LOCUS       NM_001181967            1335 bp    mRNA    linear   PLN 17-DEC-2024
DEFINITION  Saccharomyces cerevisiae S288C Emp46p (EMP46), partial mRNA.
ACCESSION   NM_001181967
VERSION     NM_001181967.1
DBLINK      BioProject: PRJNA128
KEYWORDS    RefSeq.
SOURCE      Saccharomyces cerevisiae S288C
  ORGANISM  Saccharomyces cerevisiae S288C
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
            Saccharomyces.
REFERENCE   1  (bases 1 to 1335)
  AUTHORS   Engel,S.R., Wong,E.D., Nash,R.S., Aleksander,S., Alexander,M.,
            Douglass,E., Karra,K., Miyasato,S.R., Simison,M., Skrzypek,M.S.,
            Weng,S. and Cherry,J.M.
  TITLE     New data and collaborations at the Saccharomyces Genome Database:
            updated reference genome, alleles, and the Alliance of Genome
            Resources
  JOURNAL   Genetics 220 (4) (2022)
   PUBMED   34897464
REFERENCE   2  (bases 1 to 1335)
  AUTHORS   Johnston,M., Hillier,L., Riles,L., Albermann,K., Andre,B.,
            Ansorge,W., Benes,V., Bruckner,M., Delius,H., Dubois,E.,
            Dusterhoft,A., Entian,K.D., Floeth,M., Goffeau,A., Hebling,U.,
            Heumann,K., Heuss-Neitzel,D., Hilbert,H., Hilger,F., Kleine,K.,
            Kotter,P., Louis,E.J., Messenguy,F., Mewes,H.W., Hoheisel,J.D. et
            al.
  TITLE     The nucleotide sequence of Saccharomyces cerevisiae chromosome XII
  JOURNAL   Nature 387 (6632 SUPPL), 87-90 (1997)
   PUBMED   9169871
REFERENCE   3  (bases 1 to 1335)
  AUTHORS   Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
            Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
            Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
            Oliver,S.G.
  TITLE     Life with 6000 genes
  JOURNAL   Science 274 (5287), 546 (1996)
   PUBMED   8849441
REFERENCE   4  (bases 1 to 1335)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-DEC-2024) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (bases 1 to 1335)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2015) Department of Genetics, Stanford
            University, Stanford, CA, USA
  REMARK    Protein update by submitter
REFERENCE   6  (bases 1 to 1335)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (06-FEB-2013) Department of Genetics, Stanford
            University, Stanford, CA, USA
  REMARK    Protein update by submitter
REFERENCE   7  (bases 1 to 1335)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2012) Department of Genetics, Stanford
            University, Stanford, CA, USA
  REMARK    Protein update by submitter
REFERENCE   8  (bases 1 to 1335)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (31-MAR-2011) Department of Genetics, Stanford
            University, Stanford, CA, USA
  REMARK    Sequence update by submitter
REFERENCE   9  (bases 1 to 1335)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (14-DEC-2009) Department of Genetics, Stanford
            University, Stanford, CA, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by SGD. This record
            is derived from an annotated genomic sequence (NC_001144).
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: SGD
            Annotation Status   :: Full Annotation
            Annotation Version  :: R64-4-1
            URL                 :: http://www.yeastgenome.org/
            ##Genome-Annotation-Data-END##
            COMPLETENESS: incomplete on both ends.
FEATURES             Location/Qualifiers
     source          1..1335
                     /organism="Saccharomyces cerevisiae S288C"
                     /mol_type="mRNA"
                     /strain="S288C"
                     /db_xref="taxon:559292"
                     /chromosome="XII"
     gene            <1..>1335
                     /gene="EMP46"
                     /locus_tag="YLR080W"
                     /db_xref="GeneID:850769"
     CDS             1..1335
                     /gene="EMP46"
                     /locus_tag="YLR080W"
                     /experiment="EXISTENCE:direct assay:GO:0000139 Golgi
                     membrane [PMID:12134087]"
                     /experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
                     reticulum [PMID:26928762]"
                     /experiment="EXISTENCE:direct assay:GO:0030246
                     carbohydrate binding [PMID:16439369]"
                     /experiment="EXISTENCE:genetic interaction:GO:0006888
                     endoplasmic reticulum to Golgi vesicle-mediated transport
                     [PMID:12134087]"
                     /experiment="EXISTENCE:physical interaction:GO:0030134
                     COPII-coated ER to Golgi transport vesicle
                     [PMID:12857885]"
                     /note="Integral membrane component of ER-derived
                     COPII-coated vesicles; functions in ER to Golgi transport;
                     EMP46 has a paralog, EMP47, that arose from the whole
                     genome duplication"
                     /codon_start=1
                     /product="Emp46p"
                     /protein_id="NP_013181.1"
                     /db_xref="GeneID:850769"
                     /db_xref="SGD:S000004070"
                     /translation="

MTTRKTASSLQLLGKITGTKAGTKQKKMNFINGLIWLYMCVWMVHGKVTQKDELKWNKGYSLPNLLEVTDQQKELSQWTLGDKVKLEEGRFVLTPGKNTKGSLWLKPEYSIKDAMTIEWTFRSFGFRGSTKGGLAFWLKQGNEGDSTELFGGSSKKFNGLMILLRLDDKLGESVTAYLNDGTKDLDIESSPYFASCLFQYQDSMVPSTLRLTYNPLDNHLLKLQMDNRVCFQTRKVKFMGSSPFRIGTSAINDASKESFEILKMKLYDGVIEDSLIPNVNPMGQPRVVTKVINSQTGEESFREKMPFSDKEESITSNELFEKMNKLEGKIMANDIDPLLRKMNKIVENERELIQRLRPLLDLKKTAISDDSFQDFLSMNANLDRLIKEQEKIRQDAKLYGKQTKGHDEIFSKISVWLALLIFIMITLAYYMFRINQDIKKVKLL"

     misc_feature    166..810
                     /gene="EMP46"
                     /locus_tag="YLR080W"
                     /note="EMP46 and EMP47 type 1 transmembrane proteins,
                     N-terminal lectin domain; Region: lectin_EMP46_EMP47;
                     cd06903"
                     /db_xref="CDD:173891"
     misc_feature    order(394..396,757..759)
                     /gene="EMP46"
                     /locus_tag="YLR080W"
                     /note="carbohydrate binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:173891"
     misc_feature    order(529..531,559..564,568..570)
                     /gene="EMP46"
                     /locus_tag="YLR080W"
                     /note="metal binding site [ion binding]; metal-binding
                     site"
                     /db_xref="CDD:173891"
ORIGIN      

atgactacaagaaagacagcttcctctcttcagcttttagggaaaatcacaggaacaaaagctggaactaagcaaaagaagatgaatttcattaatggactgatatggttatatatgtgtgtgtggatggtacacggaaaagtgacgcagaaggatgaattgaaatggaataaaggatactcgctaccaaatttgctagaagtgacagatcagcaaaaagaactttcacaatggactttgggtgacaaagtaaaacttgaagaagggaggtttgttttaactcctggaaagaacacaaagggttcactttggttgaaacctgaatattcaataaaggatgcaatgacaatagagtggacgtttagaagtttcgggttcagaggcagcacaaaggggggtcttgcattttggctgaagcaaggaaatgagggagatagtaccgagttatttggtggaagttcgaagaagtttaatggtttgatgatattgttacgattagacgataagttgggagagagcgtgacagcgtatttgaatgacggaacaaaagatcttgatattgaatcctcaccgtactttgcgtcatgtctgttccaataccaggattccatggtaccatcaacattaagattgacttacaatccactagataatcacttgttaaagttgcaaatggacaacagagtgtgtttccagacaaggaaagttaaatttatgggcagcagcccatttaggattggaacaagtgctatcaacgatgcatccaaagaatcgtttgaaatcttgaaaatgaagctttatgacggagttatagaggattcgctaattcctaacgtgaatcctatgggacaacccagagtggttactaaagtgatcaattctcaaactggtgaagagagtttcagggaaaagatgccattttctgataaggaagaaagtataacgagtaacgagcttttcgaaaagatgaacaagttggaggggaaaatcatggcaaatgatatcgatccattactccgcaagatgaacaagattgtggagaatgaacgtgaactgattcaacgtttaagaccactgttagatctgaagaaaacagccataagtgacgatagtttccaagattttctttcgatgaacgcaaacctggacagattgataaaagaacaagaaaaaattcgacaagatgccaagctgtatggcaagcagaccaaaggtcatgatgagatattttccaaaataagtgtatggttggcactgctgattttcattatgatcacattggcgtactacatgtttagaattaaccaagacatcaagaaggtcaaacttctgtaa

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