LOCUS       NM_001180497            2001 bp    mRNA    linear   PLN 17-DEC-2024
DEFINITION  Saccharomyces cerevisiae S288C syntaxin-binding protein (SLY1),
            partial mRNA.
ACCESSION   NM_001180497
VERSION     NM_001180497.1
DBLINK      BioProject: PRJNA128
KEYWORDS    RefSeq.
SOURCE      Saccharomyces cerevisiae S288C
  ORGANISM  Saccharomyces cerevisiae S288C
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
            Saccharomyces.
REFERENCE   1  (bases 1 to 2001)
  AUTHORS   Engel,S.R., Wong,E.D., Nash,R.S., Aleksander,S., Alexander,M.,
            Douglass,E., Karra,K., Miyasato,S.R., Simison,M., Skrzypek,M.S.,
            Weng,S. and Cherry,J.M.
  TITLE     New data and collaborations at the Saccharomyces Genome Database:
            updated reference genome, alleles, and the Alliance of Genome
            Resources
  JOURNAL   Genetics 220 (4) (2022)
   PUBMED   34897464
REFERENCE   2  (bases 1 to 2001)
  AUTHORS   Jacq,C., Alt-Morbe,J., Andre,B., Arnold,W., Bahr,A., Ballesta,J.P.,
            Bargues,M., Baron,L., Becker,A., Biteau,N., Blocker,H., Blugeon,C.,
            Boskovic,J., Brandt,P., Bruckner,M., Buitrago,M.J., Coster,F.,
            Delaveau,T., del Rey,F., Dujon,B., Eide,L.G.,
            Garcia-Cantalejo,J.M., Goffeau,A., Gomez-Peris,A., Zaccaria,P. et
            al.
  TITLE     The nucleotide sequence of Saccharomyces cerevisiae chromosome IV
  JOURNAL   Nature 387 (6632 SUPPL), 75-78 (1997)
   PUBMED   9169867
REFERENCE   3  (bases 1 to 2001)
  AUTHORS   Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
            Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
            Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
            Oliver,S.G.
  TITLE     Life with 6000 genes
  JOURNAL   Science 274 (5287), 546 (1996)
   PUBMED   8849441
REFERENCE   4  (bases 1 to 2001)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (17-DEC-2024) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   5  (bases 1 to 2001)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (16-JAN-2015) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Protein update by submitter
REFERENCE   6  (bases 1 to 2001)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (06-FEB-2013) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Protein update by submitter
REFERENCE   7  (bases 1 to 2001)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (04-MAY-2012) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Protein update by submitter
REFERENCE   8  (bases 1 to 2001)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (31-MAR-2011) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Sequence update by submitter
REFERENCE   9  (bases 1 to 2001)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2009) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by SGD. This record
            is derived from an annotated genomic sequence (NC_001136).
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: SGD
            Annotation Status   :: Full Annotation
            Annotation Version  :: R64-4-1
            URL                 :: http://www.yeastgenome.org/
            ##Genome-Annotation-Data-END##
            COMPLETENESS: incomplete on both ends.
FEATURES             Location/Qualifiers
     source          1..2001
                     /organism="Saccharomyces cerevisiae S288C"
                     /mol_type="mRNA"
                     /strain="S288C"
                     /db_xref="taxon:559292"
                     /chromosome="IV"
     gene            <1..>2001
                     /gene="SLY1"
                     /locus_tag="YDR189W"
                     /db_xref="GeneID:851770"
     CDS             1..2001
                     /gene="SLY1"
                     /locus_tag="YDR189W"
                     /experiment="EXISTENCE:direct assay:GO:0000139 Golgi
                     membrane [PMID:15372079]"
                     /experiment="EXISTENCE:direct assay:GO:0000149 SNARE
                     binding [PMID:15958490]"
                     /experiment="EXISTENCE:direct assay:GO:0005783 endoplasmic
                     reticulum [PMID:10747087]"
                     /experiment="EXISTENCE:direct assay:GO:0005829 cytosol
                     [PMID:26928762]"
                     /experiment="EXISTENCE:direct assay:GO:0019905 syntaxin
                     binding [PMID:12186954|PMID:15372079]"
                     /experiment="EXISTENCE:direct assay:GO:0030134
                     COPII-coated ER to Golgi transport vesicle
                     [PMID:10747087]"
                     /experiment="EXISTENCE:genetic interaction:GO:0005783
                     endoplasmic reticulum [PMID:15958490]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006888
                     endoplasmic reticulum to Golgi vesicle-mediated transport
                     [PMID:9545229]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0006890
                     retrograde vesicle-mediated transport, Golgi to
                     endoplasmic reticulum [PMID:15958490]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0019905
                     syntaxin binding [PMID:12186954]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0035543
                     positive regulation of SNARE complex assembly
                     [PMID:12186954]"
                     /experiment="EXISTENCE:mutant phenotype:GO:0048280 vesicle
                     fusion with Golgi apparatus [PMID:8636207]"
                     /note="Hydrophilic protein involved in ER/Golgi vesicle
                     trafficking; SM (Sec1/Munc-18) family protein that binds
                     the tSNARE Sed5p and stimulates its assembly into a
                     trans-SNARE membrane-protein complex"
                     /codon_start=1
                     /product="syntaxin-binding protein"
                     /protein_id="NP_010475.1"
                     /db_xref="GeneID:851770"
                     /db_xref="SGD:S000002597"
                     /translation="

MAVEEIASRKDISLRDMQISAILKMLFLNKDLNNNDNITTITDDIFNQQEIIWKVLILDIKSTATISSVLRVNDLLKAGITVHSLIKQDRSPLPDVPAIYFVSPTKENIDIIVNDLKSDKYSEFYINFTSSLPRNLLEDLAQQVSITGKSDKIKQVYDQYLDFIVTEPELFSLEISNAYLTLNDPKTTEEEITGLCANIADGLFNTVLTINSIPIIRAAKGGPAEIIAEKLGTKLRDFVINTNSSSTSTLQGNDSLERGVLIILDRNIDFASMFSHSWIYQCMVFDIFKLSRNTVTIPLESKENGTDNTTAKPLATKKYDIEPNDFFWMENSHLPFPEAAENVEAALNTYKEEAAEITRKTGVTNISDLDPNSNNDTVQIQEVVKKLPELTAKKNTIDTHMNIFAALLSQLESKSLDTFFEVEQDPGSTKTRSRFLDILKDGKTNNLEDKLRSFIVLYLTSTTGLPKDFVQNVENYFKENDYDINALKYVYKLREFMQLSNMSLQNKSLEDGSDSAFKPSNLTLSGIYGLTEGKLQGGVGSLISGIKKLLPEKKTIPITNVVDAIMDPLNSSQKNLETTDSYLYIDPKITRGSHTRKPKRQSYNKSLVFVVGGGNYLEYQNLQEWAHSQLHNPKKVMYGSTAITTPAEFLNEISRLGASNSSNNDA"

     misc_feature    31..1983
                     /gene="SLY1"
                     /locus_tag="YDR189W"
                     /note="Proteins involved in synaptic transmission and
                     general secretion, Sec1 family [Intracellular trafficking
                     and secretion]; Region: SEC1; COG5158"
                     /db_xref="CDD:227487"
ORIGIN      

atggctgtggaggaaattgcgtcccgcaaggacattagtttaagagatatgcaaatctctgccatattaaaaatgctgtttttaaataaggatttgaacaacaacgacaacatcaccaccatcacagacgatatttttaaccagcaggagatcatctggaaggtgttgatactggacatcaagagcactgctaccatatcttctgttctcagagtcaatgacctgctgaaagctggtatcaccgttcattccttgattaaacaagacagatctcccttgccagatgtccctgccatatatttcgtctcccccacaaaggaaaacattgacattatagtcaatgacttgaaaagcgacaagtattctgaattttacatcaactttacctcatctctgcccagaaacctcctggaagatttggctcaacaagtctccatcacgggtaaatctgataaaatcaaacaagtttacgaccaatacctggacttcattgtaactgaaccggaactgttctcactagaaatttcaaacgcatacttgacattgaatgacccgaaaaccacagaagaggaaatcacgggcttatgcgccaacatcgcggacggtttattcaacactgtcttaacgatcaattctatccccattataagagcagctaagggtgggcctgctgagatcatcgctgagaaactgggtacaaaattacgtgatttcgtcatcaataccaattcctcctccacttccactttgcagggaaatgattctctggaaagaggagtgttgattattttggatagaaacatagattttgcctccatgttttcacattcgtggatttatcagtgcatggtctttgatattttcaaattatcaagaaacaccgttactattccacttgaaagtaaggaaaacggaactgacaataccaccgcaaaaccattagccacgaaaaaatatgatatagagccaaacgattttttttggatggaaaactctcatttgccattcccagaagctgcagagaacgttgaagcggcattgaatacgtacaaggaggaagccgcagaaattactaggaaaactggtgttaccaacatatcagatttggacccaaactcgaataatgatacggttcaaattcaggaagtcgtaaagaaactgccagagttaacagctaagaaaaatactattgatacacatatgaatatttttgctgcattgttgtcacaattggaaagtaaaagtcttgatactttctttgaagttgaacaagaccctggaagcaccaaaacaagatctaggtttttggatatactaaaagatggtaagacaaacaatcttgaggacaaactgagatcgtttattgttctttacttgacatcaacgacaggcttaccaaaggattttgtccaaaatgtggaaaactatttcaaggaaaacgattacgatatcaatgctttaaaatatgtttataagctaagagagttcatgcaattatcaaatatgtcgttacaaaataaatctttggaagatggatccgattccgctttcaaaccaagcaacttaacattatccggtatctatggcttaactgaaggcaaattacaaggaggtgtaggaagtttaatatcaggtattaagaagttactgcctgaaaagaaaaccatcccgataacaaatgttgttgatgcgataatggaccctttaaacagctctcaaaaaaatttggagactactgacagttacctatacatcgacccaaaaattacaaggggttcccataccagaaagccaaaaagacaatcttataataagtcactagtgtttgtagttggtggcggtaactacctagaatatcaaaacctccaagaatgggcacattcccagttgcataatcccaaaaaagtcatgtatggtagcacagccattaccacaccagctgaattcttaaatgagatttctcgccttggcgcaagtaatagcagcaacaacgatgcataa

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