LOCUS       NR_033186               5454 bp    RNA     linear   PRI 25-SEP-2025
DEFINITION  Homo sapiens chromosome 1 putative open reading frame 220
            (C1orf220), transcript variant 1, long non-coding RNA.
ACCESSION   NR_033186
VERSION     NR_033186.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5454)
  AUTHORS   Huttlin,E.L., Ting,L., Bruckner,R.J., Gebreab,F., Gygi,M.P.,
            Szpyt,J., Tam,S., Zarraga,G., Colby,G., Baltier,K., Dong,R.,
            Guarani,V., Vaites,L.P., Ordureau,A., Rad,R., Erickson,B.K.,
            Wuhr,M., Chick,J., Zhai,B., Kolippakkam,D., Mintseris,J.,
            Obar,R.A., Harris,T., Artavanis-Tsakonas,S., Sowa,M.E., De
            Camilli,P., Paulo,J.A., Harper,J.W. and Gygi,S.P.
  TITLE     The BioPlex Network: A Systematic Exploration of the Human
            Interactome
  JOURNAL   Cell 162 (2), 425-440 (2015)
   PUBMED   26186194
REFERENCE   2  (bases 1 to 5454)
  AUTHORS   Willer,C.J., Schmidt,E.M., Sengupta,S., Peloso,G.M., Gustafsson,S.,
            Kanoni,S., Ganna,A., Chen,J., Buchkovich,M.L., Mora,S.,
            Beckmann,J.S., Bragg-Gresham,J.L., Chang,H.Y., Demirkan,A., Den
            Hertog,H.M., Do,R., Donnelly,L.A., Ehret,G.B., Esko,T.,
            Feitosa,M.F., Ferreira,T., Fischer,K., Fontanillas,P., Fraser,R.M.,
            Freitag,D.F., Gurdasani,D., Heikkila,K., Hypponen,E., Isaacs,A.,
            Jackson,A.U., Johansson,A., Johnson,T., Kaakinen,M., Kettunen,J.,
            Kleber,M.E., Li,X., Luan,J., Lyytikainen,L.P., Magnusson,P.K.E.,
            Mangino,M., Mihailov,E., Montasser,M.E., Muller-Nurasyid,M.,
            Nolte,I.M., O'Connell,J.R., Palmer,C.D., Perola,M., Petersen,A.K.,
            Sanna,S., Saxena,R., Service,S.K., Shah,S., Shungin,D., Sidore,C.,
            Song,C., Strawbridge,R.J., Surakka,I., Tanaka,T., Teslovich,T.M.,
            Thorleifsson,G., Van den Herik,E.G., Voight,B.F., Volcik,K.A.,
            Waite,L.L., Wong,A., Wu,Y., Zhang,W., Absher,D., Asiki,G.,
            Barroso,I., Been,L.F., Bolton,J.L., Bonnycastle,L.L., Brambilla,P.,
            Burnett,M.S., Cesana,G., Dimitriou,M., Doney,A.S.F., Doring,A.,
            Elliott,P., Epstein,S.E., Ingi Eyjolfsson,G., Gigante,B.,
            Goodarzi,M.O., Grallert,H., Gravito,M.L., Groves,C.J., Hallmans,G.,
            Hartikainen,A.L., Hayward,C., Hernandez,D., Hicks,A.A., Holm,H.,
            Hung,Y.J., Illig,T., Jones,M.R., Kaleebu,P., Kastelein,J.J.P.,
            Khaw,K.T., Kim,E., Klopp,N., Komulainen,P., Kumari,M.,
            Langenberg,C., Lehtimaki,T., Lin,S.Y., Lindstrom,J., Loos,R.J.F.,
            Mach,F., McArdle,W.L., Meisinger,C., Mitchell,B.D., Muller,G.,
            Nagaraja,R., Narisu,N., Nieminen,T.V.M., Nsubuga,R.N., Olafsson,I.,
            Ong,K.K., Palotie,A., Papamarkou,T., Pomilla,C., Pouta,A.,
            Rader,D.J., Reilly,M.P., Ridker,P.M., Rivadeneira,F., Rudan,I.,
            Ruokonen,A., Samani,N., Scharnagl,H., Seeley,J., Silander,K.,
            Stancakova,A., Stirrups,K., Swift,A.J., Tiret,L.,
            Uitterlinden,A.G., van Pelt,L.J., Vedantam,S., Wainwright,N.,
            Wijmenga,C., Wild,S.H., Willemsen,G., Wilsgaard,T., Wilson,J.F.,
            Young,E.H., Zhao,J.H., Adair,L.S., Arveiler,D., Assimes,T.L.,
            Bandinelli,S., Bennett,F., Bochud,M., Boehm,B.O., Boomsma,D.I.,
            Borecki,I.B., Bornstein,S.R., Bovet,P., Burnier,M., Campbell,H.,
            Chakravarti,A., Chambers,J.C., Chen,Y.I., Collins,F.S.,
            Cooper,R.S., Danesh,J., Dedoussis,G., de Faire,U., Feranil,A.B.,
            Ferrieres,J., Ferrucci,L., Freimer,N.B., Gieger,C., Groop,L.C.,
            Gudnason,V., Gyllensten,U., Hamsten,A., Harris,T.B., Hingorani,A.,
            Hirschhorn,J.N., Hofman,A., Hovingh,G.K., Hsiung,C.A.,
            Humphries,S.E., Hunt,S.C., Hveem,K., Iribarren,C., Jarvelin,M.R.,
            Jula,A., Kahonen,M., Kaprio,J., Kesaniemi,A., Kivimaki,M.,
            Kooner,J.S., Koudstaal,P.J., Krauss,R.M., Kuh,D., Kuusisto,J.,
            Kyvik,K.O., Laakso,M., Lakka,T.A., Lind,L., Lindgren,C.M.,
            Martin,N.G., Marz,W., McCarthy,M.I., McKenzie,C.A., Meneton,P.,
            Metspalu,A., Moilanen,L., Morris,A.D., Munroe,P.B., Njolstad,I.,
            Pedersen,N.L., Power,C., Pramstaller,P.P., Price,J.F., Psaty,B.M.,
            Quertermous,T., Rauramaa,R., Saleheen,D., Salomaa,V.,
            Sanghera,D.K., Saramies,J., Schwarz,P.E.H., Sheu,W.H.,
            Shuldiner,A.R., Siegbahn,A., Spector,T.D., Stefansson,K.,
            Strachan,D.P., Tayo,B.O., Tremoli,E., Tuomilehto,J., Uusitupa,M.,
            van Duijn,C.M., Vollenweider,P., Wallentin,L., Wareham,N.J.,
            Whitfield,J.B., Wolffenbuttel,B.H.R., Ordovas,J.M., Boerwinkle,E.,
            Palmer,C.N.A., Thorsteinsdottir,U., Chasman,D.I., Rotter,J.I.,
            Franks,P.W., Ripatti,S., Cupples,L.A., Sandhu,M.S., Rich,S.S.,
            Boehnke,M., Deloukas,P., Kathiresan,S., Mohlke,K.L., Ingelsson,E.
            and Abecasis,G.R.
  CONSRTM   Global Lipids Genetics Consortium
  TITLE     Discovery and refinement of loci associated with lipid levels
  JOURNAL   Nat Genet 45 (11), 1274-1283 (2013)
   PUBMED   24097068
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL513013.12.
            
            On Sep 23, 2025 this sequence version replaced NR_033186.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK092849.1, BC136727.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA2149876
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-113               AL513013.12        47361-47473
            114-804             AL513013.12        49801-50491
            805-5454            AL513013.12        51682-56331
FEATURES             Location/Qualifiers
     source          1..5454
                     /organism="Homo sapiens"
                     /mol_type="transcribed RNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q25.2"
     gene            1..5454
                     /gene="C1orf220"
                     /note="chromosome 1 putative open reading frame 220"
                     /db_xref="GeneID:400798"
                     /db_xref="HGNC:HGNC:33805"
     ncRNA           1..5454
                     /ncRNA_class="lncRNA"
                     /gene="C1orf220"
                     /product="chromosome 1 putative open reading frame 220,
                     transcript variant 1"
                     /db_xref="GeneID:400798"
                     /db_xref="HGNC:HGNC:33805"
     exon            1..113
                     /gene="C1orf220"
                     /inference="alignment:Splign:2.1.0"
     exon            114..804
                     /gene="C1orf220"
                     /inference="alignment:Splign:2.1.0"
     exon            805..5454
                     /gene="C1orf220"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2291..2296
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C1orf220"
                     /note="hexamer: AATAAA"
     polyA_site      2313
                     /gene="C1orf220"
     regulatory      5434..5439
                     /regulatory_class="polyA_signal_sequence"
                     /gene="C1orf220"
                     /note="hexamer: AATAAA"
     polyA_site      5454
                     /gene="C1orf220"
                     /note="major polyA site"
ORIGIN      

agccaccgcctcttctcggcttcctcttgctttacagtaactctcctcctggggaaaaggcttttcacggagcaggctcggagcctacggggctggcctcggactggatggggagggtgctcaacttgctggagtcatctctgctatggctttatttgccaacaacagagaacttgctctgcagcagccccaggctctctggggaccccacaggctatgcagatcccccaccccagaaccacagaaggagacagagcagaagcacaccccgtcttccaggcccaggacagctgctgagctccaggacacggactcttgaaggttgattttgactacttactaagctccagctgaaccagttccacttctttaaccttcccatgatccctgtgaggggtctgtggtattgctatttgcaagtaaagaaagtgagattgagggaggctgaaagacttggccccaagtcacaatgccctgctgaatgtggtgctgcctcctggatatcctgggtgcttcaacatcaacagctcttggcaagtgagtgggccacgaaggatggacgagggacatgggggagcaagcccagctgcacggttccagctctttccgccacatcacagcttctgcagttgggaagactgaacagtgatcttcagtttgttcgtcaaagggccaagaaatctgtgtcctcaccttctctgcttcaattctggtgctgcttaagccgattatcatttcatgccctaaaccaaaaaataaactctacaaacatcaacattacataggacaggatctggcccacagattgggggcaggagctgctttttcaatgagaagaatgaacagacctagtgggcgttgcctttagacccaggtaagaggaatcccagccttgggacattactttcaagggccaagcccataggccatccttctagaacattctttgggtagctagggcttcataagtcacttactgggtttgtcctccttgagtggactgtgttgtcggtgtgcacacctgtatttccatggaatggtatcttagtcctgctgctataacaatacctgagactgaaaaatgtataaacaatagacatttatttctcacagttctggaggctgggaaatccaagatcaaggcaccagctggtttggtgtctggcgagggctgctctctgcttccaaaatggtgccttggggctgggcgtgatggctcatacctataatcccagcactttgggaggccaaggcgggcagatcacctgaggtcaggaggttaagaccagcctggccaacatggtgaaaaccccatccctactaaaaatacaaaaaattagccaggcatggtgatgcatgcctgtaattccagctacttgggaggctgaggcaagagaattgcttgaacccaggaggcagaatttgcagtgagccgagattgcaccactgcactccagcctgagtgatagagcgagactctgtctcaaaagacaaacaaaaaaccaaaatggtgcctcattgctggatcttccaaaagggatgaacgtatgttctcgaatgacagaaaagacagaagggcagaaagtgtccaaactcactccatcaatcccttttataaggtgctaatcactccctaaacaccccatctcttattactgttgcactggggattcagtttcagcatgagttttggagggatacagacattcaaaccacagcattgtgcacactcctttttctatggaatggccaaggtgcagctatttgcagaggctctgacagagctccgctgtggagctggggtgtccacatgcctgtatggaagaactttcatggcaccggagcctggtgggaagagaagtgggctgggctatagactgggcaccagggactatcacctcgtgccaccacatttagtgtagagttccagagaggccacaaattcttcatttgaactggactccccagcctcatgttcctctgcaggatgtaaaaggtaatgccagcagacgttggcagtgctggagacacctggtgggcagaggttacctggctggagtggcaggtgtgaggagatgcctcccagcataaggaatgtgggcttctgttggatctcttgttccaggcctcacacatgttcaaggcagcctgggtatgtcttggcccattcaatccctcaaagccctgtttaattctcatcttgctgtcacctatgtggtgccaagaaacaagtcaccaaaataatgaaatgcctacctaagcttaaaaacaaaaccatgaggtctttctaaataaattatgaaaaagtgcaaactgcaggtccctgtaatgatttcaaagactccgttccaacaatgcattaatttaaaaagggagtataaggcaaaggggggtgattagaagaggaaggcagctgacatcaaactgaatataccaagtttcctcctcaaaaacgagtgtgcattatttgtggtgaccattcttggtattgttctattacgtaaaacacagcatagcatcattcttttagatgccattcatttaatatatgggcaaatgtacatggttaggctagactggagcacttgtctacactgcttaaaagaaaagatttactaaaaaaattcaaaggacaaacgaaagtgcaaagggaatgttaggtttaattaagaaatcagctctttaaagggcttaaccagaataattgttggtatgcaagtggggttgtgaattataaatgaatcattcattctttgaagaatgatctcttcttggaaaaggatctcttcttggaaagacttggggagcattttaagttgttgaaggccaggtgtggtggctcatgcctgtaattgcagaactttgggaggccaaggtgggtggattacctgaggtcaggagttcgagaccagcctggccaacatggtgaaaccctgtctctactaaaaatacaaaaattagctgggcatggtggcatgcgcctgtaatcccaactgcttaggaggctgaggcaggagaatcgcttgaacctgggaggcagaggttgcagtgagccatgatcgtgccactgcccttcagcctaggtggcagatactaataattactgagtcgttttaagtcggtaacatttgttaggtgtttattacatgctagttcctcagttccaagtatttagtcttcaccacaggcctaggattatgaccattttatagaggaggaaaatgaaggcctccaagtgccttgcctgaattacctagctaaatgctaggaaagcaaagacaagtacaacaggctgtctgcctttaagaagtttaccacctagtattttttaatgtaaattctctaataagttcaggccagcttcctcttccagctcatctgaatttggtgaatttcaataaaataaaacaatacgaaaaacgtttctacgcaattaactgttgtcatgtattataataggaataagggggaaagccgtcttatggaatattgagtccacacttgagaatcaattgcctgaagaacattcttatttccagattgtagcatggtctttttatgcctgaacaatgacaaaaagagtgatgattttgtaacaaaacctcagggacgcaattaacaagttgtcatttctaattcatgtggaaatgctgttttatttttcagagaattgtagcagtggtgttcatttaattaagaatctgatgttgcggaagggcaattgagtgaaatttataatattgtagacagacatgtatgcaaacacaaaagaaaattggttaaggatctaagtgccagcttattttcctttgaacagcccatttttacatgatttgtgagctgtttcataaaggaatcatataagtatattttatccttttaaagatattttacggtaaactcatctaactagtaattgtacaaggctcataaatagtcaaaaagaaaagtgcctgtaacttttgacaatattgaaggtgactacctctgtattagaaggcagtttaggatctagtagctttcccaactgcaagtaatggcatattctaatttatatgaacaacatcataaaaccaataaggtaaagaaaataggtttgaatgagaaagtattctgagaaaggtggggaatgggcgtcagatatggattggaaggagacaagagatcggaaaggtgacagaagagagcccccactgtggtggctactgcctgcaccttcaccaggaagtgttgctcacctgtccaagccacaagttctggtcatgtcgtagatccaagtgcctccaggtggatgtgccacttccaaggcccagccttcctaagccacctcaccttaaggtctggatacatttgttcacagtatgcactttttgagtgctaattatgtgccaggcactgggctaggtcctggggacacacccatgaacaaggagagcaggttcctggcctcttgcagctgacattctagtcagaggagacagtctgtaaacacatagataaataattgaaagagttgcacatggcgatttgcgctgagaaaataaagcaaggtaaagagatttaagtgtgagagaagaaaaggggctgtttaaagaggtggttagggaaggcctctctgaggtcaggacatctgagcagcgaaggagccagcgatgggaagcaccgggggcgggggtaggacactccagacggagcaagtacaaaggccctggggcaggaaggaccctgatgtgctggatgaggagcaagagggtgccagtatcgctgagctggagaagaggaagaaaagtgggagaggaagatgaagaagtcacagaggtcaggccatgtgggccttttaggcatggccaaatgcttggattctcttccaaggagaatgggaagtcattggaagatcttaagtagggacatgataagactgatttatactttccaattattactgtgactactctgtggggaccagattataggaagatgataataaggtgagtgaaaagagtggccagtcgtggcatccgcctccttccacagagatgagtacaggctgaagtcttgtccgtaagatgcttctgtggaagttacagggagctgaccctggccttggaactaactgtggtgggatcagagaggggggaagcagagatggtgccagctttggcccaaagatcagaagcagtaaggactctgtgcctctggcaaaaggacaactccatgttttctgtgcaaacatccaagttaccatttccccaggcgacattgcagctgtggggcctgtgaacaggacaacagctaaccattctgagtttaaaaaaatcaaggacagtaccctcatgtttataatatagggggcaaagcaaaatccattgacaagcatttcctttaaaatacagggaaggaagattccattgtctacaaattctaatggaaattaataaagatgagcaaatatca

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