LOCUS       NM_001088604             930 bp    mRNA    linear   VRT 24-JUN-2020
DEFINITION  Xenopus laevis claudin 6, gene 2 S homeolog (cldn6.2.S), mRNA.
ACCESSION   NM_001088604 NM_001088605
VERSION     NM_001088604.1
KEYWORDS    RefSeq.
SOURCE      Xenopus laevis (African clawed frog)
  ORGANISM  Xenopus laevis
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae;
            Xenopus; Xenopus.
REFERENCE   1  (bases 1 to 930)
  AUTHORS   Klein SL, Strausberg RL, Wagner L, Pontius J, Clifton SW and
            Richardson P.
  TITLE     Genetic and genomic tools for Xenopus research: The NIH Xenopus
            initiative
  JOURNAL   Dev. Dyn. 225 (4), 384-391 (2002)
   PUBMED   12454917
REFERENCE   2  (bases 1 to 930)
  AUTHORS   Brizuela BJ, Wessely O and De Robertis EM.
  TITLE     Overexpression of the Xenopus tight-junction protein claudin causes
            randomization of the left-right body axis
  JOURNAL   Dev. Biol. 230 (2), 217-229 (2001)
   PUBMED   11161574
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC090246.1.
            
            On Jul 25, 2007 this sequence version replaced NM_001088605.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC090246.1 [ECO:0000332]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..930
                     /organism="Xenopus laevis"
                     /mol_type="mRNA"
                     /db_xref="taxon:8355"
                     /chromosome="9_10S"
     gene            1..930
                     /gene="cldn6.2.S"
                     /gene_synonym="cla; cldn4L1; cldna; Xcla; XclnA"
                     /note="claudin 6, gene 2 S homeolog"
                     /db_xref="GeneID:398209"
                     /db_xref="Xenbase:XB-GENE-17339342"
     misc_feature    49..51
                     /gene="cldn6.2.S"
                     /gene_synonym="cla; cldn4L1; cldna; Xcla; XclnA"
                     /note="upstream in-frame stop codon"
     CDS             55..699
                     /gene="cldn6.2.S"
                     /gene_synonym="cla; cldn4L1; cldna; Xcla; XclnA"
                     /note="transmembrane tight junction protein claudin;
                     claudin A"
                     /codon_start=1
                     /product="claudin 6, gene 2 S homeolog"
                     /protein_id="NP_001082073.1"
                     /db_xref="GeneID:398209"
                     /db_xref="Xenbase:XB-GENE-17339342"
                     /translation="

MASTGLQILGMAMSIIGWVGSIISCALPMWRVTAFIGNNIVVAQIIWEGLWMNCIVQSTGQMQCKVYDSMLALAQDLQAARALTVICILVALLAKFIGIVGAKCTNCIEDENTKAKVSMVSGIVFLVAGILMLIPVCWSANSIIRDFYNPLVVEAQKRELGAALYIGWASSALLLLGGGLLCCSCPKKNDAPYPARYTAPSCPPRSDYTSKNYV"

     misc_feature    64..558
                     /gene="cldn6.2.S"
                     /gene_synonym="cla; cldn4L1; cldna; Xcla; XclnA"
                     /note="PMP-22/EMP/MP20/Claudin family; Region:
                     PMP22_Claudin; cl21598"
                     /db_xref="CDD:451326"
ORIGIN      

atcgaattccccggggggcattgctgcagatctctccactctccactgtaaaagatggcttctactggtctccagatccttggcatggcaatgtccatcattggctgggtgggaagtataatctcgtgtgccttgcccatgtggagggtgactgccttcattgggaacaacatagtggtggcacagatcatctgggaaggcctgtggatgaattgtattgtgcagagtactgggcagatgcagtgcaaggtctatgactccatgttggctcttgctcaggacttgcaggctgcccgtgcccttactgtcatctgtatcctggtagccctgctagccaagttcattggtattgtgggagctaagtgcaccaactgcatagaagatgagaacaccaaggcaaaagtcagcatggtatccggcattgtcttcctggtggccggtatccttatgctcatccctgtctgctggtctgcaaacagcatcatccgtgacttctacaatcccctggtggtggaggctcagaagagagaactgggggctgccctgtatatagggtgggcttcctctgccttattactcctgggtggaggcctcctgtgctgttcttgccccaagaagaatgatgctccctacccagccagatacactgccccttcatgcccaccacggagtgactacaccagcaagaactatgtctgagggcataactggctggcttggacaattgtttttgactttttatatatatacagtatgggacatatttatcagttcctccagcaaatgtgtctgaactgcatatattgtgtgtttggaggggtgaatttgtggagattgtctgtttttggacttttagctgccttcagacatttttatataattttgtaacacttaaaataaaactttctatcccaaaaaaaaaaaaaaaaa

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