LOCUS       NM_001105745            2407 bp    mRNA    linear   ROD 27-JUL-2024
DEFINITION  Rattus norvegicus POU class 2 homeobox 3 (Pou2f3), mRNA.
ACCESSION   NM_001105745 XM_001059708 XM_343378
VERSION     NM_001105745.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2407)
  AUTHORS   Glahder,J.A., Hansen,C.N., Vinther,J., Madsen,B.S. and Norrild,B.
  TITLE     A promoter within the E6 ORF of human papillomavirus type 16
            contributes to the expression of the E7 oncoprotein from a
            monocistronic mRNA
  JOURNAL   J Gen Virol 84 (Pt 12), 3429-3441 (2003)
   PUBMED   14645924
REFERENCE   2  (bases 1 to 2407)
  AUTHORS   Cabral,A., Fischer,D.F., Vermeij,W.P. and Backendorf,C.
  TITLE     Distinct functional interactions of human Skn-1 isoforms with Ese-1
            during keratinocyte terminal differentiation
  JOURNAL   J Biol Chem 278 (20), 17792-17799 (2003)
   PUBMED   12624109
REFERENCE   3  (bases 1 to 2407)
  AUTHORS   Andersen,B., Weinberg,W.C., Rennekampff,O., McEvilly,R.J.,
            Bermingham,J.R. Jr., Hooshmand,F., Vasilyev,V., Hansbrough,J.F.,
            Pittelkow,M.R., Yuspa,S.H. and Rosenfeld,M.G.
  TITLE     Functions of the POU domain genes Skn-1a/i and Tst-1/Oct-6/SCIP in
            epidermal differentiation
  JOURNAL   Genes Dev 11 (14), 1873-1884 (1997)
   PUBMED   9242494
REFERENCE   4  (bases 1 to 2407)
  AUTHORS   Yukawa,K., Yasui,T., Yamamoto,A., Shiku,H., Kishimoto,T. and
            Kikutani,H.
  TITLE     Epoc-1: a POU-domain gene expressed in murine epidermal basal cells
            and thymic stromal cells
  JOURNAL   Gene 133 (2), 163-169 (1993)
   PUBMED   8224904
REFERENCE   5  (bases 1 to 2407)
  AUTHORS   Andersen,B., Schonemann,M.D., Flynn,S.E., Pearse,R.V. 2nd, Singh,H.
            and Rosenfeld,M.G.
  TITLE     Skn-1a and Skn-1i: two functionally distinct Oct-2-related factors
            expressed in epidermis
  JOURNAL   Science 260 (5104), 78-82 (1993)
   PUBMED   7682011
  REMARK    Erratum:[Science. 1993 Dec 3;262(5139):1499.. PMID: 8248794]
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473975.1.
            
            On or before Oct 3, 2007 this sequence version replaced
            XM_343378.3, XM_001059708.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: L23862.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5756307,
                                           SAMEA5760383 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2407
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q22"
     gene            1..2407
                     /gene="Pou2f3"
                     /note="POU class 2 homeobox 3"
                     /db_xref="GeneID:116544"
                     /db_xref="RGD:621691"
     exon            1..103
                     /gene="Pou2f3"
                     /inference="alignment:Splign:2.1.0"
     CDS             76..1368
                     /gene="Pou2f3"
                     /note="Rov 1 pou-homeodomain protein; oct-11;
                     transcription factor Skn-1; octamer-binding transcription
                     factor 11; OTF-11; octamer-binding protein 11"
                     /codon_start=1
                     /product="POU domain, class 2, transcription factor 3"
                     /protein_id="NP_001099215.1"
                     /db_xref="GeneID:116544"
                     /db_xref="RGD:621691"
                     /translation="

MVNLEPMHTEIKMSGDVADSTDARSTFGQVESGNDRNGLDFNRQIKTEDLGDTLQQSLSHRPCHLSQGPTMMPGNQMSGDMASLHPLQQLVLVPGHLQSVSQFLLSQTPPGQQGLQPNLLSFPQQQSTLLLPQTGPGLTSQAVGRPGLSGSSLEPHLEASQHLPGPKHLPGPGGNDEPTDLEELEKFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNLSFKNMCKLKPLLEKWLNDAESSPSDPSASTPSSYPTLSEVFGRKRKKRTSIETNIRLTLEKRFQDNPKPSSEEISMIAEQLSMEKEVVRVWFCNRRQKEKRINCPVATPVKPPIYNSRLVSPSGSLGSLSVPPVHSTMPGTVTSSCSPGNNSRPSSPGSGLHASSPTASQNNSKAAMNPSSAAFNSSGSWYRWNHPAYLH"

     misc_feature    76..195
                     /gene="Pou2f3"
                     /note="propagated from UniProtKB/Swiss-Prot (P42571.2);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    253..318
                     /gene="Pou2f3"
                     /note="propagated from UniProtKB/Swiss-Prot (P42571.2);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    460..615
                     /gene="Pou2f3"
                     /note="propagated from UniProtKB/Swiss-Prot (P42571.2);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    601..825
                     /gene="Pou2f3"
                     /note="Found in Pit-Oct-Unc transcription factors; Region:
                     POU; smart00352"
                     /db_xref="CDD:197673"
     misc_feature    817..876
                     /gene="Pou2f3"
                     /note="propagated from UniProtKB/Swiss-Prot (P42571.2);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    898..1068
                     /gene="Pou2f3"
                     /note="Region: Homeodomain; pfam00046"
                     /db_xref="CDD:459649"
     misc_feature    1138..1314
                     /gene="Pou2f3"
                     /note="propagated from UniProtKB/Swiss-Prot (P42571.2);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     exon            104..172
                     /gene="Pou2f3"
                     /inference="alignment:Splign:2.1.0"
     exon            173..207
                     /gene="Pou2f3"
                     /inference="alignment:Splign:2.1.0"
     exon            208..312
                     /gene="Pou2f3"
                     /inference="alignment:Splign:2.1.0"
     exon            313..415
                     /gene="Pou2f3"
                     /inference="alignment:Splign:2.1.0"
     exon            416..498
                     /gene="Pou2f3"
                     /inference="alignment:Splign:2.1.0"
     exon            499..681
                     /gene="Pou2f3"
                     /inference="alignment:Splign:2.1.0"
     exon            682..823
                     /gene="Pou2f3"
                     /inference="alignment:Splign:2.1.0"
     exon            824..960
                     /gene="Pou2f3"
                     /inference="alignment:Splign:2.1.0"
     exon            961..1122
                     /gene="Pou2f3"
                     /inference="alignment:Splign:2.1.0"
     exon            1123..1189
                     /gene="Pou2f3"
                     /inference="alignment:Splign:2.1.0"
     exon            1190..1328
                     /gene="Pou2f3"
                     /inference="alignment:Splign:2.1.0"
     exon            1329..2407
                     /gene="Pou2f3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

gcttccccgggggccaggctggggcagcagcgagggacctgggggggcgctggctttggccccgcctggggcaggatggtgaatctggagcccatgcacacagagatcaagatgagtggggatgtcgctgattccacagatgcccgcagcacttttggtcaagtggagtcaggaaatgatcgaaatggcctagatttcaacagacagattaagacagaggatctgggtgacactttgcagcagagcctctcccacaggccatgccacctgagccaagggcctaccatgatgcctggaaaccaaatgtctggggacatggcttctctccatccacttcagcagcttgtgctggtccctggccacttacagtctgtatcccagtttctgctttcccagacccctcctgggcagcaaggtctgcagccgaatcttctctcctttccacagcaacagagcactctactcctcccacagacaggacctggcctcacctcccaggcagttggacgccctgggctgtcaggatcctctttagagccccacctggaagcttctcaacatctgccagggcccaagcatctgcctggccccggagggaatgacgaacccactgacctggaggagctggagaagttcgccaagaccttcaagcagaggcgcataaagctaggcttcacacagggggatgtgggattggcgatgggaaagctgtatggtaacgacttcagccagactaccatctcgagatttgaggccctcaacctgagtttcaagaacatgtgtaaactcaagccactgctggagaagtggctgaatgatgcagagtcctccccgtcagacccttcagcaagcactcccagctcgtaccccactctcagcgaagtatttggcaggaagaggaagaaacggaccagcatcgagaccaacatccgcctgactttggagaagcgatttcaagataaccctaaacccagctcggaagagatttccatgattgcggagcagttgtccatggagaaggaagtggtaagagtctggttctgcaatcgacgccaaaaggagaagagaatcaactgccctgtggccacacctgtcaagccgcccatctacaactcccggctggtctctccctcagggtctctgggctccctctcagtccctcctgtccacagcaccatgcctggaacagtaacgtcatcctgttcccctgggaacaacagcaggccctcgtctcccggctcaggactccatgccagcagccccacggcatctcaaaataactccaaagcagcaatgaacccctcctccgccgcctttaactcctcagggtcatggtaccgttggaaccatcccgcctacctccactgagaccaaaaacttcctcccgttccacctggcccctggttcccaccaggaggaagagcggccacaccttccacgtatggacagacactttgagactcggagcgggagaaatggccgctgctgaagagcaaacccacaatcttgccttctcctggatccagagcttccagagaaccaagctgtgaccaaaggccacactcttgccttgggctcttgatcaccccgctgggagtttaccgtgctcacccgtgacccgcttcatgctcacatgatggcttcacctattggagaaagggcattctgccattgttagttttcagctcaccggtgggattctgggacagccttttgctcgttgtgccaaactgcaagaagggtagattatggttttgactctgacctcagccacaatcctgaactgatccaaattctatgagaagactgaaatctcgtgtctctaccaaagccttattttgttaaattagcacagttttcttacagcatctccatttttgcccaactttcttttagcccttactcccttttctacaacaaaacctgtctatccttaggtcctacaaagtcccttcctctctacaaatggctaagctcccctctggccatgttgctccattcacgtgtactcttttgttgcccacatgttcccaagttcaagaacacttgttttttttctgttctctgtgggttttcttgtcctgtcccctctccttgctcctggccacagagaagtacacacactgtggccactttcttgtacatagtcctttcctactctgcactatgaccgttcatctttaatgtgtaatttcccagcgaaatgtttaactcaggtgtgcattttgaagatgtctctatattattttatcttctgttagaaaaggaagggggataccagagtgtggaacaccccacagagttcccacgtgagctggggttctgcagactttgtggaggaacatcgtatgtggagtctccttctgtgggtctgtgtgtaaaactgtcacatgaaagccatcccaga

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