LOCUS       NM_001090563            1086 bp    mRNA    linear   VRT 22-MAY-2022
DEFINITION  Xenopus laevis distal-less homeobox 2 L homeolog (dlx2.L), mRNA.
ACCESSION   NM_001090563
VERSION     NM_001090563.2
KEYWORDS    RefSeq.
SOURCE      Xenopus laevis (African clawed frog)
  ORGANISM  Xenopus laevis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae;
            Xenopus; Xenopus.
REFERENCE   1  (bases 1 to 1086)
  AUTHORS   Papalopulu N and Kintner C.
  TITLE     Xenopus Distal-less related homeobox genes are expressed in the
            developing forebrain and are induced by planar signals
  JOURNAL   Development 117 (3), 961-975 (1993)
   PUBMED   8100768
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from L09728.1.
            
            On Sep 24, 2016 this sequence version replaced NM_001090563.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: L09728.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00012419 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1086              L09728.1           2-1087
FEATURES             Location/Qualifiers
     source          1..1086
                     /organism="Xenopus laevis"
                     /mol_type="mRNA"
                     /db_xref="taxon:8355"
                     /chromosome="9_10L"
                     /map="9_10L"
     gene            1..1086
                     /gene="dlx2.L"
                     /gene_synonym="dll4; dlx2; tes-1; tes1; X-dll2; X-dll4;
                     Xdll4"
                     /note="distal-less homeobox 2 L homeolog"
                     /db_xref="GeneID:399264"
                     /db_xref="Xenbase:XB-GENE-852896"
     exon            1..550
                     /gene="dlx2.L"
                     /gene_synonym="dll4; dlx2; tes-1; tes1; X-dll2; X-dll4;
                     Xdll4"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    25..27
                     /gene="dlx2.L"
                     /gene_synonym="dll4; dlx2; tes-1; tes1; X-dll2; X-dll4;
                     Xdll4"
                     /note="upstream in-frame stop codon"
     CDS             226..1083
                     /gene="dlx2.L"
                     /gene_synonym="dll4; dlx2; tes-1; tes1; X-dll2; X-dll4;
                     Xdll4"
                     /function="putative transcription factor"
                     /note="putative transcription factor DLL4; XDLL-4"
                     /codon_start=1
                     /product="homeobox protein DLL-4"
                     /protein_id="NP_001084032.1"
                     /db_xref="GeneID:399264"
                     /db_xref="Xenbase:XB-GENE-852896"
                     /translation="

MTGVFDSLAADMHSNHMPSSSYHSLHKSQESPTLPVSTATDSSYYTNQQQQQHCGAVSPYGQLGSYQFHGAAINGISYSTKSYDLSYTGSYSSYGPYGTSPSPPHNDQEKEDCEPEVRMVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGVTQTQVKIWFQNRRSKFKKMWKSGEIPSDQLPVGSESSPCSSPSASTATWDFGPHQRLQGATNGSALQSSNSASSPSPFLSNYSWYQTSNSAPHLQSNPLLQQHHLHHHPPAPISAGTIF"

     misc_feature    274..366
                     /gene="dlx2.L"
                     /gene_synonym="dll4; dlx2; tes-1; tes1; X-dll2; X-dll4;
                     Xdll4"
                     /note="propagated from UniProtKB/Swiss-Prot (P53775.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    310..546
                     /gene="dlx2.L"
                     /gene_synonym="dll4; dlx2; tes-1; tes1; X-dll2; X-dll4;
                     Xdll4"
                     /note="Homeobox protein distal-less-like N terminal;
                     Region: DLL_N; pfam12413"
                     /db_xref="CDD:432536"
     misc_feature    511..570
                     /gene="dlx2.L"
                     /gene_synonym="dll4; dlx2; tes-1; tes1; X-dll2; X-dll4;
                     Xdll4"
                     /note="propagated from UniProtKB/Swiss-Prot (P53775.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    order(607..621,625..627,676..678,694..696,733..735,
                     739..744,751..756,760..768,772..777)
                     /gene="dlx2.L"
                     /gene_synonym="dll4; dlx2; tes-1; tes1; X-dll2; X-dll4;
                     Xdll4"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238039"
     misc_feature    613..774
                     /gene="dlx2.L"
                     /gene_synonym="dll4; dlx2; tes-1; tes1; X-dll2; X-dll4;
                     Xdll4"
                     /note="Homeobox domain; Region: Homeobox; pfam00046"
                     /db_xref="CDD:425441"
     misc_feature    order(613..615,622..624,742..744,751..756,763..765)
                     /gene="dlx2.L"
                     /gene_synonym="dll4; dlx2; tes-1; tes1; X-dll2; X-dll4;
                     Xdll4"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:238039"
     misc_feature    787..939
                     /gene="dlx2.L"
                     /gene_synonym="dll4; dlx2; tes-1; tes1; X-dll2; X-dll4;
                     Xdll4"
                     /note="propagated from UniProtKB/Swiss-Prot (P53775.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     exon            551..735
                     /gene="dlx2.L"
                     /gene_synonym="dll4; dlx2; tes-1; tes1; X-dll2; X-dll4;
                     Xdll4"
                     /inference="alignment:Splign:2.1.0"
     exon            736..1086
                     /gene="dlx2.L"
                     /gene_synonym="dll4; dlx2; tes-1; tes1; X-dll2; X-dll4;
                     Xdll4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

gcggtcgtgagcgattactccccctgagcttgtgtagcgacccaacccaccagctgcggagaacatgcgtccagcgtcctcccaccgcccggcccgtcgctcctgatcgctgctcccttgtctacttggtttattgaaagcgattgcattatagtttttggtgtctctcccgagcctgttgcagacccttcaacctttgctgtgtactccacagcccctaatactatgaccggagtgtttgacagcttggcagcagatatgcattccaaccacatgccctccagcagttaccacagtctgcacaagtcgcaggaatccccgacattgccggtgtctactgccacggacagcagctactacaccaaccaacagcagcagcagcactgcggggcagtctctccttatgggcagctcggatcctatcagttccatggcgctgccatcaatgggatttcttattcgaccaagtcgtacgatctgtcatacactggctcgtacagctcgtatgggccctatgggacaagtccttcccctcctcacaacgaccaggagaaggaagactgcgagcccgaggtcaggatggtcaatgggaagccgaagaaagtgcgcaagccccgcaccatctattccagtttccagctggcggccctccagcggcgatttcagaaaacccaatacctggcactgcccgagagagcggaactggcagcctcgctaggcgtgacccagacacaggtgaagatctggttccagaaccgccgctctaaattcaagaagatgtggaagagcggggagatcccgtcggatcagctccctgtaggcagcgaatcttccccctgtagctccccttctgcatctacagccacctgggacttcgggccgcaccagcggttgcagggagcaactaatgggtctgcccttcagagctccaattctgcctccagtcccagcccttttctgagcaactattcctggtatcaaacttccaattctgccccccacctccagtctaacccgttacttcaacagcatcatctccaccatcatccccccgctccaatatccgcagggaccatcttctagaaa

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