LOCUS       NM_001009645            2098 bp    mRNA    linear   ROD 28-APR-2025
DEFINITION  Rattus norvegicus kinesin family member 22 (Kif22), mRNA.
ACCESSION   NM_001009645 XM_215074
VERSION     NM_001009645.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2098)
  AUTHORS   Iemura,K. and Tanaka,K.
  TITLE     Chromokinesin Kid and kinetochore kinesin CENP-E differentially
            support chromosome congression without end-on attachment to
            microtubules
  JOURNAL   Nat Commun 6, 6447 (2015)
   PUBMED   25743205
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2098)
  AUTHORS   Santamaria,A., Nagel,S., Sillje,H.H.W. and Nigg,E.A.
  TITLE     The spindle protein CHICA mediates localization of the
            chromokinesin Kid to the mitotic spindle
  JOURNAL   Curr Biol 18 (10), 723-729 (2008)
   PUBMED   18485706
REFERENCE   3  (bases 1 to 2098)
  AUTHORS   Zhu,C., Zhao,J., Bibikova,M., Leverson,J.D., Bossy-Wetzel,E.,
            Fan,J.B., Abraham,R.T. and Jiang,W.
  TITLE     Functional analysis of human microtubule-based motor proteins, the
            kinesins and dyneins, in mitosis/cytokinesis using RNA interference
  JOURNAL   Mol Biol Cell 16 (7), 3187-3199 (2005)
   PUBMED   15843429
REFERENCE   4  (bases 1 to 2098)
  AUTHORS   Dickins,R.A., Frew,I.J., House,C.M., O'Bryan,M.K., Holloway,A.J.,
            Haviv,I., Traficante,N., de Kretser,D.M. and Bowtell,D.D.
  TITLE     The ubiquitin ligase component Siah1a is required for completion of
            meiosis I in male mice
  JOURNAL   Mol Cell Biol 22 (7), 2294-2303 (2002)
   PUBMED   11884614
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC088421.1.
            
            On Jan 13, 2005 this sequence version replaced XM_215074.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC088421.1, SRR8487231.29610.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2098
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q37"
     gene            1..2098
                     /gene="Kif22"
                     /note="kinesin family member 22"
                     /db_xref="GeneID:293502"
                     /db_xref="RGD:1311886"
     exon            1..78
                     /gene="Kif22"
                     /inference="alignment:Splign:2.1.0"
     CDS             21..1994
                     /gene="Kif22"
                     /note="kinesin-like protein KIF22-like"
                     /codon_start=1
                     /product="kinesin-like protein KIF22"
                     /protein_id="NP_001009645.1"
                     /db_xref="GeneID:293502"
                     /db_xref="RGD:1311886"
                     /translation="

MNVRAKKKPQQREMASASSGPSRSLSKGGVSRRPPLARVRVAVRLRPFMDEAKEPPCVRGIDSCSLEVANWRKYQETLKYQFDAFYGEKSTQQDVYVGSVQPILRHLLEGQNASVLAYGPTGAGKTHTMLGSPEQPGVIPRALMDLLQLTREESAEGRPWDISVAMSYLEIYQEKVLDLLDPASGDLVIREDCRGNILIPGLTQKPITSFSEFEQHFLPASRNRVVGATRLNQRSSRSHAVLLVKVEQRERLTPFRQREGKLYLIDLAGSEDNRRTGNQGIRLKESGAINTSLFVLGKVVDALNQGLPRIPYRDSKLTRLLQDSLGGSAHSILIANIAPERRFYQDTISALNFTARSKEVINRPFTNESLQPHALAPVKLPQKELLGPSEAKKAKGPEEESTGSPESTAAPASASQKLSLLQKLSNMDPAMLENLLSMERLLGSQGSQGIPLLNTPKRERMVLIKTVEEKNLEIERLKMKQKELEAKVLAQEALDPKEKENTPTILQPSSSCSGSVAKPLKKAVVMPLQRIQKQSESSNKIHLLKKGHKRKLESSHESEAVEKDEDYWEIQISPELLARGRKKLLHLLNEGSARDLRSLQRIGQKKAQLIVGWRELHGPFNEVEDLEQVEGISGKQVESFLKANLLSLAASQHSGPS"

     misc_feature    21..119
                     /gene="Kif22"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5I0E8.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    132..1094
                     /gene="Kif22"
                     /note="Kinesin motor domain, KIF22/Kid-like subgroup;
                     Region: KISc_KID_like; cd01376"
                     /db_xref="CDD:276827"
     misc_feature    order(156..158,375..377,384..386,390..401,816..818)
                     /gene="Kif22"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:276827"
     misc_feature    order(957..959,966..968,975..977)
                     /gene="Kif22"
                     /note="microtubule interaction site [polypeptide binding];
                     other site"
                     /db_xref="CDD:276827"
     misc_feature    1182..1265
                     /gene="Kif22"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5I0E8.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    1230..1232
                     /gene="Kif22"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q14807; propagated from
                     UniProtKB/Swiss-Prot (Q5I0E8.1); phosphorylation site"
     misc_feature    1275..1277
                     /gene="Kif22"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q14807; propagated from
                     UniProtKB/Swiss-Prot (Q5I0E8.1); phosphorylation site"
     misc_feature    1350..1352
                     /gene="Kif22"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q14807; propagated from
                     UniProtKB/Swiss-Prot (Q5I0E8.1); phosphorylation site"
     misc_feature    1629..1631
                     /gene="Kif22"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q14807; propagated from
                     UniProtKB/Swiss-Prot (Q5I0E8.1); phosphorylation site"
     misc_feature    1680..1682
                     /gene="Kif22"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q14807; propagated from
                     UniProtKB/Swiss-Prot (Q5I0E8.1); phosphorylation site"
     misc_feature    1737..1739
                     /gene="Kif22"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q14807; propagated from
                     UniProtKB/Swiss-Prot (Q5I0E8.1); phosphorylation site"
     misc_feature    1782..1934
                     /gene="Kif22"
                     /note="DNA uptake protein ComE or related DNA-binding
                     protein [Replication, recombination and repair]; Region:
                     ComEA; COG1555"
                     /db_xref="CDD:441164"
     exon            79..262
                     /gene="Kif22"
                     /inference="alignment:Splign:2.1.0"
     exon            263..390
                     /gene="Kif22"
                     /inference="alignment:Splign:2.1.0"
     exon            391..545
                     /gene="Kif22"
                     /inference="alignment:Splign:2.1.0"
     exon            546..755
                     /gene="Kif22"
                     /inference="alignment:Splign:2.1.0"
     exon            756..986
                     /gene="Kif22"
                     /inference="alignment:Splign:2.1.0"
     exon            987..1140
                     /gene="Kif22"
                     /inference="alignment:Splign:2.1.0"
     exon            1141..1276
                     /gene="Kif22"
                     /inference="alignment:Splign:2.1.0"
     exon            1277..1445
                     /gene="Kif22"
                     /inference="alignment:Splign:2.1.0"
     exon            1446..1611
                     /gene="Kif22"
                     /inference="alignment:Splign:2.1.0"
     exon            1612..1673
                     /gene="Kif22"
                     /inference="alignment:Splign:2.1.0"
     exon            1674..1886
                     /gene="Kif22"
                     /inference="alignment:Splign:2.1.0"
     exon            1887..1946
                     /gene="Kif22"
                     /inference="alignment:Splign:2.1.0"
     exon            1947..2073
                     /gene="Kif22"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

ggtccgaagaagggagggatatgaacgttagggctaagaaaaagccgcagcaacgggagatggcgtcggccagctcaggacccagtcgctctctaagcaagggaggagtcagcagacgtcctcctctagctcgagtaagggtggccgtgcgactgcgcccatttatggatgaagcaaaggaaccaccctgtgtgcgaggcatagacagctgctctcttgaagtagccaactggaggaaataccaggagactctaaaatatcagtttgatgctttctatggagagaagagcactcagcaagatgtctatgtgggttcagtacagcccattctcaggcacttgctggaagggcagaatgccagtgtacttgcctatgggcctactggggcagggaagacacacacaatgctgggtagcccagaacagcctggagtgattcctcgggctctcatggacctcctgcaactaacaagggaagagagtgctgagggccggccctgggacatttctgttgctatgtcctatttggagatctaccaggaaaaggtattagacctcttggatcctgcatcaggagacctagtgatccgagaggactgtcgagggaacatcctgattccaggcctcactcagaagcccatcactagcttctctgagttcgagcagcacttccttccagccagtagaaatcgagtcgtaggagctacccggcttaaccagcgctcttcccgcagtcatgcggtgctcttggtcaaggtagaacagcgtgaacgtttgactccatttcgccagcgggaaggaaaactctaccttattgatttggctggttcagaggacaaccgtcgcacaggcaaccagggaattcggctaaaagagagtggagccatcaacacctccctctttgtattgggcaaagtggtggatgcattaaaccagggcctccctcgtataccataccgggacagcaagctcactcgtctgctgcaggactctctgggaggttcagctcatagcatcctcattgccaacatcgctcctgaaaggcgtttttaccaggatacgatctcagcattgaacttcactgcgaggtccaaggaggtgattaaccggcctttcaccaatgagagcctacagcctcatgccttggcacctgttaagctgcctcagaaagaactgctaggcccatcagaggcaaagaaagccaaaggccctgaagaagaatcaactgggagccctgagtctacagcagctccagcatctgcctcccagaaattaagcctcttacagaagctaagcaatatggatccagccatgttggagaacctcctgagtatggaacgtttgctgggttcccaggggagccaagggatacctctactgaataccccaaagcgagagcgaatggtactcattaagacagtggaggaaaagaacttagagattgagaggcttaagatgaagcaaaaagaactggaagccaaggtgctggcccaggaggcactggatccaaaggaaaaagagaacactcccacaattctccagccctcttcctcctgtagtggctcagtggctaagcccctgaaaaaggctgtggtgatgcccctgcaacggattcagaagcagtcagagtcctcaaacaagatccacctcctgaagaaaggccacaaaaggaagctggagtcatcacatgagtcagaagctgtggaaaaggatgaggactactgggagatacaaattagcccagagttactggcacgggggcgcaaaaaattattgcatctgctgaatgaaggctcagctcgggatctgcgaagcctgcagcgaattggccagaagaaggcccagctcattgtgggctggagggagctgcatggcccctttaatgaggtggaggacctggaacaggtggaaggcatctctgggaagcaggtagagtctttcctgaaggcgaatctcttgagcttggctgccagccagcacagtggtccctcttgactaccagctcttgacactacctttttcttttaaaaattcttgtatagtgatgttgtgtaaatacagcttttattccgtgaaaaaaaaaaaaaaaaaaaaaaaaa

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