GGRNA ver.2 Home | Help | Advanced search    Previous release (v1)

2020-03-31 04:45:24, GGRNA.v2 : RefSeq release 99 (Mar, 2020)

LOCUS       NM_001077674            2141 bp    mRNA    linear   ROD 20-OCT-2019
DEFINITION  Rattus norvegicus H2.0-like homeobox (Hlx), mRNA.
ACCESSION   NM_001077674 XM_001064868 XM_344184
VERSION     NM_001077674.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2141)
  AUTHORS   Bates MD, Dunagan DT, Welch LC, Kaul A and Harvey RP.
  TITLE     The Hlx homeobox transcription factor is required early in enteric
            nervous system development
  JOURNAL   BMC Dev. Biol. 6, 33 (2006)
   PUBMED   16854219
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2141)
  AUTHORS   Mikhalkevich N, Becknell B, Caligiuri MA, Bates MD, Harvey R and
            Zheng WP.
  TITLE     Responsiveness of naive CD4 T cells to polarizing cytokine
            determines the ratio of Th1 and Th2 cell differentiation
  JOURNAL   J. Immunol. 176 (3), 1553-1560 (2006)
   PUBMED   16424184
REFERENCE   3  (bases 1 to 2141)
  AUTHORS   Quinn LM, Johnson BV, Nicholl J, Sutherland GR and Kalionis B.
  TITLE     Isolation and identification of homeobox genes from the human
            placenta including a novel member of the Distal-less family, DLX4
  JOURNAL   Gene 187 (1), 55-61 (1997)
   PUBMED   9073066
REFERENCE   4  (bases 1 to 2141)
  AUTHORS   Hentsch B, Lyons I, Li R, Hartley L, Lints TJ, Adams JM and Harvey
            RP.
  TITLE     Hlx homeo box gene is essential for an inductive tissue interaction
            that drives expansion of embryonic liver and gut
  JOURNAL   Genes Dev. 10 (1), 70-79 (1996)
   PUBMED   8557196
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC127513.1.
            On or before Nov 15, 2006 this sequence version replaced
            XM_344184.3, XM_001064868.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC127513.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2689594, SAMEA2689598
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2141
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q26"
     gene            1..2141
                     /gene="Hlx"
                     /gene_synonym="Hlx1"
                     /note="H2.0-like homeobox"
                     /db_xref="GeneID:364069"
                     /db_xref="RGD:1311961"
     exon            1..905
                     /gene="Hlx"
                     /gene_synonym="Hlx1"
                     /inference="alignment:Splign:2.0.8"
     misc_feature    26..28
                     /gene="Hlx"
                     /gene_synonym="Hlx1"
                     /note="upstream in-frame stop codon"
     CDS             323..1753
                     /gene="Hlx"
                     /gene_synonym="Hlx1"
                     /note="homeobox protein HLX1; H2.0-like homeo box 1"
                     /codon_start=1
                     /product="H2.0-like homeobox protein"
                     /protein_id="NP_001071142.1"
                     /db_xref="GeneID:364069"
                     /db_xref="RGD:1311961"
                     /translation="
MFAAGLAPFYASNFSLWSAAYCSSAGPGGCSFALDPAAVKKPSFCIADILHAGVGEPGPAAEGLVGASAALTAHLGSVHPHASFQAAARSPLRPTPVVAPSEVPAGFPQRLSPLSAAYHQHLPQQPPTQQQQPQQQPPPPPRAGSLQPPTSGTRVVPHHSGSAPAPSSKDLKFGIDRILSAEFDPKVKEGNTLRDLTSLLTGGRPTGVHLAGLQPSAGQFFASLDPISEASAILSPLSSNPRNSVQHQFQDTFPGPYAVLTKDTMPQTYKRKRSWSRAVFSNLQRKGLEKRFEIQKYVTKPDRKQLAAMLGLTDAQVKVWFQNRRMKWRHSKEAQAQKDKDKEAGEKPSGGVPAEGEREERSPSRSEGEAESESSDSESLDMAPSDTERTEGTERSLHQTTVIKASAAGALITASSSASGSSFSFSSSSSLGSSNGSAGSASSLGSNCSELLPSHQPSVTSGPQSPEIAQVPLAGL"
     misc_feature    992..>1345
                     /gene="Hlx"
                     /gene_synonym="Hlx1"
                     /note="Homeodomain-containing transcription factor
                     [Transcription]; Region: COG5576"
                     /db_xref="CDD:227863"
     misc_feature    order(1130..1144,1160..1162,1211..1213,1229..1231,
                     1268..1270,1274..1279,1286..1291,1295..1303,1307..1312)
                     /gene="Hlx"
                     /gene_synonym="Hlx1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238039"
     misc_feature    order(1136..1138,1157..1159,1277..1279,1286..1291,
                     1298..1300)
                     /gene="Hlx"
                     /gene_synonym="Hlx1"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:238039"
     misc_feature    1148..1309
                     /gene="Hlx"
                     /gene_synonym="Hlx1"
                     /note="Homeobox domain; Region: Homeobox; pfam00046"
                     /db_xref="CDD:278475"
     exon            906..1085
                     /gene="Hlx"
                     /gene_synonym="Hlx1"
                     /inference="alignment:Splign:2.0.8"
     exon            1086..1270
                     /gene="Hlx"
                     /gene_synonym="Hlx1"
                     /inference="alignment:Splign:2.0.8"
     exon            1271..2116
                     /gene="Hlx"
                     /gene_synonym="Hlx1"
                     /inference="alignment:Splign:2.0.8"
ORIGIN      
ccctgtctccccggcttctgcggagtagcagaacgaggccgcgtccgccgcctcgccccagcgccgggcgatcgcctccatccaccggacggagagcttgcccgccgcgccgcctttcaagccaagccaggggcccaggccgtggcgggcggcgatcgggccctcgccacgtccctcggtggcgctagggctcccgggctggccctccgcttcggggcgagcggagaagcgaaagcagctcgggctgggctgggacaccgcctctccccgagcacccacccacttccccactcacccaagaccccgccgggatcctgccaggatgttcgcagccggcctggctcccttctacgcttccaactttagtctctggtcagccgcctactgctcctccgcgggcccgggcggctgctccttcgccttggacccggccgctgtcaagaaaccctctttctgcatcgcggacatcctgcacgccggcgtcggggagccgggacccgctgcagagggactggtgggggcctcggcagccctcaccgcacacttgggctccgtgcacccgcacgcttccttccaagctgccgccagatccccgctccgtcccaccccggtggtggcgccctcagaagtcccggctggattccctcagcggctgtctccgctctctgccgcctaccaccagcatctcccgcagcaaccaccaacgcagcaacagcagccgcagcaacagcccccgcctccaccccgggcgggctccctgcagccgccgacttcggggacgcgggtggtcccccaccatagcggctccgcccctgccccctccagcaaagacctcaaatttggtattgaccgaattttgtctgcagaatttgacccaaaagtcaaggaaggcaacactctgagagatctcacatcgctgctaactggtgggcggcccacaggggtgcatctggctggcctgcagccttcggcgggacagttcttcgcatctctagatcccattagcgaggcgtctgccatcctcagccccttaagctccaacccaagaaattctgttcaacatcaattccaagacacgtttccaggtccctatgctgtgcttaccaaggacaccatgccacagacgtacaagcggaagcgctcctggtcccgtgctgtcttttccaacctgcaaagaaaaggcctggagaagaggtttgagatccagaagtacgtgaccaaaccagatcgaaagcagctggcggccatgctgggcctcacggatgcacaggtgaaggtgtggttccagaaccggaggatgaagtggcggcattctaaggaggcgcaggcgcaaaaggacaaggacaaggaagcgggcgaaaagccttcgggcggagtccccgccgagggagaaagagaagagaggagccccagccgttccgagggcgaagccgagagcgagagcagtgactcggagtccctggacatggcccccagcgacacagaacggactgagggaacagagaggtccctgcaccaaactacagtcatcaaggcctcagccgcgggtgccctcatcacagccagcagcagcgcgagtgggagcagcttcagcttcagcagctccagcagcctgggtagcagcaacggcagcgcggggagcgccagcagccttggcagcaactgctcggagctgcttccctcgcaccagccctcagtcaccagcggtcctcaaagccctgagattgcccaggttccgcttgcaggtttatagactggaccgagggcatggcgtgtagcttccccaacactggctggagattgtgcctactttaagttggtggcaagggtcgccgagatgggagccggacgccgtgggcagcctctttggggttcatgccttttctcttgctgccaaggctccctaaggcccacaacccccttccccacaaagagtggagagttttaaggtccctggccaaagaaagaattcgactgttctccctacccaagcagctcacactgtgaagtgttcggtggaactgttcctctgagcaccaggggtcttggcgtaaggacaagctgcacttaggaggcctttaacttgtaaataaaatgtttactacggtttgtaaaaaaaaaaaaaaaaaaaaaaaaaaaaa
//

by @meso_cacase at DBCLS
This page is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).

If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596. [Full Text]