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2021-10-29 03:39:19, GGRNA.v2 : RefSeq release 207 (Jul, 2021)

LOCUS       NM_001047091            1657 bp    mRNA    linear   ROD 02-OCT-2017
DEFINITION  Rattus norvegicus homeobox B2 (Hoxb2), mRNA.
ACCESSION   NM_001047091 XM_001081296 XM_220894
VERSION     NM_001047091.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1657)
  AUTHORS   Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P,
            Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM,
            Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E,
            Kivioja T and Taipale J.
  TITLE     DNA-binding specificities of human transcription factors
  JOURNAL   Cell 152 (1-2), 327-339 (2013)
   PUBMED   23332764
REFERENCE   2  (bases 1 to 1657)
  AUTHORS   Prabagaran E, Hegde UC, Moodbidri SB, Bandivdekar AH and Raghavan
            VP.
  TITLE     Postnatal expression and androgen regulation of HOXBES2
            homeoprotein in rat epididymis
  JOURNAL   J. Androl. 28 (5), 755-771 (2007)
   PUBMED   17494099
  REMARK    GeneRIF: HOXBES2 expression could be regulated by androgens, and
            its expression level is closely associated with the postnatal
            development of the epididymis.
REFERENCE   3  (bases 1 to 1657)
  AUTHORS   Prabagaran E, Bandivdekar AH, Dighe V and Raghavan VP.
  TITLE     HOXBES2: a novel epididymal HOXB2 homeoprotein and its
            domain-specific association with spermatozoa
  JOURNAL   Biol. Reprod. 76 (2), 314-326 (2007)
   PUBMED   17065603
  REMARK    GeneRIF: We have identified and characterized a novel epididymal
            homeoprotein different from HOXB2 protein and hereafter referred to
            as HOXBES2, (HOXB2 homeodomain containing epididymis-specific sperm
            protein) with a probable role in fertilization.
REFERENCE   4  (bases 1 to 1657)
  AUTHORS   Florea L, Di Francesco V, Miller J, Turner R, Yao A, Harris M,
            Walenz B, Mobarry C, Merkulov GV, Charlab R, Dew I, Deng Z, Istrail
            S, Li P and Sutton G.
  TITLE     Gene and alternative splicing annotation with AIR
  JOURNAL   Genome Res. 15 (1), 54-66 (2005)
   PUBMED   15632090
REFERENCE   5  (bases 1 to 1657)
  AUTHORS   Samad OA, Geisen MJ, Caronia G, Varlet I, Zappavigna V, Ericson J,
            Goridis C and Rijli FM.
  TITLE     Integration of anteroposterior and dorsoventral regulation of
            Phox2b transcription in cranial motoneuron progenitors by
            homeodomain proteins
  JOURNAL   Development 131 (16), 4071-4083 (2004)
   PUBMED   15289435
REFERENCE   6  (bases 1 to 1657)
  AUTHORS   Manley NR, Barrow JR, Zhang T and Capecchi MR.
  TITLE     Hoxb2 and hoxb4 act together to specify ventral body wall formation
  JOURNAL   Dev. Biol. 237 (1), 130-144 (2001)
   PUBMED   11518511
REFERENCE   7  (bases 1 to 1657)
  AUTHORS   Medina-Martinez O, Bradley A and Ramirez-Solis R.
  TITLE     A large targeted deletion of Hoxb1-Hoxb9 produces a series of
            single-segment anterior homeotic transformations
  JOURNAL   Dev. Biol. 222 (1), 71-83 (2000)
   PUBMED   10885747
REFERENCE   8  (bases 1 to 1657)
  AUTHORS   Davenne M, Maconochie MK, Neun R, Pattyn A, Chambon P, Krumlauf R
            and Rijli FM.
  TITLE     Hoxa2 and Hoxb2 control dorsoventral patterns of neuronal
            development in the rostral hindbrain
  JOURNAL   Neuron 22 (4), 677-691 (1999)
   PUBMED   10230789
REFERENCE   9  (bases 1 to 1657)
  AUTHORS   Barrow JR and Capecchi MR.
  TITLE     Targeted disruption of the Hoxb-2 locus in mice interferes with
            expression of Hoxb-1 and Hoxb-4
  JOURNAL   Development 122 (12), 3817-3828 (1996)
   PUBMED   9012503
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from DQ399532.1.
            On or before Sep 7, 2006 this sequence version replaced
            XM_220894.4, XM_001081296.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DQ399532.1 [ECO:0000332]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1657
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Holtzman"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q26"
     gene            1..1657
                     /gene="Hoxb2"
                     /gene_synonym="Hoxbes2"
                     /note="homeobox B2"
                     /db_xref="GeneID:100361765"
                     /db_xref="RGD:2319509"
     misc_feature    209..211
                     /gene="Hoxb2"
                     /gene_synonym="Hoxbes2"
                     /note="upstream in-frame stop codon"
     CDS             218..1135
                     /gene="Hoxb2"
                     /gene_synonym="Hoxbes2"
                     /note="Hoxb2-like epididymal protein; homeo box B2-like;
                     homeobox protein Hox-B2"
                     /codon_start=1
                     /product="homeobox B2"
                     /protein_id="NP_001040556.1"
                     /db_xref="GeneID:100361765"
                     /db_xref="RGD:2319509"
                     /translation="
MGFMDKIYLTPKDMCILSTLLRCQPKITRGSKSTVSLQHLLESPTFAQSSFLRFTKTPRKCGSAVGFPRSPVNSRILLSVAHPWRAQSSLKINTPPLLLRXKIMGAXKNEMXGXTARGLPEAGGGGARRLRTAYTNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQHREPPDGEPACPGALEDTGDPVKEPAVSPGGPSASRAAWEACSHPPEVVPGALIAADPRPLSGGLKGAGAPSLAATARGGRAGPGHCQKCLPGAPDSLPSDLTSSRATPVSAIRRPLP"
     misc_feature    425..>778
                     /gene="Hoxb2"
                     /gene_synonym="Hoxbes2"
                     /note="Homeodomain-containing transcription factor
                     [Transcription]; Region: COG5576"
                     /db_xref="CDD:227863"
     misc_feature    order(599..613,617..619,668..670,686..688,725..727,
                     731..736,743..748,752..760,764..769)
                     /gene="Hoxb2"
                     /gene_synonym="Hoxbes2"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238039"
     misc_feature    order(605..607,614..616,734..736,743..748,755..757)
                     /gene="Hoxb2"
                     /gene_synonym="Hoxbes2"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:238039"
     misc_feature    608..766
                     /gene="Hoxb2"
                     /gene_synonym="Hoxbes2"
                     /note="Homeobox domain; Region: Homeobox; pfam00046"
                     /db_xref="CDD:278475"
ORIGIN      
gcccttccgatcctccctcctgactcccacccggcttaagggtctttttgtgttcacaggaaccaactgttctgagcaccacctatgaccatggcactttgcaagcatatgtcaagccaattgctaaggcaggcattcttgtacccattctagtgctgaggaaactgaggctcaggcagatgctcagttgacttgcccttcaagttaatagaggagcatgggatttatggacaagatttatctgacaccaaaggacatgtgtattctttccactctactaagatgccagccaaaaataacccgtgggtccaaaagtacagtgtctctgcaacatctgttggagtcccctacctttgcccaaagctcctttctaaggtttaccaagactcccagaaagtgtggttcagctgtgggcttcccccgctccccagttaattccaggattttattatcagttgcccatccctggagagctcaaagctctctgaaaataaacacaccaccactgctcctgaggnccaaaataatgggngcanaaaaaaatgaaatganaggggngacggcacgaggactgccggaggctggtggcggcggggcgcgcaggctgcgcacggcttacaccaacacacagctgctggaactggagaaggaattccactttaataagtacctgtgccggccacgccgcgtcgagatcgcagccttgctggatctcaccgaaaggcaggtcaaagtctggttccagaaccggcgcatgaagcacaagcggcagacgcagcaccgagagccgccggatggggagcctgcctgcccgggcgccctggaggacaccggcgaccctgtcaaggagcccgcggtcagcccgggcggcccctccgcctcgcgggcggcgtgggaagcctgctctcacccgccggaagtggtgccgggggccttaatcgccgcggacccccgacctttatccggtggcttaaaaggcgcgggcgcgccgagcctggctgcgactgcgcggggcgggcgggccggaccgggacattgccagaaatgtcttcccggagcgccagattcgcttccttccgacttaacttcttcgcgggcgactcctgtctcagctatccggaggcctctcccctagcctgcagggttctctcgacagcccccaggggaaaaggctccttctcgacctgaagaagtggtcgtgcgagacacggtagctggacgtctttccctaacccgtttcctcctcccggtcctttccacccccgcgctccttggtcatctactggaaaaatcgagcctctcctacccccagtcgcatagacttatgtgttttcctaaaattcaggtattactgaattaggtttaatccactccctttttttcttctaaaatattgggcactcgggcatcttttaaaattcacacagaaaaattccgtttggtagactccttccaatgaaatctcaggaataattaaactctagggggacttcttaaaaataactagaaggacttatttcctcttttttatgttttagactgtagataatttattaaaattctttaataataggaaaaggggaaagtatttattgtacattattttcatagattaaataaatgttctttataatacgaaaaaaaaaaaaaaaaaaaa
//

by @meso_cacase at DBCLS
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If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596. [Full Text]