LOCUS       NM_001101002            6320 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus POU class 6 homeobox 2 (Pou6f2), mRNA.
ACCESSION   NM_001101002 XM_001055787 XM_001055843 XM_039096067
VERSION     NM_001101002.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6320)
  AUTHORS   Yoshida,S., Ueharu,H., Higuchi,M., Horiguchi,K., Nishimura,N.,
            Shibuya,S., Mitsuishi,H., Kato,T. and Kato,Y.
  TITLE     Molecular cloning of rat and porcine retina-derived POU domain
            factor 1 (POU6F2) from a pituitary cDNA library
  JOURNAL   J Reprod Dev 60 (4), 288-294 (2014)
   PUBMED   24804940
  REMARK    GeneRIF: expressed in the stem/progenitor cells of the rat
            pituitary primordium as well as the diencephalon and retina
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000017.1.
            
            On or before Apr 8, 2021 this sequence version replaced
            XM_039096067.1, NM_001101002.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643293.72163.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-263               JAXUCZ010000017.1  51167772-51168034
            264-435             JAXUCZ010000017.1  51170067-51170238
            436-527             JAXUCZ010000017.1  51294361-51294452
            528-756             JAXUCZ010000017.1  51297562-51297790
            757-1133            JAXUCZ010000017.1  51436197-51436573
            1134-1274           JAXUCZ010000017.1  51525678-51525818
            1275-1481           JAXUCZ010000017.1  51548905-51549111
            1482-1650           JAXUCZ010000017.1  51565106-51565274
            1651-1819           JAXUCZ010000017.1  51574477-51574645
            1820-6320           JAXUCZ010000017.1  51577855-51582355
FEATURES             Location/Qualifiers
     source          1..6320
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17q11"
     gene            1..6320
                     /gene="Pou6f2"
                     /note="POU class 6 homeobox 2"
                     /db_xref="GeneID:681092"
     exon            1..263
                     /gene="Pou6f2"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    228..230
                     /gene="Pou6f2"
                     /note="upstream in-frame stop codon"
     exon            264..435
                     /gene="Pou6f2"
                     /inference="alignment:Splign:2.1.0"
     CDS             270..2324
                     /gene="Pou6f2"
                     /note="retina-derived POU-domain factor 1"
                     /codon_start=1
                     /product="POU domain, class 6, transcription factor 2"
                     /protein_id="NP_001094472.2"
                     /db_xref="GeneID:681092"
                     /translation="

MIAGQVSKPLLSVRSEMNAELRGEDKAATSDSELNEPLLAPVESNDSEDTPSKLFGARGNTVLPEPGTPDQHQASQTHPSFPVGPQPLLTAQQLASAVAGVMPGGPPALNQPILIPFNMAGQLGGQQGLVLTLPTANLTNIQGLVAAAAAGGIMTLPLQNLQATSSLNSQLQQLQQLQLQQQQQQQQPPPPPTSQHPQPASQAPAQSQQPQSQPTPPHQPPPASQQLPAAPAQLPQATQPQQHQPHSHPQNQNQSSPTQQSSSPPQKPTPSPGGHSLPSPLTPPNPLQLVNNPLASQAAAAAAAMGSIASSQAFGNALSSLQGVTGQLVTNAQGQIIGTIPLMPNPGPSSQAASGTQGLQVQPITPQLLTNAQGQIIATVIGNQILPVINTQGITLSPIKPGQQLHQSSQTSVGQAGTQGNLLHLAHGQASTSQSPVRQASSSSSSSSSSSALSVGQLVSNPQTAAGEVDGVNLEEIREFAKAFKIRRLSLGLTQTQVGQALSATEGPAYSQSAICRHTILRSHFFLPQEAQENTIASSLTAKLNPGLLYPARFEKLDITPKSAQKIKPVLERWMAEAEARHRAGMQNLTEFIGSEPSKKRKRRTSFTPQALEILNAHFEKNTHPSGQEMTEIAEKLNYDREVVRVWFCNKRQALKNTIKRLKQHEPTSAVPLEPLADSPEENC"

     misc_feature    1677..2006
                     /gene="Pou6f2"
                     /note="Pou domain - N-terminal to homeobox domain; Region:
                     Pou; cl22952"
                     /db_xref="CDD:473999"
     misc_feature    2070..2240
                     /gene="Pou6f2"
                     /note="Region: Homeodomain; pfam00046"
                     /db_xref="CDD:459649"
     exon            436..527
                     /gene="Pou6f2"
                     /inference="alignment:Splign:2.1.0"
     exon            528..756
                     /gene="Pou6f2"
                     /inference="alignment:Splign:2.1.0"
     exon            757..1133
                     /gene="Pou6f2"
                     /inference="alignment:Splign:2.1.0"
     exon            1134..1274
                     /gene="Pou6f2"
                     /inference="alignment:Splign:2.1.0"
     exon            1275..1481
                     /gene="Pou6f2"
                     /inference="alignment:Splign:2.1.0"
     exon            1482..1650
                     /gene="Pou6f2"
                     /inference="alignment:Splign:2.1.0"
     exon            1651..1819
                     /gene="Pou6f2"
                     /inference="alignment:Splign:2.1.0"
     exon            1820..6320
                     /gene="Pou6f2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

gaaaaacaacaaacacacagggagaaattctggggaaatttgagaattgcccacctcctttgtcttttgtcagtctctctcttcacctcccaatgccaagtgctccaaaatccagccaacaaacccagtgcctgggatactaatctatcaccgtaaatttagattgacaatactatgggtcgaccgcattgattacattgattctatttcaaatatttacaatacactgagacaagcctaatctattttctaaagagttcaaggatccaatgatagctggacaagtcagtaagcccttgctgtcagtgcggagtgaaatgaatgcggagttgagaggtgaggacaaggctgctacttcagacagcgagctgaatgagcccctgcttgcgcccgtggaatcaaatgacagcgaggacactcccagcaagctcttcggggccagaggaaacacagtcctaccagaaccaggaactcctgaccagcaccaggccagtcagacccatccctcctttccagttggaccacagcctcttctaacggcacagcagttagcctctgctgtggccggggtgatgccgggaggccccccagccctcaatcagcctatcctcatccccttcaacatggcgggacaactaggtggtcagcaaggcctggtcctcacactgcccaccgcgaatctcacaaacatccaagggctggtagcggcagctgcagctggaggcattatgactctgccattgcaaaatttacaagctacctcatccctgaactcccagctgcaacagctccagcaactccagctccagcagcaacagcagcagcaacaaccacctcctccaccaaccagccagcacccacagccagcctcacaggcgcccgcacagtctcagcagccgcagtcccagcccaccccgcctcaccagccaccacctgcttcacagcagttgccagctgccccagctcagctgccgcaggctactcagcctcaacagcatcaacctcattcccatccccagaaccagaaccagtcgtctccaacccagcagagctcaagcccccctcagaaacccaccccatctccaggaggacatagccttccgtcaccactcacaccgcctaaccctctacagctggttaataatcctctagcaagtcaggccgccgctgcagcagcagccatgggctccatagcaagctcacaggcctttggcaatgccctctccagccttcagggggtcacaggtcaactagttactaatgcacaaggacagattattgggaccattccactgatgcctaacccagggccatcgagtcaagcagcaagtggcactcagggccttcaagtacagcctatcacaccccagctcctaaccaatgcccagggccaaatcattgccacggtcatcggaaaccagatcttgcctgtgatcaatacccagggtattaccctgtcccccatcaagccaggccagcagcttcaccaatcttcccagacatcagttggtcaagcaggcacccaaggcaacctcctgcacctggctcatggccaagcatccacctctcaaagtccggtgcgacaggcttcctcctcctcctcttcatcctcctcttcttcagctttgagcgtgggccagttagtcagcaatcctcaaacggcagcgggtgaggtggacggggttaatctggaggagatccgagaatttgccaaagcttttaaaatccgacgcctgtcccttggcctgacacagactcaggtgggacaagccctcagtgccacagagggccctgcatacagccagtcggccatctgcagacacaccatcctgagaagccactttttcctaccacaggaagcccaagagaacactatagctagcagtctgacagccaaactgaaccctggccttttgtatcctgccaggtttgaaaagctggacatcacccctaaaagtgcccagaagattaagccggtgcttgagcggtggatggctgaggctgaggcccgccatcgagcaggtatgcagaatctcacggagtttattgggagtgagccatccaaaaagcgcaagcggcgcacctccttcacaccccaggcccttgagatcctcaatgcccactttgagaagaacacacacccctcagggcaggaaatgaccgagattgctgagaagctaaactatgaccgggaagtagttagagtttggttctgcaataagagacaagctctgaagaacacaatcaaacgtttaaagcagcacgagcccacctctgcggtccccctggaacccttagcggactctccggaagaaaactgttagacacaccgttcatgatcagaaggaagcatctcagaaactgagcattaccccaagtctccacaaaaaagaaagaaaaaagaagaaaaaagaatttaaagacacccccagtcatcatctctcttgtatgtaaaagactaaaaacaaaaactaccaagtgggcagaatggtttatacatgtctgttggttttccaaaaggaaaaaaaaaggagagagaaattttaaatttttaaacaagaaaaaataccacatgaaggagtatgtggtaggatcattcgctccccccacctgtctccctaaagccagttttttaaaagcaaaccaaataaccacttacttttttctgtacgtgatgaaaatgtgaacaccttttaaggaaaaaggaaaaaaaactaaaccaaaaaaaaaaaaaaaaaaagaacaaaagcaaaaaaaccgccaacacaaacttgtatctgttcaaagcgaatgcaagcctgccacctggaggagtgactgcaacccttcagggactaagtgctgatcactgcaaaccctatttaccaaagtcggaaacactgcaaatgctactgctcgtctactcgcctctgcgtgaagagttatgttatgagtttttacatgtgtaccaacaggaaagtggaagcccgctttctcccatctttcttgcctgatgtctgtgccaccacggcggatgctattgttgggagcattctctagggctcactgtctacaatttgcttcttagcagatgaagtagcttcctcttttctttctttctttttttgttattgtttttgttttctgaattgtgtcatttccttttttgttttatttttggcgggtggtggggtggagaaacaacctggattgtgtgccaaagccttcgtggctttctttcactatgagttgtaggtttgagagagaaaatggagttcacacttccctttcttccctattgctccatttccctttcctgtggttccggggaatcttctggaagatggcagaagtgggaagaatggtttctttcccactccaatcctgcagaaacgcaggagacaatccaggataactaagtctgtctgctgaatgactgtcaacactggcagaggctgtaactgctcacggttcacaccagagattgggatttttctcggtctactagccacatatgtggagagctgatacaaattaattctgtaatataaacatacgctgcacatatggttcaatacttaaacctgtgttatgcttctgttcaaagcaaattctctaagaagtctatagccaaagaaaagtctcaagatttcagtcagtacacacgcacacaagcacgtccatgctcattcgcctcacacacagagagagaccacaaaagatgatggtgacctagattgttaggggctgttgagtgtcctgttaacctcgtcttttctgctacttgtttcatcaaacagtgttggcagacatttggagctggggtacatctgttcttgggatatatacatggcataaaaaggtgacaggcaaattgaagcaagtggaactaggctctggcttcttgacaaagaagtttagcaacaaaggctctccaataaaggaaaaatagacaagtagcttataaaacacctcagaagagccttccccattagcatattaattcactttcaaaagagcttccccaaggcatgagccacgagatccaagaaggccacagaatgaaaggcaaagaaacccttggagcctgttaatgttttcaccctggtgagggcagagagttctatcaaagcaggtaagaaccatcaacgtagatactcatgagtagttaaaaagcatgctcgtgtactgtctagaggcaaatcatgaaagggaaaaagaaaccccacctccagttgcccagttggttacaaagaccatcttgtatcccctagcaagctctcccaagcaggggttctagtttttttttctgttggctcctttgctggtaacaaaaatgggacagtaaaatagtccctcagatgcaatcataaatcagcaatcataaaactcccaccaaggaaactaaataataattctggacatagagtcattaataacagtgtctccatgccactagtctgattctaattggaccacaaccagcccgattagtgccaacaacatcatggtagcatttcacaactgcaaagactgaagaaataccagcaacccagaaaccgaaactttattgattaaaacagattttgtattctcctaggacctgctacaaattccatcaagaaaaactccccaagaagagacgctaacaagataacataggacggatgctaaatgtttaaaatctgaaccggaagcaggcacatgaggcctgctcagttctgaggtctatgattgggagagcatagctagaatagtaaaaatataaaataaaactaatcacccagagtagaacaaaaaagaagtgaattcatcccatggttgtaaaactattcacatgcagtgatttttttatagttttataattttgtattgttttataaattatttatatagtgttgtaatgcttcttatattgattttttactgatgaattttttgctacaaggcaaaaaaaaaagatgcctgaacagattcttaggaatataaactatacttgggaacacataagccttcaggaccacacctactgcttaattttattagatatttcttatttcctctggtaaagaacttcatatgccaataacatctaagtgtcttttatgtttccatgaactgaaggttaaggttgctaccaacaaaaagtaaaagccactttgggcaaatgtgattgtatttcaagcttctgtgtctttctcacacattttaaaaattgttgtcatctccattttcttcatcattgatgagacatgacagccgatattgtattttacacttgcttgtggaggttgttttctctttcaaccaaaaagatattttgagtagttaaaagtttcacttgcctttgcaagttttgaactctttctgtcgtgaacacacagtcacacacacacacacacacacacacacacacacacacacacaccacaaaagagaacaaaaaaaaaaaaaaacaaaggaaaaccaagagctgggagaggcagaacaaacaagtagaggcatatcaaagaactcaagctgtaaccaaaaagaaatccaattgcctttgctctcttctctacgctggaccaaagctcagtacgtgtaggaatatgcacattgtgtagatatggctaaatgttgctgacaatcttgcaatactaaactgttcctattttaagaaaaacaaatcacaaactgctcatcaatgttttacctcagcactctacttgtacccagttaacgatcaagcataaaaacaacggagaaaaaggaaattgattttcatttccatgtctgactgtaaaatcagtttggataatattttgtaatgagcttttttgtcatgtgacttgcttgtcttcaacttgcaattctgtgaggcacattggcttatttgttgttgaaaagtgttttttttttaaataccttgaagttttgatttattatttcatcctctgtgctgtgatctagactggtcaccagggtcacttaatgaagcgctgcaaaggaatctgcttctccatgcctggggcaggcagcaggagagagagcaggaaactagactgggttgttctggaaaaaaaaatcatgccgacaagacattgacatgatagactcgtgaccaagaagccaaactggatattgaaaagctccttacttgttctaacattgaaaccaaagctgacttatctgcacaggttgctaaatgtttaaaaaataaaataaaataaaaactgtccttaatctagagcaatatctgtatggtccgtaaagctgcactttgtgtatttctgaacagcttcagatctgtcacttttaatttgtaccatgaaaaataaagacttgtttgacatgaa

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