2024-03-29 18:18:26, GGRNA.v2 : RefSeq release 222 (Jan, 2024)
LOCUS NM_001102364 1544 bp mRNA linear ROD 23-MAR-2023 DEFINITION Rattus norvegicus claudin 6 (Cldn6), mRNA. ACCESSION NM_001102364 XM_001055688 XM_220202 VERSION NM_001102364.1 KEYWORDS RefSeq; RefSeq Select. SOURCE Rattus norvegicus (Norway rat) ORGANISM Rattus norvegicus Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus. REFERENCE 1 (bases 1 to 1544) AUTHORS Harris HJ, Davis C, Mullins JG, Hu K, Goodall M, Farquhar MJ, Mee CJ, McCaffrey K, Young S, Drummer H, Balfe P and McKeating JA. TITLE Claudin association with CD81 defines hepatitis C virus entry JOURNAL J Biol Chem 285 (27), 21092-21102 (2010) PUBMED 20375010 REFERENCE 2 (bases 1 to 1544) AUTHORS Krause G, Winkler L, Mueller SL, Haseloff RF, Piontek J and Blasig IE. TITLE Structure and function of claudins JOURNAL Biochim Biophys Acta 1778 (3), 631-645 (2008) PUBMED 18036336 REMARK Review article REFERENCE 3 (bases 1 to 1544) AUTHORS Nunes FD, Lopez LN, Lin HW, Davies C, Azevedo RB, Gow A and Kachar B. TITLE Distinct subdomain organization and molecular composition of a tight junction with adherens junction features JOURNAL J Cell Sci 119 (Pt 23), 4819-4827 (2006) PUBMED 17130295 REFERENCE 4 (bases 1 to 1544) AUTHORS Morita K, Furuse M, Yoshida Y, Itoh M, Sasaki H, Tsukita S and Miyachi Y. TITLE Molecular architecture of tight junctions of periderm differs from that of the maculae occludentes of epidermis JOURNAL J Invest Dermatol 118 (6), 1073-1079 (2002) PUBMED 12060405 REFERENCE 5 (bases 1 to 1544) AUTHORS Morita K, Furuse M, Fujimoto K and Tsukita S. TITLE Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands JOURNAL Proc Natl Acad Sci U S A 96 (2), 511-516 (1999) PUBMED 9892664 COMMENT PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CH473948.1. On or before Aug 24, 2007 this sequence version replaced XM_220202.3, XM_001055688.1. ##Evidence-Data-START## Transcript exon combination :: BC168250.1, BU671697.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## FEATURES Location/Qualifiers source 1..1544 /organism="Rattus norvegicus" /mol_type="mRNA" /db_xref="taxon:10116" /chromosome="10" /map="10q12" gene 1..1544 /gene="Cldn6" /note="claudin 6" /db_xref="GeneID:287098" /db_xref="RGD:1308837" exon 1..115 /gene="Cldn6" /inference="alignment:Splign:2.1.0" misc_feature 102..104 /gene="Cldn6" /note="upstream in-frame stop codon" exon 116..1544 /gene="Cldn6" /inference="alignment:Splign:2.1.0" CDS 132..791 /gene="Cldn6" /codon_start=1 /product="claudin-6 precursor" /protein_id="NP_001095834.1" /db_xref="GeneID:287098" /db_xref="RGD:1308837" /translation="
MASTGLQILGIVLTLLGWVNALVSCALPMWKVTAFIGNSIVVAQMVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVITLLIVLLGLLLYLAGAKCTTCVEDKNSKSRLVLISGVIFVISGVLTLIPICWTAHAIIQDFYNPLVADAQKRELGASLYLGWAASGLLLIGGGLLCCACSSGGTQGPSHYVARYSSPVPHSRGPSEYPSKNYV"
sig_peptide 132..194 /gene="Cldn6" /inference="COORDINATES: ab initio prediction:SignalP:4.0" misc_feature 141..641 /gene="Cldn6" /note="PMP-22/EMP/MP20/Claudin family; Region: PMP22_Claudin; cl21598" /db_xref="CDD:451326" ORIGIN
cccagctctgcgggcgccgccattaagcccctcctggtctcgcactcctaggcttggatatcgtgggtggccgaaccggacaggacgccctcggacaaagctgactgagcatttgccccctcaacctcatcatggcctctactggtctgcaaatcttggggattgtcctgaccctgcttggctgggtcaacgccctggtgtcctgtgccctgccgatgtggaaggtgaccgccttcatcggcaacagcatcgttgtggcccagatggtgtgggaggggctatggatgtcctgtgtggtccagagcactggtcagatgcagtgcaaggtgtacgactcgctgctggcgctgccccaggacctgcaggctgccagagccctctgtgtcatcaccctcctcattgtcctgcttggcctactcctgtaccttgccggagccaagtgcactacctgtgtggaagacaagaattccaagtctcgtctggtgctcatctctggtgtcatcttcgtcatctccggggtcctgaccctcattcccatctgctggactgcccacgccatcatccaggacttctacaaccccttggtcgcagacgctcaaaagcgagagctaggggcctccctctacctgggttgggccgcctcaggccttttgctgataggtggagggctgctatgctgcgcctgctcttctggagggacccagggacccagccattatgtggcccgctattcttcgcctgtcccacattctcggggaccctccgaatacccctccaagaattatgtctgatgcccactggggagtgaggctctactggccagagaacctgagctgagccgtgagaaatgatgtggggtagtttttggggtttgtcttgttccttgttttccttttgcaatgctgggtatgaaacctggggccccgcatatttggtaggcaagcactccacagtgagctgtgtggtaccctgccccctagggttggttccacctgtttttgagacaggctctccctaatggcgctctgactgacctccagctctcgttttttttttttttttgtttgtttgtttttttttcctgtctcaccctgagtccgaactccgcctatcgctccgttactggcatttctcgcttttacctactgtagctggagggatttgaccctgagttcctgtgtctttattcattctggggatctactgtgcaaagtgttttaaggctgcctgtgaatctggcctttgcgattctcaaaatggcttgtcccgagagttcctgctgtggctggaggtaactcacaggacagacacacccgctcctggtcaaactcttcccagtcctggaagggcaggtgataatttacctaagaattttcaactcagtcttccaacctttggcccctgaatcccatcaccaaggttactgtgtactctccccacatacggtcccagctgtgctgtagaccctcctcccccttacctctaaccttgcacatttccctgcccacacaatgttttacttaataaaacatgatttttttttt
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Creative Commons Attribution 4.0 International License (CC BY 4.0).
If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596.
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