LOCUS       NM_001171198            1523 bp    mRNA    linear   VRT 22-DEC-2019
DEFINITION  Xenopus tropicalis notochord homeobox (not), mRNA.
ACCESSION   NM_001171198
VERSION     NM_001171198.1
KEYWORDS    RefSeq.
SOURCE      Xenopus tropicalis (tropical clawed frog)
  ORGANISM  Xenopus tropicalis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae;
            Xenopus; Silurana.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CT025280.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CT025280.2, CF238496.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00028290, SAMD00028291
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1523
                     /organism="Xenopus tropicalis"
                     /mol_type="mRNA"
                     /db_xref="taxon:8364"
                     /chromosome="1"
                     /map="1"
     gene            1..1523
                     /gene="not"
                     /gene_synonym="flh; not-a; not-b; not1; noto; Xnot;
                     Xnot-2; Xnot1; Xnot2; Znot"
                     /note="notochord homeobox"
                     /db_xref="GeneID:100038059"
                     /db_xref="Xenbase:XB-GENE-478518"
     CDS             10..720
                     /gene="not"
                     /gene_synonym="flh; not-a; not-b; not1; noto; Xnot;
                     Xnot-2; Xnot1; Xnot2; Znot"
                     /note="homeobox protein; floating head"
                     /codon_start=1
                     /product="notochord homeobox"
                     /protein_id="NP_001164669.1"
                     /db_xref="GeneID:100038059"
                     /db_xref="Xenbase:XB-GENE-478518"
                     /translation="

MLHSPVFPAFGHHLAEHPAMSISSELPRTPKASFNIDSILSRADRPVPKVSMEMPSWQPPSPPSVPYRYSYGMMPYPPVWLIKPTVGYPSMAQQQPMRMPRGECPCPDPACKERGLLYSHCPNGSMNPLSWRTGPCKMKRIRTVFTPEQLERLEKEFLKQQYMVGTERVDLASTLNLTETQVKVWFQNRRIKWRKQSLEQKKAKLSQFGVIPADSSDHTDDSRETEEDEDDVDVEL"

     misc_feature    order(424..438,442..444,493..495,511..513,550..552,
                     556..561,568..573,577..585,589..594)
                     /gene="not"
                     /gene_synonym="flh; not-a; not-b; not1; noto; Xnot;
                     Xnot-2; Xnot1; Xnot2; Znot"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238039"
     misc_feature    order(430..432,439..441,559..561,568..573,580..582)
                     /gene="not"
                     /gene_synonym="flh; not-a; not-b; not1; noto; Xnot;
                     Xnot-2; Xnot1; Xnot2; Znot"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:238039"
     misc_feature    433..591
                     /gene="not"
                     /gene_synonym="flh; not-a; not-b; not1; noto; Xnot;
                     Xnot-2; Xnot1; Xnot2; Znot"
                     /note="Homeobox domain; Region: Homeobox; pfam00046"
                     /db_xref="CDD:425441"
ORIGIN      

agcggaaacatgttacacagccctgtctttcctgcatttgggcaccacttggcagagcaccccgccatgtccatctcctcggagctgcccaggaccccaaaagcttctttcaacattgactccattctctccagggctgacagaccggtccccaaagtctccatggagatgcccagttggcagcccccctctcccccatctgtgccctaccgctactcttatggcatgatgccctacccacccgtgtggctcatcaaacccacagtgggataccccagcatggcacaacagcagccaatgaggatgcccaggggagaatgcccatgcccggaccctgcctgtaaagagagaggtttactctactcccattgcccaaatggttccatgaaccctctttcatggaggacagggccctgcaagatgaagagaatccgcacagtgttcaccccagagcagctggagaggctggagaaagagtttctcaaacagcaatacatggttggcactgaaagggtggatctggcatcgacactgaacctcacagagacacaggttaaagtttggttccagaaccgacgcatcaagtggcggaagcagagtctggagcagaagaaagccaagctgtcccagtttggggtgatccctgcagacagctcagatcacactgatgacagcagggagaccgaggaggatgaggatgatgtggatgttgaactgtagggccccactgaacatacactagctgaattcatcttgggtagctccacaaagaaccaccccccaaaaaaagagcactacagtgaaggagatggtattggacttcaccaaatacttaaagactgaacatccaaaatccctctctgcatctctgaatttctaatgggcagtaatggtcggctttacttgccctttacgccctcctgcctccttaatactgaaaaaccttacaaggcactgagccagcactttgggtgtattggattatggactggggagaaacggatgatactgcatggacaatccataggtgctgtacctggggttggtcgatgggtgggtaataagactggggtgccccactcctgcccttgcaatctctgcctctttaaccaaatgttgggtgctgtgatcgcccaggttggaaacttaaatgtactttttgccttaatatttatagtaactgtgttacttccacagtcctgatgccttgccctgcgcctcccactagatacggtgggctagccctcaccccttcctgctgccagtgggggtgcccagcaacattggcccctgatggttgataagtgactgatttctgtgtgtatatatatatatatgtgtcagggtaatgggccccggcgccgtgtggatgagtctggcagcgctcaggataatgattatatgactgtacatgattgtattatttatactgctgcacgctgtgtgtcactgtgacttatttattggatctgctttttatataaagatttttttctattttacataaaaaaaaaaaaaaaaaa

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