2024-05-18 13:27:02, GGRNA.v2 : RefSeq release 222 (Jan, 2024)
LOCUS NR_032498 64 bp RNA linear PRI 11-JUL-2020 DEFINITION Macaca mulatta microRNA mir-375 (MIR375), microRNA. ACCESSION NR_032498 VERSION NR_032498.1 KEYWORDS RefSeq. SOURCE Macaca mulatta (Rhesus monkey) ORGANISM Macaca mulatta Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca. REFERENCE 1 (bases 1 to 64) AUTHORS Yue J, Sheng Y and Orwig KE. TITLE Identification of novel homologous microRNA genes in the rhesus macaque genome JOURNAL BMC Genomics 9, 8 (2008) PUBMED 18186931 REMARK Publication Status: Online-Only REFERENCE 2 (bases 1 to 64) AUTHORS Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A and Enright AJ. TITLE miRBase: microRNA sequences, targets and gene nomenclature JOURNAL Nucleic Acids Res. 34 (Database issue), D140-D144 (2006) PUBMED 16381832 COMMENT PROVISIONAL REFSEQ: This record is based on preliminary annotation provided by NCBI staff in collaboration with miRBase. The reference sequence was derived from QNVO02000079.1. Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]. Sequence Note: This record represents a predicted microRNA stem-loop as defined by miRBase. Some sequence at the 5' and 3' ends may not be included in the intermediate precursor miRNA produced by Drosha cleavage. PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-64 QNVO02000079.1 81809925-81809988 c FEATURES Location/Qualifiers source 1..64 /organism="Macaca mulatta" /mol_type="transcribed RNA" /db_xref="taxon:9544" /chromosome="12" /map="12" gene 1..64 /gene="MIR375" /gene_synonym="mml-mir-375" /note="microRNA mir-375" /db_xref="GeneID:100315529" /db_xref="miRBase:MI0007720" precursor_RNA 1..64 /gene="MIR375" /gene_synonym="mml-mir-375" /product="microRNA mir-375" /db_xref="GeneID:100315529" /db_xref="miRBase:MI0007720" exon 1..64 /gene="MIR375" /gene_synonym="mml-mir-375" /inference="alignment:Splign:2.1.0" ncRNA 40..61 /ncRNA_class="miRNA" /gene="MIR375" /gene_synonym="mml-mir-375" /product="mml-miR-375" /db_xref="miRBase:MIMAT0006302" /db_xref="GeneID:100315529" /db_xref="miRBase:MI0007720" ORIGIN
ccccgcgacgagcccctcgcacaaaccggacctgagcgttttgttcgttcggctcgcgtgaggc
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@meso_cacase at
DBCLS
This page is licensed under a
Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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