LOCUS       NM_131771                935 bp    mRNA    linear   VRT 02-JUL-2023
DEFINITION  Danio rerio claudin 15-like a (cldn15la), mRNA.
ACCESSION   NM_131771 XM_694295
VERSION     NM_131771.2
KEYWORDS    RefSeq.
SOURCE      Danio rerio (zebrafish)
  ORGANISM  Danio rerio
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Actinopterygii; Neopterygii; Teleostei; Ostariophysi;
            Cypriniformes; Danionidae; Danioninae; Danio.
REFERENCE   1  (bases 1 to 935)
  AUTHORS   Morales RA, Rabahi S, Diaz OE, Salloum Y, Kern BC, Westling M, Luo
            X, Parigi SM, Monasterio G, Das S, Hernandez PP and Villablanca EJ.
  TITLE     Interleukin-10 regulates goblet cell numbers through Notch
            signaling in the developing zebrafish intestine
  JOURNAL   Mucosal Immunol 15 (5), 940-951 (2022)
   PUBMED   35840681
REFERENCE   2  (bases 1 to 935)
  AUTHORS   Levic DS, Yamaguchi N, Wang S, Knaut H and Bagnat M.
  TITLE     Knock-in tagging in zebrafish facilitated by insertion into
            non-coding regions
  JOURNAL   Development 148 (19) (2021)
   PUBMED   34495314
REFERENCE   3  (bases 1 to 935)
  AUTHORS   Hachimi M, Grabowski C, Campanario S, Herranz G, Baonza G, Serrador
            JM, Gomez-Lopez S, Barea MD, Bosch-Fortea M, Gilmour D, Bagnat M,
            Rodriguez-Fraticelli AE and Martin-Belmonte F.
  TITLE     Smoothelin-like 2 Inhibits Coronin-1B to Stabilize the Apical Actin
            Cortex during Epithelial Morphogenesis
  JOURNAL   Curr Biol 31 (4), 696-706 (2021)
   PUBMED   33275893
REFERENCE   4  (bases 1 to 935)
  AUTHORS   Park J, Levic DS, Sumigray KD, Bagwell J, Eroglu O, Block CL,
            Eroglu C, Barry R, Lickwar CR, Rawls JF, Watts SA, Lechler T and
            Bagnat M.
  TITLE     Lysosome-Rich Enterocytes Mediate Protein Absorption in the
            Vertebrate Gut
  JOURNAL   Dev Cell 51 (1), 7-20 (2019)
   PUBMED   31474562
REFERENCE   5  (bases 1 to 935)
  AUTHORS   Murdoch CC, Espenschied ST, Matty MA, Mueller O, Tobin DM and Rawls
            JF.
  TITLE     Intestinal Serum amyloid A suppresses systemic neutrophil
            activation and bactericidal activity in response to microbiota
            colonization
  JOURNAL   PLoS Pathog 15 (3), e1007381 (2019)
   PUBMED   30845179
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 935)
  AUTHORS   Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M,
            Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD,
            Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov
            GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W and
            Hertzano R.
  TITLE     RFX transcription factors are essential for hearing in mice
  JOURNAL   Nat Commun 6, 8549 (2015)
   PUBMED   26469318
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 935)
  AUTHORS   Alvers AL, Ryan S, Scherz PJ, Huisken J and Bagnat M.
  TITLE     Single continuous lumen formation in the zebrafish gut is mediated
            by smoothened-dependent tissue remodeling
  JOURNAL   Development 141 (5), 1110-1119 (2014)
   PUBMED   24504339
REFERENCE   8  (bases 1 to 935)
  AUTHORS   Baltzegar DA, Reading BJ, Brune ES and Borski RJ.
  TITLE     Phylogenetic revision of the claudin gene family
  JOURNAL   Mar Genomics 11, 17-26 (2013)
   PUBMED   23726886
REFERENCE   9  (bases 1 to 935)
  AUTHORS   Clelland ES and Kelly SP.
  TITLE     Tight junction proteins in zebrafish ovarian follicles: stage
            specific mRNA abundance and response to 17beta-estradiol, human
            chorionic gonadotropin, and maturation inducing hormone
  JOURNAL   Gen Comp Endocrinol 168 (3), 388-400 (2010)
   PUBMED   20553723
REFERENCE   10 (bases 1 to 935)
  AUTHORS   Lin B, Chen S, Cao Z, Lin Y, Mo D, Zhang H, Gu J, Dong M, Liu Z and
            Xu A.
  TITLE     Acute phase response in zebrafish upon Aeromonas salmonicida and
            Staphylococcus aureus infection: striking similarities and obvious
            differences with mammals
  JOURNAL   Mol Immunol 44 (4), 295-301 (2007)
   PUBMED   16630661
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            EH495796.1, EH507578.1 and EH533727.1.
            
            On Apr 4, 2014 this sequence version replaced NM_131771.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: EH495796.1, AF359427.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA4476743, SAMEA4476744
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-169               EH495796.1         32-200
            170-875             EH507578.1         179-884
            876-935             EH533727.1         2-61                c
FEATURES             Location/Qualifiers
     source          1..935
                     /organism="Danio rerio"
                     /mol_type="mRNA"
                     /strain="Tuebingen"
                     /db_xref="taxon:7955"
                     /chromosome="2"
                     /map="2"
     gene            1..935
                     /gene="cldn15la"
                     /gene_synonym="cldn10; cldn10l; cldn10l1a"
                     /note="claudin 15-like a"
                     /db_xref="GeneID:81591"
                     /db_xref="ZFIN:ZDB-GENE-010328-12"
     exon            1..314
                     /gene="cldn15la"
                     /gene_synonym="cldn10; cldn10l; cldn10l1a"
                     /inference="alignment:Splign:2.1.0"
     CDS             98..757
                     /gene="cldn15la"
                     /gene_synonym="cldn10; cldn10l; cldn10l1a"
                     /note="claudin 10 like; claudin 10-like 1a"
                     /codon_start=1
                     /product="claudin 15-like a"
                     /protein_id="NP_571846.2"
                     /db_xref="GeneID:81591"
                     /db_xref="ZFIN:ZDB-GENE-010328-12"
                     /translation="

MSTALEVTGYFMCLIGWVLTGLAVANDYWKISSIQGNVIVSNRLYENLWHACGEDSTGKANCQDFQSMLALPVHIQACRALVIIALLLGLVGLVLSTMGLNCIKIGSKTDESKGKNMFIGGIIYLIGGLCTMVGVSWYAARVVQEFNDPFYGGVRFELGSGLYIGWAGAALCMLGGGFQCSAYQRFSKSKEKGAYYPAGKPQTIYTTAQSNAETSKAYV"

     misc_feature    104..631
                     /gene="cldn15la"
                     /gene_synonym="cldn10; cldn10l; cldn10l1a"
                     /note="PMP-22/EMP/MP20/Claudin family; Region:
                     PMP22_Claudin; cl21598"
                     /db_xref="CDD:451326"
     exon            315..479
                     /gene="cldn15la"
                     /gene_synonym="cldn10; cldn10l; cldn10l1a"
                     /inference="alignment:Splign:2.1.0"
     exon            480..561
                     /gene="cldn15la"
                     /gene_synonym="cldn10; cldn10l; cldn10l1a"
                     /inference="alignment:Splign:2.1.0"
     exon            562..675
                     /gene="cldn15la"
                     /gene_synonym="cldn10; cldn10l; cldn10l1a"
                     /inference="alignment:Splign:2.1.0"
     exon            676..935
                     /gene="cldn15la"
                     /gene_synonym="cldn10; cldn10l; cldn10l1a"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

agctcaacagaagagcaatccaaacccatcgatcaggagcaagaacaggacacctatacagattcttcccttgaattttggatttctgaggttgaaaatgtctacagcattagaggtgacgggatacttcatgtgtttgatcggctgggttcttactggcctcgctgtggcaaatgattactggaagatttctagtattcaaggcaatgtgattgtttccaatcgcctctatgagaacttgtggcacgcttgtggagaggacagcactggaaaagccaactgtcaagactttcaatccatgctagctttgccagttcacattcaggcttgccgggcgttagtgatcattgccctgctcctggggctggttggtttagttttatctacaatggggctgaactgcattaagattggctcaaaaacagatgaatcaaaaggcaagaatatgttcatcggtggcattatctacctgataggaggtctttgcactatggtgggtgtatcttggtacgctgcacgtgttgtgcaagaattcaatgacccattctatgggggtgtcaggtttgagctgggctccgggctctacatcggctgggctggagcagcgctatgcatgttgggtggtggtttccagtgcagtgcctatcaaaggttctccaaatcaaaagaaaaaggggcatactacccagctggtaaaccacagaccatctataccacagctcaatcgaacgcagaaacatccaaagcctacgtctaagatttcccattttaacaaggctgaactgttgttacgttgatgtttgtttaactccattatgtttttgctacttttttcagttagttaggactatgttgtgttcaccataattgtaaaaagtaaatcaattttcatggatgcggcacgtgctgaataaaatatgccctctgattcaata

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