LOCUS       NM_001081622            2608 bp    mRNA    linear   MAM 27-JUN-2020
DEFINITION  Bos taurus distal-less homeobox 3 (DLX3), mRNA.
ACCESSION   NM_001081622 XM_001252693
VERSION     NM_001081622.1
KEYWORDS    RefSeq.
SOURCE      Bos taurus (cattle)
  ORGANISM  Bos taurus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia;
            Pecora; Bovidae; Bovinae; Bos.
REFERENCE   1  (bases 1 to 2608)
  AUTHORS   Degrelle SA, Murthi P, Evain-Brion D, Fournier T and Hue I.
  TITLE     Expression and localization of DLX3, PPARG and SP1 in bovine
            trophoblast during binucleated cell differentiation
  JOURNAL   Placenta 32 (11), 917-920 (2011)
   PUBMED   21937107
  REMARK    GeneRIF: study demonstrates the co-expression of DLX3, PPARG and
            SP1 in trophoblast binucleated cell (BNC)nuclei; this suggests a
            possible role of these transcription factors through BNC specific
            genes at the time of pre-placental differentiation
REFERENCE   2  (bases 1 to 2608)
  AUTHORS   Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D,
            Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Marcais G,
            Roberts M, Subramanian P, Yorke JA and Salzberg SL.
  TITLE     A whole-genome assembly of the domestic cow, Bos taurus
  JOURNAL   Genome Biol. 10 (4), R42 (2009)
   PUBMED   19393038
REFERENCE   3  (bases 1 to 2608)
  AUTHORS   Ezashi T, Das P, Gupta R, Walker A and Roberts RM.
  TITLE     The role of homeobox protein distal-less 3 and its interaction with
            ETS2 in regulating bovine interferon-tau gene
            expression-synergistic transcriptional activation with ETS2
  JOURNAL   Biol. Reprod. 79 (1), 115-124 (2008)
   PUBMED   18322277
  REMARK    GeneRIF: DLX3 has a central role in controlling IFNT gene
            expression by associating with ETS2 on the IFNT promoter.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC133325.1.
            
            On Feb 20, 2007 this sequence version replaced XM_001252693.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC133325.1, DV916479.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN03145412, SAMN03145413
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2608
                     /organism="Bos taurus"
                     /mol_type="mRNA"
                     /db_xref="taxon:9913"
                     /chromosome="19"
                     /map="19"
                     /breed="L1 Hereford"
     gene            1..2608
                     /gene="DLX3"
                     /note="distal-less homeobox 3"
                     /db_xref="BGD:BT18274"
                     /db_xref="GeneID:784366"
                     /db_xref="VGNC:VGNC:55816"
     exon            1..534
                     /gene="DLX3"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    174..176
                     /gene="DLX3"
                     /note="upstream in-frame stop codon"
     CDS             210..1073
                     /gene="DLX3"
                     /codon_start=1
                     /product="homeobox protein DLX-3"
                     /protein_id="NP_001075091.1"
                     /db_xref="BGD:BT18274"
                     /db_xref="GeneID:784366"
                     /db_xref="VGNC:VGNC:55816"
                     /translation="

MSGSFDRKLSSILTDISSSLSCHAGSKDSPTLPESSVTDLGYYSAPQHDYYSGQPYGQTVNPYTYHHQFNLNGLGGTGAYSPKSEYTYGTSYRQYGAYREQPLPAQDPVSVKEEPEAEVRMVNGKPKKVRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLTQTQVKIWFQNRRSKFKKLYKNGEVPLEHSPNNSDSMACNSPPSPALWDTSSHSTPAPARSQLPPPLPYSASPSYLDDPTNSWYHAQNLSGPHLQQQPPQPATLHHASPGPPPNPGAVY"

     misc_feature    288..530
                     /gene="DLX3"
                     /note="Homeobox protein distal-less-like N terminal;
                     Region: DLL_N; pfam12413"
                     /db_xref="CDD:432536"
     misc_feature    <534..905
                     /gene="DLX3"
                     /note="Homeodomain-containing transcription factor
                     [Transcription]; Region: COG5576"
                     /db_xref="CDD:227863"
     misc_feature    order(597..611,615..617,666..668,684..686,723..725,
                     729..734,741..746,750..758,762..767)
                     /gene="DLX3"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238039"
     misc_feature    603..764
                     /gene="DLX3"
                     /note="Homeobox domain; Region: Homeobox; pfam00046"
                     /db_xref="CDD:425441"
     misc_feature    order(603..605,612..614,732..734,741..746,753..755)
                     /gene="DLX3"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:238039"
     exon            535..725
                     /gene="DLX3"
                     /inference="alignment:Splign:2.1.0"
     exon            726..2582
                     /gene="DLX3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

gacgcgacgagaggcgcgccgcgaccgcccgaagacccgcgatggtctaagcgcccctcgaccgaccctccccagagacgctgccgggaaccctccccctcgccctccggacacacaaccccgcctcgtctcctccgcctcccccgagctcctgcccgcttcggcgttccggctgaggccagcccgggggtggtacggcgcccgccaggatgagtggctccttcgatcgcaagctcagcagcatcctcaccgacatctccagctcgctcagctgccatgcgggttccaaggactcgcccaccttgcccgagtcttccgtcactgacctgggctactacagcgctccccagcacgactactactcgggccagccctatggccagaccgtaaacccctacacctaccaccaccagttcaatctcaacgggcttggaggcacaggcgcttattcgcccaagtcggaatatacctacggaacctcctaccggcaatatggagcctaccgggagcagccgctgcccgctcaggacccagtgtccgtgaaggaggagccggaagctgaggtgcgcatggtgaacgggaagcccaagaaggtccgaaagccgcgcacgatctactccagttaccagttggccgccctgcagcgccgcttccagaaggcccagtacctggctctgcccgagcgcgcggagctggccgcgcagctgggcctcactcagacgcaggtgaaaatctggttccagaaccgccgttccaaattcaagaagctctataagaatggggaggttcccctggagcacagccccaacaacagcgattccatggcctgcaactcaccaccgtcacctgccctctgggacacctcttcccactctactccagcccctgcccgcagccagctgcccccgccactcccatacagtgcttcccccagctacctggacgaccccaccaactcctggtaccatgcacagaacctgagtggaccccacttacagcagcagccgcctcaaccagccaccctgcaccatgcctcccctgggcccccgcccaaccctggggctgtgtactgagcacctacccgtcctgaacctctcacgaaggaaccccgggaccaggcagaaggcgcctccgtcctagctgacactcaggaatcatcgaggagcacaggggaaaggacatccctttccccttcccttgccccttcttccagggacccaagagcttccagaggaaatttacatggaccaaggatgccccctgaacctcccactcactgcctagacactggggtgcccctccagatgtttgggcactccactccagctgggacagctgttccccttctgctccaagagcctggattggcttcaaatggctcatcaccttccagattctaaatcttagtactcggtccccagactggattccttgggtactggggagactgtggagtgtgcgcaggtcaggcttgggctgggctggggcaccaggcactgtggatcccaggacctgccaggcccaagatcctcccccaagccacctgtggttgtctccttcctgagcatcccctctgccaaaaagacattggaccgtgagactgggactcagggtggggacctcagcgagccctgccctgaacttctagccctcgtttaagatttgagggttacaccaaagaaaagccccaagtaagggaagcttttaatatttgtggctttagagagaagaattcaaggagcacctcgcctccccaactctggtcgaagaggaggggtgggtcccaggcagccttcccgaccacccatttcttctcccatgtacaggactttgcacaactttggtttcaaaagctgttgaaaaataggaagacaaagggcattgttaacagttaggaccaatctcccctgcgtgggcgcctctgctcacccccgcgcccccaccccgcctcttcccacctcttcctctcctccagtaagctggcgccaaaccccaaatctccaaggagacacaccaggaaagacaaacccccgaacaccccctttccggtggccttggaaacagattgttcccgccaagacagagaatgtcgggtgaggtgcacggtgttataactcggtacctttaggggtgagggggtggctggctgaaaggctggtagcactggctcttcctggcccagatgtccccccaaagctaactttcctccacccctgatgtggtcaaatatcgaagaagaggaggggtagaagactctagctatatatatagtatgtattttttttttaaagcaacagagagaagcagtctcctccctcctgtggtttcctatttatgtggccctttcctcctggatgtacctgcctgtgcgcagtgagctgagagaaacagagatgtgggctccggctggatttgggtttggtgggaggcgcaggcgcgaggagagacatggtggatctcaaagagtcccaccccagggggatgggaacgaagccagctcccaccctctcccagccttctcatttctgctttcttattggactcacctttatatataacattaataaaaaagaagaaaataaaaaaaaaaaaaaaaaaaaaaaaaaaa

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