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2021-10-17 14:44:33, GGRNA.v2 : RefSeq release 207 (Jul, 2021)

LOCUS       NM_001037774            2285 bp    mRNA    linear   ROD 02-OCT-2017
DEFINITION  Rattus norvegicus claudin 8 (Cldn8), mRNA.
ACCESSION   NM_001037774 XM_221709
VERSION     NM_001037774.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2285)
  AUTHORS   Molina-Jijon E, Rodriguez-Munoz R, Gonzalez-Ramirez R,
            Namorado-Tonix C, Pedraza-Chaverri J and Reyes JL.
  TITLE     Aldosterone signaling regulates the over-expression of claudin-4
            and -8 at the distal nephron from type 1 diabetic rats
  JOURNAL   PLoS ONE 12 (5), E0177362 (2017)
   PUBMED   28493961
  REMARK    GeneRIF: the participation of aldosterone (ALD), and the effect of
            spironolactone (SPL), a mineralocorticoid receptor antagonist, on
            the expressions of claudin-2, -4, -5 and -8, and occludin in
            glomeruli, proximal and distal tubules isolated from diabetic rats,
            was evaluated.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2285)
  AUTHORS   Krause G, Winkler L, Mueller SL, Haseloff RF, Piontek J and Blasig
            IE.
  TITLE     Structure and function of claudins
  JOURNAL   Biochim. Biophys. Acta 1778 (3), 631-645 (2008)
   PUBMED   18036336
  REMARK    Review article
REFERENCE   3  (bases 1 to 2285)
  AUTHORS   Fujita H, Chiba H, Yokozaki H, Sakai N, Sugimoto K, Wada T, Kojima
            T, Yamashita T and Sawada N.
  TITLE     Differential expression and subcellular localization of claudin-7,
            -8, -12, -13, and -15 along the mouse intestine
  JOURNAL   J. Histochem. Cytochem. 54 (8), 933-944 (2006)
   PUBMED   16651389
REFERENCE   4  (bases 1 to 2285)
  AUTHORS   Hu YH, Warnatz HJ, Vanhecke D, Wagner F, Fiebitz A, Thamm S, Kahlem
            P, Lehrach H, Yaspo ML and Janitz M.
  TITLE     Cell array-based intracellular localization screening reveals novel
            functional features of human chromosome 21 proteins
  JOURNAL   BMC Genomics 7, 155 (2006)
   PUBMED   16780588
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2285)
  AUTHORS   Ohta H, Adachi H and Inaba M.
  TITLE     Developmental changes in the expression of tight junction protein
            claudins in murine metanephroi and embryonic kidneys
  JOURNAL   J. Vet. Med. Sci. 68 (2), 149-155 (2006)
   PUBMED   16520537
REFERENCE   6  (bases 1 to 2285)
  AUTHORS   Morita K, Furuse M, Fujimoto K and Tsukita S.
  TITLE     Claudin multigene family encoding four-transmembrane domain protein
            components of tight junction strands
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 96 (2), 511-516 (1999)
   PUBMED   9892664
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC099804.1.
            On Dec 16, 2005 this sequence version replaced XM_221709.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC099804.1 [ECO:0000332]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2285
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q11"
     gene            1..2285
                     /gene="Cldn8"
                     /note="claudin 8"
                     /db_xref="GeneID:304124"
                     /db_xref="RGD:1308575"
     CDS             3..680
                     /gene="Cldn8"
                     /codon_start=1
                     /product="claudin-8"
                     /protein_id="NP_001032863.1"
                     /db_xref="GeneID:304124"
                     /db_xref="RGD:1308575"
                     /translation="
MATYALQMAALVLGGVGMVGTVAVTIMPQWRVSAFIESNIVVFENRWEGLWMNCMRHANIRMQCKVYDSLLALSPDLQASRGLMCAASVLSFLAFMTAILGMKCTRCTGEDENVKSRILLTAGIIFFITGLVVLIPVSWVANAIIRDFYNPLVDVAQKRELGEALYIGWTTALVLIAGGALFCCVFCCTERSNSYKYSVPSHRTTQRSFHAEKRSPSIYSKSQYV"
     misc_feature    15..548
                     /gene="Cldn8"
                     /note="PMP-22/EMP/MP20/Claudin family; Region:
                     PMP22_Claudin; cl21598"
                     /db_xref="CDD:304458"
     STS             15..611
                     /gene="Cldn8"
                     /standard_name="Cldn8"
                     /db_xref="UniSTS:259593"
     STS             79..324
                     /gene="Cldn8"
                     /standard_name="Cldn8"
                     /db_xref="UniSTS:259057"
     STS             83..549
                     /gene="Cldn8"
                     /standard_name="PMC99911P1"
                     /db_xref="UniSTS:273698"
     STS             1981..2099
                     /gene="Cldn8"
                     /standard_name="BI292090"
                     /db_xref="UniSTS:245145"
ORIGIN      
ccatggcaacctacgctcttcaaatggctgccctggtgcttggtggtgttggcatggtgggcacagtggctgtgacgatcatgcctcagtggagagtgtctgccttcatcgaaagtaacattgtcgtgtttgagaaccgctgggaaggtttgtggatgaactgcatgaggcatgccaacatcagaatgcagtgtaaggtctatgactccctgctggctcttagtccagacctccaggcatccagaggactgatgtgtgctgcgtccgtcctgtccttcttggctttcatgacagccatcctcggaatgaagtgcaccaggtgcaccggggaggacgagaacgtgaagagccgcatcttgctgacggctggaatcatcttcttcatcaccggcttggttgtgctcatccctgtcagctgggttgccaatgccatcatcagagacttctacaacccgctggtggatgtggcccaaaagcgcgagcttggtgaagccctctacataggctggaccacggcgctggtgctgatcgctggaggagcactgttctgttgcgtgttttgctgtactgaaaggagtaacagttacaagtactcggtaccatcccatcgcaccactcagaggagtttccacgccgaaaagagatccccgagcatatactccaaaagtcagtatgtgtagctgtgtgtgtatattttagctgtagctataaagcgaagctttataaatcactgaaccagccactattttatagaaatggaacccacagtgtttccatttacctttcttaactgcctcgtactcattacaggaaatacgcagcgtctatgattccataaatgattttagcagaatgaggtattatgcacactgcttcaattgttccagaaagcatagccatttgttttctaaaatggttcacgcggttcttcttttatcagtcactctaagacgacccatcgaaagactgttggtttaagctgcgatttctctgtgtcatggcattatacaagtaatgcgagtggcagttatagctcacacaaatagagacaggcttatgtggttctatttaaagtgaaatgccaatccatcaggctgaataaacagaactcagctattgcatttcaggggacctggggataaaaggaaagaaggctgatattaattgcctaaaaacagcttaaggattagtgcactctatttatagcaaaggttaaaatgaaggctttcatcattagtgtaagggaaactgaatggctttctgatcgcctgctttgcagcctccaggagttaaaaatcctgtcacctttatcctttatccacgtgccttttttttttctgattgtgttccttagtatcttttaaagtttaaagcagatattgtaacaaaatattttttttcttcagactacgtttgtaaggctgggctaacaagagagataaagcagtggtcttagaaaaattaacgttttcagaaaaatgactttaccttagcctttctctttagagaagaatgtattgtttttaaaatgaagtcacatcatataaaaggggccgttcaagtgctatttgtgcatacctttttgggaatttttctgtataaataagagaggaaaaagaatattttgtcatttacttaccccaaagaggtacaatccctccaaatccaaaaacttgtcctctttcaactcttgtcattcaatcaaagttgtcatttctgttctgttggaggtgatttcctctttttctatgtctttgctaagttttattaaagtgtggtatcactgtgtgtttcctcctaatttgagacaactattaaggtaataccaaatttcatatatatgacttttatattggtaaattgtatcttttataacaatatagcatttcttacatttacattctttttcattactttgcacaagtgtttaaaacttggcattgacaatttatgtttgaacatagatttcgtgttcattttttctggtgcggtgtaggatttaaatcaatttactttataatgacctgactcatgcattaatatttgattaatatattaataatactaagttctacttaggtccagtgaaatgtgtttgctgtaaatattgtgtatgtaatcatatttttaaaagttgtccatatgtatttcaacttctgagaattcgtttgaattaaaaacaaagctgaatgatttgggagtatgcaccatatttatgtgaagtatattattaaaactttgcaatactaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa
//

by @meso_cacase at DBCLS
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If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596. [Full Text]