GGRNA ver.2 Home | Help | Advanced search    Previous release (v1)

2021-10-17 15:40:32, GGRNA.v2 : RefSeq release 207 (Jul, 2021)

LOCUS       NM_001014096            1574 bp    mRNA    linear   ROD 01-FEB-2021
DEFINITION  Rattus norvegicus claudin 18 (Cldn18), mRNA.
ACCESSION   NM_001014096 XM_236603
VERSION     NM_001014096.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1574)
  AUTHORS   Linares GR, Brommage R, Powell DR, Xing W, Chen ST, Alshbool FZ,
            Lau KH, Wergedal JE and Mohan S.
  TITLE     Claudin 18 is a novel negative regulator of bone resorption and
            osteoclast differentiation
  JOURNAL   J. Bone Miner. Res. 27 (7), 1553-1565 (2012)
   PUBMED   22437732
REFERENCE   2  (bases 1 to 1574)
  AUTHORS   Krause G, Winkler L, Mueller SL, Haseloff RF, Piontek J and Blasig
            IE.
  TITLE     Structure and function of claudins
  JOURNAL   Biochim. Biophys. Acta 1778 (3), 631-645 (2008)
   PUBMED   18036336
  REMARK    Review article
REFERENCE   3  (bases 1 to 1574)
  AUTHORS   Fernandez AL, Koval M, Fan X and Guidot DM.
  TITLE     Chronic alcohol ingestion alters claudin expression in the alveolar
            epithelium of rats
  JOURNAL   Alcohol 41 (5), 371-379 (2007)
   PUBMED   17889313
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC088427.1.
            On Apr 20, 2005 this sequence version replaced XM_236603.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC088427.1, CF110345.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16676785, SAMN16676786
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1574
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q31"
     gene            1..1574
                     /gene="Cldn18"
                     /note="claudin 18"
                     /db_xref="GeneID:315953"
                     /db_xref="RGD:1359696"
     CDS             33..818
                     /gene="Cldn18"
                     /note="claudin 18-like"
                     /codon_start=1
                     /product="claudin-18 precursor"
                     /protein_id="NP_001014118.1"
                     /db_xref="GeneID:315953"
                     /db_xref="RGD:1359696"
                     /translation="
MATTTCQVVGLLLSLLGLAGCIAATGMDMWSTQDLYDNPVTSVFQYEGLWRSCVQQSSGFTECRPYFTILGLPAMLQAVRALMIVGIVLGVIGILVSIFALKCIRIGSMDDSAKAKMTLTSGIMFIISGVCAIIGVSVFANMLVTNFWMSTANMYSGMGGMVQTVQTRYTFGAALFVGWIAGGLTLIGGVMMCIACRGLTPDDRNFKAVSYHASGQNVAYKPGGFKASTGFGSNARNKKIYDGGARTEDDEQSHPTKYDYV"
     sig_peptide     33..101
                     /gene="Cldn18"
                     /inference="COORDINATES: ab initio prediction:SignalP:4.0"
     misc_feature    <159..605
                     /gene="Cldn18"
                     /note="PMP-22/EMP/MP20/Claudin family; Region:
                     PMP22_Claudin; cl21598"
                     /db_xref="CDD:304458"
     STS             920..1112
                     /gene="Cldn18"
                     /standard_name="RH128616"
                     /db_xref="UniSTS:211924"
     STS             1249..1437
                     /gene="Cldn18"
                     /standard_name="RH132062"
                     /db_xref="UniSTS:215345"
ORIGIN      
ctcctggaagtctgtgcccagcagctgaagccatggccaccaccacgtgccaggtggtagggctcctcctgtccctcctgggtctggccggctgcatagccgccactggaatggacatgtggagcactcaggacctgtatgataacccagtcacctccgtgttccagtatgaagggctctggaggagttgcgtgcaacagagctcggggttcactgagtgccggccatacttcaccatcctgggccttccagccatgctgcaagcagtgcgagccctgatgatcgtgggcattgttctgggggtcatcggcatcctggtgtccatcttcgccctgaagtgcattcgcattggcagcatggatgactctgccaaggccaagatgactctgacttctgggattatgttcatcatctcaggagtctgtgcaatcattggtgtgtctgtgtttgccaacatgctggtaaccaacttctggatgtccacggccaacatgtacagcggcatgggtgggatggtgcagaccgttcagaccaggtacacttttggtgcagctctgtttgtgggctggatcgctggaggcctcacactaattggaggtgtgatgatgtgcattgcttgccgtggcctgactcctgatgaccgcaacttcaaagccgtgtcctaccacgcttctggccaaaatgttgcctataagcctggaggctttaaggccagcactggctttgggtccaacgccagaaacaagaagatatatgatgggggtgcccgcacagaagacgatgaacaatctcatcctaccaagtacgactatgtgtagtgctctaagaccgcccccccaacatgtgtgcagaagaaacccttccccaaggaaagctcaccccaaagcaaggagattctaccttgttcccttgttgcttttgactgacggttgaaagttggtaaagtcttaatttcatctgtggggaggctagacagtcttggccacacgtctctaaatactccatcacaaaacaaccgagttaccatttacaggttaagagaccaccacacccacccttcccaatcctctgtttttttaccatagtaaatctggtgatggaatgtaattcgactcatggactaatactttgataatttctagaaatttaagcctgatgatgatctatttcccagcttgaccccacccacccccccagggaaattttaaaagaaaaaaatagattaaaaggcattatttactactcaattttgccttaccaacctcactgataataatgaacaccgattagagaaagaatgctagaggaaagatggttgtggcctccccagtctgtcatctgaacccttcatacatggtgatctagaacattattagccacggtgatcttcaaggaggcaaacaagtcctgtctgcttctcttggcatctgctgactctaacaagaccgtttcagaactttccactggaagtcctcttcctctcagaagtcagaaattctccctagaagaataagaaataaattcttttggtaacctgaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa
//

by @meso_cacase at DBCLS
This page is licensed under a Creative Commons Attribution 4.0 International License (CC BY 4.0).

If you use GGRNA in your work, please cite:
Naito Y, Bono H. (2012)
GGRNA: an ultrafast, transcript-oriented search engine for genes and transcripts.
Nucleic Acids Res., 40, W592-W596. [Full Text]