LOCUS       NM_213389               2082 bp    mRNA    linear   VRT 08-OCT-2023
DEFINITION  Danio rerio transmembrane 9 superfamily member 3 (tm9sf3), mRNA.
ACCESSION   NM_213389
VERSION     NM_213389.1
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 2082)
  AUTHORS   Bayes A, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A,
            Choudhary JS, Emes RD and Grant SG.
  TITLE     Evolution of complexity in the zebrafish synapse proteome
  JOURNAL   Nat Commun 8, 14613 (2017)
   PUBMED   28252024
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2082)
  AUTHORS   Pasquier J, Cabau C, Nguyen T, Jouanno E, Severac D, Braasch I,
            Journot L, Pontarotti P, Klopp C, Postlethwait JH, Guiguen Y and
            Bobe J.
  TITLE     Gene evolution and gene expression after whole genome duplication
            in fish: the PhyloFish database
  JOURNAL   BMC Genomics 17, 368 (2016)
   PUBMED   27189481
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2082)
  AUTHORS   Gomez-Marin C, Tena JJ, Acemel RD, Lopez-Mayorga M, Naranjo S, de
            la Calle-Mustienes E, Maeso I, Beccari L, Aneas I, Vielmas E,
            Bovolenta P, Nobrega MA, Carvajal J and Gomez-Skarmeta JL.
  TITLE     Evolutionary comparison reveals that diverging CTCF sites are
            signatures of ancestral topological associating domains borders
  JOURNAL   Proc Natl Acad Sci U S A 112 (24), 7542-7547 (2015)
   PUBMED   26034287
REFERENCE   4  (bases 1 to 2082)
  AUTHORS   Pruvot B, Laurens V, Salvadori F, Solary E, Pichon L and Chluba J.
  TITLE     Comparative analysis of nonaspanin protein sequences and expression
            studies in zebrafish
  JOURNAL   Immunogenetics 62 (10), 681-699 (2010)
   PUBMED   20820770
  REMARK    GeneRIF: A conserved TRAF2 binding domain is predicted in the
            cytoplasmic regions of TM9SF3.
REFERENCE   5  (bases 1 to 2082)
  AUTHORS   Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B,
            Yusuf S, Gerstein HC, Engert JC and Anand S.
  CONSRTM   DREAM investigators
  TITLE     Variation at the NFATC2 locus increases the risk of
            thiazolidinedione-induced edema in the Diabetes REduction
            Assessment with ramipril and rosiglitazone Medication (DREAM) study
  JOURNAL   Diabetes Care 33 (10), 2250-2253 (2010)
   PUBMED   20628086
  REMARK    GeneRIF: Observational study of gene-disease association,
            gene-environment interaction, and pharmacogenomic / toxicogenomic.
            (HuGE Navigator)
REFERENCE   6  (bases 1 to 2082)
  AUTHORS   Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt
            TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M,
            Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ,
            Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S,
            Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD,
            Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE
            and Hingorani AD.
  CONSRTM   ASCOT investigators; NORDIL investigators; BRIGHT Consortium
  TITLE     Gene-centric association signals for lipids and apolipoproteins
            identified via the HumanCVD BeadChip
  JOURNAL   Am J Hum Genet 85 (5), 628-642 (2009)
   PUBMED   19913121
  REMARK    GeneRIF: Observational study of gene-disease association. (HuGE
            Navigator)
REFERENCE   7  (bases 1 to 2082)
  AUTHORS   Kalen M, Wallgard E, Asker N, Nasevicius A, Athley E, Billgren E,
            Larson JD, Wadman SA, Norseng E, Clark KJ, He L, Karlsson-Lindahl
            L, Hager AK, Weber H, Augustin H, Samuelsson T, Kemmet CK, Utesch
            CM, Essner JJ, Hackett PB and Hellstrom M.
  TITLE     Combination of reverse and chemical genetic screens reveals
            angiogenesis inhibitors and targets
  JOURNAL   Chem Biol 16 (4), 432-441 (2009)
   PUBMED   19389629
REFERENCE   8  (bases 1 to 2082)
  AUTHORS   Song HD, Sun XJ, Deng M, Zhang GW, Zhou Y, Wu XY, Sheng Y, Chen Y,
            Ruan Z, Jiang CL, Fan HY, Zon LI, Kanki JP, Liu TX, Look AT and
            Chen Z.
  TITLE     Hematopoietic gene expression profile in zebrafish kidney marrow
  JOURNAL   Proc Natl Acad Sci U S A 101 (46), 16240-16245 (2004)
   PUBMED   15520368
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC046021.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC046021.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           SAMEA2168446, SAMEA2168447
                                           [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2082
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /db_xref="taxon:7955"
                     /chromosome="13"
                     /map="13"
     gene            1..2082
                     /gene="tm9sf3"
                     /gene_synonym="fb75h12; wu:fa94f05; wu:fb75h12; zgc:56246"
                     /note="transmembrane 9 superfamily member 3"
                     /db_xref="GeneID:406698"
                     /db_xref="ZFIN:ZDB-GENE-040426-2714"
     exon            1..190
                     /gene="tm9sf3"
                     /gene_synonym="fb75h12; wu:fa94f05; wu:fb75h12; zgc:56246"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    89..91
                     /gene="tm9sf3"
                     /gene_synonym="fb75h12; wu:fa94f05; wu:fb75h12; zgc:56246"
                     /note="upstream in-frame stop codon"
     CDS             98..1858
                     /gene="tm9sf3"
                     /gene_synonym="fb75h12; wu:fa94f05; wu:fb75h12; zgc:56246"
                     /codon_start=1
                     /product="transmembrane 9 superfamily member 3 precursor"
                     /protein_id="NP_998554.1"
                     /db_xref="GeneID:406698"
                     /db_xref="ZFIN:ZDB-GENE-040426-2714"
                     /translation="

MGLCKWTFEVVALTAVFSSFIPVRADEHEHKYTDKEEVVLWMNTVGPYHNRQETYKYFSLPFCVGTKKTISHYHETLGEALQGVELEFSGLDIKFKEEVLQTTYCDIELDKPKRDAFVYAIKNHYWYQMYIDDLPIWGIVGEADENGEDYYLWTYKKLEIGHNGNRIVDVNLTSEGKVKLVPNTRIPMSYSVKWKKSDVKFEDRFDKYLDPSFFQHRIHWFSIFNSFMMVIFLVGLVSMILMRTLRKDYARYSKEEEMDDMDRDPGDEYGWKQVHGDVFRPSSHPLIFSSLIGSGCQIFSVSLIVIILAMIEDLYTERGSMLSTAIFVYAATSPVNGYFGGSLYAKQGGRRWIKQMFIGAFLIPAMVCGTAFFINFIAIYYHASRAIPFGTMVAVCCICLFVILPLNLVGTILGRNLSGQPNFPCRVNAVPRPIPEKKWFMEPAVIVCLGGILPFGSIFIEMYFIFTSFWAYKIYYVYGFMMLVLVILCIVTVCVTIVCTYFLLNAEDYRWQWTSFLSAASTAVYVYMYSFYYYFFKTKMYGLFQTSFYFGYMAVFSTALGIMCGAVGYMGTSAFVRKIYTNVKID"

     sig_peptide     98..172
                     /gene="tm9sf3"
                     /gene_synonym="fb75h12; wu:fa94f05; wu:fb75h12; zgc:56246"
                     /inference="COORDINATES: ab initio prediction:SignalP:4.0"
     misc_feature    257..1666
                     /gene="tm9sf3"
                     /gene_synonym="fb75h12; wu:fa94f05; wu:fb75h12; zgc:56246"
                     /note="Endomembrane protein 70; Region: EMP70; pfam02990"
                     /db_xref="CDD:427094"
     exon            191..386
                     /gene="tm9sf3"
                     /gene_synonym="fb75h12; wu:fa94f05; wu:fb75h12; zgc:56246"
                     /inference="alignment:Splign:2.1.0"
     exon            387..509
                     /gene="tm9sf3"
                     /gene_synonym="fb75h12; wu:fa94f05; wu:fb75h12; zgc:56246"
                     /inference="alignment:Splign:2.1.0"
     exon            510..670
                     /gene="tm9sf3"
                     /gene_synonym="fb75h12; wu:fa94f05; wu:fb75h12; zgc:56246"
                     /inference="alignment:Splign:2.1.0"
     exon            671..748
                     /gene="tm9sf3"
                     /gene_synonym="fb75h12; wu:fa94f05; wu:fb75h12; zgc:56246"
                     /inference="alignment:Splign:2.1.0"
     exon            749..880
                     /gene="tm9sf3"
                     /gene_synonym="fb75h12; wu:fa94f05; wu:fb75h12; zgc:56246"
                     /inference="alignment:Splign:2.1.0"
     exon            881..1047
                     /gene="tm9sf3"
                     /gene_synonym="fb75h12; wu:fa94f05; wu:fb75h12; zgc:56246"
                     /inference="alignment:Splign:2.1.0"
     exon            1048..1142
                     /gene="tm9sf3"
                     /gene_synonym="fb75h12; wu:fa94f05; wu:fb75h12; zgc:56246"
                     /inference="alignment:Splign:2.1.0"
     exon            1143..1273
                     /gene="tm9sf3"
                     /gene_synonym="fb75h12; wu:fa94f05; wu:fb75h12; zgc:56246"
                     /inference="alignment:Splign:2.1.0"
     exon            1274..1413
                     /gene="tm9sf3"
                     /gene_synonym="fb75h12; wu:fa94f05; wu:fb75h12; zgc:56246"
                     /inference="alignment:Splign:2.1.0"
     exon            1414..1482
                     /gene="tm9sf3"
                     /gene_synonym="fb75h12; wu:fa94f05; wu:fb75h12; zgc:56246"
                     /inference="alignment:Splign:2.1.0"
     exon            1483..1629
                     /gene="tm9sf3"
                     /gene_synonym="fb75h12; wu:fa94f05; wu:fb75h12; zgc:56246"
                     /inference="alignment:Splign:2.1.0"
     exon            1630..1713
                     /gene="tm9sf3"
                     /gene_synonym="fb75h12; wu:fa94f05; wu:fb75h12; zgc:56246"
                     /inference="alignment:Splign:2.1.0"
     exon            1714..1790
                     /gene="tm9sf3"
                     /gene_synonym="fb75h12; wu:fa94f05; wu:fb75h12; zgc:56246"
                     /inference="alignment:Splign:2.1.0"
     exon            1791..2057
                     /gene="tm9sf3"
                     /gene_synonym="fb75h12; wu:fa94f05; wu:fb75h12; zgc:56246"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

aagacaaccactgtcatagaaccaggaagaaggaaggtgggatagcccccaaaaagataccatttcaaatcagtcgcagaattttccctagaaaaccatggggctctgcaagtggacgtttgaagtggttgccttgacggctgtttttagttcgttcataccagttcgagcagatgaacacgagcacaagtacacagataaagaagaggtggttttatggatgaatacagtgggcccttatcacaaccgacaggagacctataagtacttctccctaccgttctgtgtgggaacgaaaaaaactattagtcattatcatgagacattaggagaggcgctacagggggttgaattggagttcagcggtctggacatcaagttcaaagaggaggtgttgcagacgacatactgtgacattgaactagacaaacctaaaagagatgcatttgtctatgccatcaagaaccactactggtaccaaatgtacatagatgaccttcccatctggggaattgttggtgaagctgatgagaatggagaggactattacctttggacttacaaaaagctggagatcggacataatgggaacagaattgtggatgttaacctaaccagtgagggcaaggttaagcttgttccaaacacgagaattcccatgtcatactctgtcaagtggaagaaatctgatgtgaaatttgaggatagatttgacaaataccttgatccatctttctttcaacacagaattcactggttctcaatattcaactcattcatgatggtgattttcctggtgggccttgtttcaatgatcctgatgagaacattaaggaaagactatgccagatacagcaaagaggaggaaatggatgacatggatcgtgatcctggtgatgaatatggctggaagcaggttcacggggatgtgttcaggccatccagtcacccgctgatcttctcctccctcattggctctggctgtcaaattttttcagtttcccttatagtcataattttggccatgattgaggacttgtatacagagagagggtccatgttgagtacagccatatttgtttatgctgccacgtctccagtcaatggctactttggtggaagcctatatgcaaaacaaggagggagaagatggataaagcagatgttcattggagccttcctgattcctgcaatggtgtgtggtacagcgtttttcatcaacttcatcgccatctactaccatgcctcaagagcaatcccattcggcactatggttgcggtgtgctgcatctgcttatttgtaattctacctctgaacctggtggggacgatcctgggcagaaacctctccggacagcccaactttccttgtagagtcaatgctgtacccagacccatcccagaaaagaaatggtttatggagccagcagttatcgtgtgtttaggtggcatccttccattcggctcgatattcattgaaatgtacttcattttcacatctttctgggcctacaagatttactatgtgtatggatttatgatgctggtgctggtgatcctgtgcatcgttactgtctgcgtcaccattgtctgcacctacttccttctcaatgcagaagactacagatggcagtggacaagctttctctctgcagcgtcaacagcagtttatgtttacatgtactccttctactactatttcttcaaaacaaagatgtatggcttattccagacgtcattctactttggctacatggctgtgttcagcactgctctgggaatcatgtgtggagcggtgggttacatgggaacaagtgcctttgtgaggaagatctacacaaatgtgaaaatcgactaaaactctgcagagacgcagcagaagagccgacacttcctcccgatcgaaacgggcacaaagtctccatttattttgcaagatgagattgtggtatcttgtacaaaatctagttttccattttctcaatgaattaaacgttgcggcatgatgcatacacaagggtaaaccgagaggttaaataaacaggacttttaattttaaaaaaaaaaaaaaaaaaaaaaaaa

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