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2021-01-24 06:41:25, GGRNA.v2 : RefSeq release 203 (Nov, 2020)

LOCUS       NM_204202               1736 bp    mRNA    linear   VRT 25-JUN-2020
DEFINITION  Gallus gallus claudin 3 (CLDN3), mRNA.
ACCESSION   NM_204202
VERSION     NM_204202.1
KEYWORDS    RefSeq.
SOURCE      Gallus gallus (chicken)
  ORGANISM  Gallus gallus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
            Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes;
            Phasianidae; Phasianinae; Gallus.
REFERENCE   1  (bases 1 to 1736)
  AUTHORS   Danzinger S, Tan YY, Rudas M, Kastner MT, Weingartshofer S, Muhr D
            and Singer CF.
  CONSRTM   kConFab Investigators
  TITLE     Differential Claudin 3 and EGFR Expression Predicts BRCA1 Mutation
            in Triple-Negative Breast Cancer
  JOURNAL   Cancer Invest. 36 (7), 378-388 (2018)
   PUBMED   30142017
  REMARK    GeneRIF: CLDN3 expression and negative EGFR expression are
            associated with BRCA1 mutations in triple-negative breast cancers.
REFERENCE   2  (bases 1 to 1736)
  AUTHORS   Haddad N, El Andalousi J, Khairallah H, Yu M, Ryan AK and Gupta IR.
  TITLE     The tight junction protein claudin-3 shows conserved expression in
            the nephric duct and ureteric bud and promotes tubulogenesis in
            vitro
  JOURNAL   Am. J. Physiol. Renal Physiol. 301 (5), F1057-F1065 (2011)
   PUBMED   21775479
  REMARK    GeneRIF: Cldn3 may therefore promote tubule formation and expansion
            of the ureteric bud epithelium
REFERENCE   3  (bases 1 to 1736)
  AUTHORS   Haworth KE, El-Hanfy A, Prayag S, Healy C, Dietrich S and Sharpe P.
  TITLE     Expression of Claudin-3 during chick development
  JOURNAL   Gene Expr. Patterns 6 (1), 40-44 (2005)
   PUBMED   16024293
  REMARK    GeneRIF: The early expression domains of Claudin 3 in the
            developing chick embryo include the mesoderm surrounding Hensen's
            node and the head fold.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF334677.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF334677.1 [ECO:0000332]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1736
                     /organism="Gallus gallus"
                     /mol_type="mRNA"
                     /db_xref="taxon:9031"
                     /chromosome="19"
                     /map="19"
     gene            1..1736
                     /gene="CLDN3"
                     /gene_synonym="claudin-3"
                     /note="claudin 3"
                     /db_xref="CGNC:49012"
                     /db_xref="GeneID:374029"
     misc_feature    518..520
                     /gene="CLDN3"
                     /gene_synonym="claudin-3"
                     /note="upstream in-frame stop codon"
     CDS             632..1276
                     /gene="CLDN3"
                     /gene_synonym="claudin-3"
                     /codon_start=1
                     /product="claudin-3"
                     /protein_id="NP_989533.1"
                     /db_xref="CGNC:49012"
                     /db_xref="GeneID:374029"
                     /translation="
MSMGLEIGGVALSVLGWLCSIICCALPMWRVTAFIGNNIVTAQIIWEGLWMNCVVQSTGQMQCKVYDSMLALPQDLQAARALLVVAIVLAVLGLMVAIVGAQCTRCVEDETTKAKITIVSGVIFLLSGIMTLIPVSWSANTIIRDFYNPLVIDAQKRELGTSLYVGWAASALLLFGGALLCCSCPPKDERYAPSKVAYSAPRSAVTSYDKRNYV"
     misc_feature    638..1138
                     /gene="CLDN3"
                     /gene_synonym="claudin-3"
                     /note="PMP-22/EMP/MP20/Claudin family; Region:
                     PMP22_Claudin; cl21598"
                     /db_xref="CDD:328820"
ORIGIN      
gttgaaaaggcggggntgcaaggcccacaaacgtgtgctgtttttgcccccgtcccgttgttgttttgtgcntggtggggggttcagcccccatccttgcccacntccagcantaccggtgtgaagtgaggggttctcagctctcactgctgcctttcgggaaggttgaaggggtcaccggtggctgtgggttccccaaagggcaccgaggtgtaggtgggcagcagggcacacagcaagccaagagccgggcagcctccggccgtgcaccgcagccctccatctcagcaggctgtgacgatggcacccatcccaccccacgccccaaaaccaggcccgtgtcatggtggccatctcaggtggctctccccctccctccaatgcgccatctctgcaaacaaaggggagggtgtgggacactgcgagggagccagtggagaggagagtctggcggagaaaccccaccccgggcgggcgctgagcgagcgcagcccggccccagccccgccagcccatataagcacaggtgcacccaggtgtaagccgatccccacggctgcagcggcgagcggagcacagggtggtttcggtcagcgggttcctctctgccatcgcccgggagccggacaccatgtctatggggctggagatcggtggggtggccctgtcggtgctgggctggctgtgcagcatcatctgctgcgcgctgcccatgtggagggtgacggccttcatcggcaacaacatcgtgacggcgcagatcatctgggaagggctgtggatgaactgcgtggtgcagagcacggggcagatgcagtgcaaggtgtacgactccatgctggccctgccgcaggacctgcaggccgcccgcgcgctgctggtggtggccatcgtgctggccgtgctgggcctgatggtggccatcgtgggcgcccagtgcacgcgctgcgtggaggacgagaccaccaaggccaagatcaccatcgtctccggcgtcatcttcctgctctccggcatcatgaccctcatccccgtctcctggtcggccaacaccatcatccgggatttctacaacccgctggtgatcgacgctcagaagcgggagctgggcacgtccctctacgtgggctgggcggcctccgcgctgctgctctttgggggggccctgctgtgctgctcctgcccccccaaagacgagaggtacgcgcccagcaaggtggcttactccgccccgcgctctgccgttaccagctacgacaagaggaactatgtgtgagccccccgcgccccccggcccagccctatggggggctcagccgcccccgcgcccacttccagccccaccgccgggaccgccaccgccggggaccctccgccccgcgggccggggagagagctcctgtccccgagggtgcccagcacggtgggagcaggcggggaaatgacgggggggcgatgggatcggtgccggggtcagggccgggcagtgtgagcgggagccgggcgggcggctgtgtcaatactgatggtttcatgtaaacagagccggtttcgggttgccaggagagctgtgtgcagcagcgccaggaggaagctccgtgcccccccgccctgccccgccagcccccccgggaccccccgccggccgggcaccttctctccctgttacgcgtggtctgtacaagttacatttgtcaataaaggaatcctgttttggtaaaaaaaaaaaaaaaaaa
//

by @meso_cacase at DBCLS
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If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596. [Full Text]