LOCUS       NR_034295                100 bp    RNA     linear   INV 04-JUL-2020
DEFINITION  Apis mellifera microRNA mir-375 (Mir375), microRNA.
ACCESSION   NR_034295 NR_039403
VERSION     NR_034295.1
KEYWORDS    RefSeq.
SOURCE      Apis mellifera (honey bee)
  ORGANISM  Apis mellifera
            Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
            Pterygota; Neoptera; Endopterygota; Hymenoptera; Apocrita;
            Aculeata; Apoidea; Anthophila; Apidae; Apis.
REFERENCE   1  (bases 1 to 100)
  AUTHORS   Greenberg JK, Xia J, Zhou X, Thatcher SR, Gu X, Ament SA, Newman
            TC, Green PJ, Zhang W, Robinson GE and Ben-Shahar Y.
  TITLE     Behavioral plasticity in honey bees is associated with differences
            in brain microRNA transcriptome
  JOURNAL   Genes Brain Behav. 11 (6), 660-670 (2012)
   PUBMED   22409512
REFERENCE   2  (bases 1 to 100)
  AUTHORS   Weaver DB, Anzola JM, Evans JD, Reid JG, Reese JT, Childs KL,
            Zdobnov EM, Samanta MP, Miller J and Elsik CG.
  TITLE     Computational and transcriptional evidence for microRNAs in the
            honey bee genome
  JOURNAL   Genome Biol. 8 (6), R97 (2007)
   PUBMED   17543122
REFERENCE   3  (bases 1 to 100)
  AUTHORS   Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A and Enright
            AJ.
  TITLE     miRBase: microRNA sequences, targets and gene nomenclature
  JOURNAL   Nucleic Acids Res. 34 (Database issue), D140-D144 (2006)
   PUBMED   16381832
COMMENT     PROVISIONAL REFSEQ: This record is based on preliminary annotation
            provided by NCBI staff in collaboration with miRBase. The reference
            sequence was derived from QIUM02000014.1.
            
            On Sep 3, 2011 this sequence version replaced NR_039403.1.
            
            Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs
            that are involved in post-transcriptional regulation of gene
            expression in multicellular organisms by affecting both the
            stability and translation of mRNAs. miRNAs are transcribed by RNA
            polymerase II as part of capped and polyadenylated primary
            transcripts (pri-miRNAs) that can be either protein-coding or
            non-coding. The primary transcript is cleaved by the Drosha
            ribonuclease III enzyme to produce an approximately 70-nt stem-loop
            precursor miRNA (pre-miRNA), which is further cleaved by the
            cytoplasmic Dicer ribonuclease to generate the mature miRNA and
            antisense miRNA star (miRNA*) products. The mature miRNA is
            incorporated into a RNA-induced silencing complex (RISC), which
            recognizes target mRNAs through imperfect base pairing with the
            miRNA and most commonly results in translational inhibition or
            destabilization of the target mRNA. The RefSeq represents the
            predicted microRNA stem-loop. [provided by RefSeq, Sep 2009].
            
            Sequence Note: This record represents a predicted microRNA
            stem-loop as defined by miRBase. Some sequence at the 5' and 3'
            ends may not be included in the intermediate precursor miRNA
            produced by Drosha cleavage.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-100               QIUM02000014.1     2479874-2479973     c
FEATURES             Location/Qualifiers
     source          1..100
                     /organism="Apis mellifera"
                     /mol_type="transcribed RNA"
                     /db_xref="taxon:7460"
                     /map="LG3"
                     /linkage_group="LG3"
     gene            1..100
                     /gene="Mir375"
                     /gene_synonym="ame-mir-375"
                     /note="microRNA mir-375"
                     /db_xref="GeneID:100315687"
                     /db_xref="miRBase:MI0005740"
     precursor_RNA   1..100
                     /gene="Mir375"
                     /gene_synonym="ame-mir-375"
                     /product="microRNA mir-375"
                     /db_xref="GeneID:100315687"
                     /db_xref="miRBase:MI0005740"
     exon            1..100
                     /gene="Mir375"
                     /gene_synonym="ame-mir-375"
                     /inference="alignment:Splign:2.1.0"
     ncRNA           63..84
                     /ncRNA_class="miRNA"
                     /gene="Mir375"
                     /gene_synonym="ame-mir-375"
                     /product="ame-miR-375"
                     /db_xref="miRBase:MIMAT0004431"
                     /db_xref="GeneID:100315687"
                     /db_xref="miRBase:MI0005740"
ORIGIN      

atcgattgaattatcagtttggtgcatcgatcctaacgatcaacaaacttttcacttgaaagtttgttcgttcggctcgagttatcaaactgaatggatg

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