LOCUS       NM_001090326            1164 bp    mRNA    linear   VRT 24-MAY-2021
DEFINITION  Xenopus laevis NK1 homeobox 2 L homeolog (nkx1-2.L), mRNA.
ACCESSION   NM_001090326 NM_001090327
VERSION     NM_001090326.2
KEYWORDS    RefSeq.
SOURCE      Xenopus laevis (African clawed frog)
  ORGANISM  Xenopus laevis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae;
            Xenopus; Xenopus.
REFERENCE   1  (bases 1 to 1164)
  AUTHORS   Kurata T and Ueno N.
  TITLE     Xenopus Nbx, a novel NK-1 related gene essential for neural crest
            formation
  JOURNAL   Dev. Biol. 257 (1), 30-40 (2003)
   PUBMED   12710955
REFERENCE   2  (bases 1 to 1164)
  AUTHORS   Klein SL, Strausberg RL, Wagner L, Pontius J, Clifton SW and
            Richardson P.
  TITLE     Genetic and genomic tools for Xenopus research: The NIH Xenopus
            initiative
  JOURNAL   Dev. Dyn. 225 (4), 384-391 (2002)
   PUBMED   12454917
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB103111.1.
            
            On Sep 23, 2016 this sequence version replaced NM_001090326.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB103111.1, BC169870.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN04111056, SAMN04285344
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1164              AB103111.1         3-1166
FEATURES             Location/Qualifiers
     source          1..1164
                     /organism="Xenopus laevis"
                     /mol_type="mRNA"
                     /db_xref="taxon:8355"
                     /chromosome="7L"
     gene            1..1164
                     /gene="nkx1-2.L"
                     /gene_synonym="nbx; nkx1-1.1; nkx1-2; nkx1.1"
                     /note="NK1 homeobox 2 L homeolog"
                     /db_xref="GeneID:399122"
                     /db_xref="Xenbase:XB-GENE-866592"
     exon            1..320
                     /gene="nkx1-2.L"
                     /gene_synonym="nbx; nkx1-1.1; nkx1-2; nkx1.1"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    104..106
                     /gene="nkx1-2.L"
                     /gene_synonym="nbx; nkx1-1.1; nkx1-2; nkx1.1"
                     /note="upstream in-frame stop codon"
     CDS             161..928
                     /gene="nkx1-2.L"
                     /gene_synonym="nbx; nkx1-1.1; nkx1-2; nkx1.1"
                     /note="NK1 homeobox 1, gene 1; NK-1 related homeobox
                     protein Nbx"
                     /codon_start=1
                     /product="NK1 homeobox 2 L homeolog"
                     /protein_id="NP_001083795.1"
                     /db_xref="GeneID:399122"
                     /db_xref="Xenbase:XB-GENE-866592"
                     /translation="

MGMLDCDPEEEKHAPGQKHLHTPFSIADILNHAKMQKVEEGIKEPDINDEGQTGMTNVRTRMTSESMVSEIENGAGTSPGLQANEPEELPEKEENQQPQNLPCATDCKPRRARTAFTYEQLVALESRFRSSRYLSVCERLSLALTLHLTETQVKIWFQNRRTKWKKQQPTGSWEGRGCSIQNCPTIPGPRINPPLPNYPCTTHISHIGAGTNHLSPFPGIFFSPPSTSFGLSPTGATYPQFIGSSSFTSYYSPPL"

     misc_feature    order(488..502,506..508,557..559,575..577,614..616,
                     620..625,632..637,641..649,653..658)
                     /gene="nkx1-2.L"
                     /gene_synonym="nbx; nkx1-1.1; nkx1-2; nkx1.1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238039"
     misc_feature    order(494..496,503..505,623..625,632..637,644..646)
                     /gene="nkx1-2.L"
                     /gene_synonym="nbx; nkx1-1.1; nkx1-2; nkx1.1"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:238039"
     misc_feature    497..655
                     /gene="nkx1-2.L"
                     /gene_synonym="nbx; nkx1-1.1; nkx1-2; nkx1.1"
                     /note="Homeobox domain; Region: Homeobox; pfam00046"
                     /db_xref="CDD:425441"
     exon            321..1143
                     /gene="nkx1-2.L"
                     /gene_synonym="nbx; nkx1-1.1; nkx1-2; nkx1.1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

catctgtgaacaggacagaaatctgccttcctccgtccacaggagtcctgcctgagcatcactgccagatctgtagttccccagtcagatccaggttgccagctgagggcatcaggtgcccggtggtttctggagcaagtgtgggactatctggagctacatgggaatgttagactgtgacccagaagaggaaaaacatgcccctggccagaaacacctccatactcccttctccatcgcagacatactgaaccatgcaaagatgcagaaagtcgaggaaggaatcaaggagcctgatatcaatgatgaaggacagacaggcatgacaaatgttagaactcgcatgacatctgaaagtatggtgtctgagatagaaaatggagcaggaacctctccaggcctacaagcaaatgaaccagaggagctgccagagaaagaggagaaccaacaaccccaaaacctcccgtgtgccaccgattgcaagccccgccgagcccgtactgccttcacttacgagcagcttgtggcccttgagagccgtttccgaagcagccgatacctgtcggtgtgtgagcggctgagcctagcgttaacccttcaccttacagagacacaagtgaagatctggttccagaaccgcagaaccaaatggaaaaagcagcagcctacaggaagctgggaagggagaggatgcagcatacaaaactgtcccaccatccctggtccccggattaacccacccctcccaaactacccctgtactacacacatctcccatattggtgctgggacaaaccatctctctcctttcccaggtatctttttttctcccccttccacatcctttggactaagccctacaggtgccacctatccccagtttataggttcatccagcttcacatcctattacagtcctcccctctgactccaggtgggtcctaccacttgatttctctcaatgacatcatgatatcatggaactgtactggatgatgcgactgtgaattcatagttatcatgctgggaacccaatataagcagtaaagtacccgcgggtacccgaacgctgcaggactctattgtaaattgtatttttattgtaaatgacatttaaaaaaaacatgactattgtacgaattaaaaaaaaaaaaaaaaaaaaaa

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