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2021-10-17 15:36:38, GGRNA.v2 : RefSeq release 207 (Jul, 2021)

LOCUS       NM_022956               1577 bp    mRNA    linear   ROD 20-JUN-2021
DEFINITION  Rattus norvegicus BarH-like homeobox 2 (Barhl2), mRNA.
ACCESSION   NM_022956
VERSION     NM_022956.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1577)
  AUTHORS   Lin SC, Kao SY, Chang JC, Liu YC, Yu EH, Tseng SH, Liu CJ and Chang
            KW.
  TITLE     Up-regulation of miR-187 modulates the advances of oral carcinoma
            by targeting BARX2 tumor suppressor
  JOURNAL   Oncotarget 7 (38), 61355-61365 (2016)
   PUBMED   27542258
REFERENCE   2  (bases 1 to 1577)
  AUTHORS   Mi Y, Zhao S, Zhang W, Zhang D, Weng J, Huang K, Sun H, Tang H,
            Zhang X, Sun X, Peng Z and Wen Y.
  TITLE     Down-regulation of Barx2 predicts poor survival in colorectal
            cancer
  JOURNAL   Biochem Biophys Res Commun 478 (1), 67-73 (2016)
   PUBMED   27453340
REFERENCE   3  (bases 1 to 1577)
  AUTHORS   Yamamoto H, Watanabe Y, Oikawa R, Morita R, Yoshida Y, Maehata T,
            Yasuda H and Itoh F.
  TITLE     BARHL2 Methylation Using Gastric Wash DNA or Gastric Juice Exosomal
            DNA is a Useful Marker For Early Detection of Gastric Cancer in an
            H. pylori-Independent Manner
  JOURNAL   Clin Transl Gastroenterol 7 (7), e184 (2016)
   PUBMED   27441821
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1577)
  AUTHORS   Chellappa R, Li S, Pauley S, Jahan I, Jin K and Xiang M.
  TITLE     Barhl1 regulatory sequences required for cell-specific gene
            expression and autoregulation in the inner ear and central nervous
            system
  JOURNAL   Mol Cell Biol 28 (6), 1905-1914 (2008)
   PUBMED   18212062
REFERENCE   5  (bases 1 to 1577)
  AUTHORS   Mo Z, Li S, Yang X and Xiang M.
  TITLE     Role of the Barhl2 homeobox gene in the specification of
            glycinergic amacrine cells
  JOURNAL   Development 131 (7), 1607-1618 (2004)
   PUBMED   14998930
REFERENCE   6  (bases 1 to 1577)
  AUTHORS   Saba R, Nakatsuji N and Saito T.
  TITLE     Mammalian BarH1 confers commissural neuron identity on dorsal cells
            in the spinal cord
  JOURNAL   J Neurosci 23 (6), 1987-1991 (2003)
   PUBMED   12657654
REFERENCE   7  (bases 1 to 1577)
  AUTHORS   Saito T, Sawamoto K, Okano H, Anderson DJ and Mikoshiba K.
  TITLE     Mammalian BarH homologue is a potential regulator of neural bHLH
            genes
  JOURNAL   Dev Biol 199 (2), 216-225 (1998)
   PUBMED   9698441
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB004056.1.
            On Aug 31, 2012 this sequence version replaced NM_022956.1.
            
            Summary: potential regulator of mammalian neural bHLH genes [RGD,
            Feb 2006].
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB004056.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMEA5760433
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1577              AB004056.1         5-1581
FEATURES             Location/Qualifiers
     source          1..1577
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14p22"
     gene            1..1577
                     /gene="Barhl2"
                     /gene_synonym="Barh; MBH1"
                     /note="BarH-like homeobox 2"
                     /db_xref="GeneID:65050"
                     /db_xref="RGD:620726"
     exon            1..685
                     /gene="Barhl2"
                     /gene_synonym="Barh; MBH1"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    37..39
                     /gene="Barhl2"
                     /gene_synonym="Barh; MBH1"
                     /note="upstream in-frame stop codon"
     CDS             70..1224
                     /gene="Barhl2"
                     /gene_synonym="Barh; MBH1"
                     /note="homeobox protein B-H1; bar-class homeodomain
                     protein MBH1; BarH-class homeodomain transcription factor"
                     /codon_start=1
                     /product="barH-like 2 homeobox protein"
                     /protein_id="NP_075245.1"
                     /db_xref="GeneID:65050"
                     /db_xref="RGD:620726"
                     /translation="
MTAMEGASGSSFGIDTILSGAGSGSPGMMNGDFRSLGEARTTDFRSQATPSPCSEIDTVGTAPSSPISVTLEPPEPHLVTDGPQHHHHLHHGQQPPPPSAPPAQSLQPSPQQQPPPQPQSAAQQLGSAAAAPRTSTSSFLIKDILGDSKPLAACAPYSTSVSSPHHTPKQECNAAHESFRPKLEQEDSKTKLDKREDSQSDIKCHGTKEEGDREITSSRESPPVRAKKPRKARTAFSDHQLNQLERSFERQKYLSVQDRMDLAAALNLTDTQVKTWYQNRRTKWKRQTAVGLELLAEAGNYSALQRMFPSPYFYHPSLLGSMDSTTAAAAAAAMYSSMYRTPPAPHPQLQRPLVPRVLIHGLGPGGQPALNPLSNPIPGTPHPR"
     misc_feature    70..471
                     /gene="Barhl2"
                     /gene_synonym="Barh; MBH1"
                     /note="propagated from UniProtKB/Swiss-Prot (O88181.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    529..780
                     /gene="Barhl2"
                     /gene_synonym="Barh; MBH1"
                     /note="propagated from UniProtKB/Swiss-Prot (O88181.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    order(757..771,775..777,826..828,844..846,883..885,
                     889..894,901..906,910..918,922..927)
                     /gene="Barhl2"
                     /gene_synonym="Barh; MBH1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238039"
     misc_feature    order(763..765,772..774,892..894,901..906,913..915)
                     /gene="Barhl2"
                     /gene_synonym="Barh; MBH1"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:238039"
     misc_feature    766..924
                     /gene="Barhl2"
                     /gene_synonym="Barh; MBH1"
                     /note="Homeobox domain; Region: Homeobox; pfam00046"
                     /db_xref="CDD:278475"
     misc_feature    1159..1221
                     /gene="Barhl2"
                     /gene_synonym="Barh; MBH1"
                     /note="propagated from UniProtKB/Swiss-Prot (O88181.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     STS             524..591
                     /gene="Barhl2"
                     /gene_synonym="Barh; MBH1"
                     /standard_name="Barhl2"
                     /db_xref="UniSTS:507945"
     exon            686..911
                     /gene="Barhl2"
                     /gene_synonym="Barh; MBH1"
                     /inference="alignment:Splign:2.1.0"
     exon            912..1574
                     /gene="Barhl2"
                     /gene_synonym="Barh; MBH1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
gatcgatagtttcccttgtttggtcccggaggcggctgatccgcggagtggcgtggacctcatgtagaaatgacagcaatggaaggggccagcgggtcgagttttggaatagacacgattttgtccggtgccggttccggcagtccgggcatgatgaacggagatttccgatcgctcggtgaagcgaggaccacggattttaggagccaggccaccccgtcaccctgttcggagattgataccgtgggaacggcgccctcttcaccgatctcggtcaccctggagcccccggagccgcatcttgtgacagacggaccccagcatcaccatcacctccaccacggccaacagccaccgccaccgtccgcgccccccgcgcaaagtttgcagccttctccccaacagcaaccgccgccgcagccgcagtctgcagcccagcaactgggctcggccgccgcggcccccaggacttccacctcttcctttttaattaaggacatcttgggagacagcaaacccctggcggcttgtgcaccctacagcaccagcgtttcttctcctcatcacaccccgaagcaggagtgcaacgcggcgcacgagagcttcaggccaaagctggagcaggaggacagcaaaaccaagctggacaagagggaagactctcagagcgacatcaaatgccacggaacaaaggaggaaggagaccgggagattacaagtagccgagagagtccccctgtgagagccaagaaacctcgaaaggccaggacagctttctcggaccaccagctcaatcaactggaacgtagctttgagcggcagaagtacctcagtgtacaggaccgcatggacctggcagctgcactcaacctcactgatacccaagtcaagacctggtaccagaaccgcagaaccaagtggaagcggcagactgcagtgggcctggagttgcttgccgaggcggggaactactccgcgctgcagaggatgtttccgtcgccttatttctaccacccaagcctgctggggagcatggacagcacgacggcggccgcggcggccgcggcaatgtacagcagcatgtaccgaactcctcctgcaccccatccgcagctgcagcggccactggtgccccgcgtgctcatccacggcctggggcctgggggacagccggccctcaaccctttgtccaaccccatcccaggcaccccgcatccccggtgaggaaggagggacagtgcagcccgagcagccctccaggtttccacccggccgccgacagctgccccacctctccccgcaccaaaccaacaggaatagaggcagacgagtaaagggggggagctcaccggtgggctgggtccccaaggaccggccagccctctgttctccatctgccccctcagaggcagggccgcaaagctccccaacagtgtgactggagaaaatactgaccccactgaaagtgcaaccagtaagtgaaaacacccacccacccacccacccacacacacacacaaaatgaaccctcgagttctttctttctttctttttttttttttttgaaaaaaaaaaaa
//

by @meso_cacase at DBCLS
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If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596. [Full Text]