LOCUS       NM_001181321             999 bp    mRNA    linear   PLN 15-SEP-2023
DEFINITION  Saccharomyces cerevisiae S288C glyceraldehyde-3-phosphate
            dehydrogenase (phosphorylating) TDH3 (TDH3), partial mRNA.
ACCESSION   NM_001181321
VERSION     NM_001181321.3
DBLINK      BioProject: PRJNA128
KEYWORDS    RefSeq.
SOURCE      Saccharomyces cerevisiae S288C
  ORGANISM  Saccharomyces cerevisiae S288C
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
            Saccharomyces.
REFERENCE   1  (bases 1 to 999)
  AUTHORS   Engel,S.R., Wong,E.D., Nash,R.S., Aleksander,S., Alexander,M.,
            Douglass,E., Karra,K., Miyasato,S.R., Simison,M., Skrzypek,M.S.,
            Weng,S. and Cherry,J.M.
  TITLE     New data and collaborations at the Saccharomyces Genome Database:
            updated reference genome, alleles, and the Alliance of Genome
            Resources
  JOURNAL   Genetics 220 (4) (2022)
   PUBMED   34897464
REFERENCE   2  (bases 1 to 999)
  AUTHORS   Tettelin,H., Agostoni Carbone,M.L., Albermann,K., Albers,M.,
            Arroyo,J., Backes,U., Barreiros,T., Bertani,I., Bjourson,A.J.,
            Bruckner,M., Bruschi,C.V., Carignani,G., Castagnoli,L., Cerdan,E.,
            Clemente,M.L., Coblenz,A., Coglievina,M., Coissac,E., Defoor,E.,
            Del Bino,S., Delius,H., Delneri,D., de Wergifosse,P., Dujon,B.,
            Kleine,K. et al.
  TITLE     The nucleotide sequence of Saccharomyces cerevisiae chromosome VII
  JOURNAL   Nature 387 (6632 SUPPL), 81-84 (1997)
   PUBMED   9169869
REFERENCE   3  (bases 1 to 999)
  AUTHORS   Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
            Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
            Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
            Oliver,S.G.
  TITLE     Life with 6000 genes
  JOURNAL   Science 274 (5287), 546 (1996)
   PUBMED   8849441
REFERENCE   4  (bases 1 to 999)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (14-SEP-2023) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (bases 1 to 999)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2015) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Protein update by submitter
REFERENCE   6  (bases 1 to 999)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2012) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Protein update by submitter
REFERENCE   7  (bases 1 to 999)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (31-MAR-2011) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Sequence update by submitter
REFERENCE   8  (bases 1 to 999)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2009) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by SGD. This record
            is derived from an annotated genomic sequence (NC_001139).
            
            On Jul 30, 2012 this sequence version replaced NM_001181321.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: SGD
            Annotation Status   :: Full Annotation
            Annotation Version  :: R64-4-1
            URL                 :: http://www.yeastgenome.org/
            ##Genome-Annotation-Data-END##
            COMPLETENESS: incomplete on both ends.
FEATURES             Location/Qualifiers
     source          1..999
                     /organism="Saccharomyces cerevisiae S288C"
                     /mol_type="mRNA"
                     /strain="S288C"
                     /db_xref="taxon:559292"
                     /chromosome="VII"
     gene            <1..>999
                     /gene="TDH3"
                     /locus_tag="YGR192C"
                     /gene_synonym="GLD1; HSP35; HSP36; SSS2"
                     /db_xref="GeneID:853106"
     CDS             1..999
                     /gene="TDH3"
                     /locus_tag="YGR192C"
                     /gene_synonym="GLD1; HSP35; HSP36; SSS2"
                     /EC_number="1.2.1.12"
                     /experiment="EXISTENCE:direct assay:GO:0003723 RNA binding
                     [PMID:25288528]"
                     /experiment="EXISTENCE:direct assay:GO:0003729 mRNA
                     binding [PMID:18959479]"
                     /experiment="EXISTENCE:direct assay:GO:0004365
                     glyceraldehyde-3-phosphate dehydrogenase (NAD+)
                     (phosphorylating) activity [PMID:3905788]"
                     /experiment="EXISTENCE:direct assay:GO:0005634 nucleus
                     [PMID:26928762]"
                     /experiment="EXISTENCE:direct assay:GO:0005737 cytoplasm
                     [PMID:11914276]"
                     /experiment="EXISTENCE:direct assay:GO:0005739
                     mitochondrion [PMID:16823961|PMID:16962558|PMID:24769239]"
                     /experiment="EXISTENCE:direct assay:GO:0005811 lipid
                     droplet [PMID:10515935]"
                     /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
                     [PMID:11158358|PMID:26928762]"
                     /experiment="EXISTENCE:direct assay:GO:0005886 plasma
                     membrane [PMID:16622836]"
                     /experiment="EXISTENCE:direct assay:GO:0009277 fungal-type
                     cell wall [PMID:11158358]"
                     /experiment="EXISTENCE:direct assay:GO:1904408 melatonin
                     binding [PMID:31708896]"
                     /experiment="EXISTENCE:expression pattern:GO:0006094
                     gluconeogenesis [PMID:3905788]"
                     /experiment="EXISTENCE:expression pattern:GO:0006096
                     glycolytic process [PMID:3905788]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006915
                     apoptotic process [PMID:17726063]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0015886 heme
                     transport [PMID:27247412]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0020037 heme
                     binding [PMID:30012884]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0072593
                     reactive oxygen species metabolic process [PMID:17726063]"
                     /note="Glyceraldehyde-3-phosphate dehydrogenase (GAPDH),
                     isozyme 3; involved in glycolysis and gluconeogenesis;
                     tetramer that catalyzes the reaction of
                     glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate;
                     detected in the cytoplasm and cell wall; GAPDH-derived
                     antimicrobial peptides secreted by S. cerevisiae are
                     active against a wide variety of wine-related yeasts and
                     bacteria; binds AU-rich RNA"
                     /codon_start=1
                     /product="glyceraldehyde-3-phosphate dehydrogenase
                     (phosphorylating) TDH3"
                     /protein_id="NP_011708.3"
                     /db_xref="GeneID:853106"
                     /db_xref="SGD:S000003424"
                     /translation="

MVRVAINGFGRIGRLVMRIALSRPNVEVVALNDPFITNDYAAYMFKYDSTHGRYAGEVSHDDKHIIVDGKKIATYQERDPANLPWGSSNVDIAIDSTGVFKELDTAQKHIDAGAKKVVITAPSSTAPMFVMGVNEEKYTSDLKIVSNASCTTNCLAPLAKVINDAFGIEEGLMTTVHSLTATQKTVDGPSHKDWRGGRTASGNIIPSSTGAAKAVGKVLPELQGKLTGMAFRVPTVDVSVVDLTVKLNKETTYDEIKKVVKAAAEGKLKGVLGYTEDAVVSSDFLGDSHSSIFDASAGIQLSPKFVKLVSWYDNEYGYSTRVVDLVEHVAKA"

     misc_feature    <4..990
                     /gene="TDH3"
                     /locus_tag="YGR192C"
                     /gene_synonym="GLD1; HSP35; HSP36; SSS2"
                     /note="glyceraldehyde-3-phosphate dehydrogenase; Region:
                     PLN02272"
                     /db_xref="CDD:177912"
ORIGIN      

atggttagagttgctattaacggtttcggtagaatcggtagattggtcatgagaattgctttgtctagaccaaacgtcgaagttgttgctttgaacgacccattcatcaccaacgactacgctgcttacatgttcaagtacgactccactcacggtagatacgctggtgaagtttcccacgatgacaagcacatcattgtcgatggtaagaagattgctacttaccaagaaagagacccagctaacttgccatggggttcttccaacgttgacatcgccattgactccactggtgttttcaaggaattagacactgctcaaaagcacattgacgctggtgccaagaaggttgttatcactgctccatcttccaccgccccaatgttcgtcatgggtgttaacgaagaaaaatacacttctgacttgaagattgtttccaacgcttcttgtaccaccaactgtttggctccattggccaaggttatcaacgatgctttcggtattgaagaaggtttgatgaccactgtccactctttgactgctactcaaaagactgttgacggtccatcccacaaggactggagaggtggtagaaccgcttccggtaacatcatcccatcctccaccggtgctgctaaggctgtcggtaaggtcttgccagaattgcaaggtaagttgaccggtatggctttcagagtcccaaccgtcgatgtctccgttgttgacttgactgtcaagttgaacaaggaaaccacctacgatgaaatcaagaaggttgttaaggctgccgctgaaggtaagttgaagggtgttttgggttacaccgaagacgctgttgtctcctctgacttcttgggtgactctcactcttccatcttcgatgcttccgctggtatccaattgtctccaaagttcgtcaagttggtctcctggtacgacaacgaatacggttactctaccagagttgtcgacttggttgaacacgttgccaaggcttaa

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