LOCUS       NM_178302                867 bp    mRNA    linear   VRT 20-DEC-2022
DEFINITION  Danio rerio posterior neuron-specific homeobox (pnx), mRNA.
ACCESSION   NM_178302
VERSION     NM_178302.2
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 867)
  AUTHORS   Wotton KR, Weierud FK, Juarez-Morales JL, Alvares LE, Dietrich S
            and Lewis KE.
  TITLE     Conservation of gene linkage in dispersed vertebrate NK homeobox
            clusters
  JOURNAL   Dev Genes Evol 219 (9-10), 481-496 (2009)
   PUBMED   20112453
REFERENCE   2  (bases 1 to 867)
  AUTHORS   Bae YK, Shimizu T and Hibi M.
  TITLE     Patterning of proneuronal and inter-proneuronal domains by hairy-
            and enhancer of split-related genes in zebrafish neuroectoderm
  JOURNAL   Development 132 (6), 1375-1385 (2005)
   PUBMED   15716337
  REMARK    Erratum:[Development. 2006 Apr;133(8):1609]
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB067731.1.
            
            On Jun 3, 2003 this sequence version replaced NM_178302.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB067731.1, BC162069.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA4476742, SAMEA4476758
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..867
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /db_xref="taxon:7955"
                     /chromosome="10"
                     /map="10"
     gene            1..867
                     /gene="pnx"
                     /note="posterior neuron-specific homeobox"
                     /db_xref="GeneID:352939"
                     /db_xref="ZFIN:ZDB-GENE-030328-42"
     misc_feature    28..30
                     /gene="pnx"
                     /note="upstream in-frame stop codon"
     CDS             70..618
                     /gene="pnx"
                     /codon_start=1
                     /product="homeobox protein pnx"
                     /protein_id="NP_840087.1"
                     /db_xref="GeneID:352939"
                     /db_xref="ZFIN:ZDB-GENE-030328-42"
                     /translation="

MHEETSNSTLQGKTSFSIADILDPAKFNGTRETREISNNRESPKTTSPTQEPSAPNIANASAAKVKSKRIRTAFTLDQLRILERSFQSSHYLSVFERHCIASALGLSETQVKIWFQNRRTKWKKELDGHGGEEQSHCAPTALTQNPIMYALPGHHANHHVHYYPQQTHYLNTSFHPQMLMMY"

     misc_feature    70..171
                     /gene="pnx"
                     /note="propagated from UniProtKB/Swiss-Prot (F1R2J1.1);
                     Region: Important for interaction with tle3a.
                     /evidence=ECO:0000269|PubMed:12642490"
     misc_feature    139..258
                     /gene="pnx"
                     /note="propagated from UniProtKB/Swiss-Prot (F1R2J1.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    order(271..285,289..291,340..342,358..360,397..399,
                     403..408,415..420,424..432,436..441)
                     /gene="pnx"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238039"
     misc_feature    order(277..279,286..288,406..408,415..420,427..429)
                     /gene="pnx"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:238039"
     misc_feature    280..438
                     /gene="pnx"
                     /note="Homeobox domain; Region: Homeobox; pfam00046"
                     /db_xref="CDD:425441"
ORIGIN      

ggacatataacagcactctgagagttataaggtctcatttacttactgctctcagaagtcaccgtcaggatgcacgaagaaacgagcaattctacactgcaggggaaaacttccttctccatcgcagacattttggatcccgccaaattcaacgggacaagagaaacgcgggaaatctccaataacagagaatcaccgaagacgacttctccaactcaagaaccatcggctccaaacatcgctaatgcttctgctgcaaaagtgaagtcgaagcgcatccgcaccgcattcacactggatcagctgcgcatcctggagcgaagctttcagagcagccactatctgtcagtgttcgagcgccactgcatcgcctcagccctcggcctctcagaaacgcaagtcaagatctggtttcagaaccgacgcaccaaatggaagaaggagctggacggtcacggtggagaagagcagagccactgcgcacccacagcactcacgcaaaacccaatcatgtacgctctgcctggacatcacgctaaccatcatgtgcattattacccacaacaaacacattacctgaacacatctttccatcctcagatgcttatgatgtactgatgtactgttaaacttacatagaaatctgatgaaaatatatgcaaattacacatatgacaagttcatatttagatttagtttcccagcacaatgctgagtagctgctggaagggctttagctgcataaaacatatgccagtagttggtggttcattccactgtggataaatcagggactatccaaaaggaaaaggattgatagaatatttggatttacataaaaaaaaaaaaaaaaaaaaaaaaaaaaaa

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