            2167..2310
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            2311..2382
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            2383..2427
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            2428..2571
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            2572..2643
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     exon            2644..3536
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3508..3513
                     /regulatory_class="polyA_signal_sequence"
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /note="hexamer: AATAAA"
     polyA_site      3536
                     /gene="EFCAB13"
                     /gene_synonym="C17orf57"
                     /note="major polyA site"
ORIGIN      

gcggcgcgggatcctgggaaggctgcagagctagagcagcgccgcccgaggggcggcaggggctgaccacagagagcgcgggggcctccagccgagaggaagggagggcagctcgggccgaagtcgttggcttcgtaagagcagggtctatgggaagcctcctcagcgtgggttcttggaagaggtggagtttggagaggcttatgcggtacctgattcatccagcaaattaagacctgccaactttttgataatctcgtcaataaattacagaacaattgttcctttcaagatttattcaaaacgtgtcaactctgcttaattaagcactttgatgatttaagaaatcttggaaatccttttgtactattgctcattcatacttgttcatcaaagcctggagtccttaaggacagaatttacctctaaacagaaagatggaaactaaagtacatttattctgccaggcagaggaaaatattgacttattagatgatggctctaattcttttgcaactgacttgtcatcaggaactattaaccacaagaaatacatcaagttttctaaaacaatagagaaggaaatttcaccggaaattaggagtttgagcccagaatataaaaaaatatttgaaacatcaataatcttttgtggagaagaaaagtcctctgatttttcaggagaaaaaaaagttgggagaaagagtttacaagtacaacagcacagtaaaagaactgagattatccctccttttctgaagctgtcaaaggagaaggtgacaaggaaagaaaactctttatgcaagttgccgaatcagtacagcgttcacaagacttcatcacctctttgtacatcttctgcaattactcgggaaaaggaaatgctgtctaacctctacatgacattatatgatgaagtaacccatggatatttacactcaaaagaattaagtggtaaccacatggtggatattggggatattatatttactttgaatgagctacaggaacagtatgaggatgtttcaattacagaaggatcacctttgaatgaaattacttcagacagaaagttatcaagtatagcaggatgctatctaaaatataagaagaaaaatagtttgtcttccaaactccctgaaccttcaatatccaaaaagttaaataaaaaaagcaaccaatattatagcaaaattatggagaatgatgaccttgaatctaaaagaccaaaaaatacttggcaaataagaaaatttctgggtggggttggcagcagtaatgtaggagtccaagaaccatattcaaagaatggcataaactttaaaaaacattcagagaagggtgaaattcatgactcaaagtctaaaccacaaagcttgaagagtagtacaagcctcagtaagtctctggataaaagtgatatttctagtatcccaaaacttcagtagccagctgtaagaaagcattccagtctccaaaaacaggtttcgtctacggaaaaaactgcaattagtactctggaaaacttctgtgaagctatcagtaaacttcaagaaaattacattgcagcagaagaacttcagtctattttgccttcaacaggaattaatttattagatgaagaattccagaagattgtgacagacactagtagaaatgagaatggaatggtggagttagatgactttgtaaatgctctcgccaaggagcgaagttttcctgaatgcaatgcgttgcctggtgtcattaaagccattgataaaattaaagataaaaatgtggattatgaggatctaaatacttgtcttcaaaattttggtatttacctttctaagccagaatttaagaagatcacagaactgactgaagctggtgaaacaaaaaaagtgaattttaaagaattcattgatactatgatgagcaacacggaatgcttctctgaaaaattagtattgcctgatgctattgaaaccctcgacgatctcagaaaggagacgatgagtgtttctgacctgtggaatactctgtctagtttgaatagtaatttaaaaaaggatgaatttctagctgcattggaactagtgacagttgatgaaggtgacaaagtacaatttgaagaatttgcaaaagtagtaaggaatatgcgtgatgctgccaggttagaagagttacaggaagttgtcttagctgctgatttgctggaaggtgacatgatagctgggaagaacttggaagactttctaagaaatgttgggattaagtcacctaaagaagaggtagagaaaattcttcaatcagattttgtttctgaagataacatggtgaacattaaagactgtatgagggctttgagggacacccagaaattttccaattatattgatttcaggaaagaggcttcaaatctaaaattaccaaaggtaaacgagattaaagaagctgctaacatcttgtcacatgtcgataatggcaagattggtatacctgatttggagcatgccttgaaatgtttgaatgttaatttaactgaggaggacttcaatgaagcccttaactgttgtaacgtcagtgataatatggaggtggatttaaaagatttcttaatgaaaatgaaagaaagtccacatttccaaaagtccaaggctacacagatactcttagctactacccaaattctccagaatgatctagttgatgtctctgacctcaagacattattgatggacaaggaccttcatacagctaatgctatacttactgtaatgttaagacatgtacctgaacatggttagtagtttcaatgcgtctatcttataaggaccatcctctaccacaggggtggaaggtctatgggtaggacatgcagggatggagggtatcctgtggaagctgaggtgggatgactgctggacactggtactgcccctacaggtgtgccaaccctgagcttcatggggccaaacaaatggggaagtcagagctcatcttatccctgtgtgagtccactgacagtacctaggaggtgagattattttgtgaactgactgacatgcacagtggtcaatcagaatgccatccatagagtaaaacagggtcctggaggcccttttggtttttggaaggtaaattatgatgatatccagggataccagggggtgttgcacatagtggtggctcagggcagcagatatttataaatataaaaaataattttactattttaatgacaggtatagctgaatattatccatgatgggttcttaaaatgagttggggagtatttttttgttttgttttttaaaagagacttttttcttccttgaatgttgagtagaattcataggtgaagccatgtgggccaagagtttttttgtgaaaggctttggattatttatttaatgtctttaaatgaataggattaacaaggtattctattttcttgttagttttggcaagctatgtttttagaggaattcgttcattagatctgccttttcaaatgtattgaataaagttgttctctttttgacatctga

//