2024-05-18 12:55:49, GGRNA.v2 : RefSeq release 222 (Jan, 2024)
LOCUS NR_032203 63 bp RNA linear MAM 04-JUL-2020 DEFINITION Monodelphis domestica microRNA mir-375 (MIR375), microRNA. ACCESSION NR_032203 VERSION NR_032203.1 KEYWORDS RefSeq. SOURCE Monodelphis domestica (gray short-tailed opossum) ORGANISM Monodelphis domestica Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Didelphimorphia; Didelphidae; Monodelphis. REFERENCE 1 (bases 1 to 63) AUTHORS Devor EJ and Samollow PB. TITLE In vitro and in silico annotation of conserved and nonconserved microRNAs in the genome of the marsupial Monodelphis domestica JOURNAL J. Hered. 99 (1), 66-72 (2008) PUBMED 17965199 REFERENCE 2 (bases 1 to 63) AUTHORS Griffiths-Jones S, Grocock RJ, van Dongen S, Bateman A and Enright AJ. TITLE miRBase: microRNA sequences, targets and gene nomenclature JOURNAL Nucleic Acids Res. 34 (Database issue), D140-D144 (2006) PUBMED 16381832 COMMENT PROVISIONAL REFSEQ: This record is based on preliminary annotation provided by NCBI staff in collaboration with miRBase. The reference sequence was derived from AAFR03041735.1. Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]. Sequence Note: This record represents a predicted microRNA stem-loop as defined by miRBase. Some sequence at the 5' and 3' ends may not be included in the intermediate precursor miRNA produced by Drosha cleavage. PRIMARY REFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-63 AAFR03041735.1 931-993 FEATURES Location/Qualifiers source 1..63 /organism="Monodelphis domestica" /mol_type="transcribed RNA" /db_xref="taxon:13616" /chromosome="7" /map="7" gene 1..63 /gene="MIR375" /gene_synonym="mdo-mir-375; Mirn375" /note="microRNA mir-375" /db_xref="GeneID:100034264" /db_xref="miRBase:MI0005327" precursor_RNA 1..63 /gene="MIR375" /gene_synonym="mdo-mir-375; Mirn375" /product="microRNA mir-375" /db_xref="GeneID:100034264" /db_xref="miRBase:MI0005327" exon 1..63 /gene="MIR375" /gene_synonym="mdo-mir-375; Mirn375" /inference="alignment:Splign:2.0.8" ncRNA 38..60 /ncRNA_class="miRNA" /gene="MIR375" /gene_synonym="mdo-mir-375; Mirn375" /product="mdo-miR-375" /db_xref="miRBase:MIMAT0004138" /db_xref="GeneID:100034264" /db_xref="miRBase:MI0005327" ORIGIN
cccgcgccgagcccctcgcacaaaccggacctgagcgttttgttcgttcggctcgcgtgaggc
//
by
@meso_cacase at
DBCLS
This page is licensed under a
Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
[Full Text]