LOCUS       NM_001009645            2098 bp    mRNA    linear   ROD 20-JUN-2021
DEFINITION  Rattus norvegicus kinesin family member 22 (Kif22), mRNA.
ACCESSION   NM_001009645 XM_215074
VERSION     NM_001009645.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2098)
  AUTHORS   Iemura K and Tanaka K.
  TITLE     Chromokinesin Kid and kinetochore kinesin CENP-E differentially
            support chromosome congression without end-on attachment to
            microtubules
  JOURNAL   Nat Commun 6, 6447 (2015)
   PUBMED   25743205
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2098)
  AUTHORS   Santamaria A, Nagel S, Sillje HHW and Nigg EA.
  TITLE     The spindle protein CHICA mediates localization of the
            chromokinesin Kid to the mitotic spindle
  JOURNAL   Curr Biol 18 (10), 723-729 (2008)
   PUBMED   18485706
REFERENCE   3  (bases 1 to 2098)
  AUTHORS   Zhu C, Zhao J, Bibikova M, Leverson JD, Bossy-Wetzel E, Fan JB,
            Abraham RT and Jiang W.
  TITLE     Functional analysis of human microtubule-based motor proteins, the
            kinesins and dyneins, in mitosis/cytokinesis using RNA interference
  JOURNAL   Mol Biol Cell 16 (7), 3187-3199 (2005)
   PUBMED   15843429
REFERENCE   4  (bases 1 to 2098)
  AUTHORS   Dickins RA, Frew IJ, House CM, O'Bryan MK, Holloway AJ, Haviv I,
            Traficante N, de Kretser DM and Bowtell DD.
  TITLE     The ubiquitin ligase component Siah1a is required for completion of
            meiosis I in male mice
  JOURNAL   Mol Cell Biol 22 (7), 2294-2303 (2002)
   PUBMED   11884614
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC088421.1.
            On Jan 13, 2005 this sequence version replaced XM_215074.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC088421.1 [ECO:0000332]
            RNAseq introns              :: mixed/partial sample support
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2098
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q37"
     gene            1..2098
                     /gene="Kif22"
                     /note="kinesin family member 22"
                     /db_xref="GeneID:293502"
                     /db_xref="RGD:1311886"
     exon            1..78
                     /gene="Kif22"
                     /inference="alignment:Splign:2.1.0"
     CDS             21..1994
                     /gene="Kif22"
                     /note="kinesin-like protein KIF22-like"
                     /codon_start=1
                     /product="kinesin-like protein KIF22"
                     /protein_id="NP_001009645.1"
                     /db_xref="GeneID:293502"
                     /db_xref="RGD:1311886"
                     /translation="

MNVRAKKKPQQREMASASSGPSRSLSKGGVSRRPPLARVRVAVRLRPFMDEAKEPPCVRGIDSCSLEVANWRKYQETLKYQFDAFYGEKSTQQDVYVGSVQPILRHLLEGQNASVLAYGPTGAGKTHTMLGSPEQPGVIPRALMDLLQLTREESAEGRPWDISVAMSYLEIYQEKVLDLLDPASGDLVIREDCRGNILIPGLTQKPITSFSEFEQHFLPASRNRVVGATRLNQRSSRSHAVLLVKVEQRERLTPFRQREGKLYLIDLAGSEDNRRTGNQGIRLKESGAINTSLFVLGKVVDALNQGLPRIPYRDSKLTRLLQDSLGGSAHSILIANIAPERRFYQDTISALNFTARSKEVINRPFTNESLQPHALAPVKLPQKELLGPSEAKKAKGPEEESTGSPESTAAPASASQKLSLLQKLSNMDPAMLENLLSMERLLGSQGSQGIPLLNTPKRERMVLIKTVEEKNLEIERLKMKQKELEAKVLAQEALDPKEKENTPTILQPSSSCSGSVAKPLKKAVVMPLQRIQKQSESSNKIHLLKKGHKRKLESSHESEAVEKDEDYWEIQISPELLARGRKKLLHLLNEGSARDLRSLQRIGQKKAQLIVGWRELHGPFNEVEDLEQVEGISGKQVESFLKANLLSLAASQHSGPS"

     misc_feature    21..119
                     /gene="Kif22"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5I0E8.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    132..1121
                     /gene="Kif22"
                     /note="Kinesin motor, catalytic domain. ATPase; Region:
                     KISc; smart00129"
                     /db_xref="CDD:214526"
     misc_feature    132..1094
                     /gene="Kif22"
                     /note="Kinesin motor domain, KIF22/Kid-like subgroup;
                     Region: KISc_KID_like; cd01376"
                     /db_xref="CDD:276827"
     misc_feature    order(156..158,375..377,384..386,390..401,816..818)
                     /gene="Kif22"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:276827"
     misc_feature    order(957..959,966..968,975..977)
                     /gene="Kif22"
                     /note="microtubule interaction site [polypeptide binding];
                     other site"
                     /db_xref="CDD:276827"
     misc_feature    1182..1265
                     /gene="Kif22"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5I0E8.1);
                     Region: Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite"
     misc_feature    1230..1232
                     /gene="Kif22"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q14807; propagated from
                     UniProtKB/Swiss-Prot (Q5I0E8.1); phosphorylation site"
     misc_feature    1275..1277
                     /gene="Kif22"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q14807; propagated from
                     UniProtKB/Swiss-Prot (Q5I0E8.1); phosphorylation site"
     misc_feature    1350..1352
                     /gene="Kif22"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q14807; propagated from
                     UniProtKB/Swiss-Prot (Q5I0E8.1); phosphorylation site"
     misc_feature    1629..1631
                     /gene="Kif22"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q14807; propagated from
                     UniProtKB/Swiss-Prot (Q5I0E8.1); phosphorylation site"
     misc_feature    1680..1682
                     /gene="Kif22"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q14807; propagated from
                     UniProtKB/Swiss-Prot (Q5I0E8.1); phosphorylation site"
     misc_feature    1737..1739
                     /gene="Kif22"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q14807; propagated from
                     UniProtKB/Swiss-Prot (Q5I0E8.1); phosphorylation site"
     misc_feature    1782..1934
                     /gene="Kif22"
                     /note="Helix-hairpin-helix motif; Region: HHH_3;
                     pfam12836"
                     /db_xref="CDD:289597"
     exon            79..262
                     /gene="Kif22"
                     /inference="alignment:Splign:2.1.0"
     exon            263..390
                     /gene="Kif22"
                     /inference="alignment:Splign:2.1.0"
     exon            391..545
                     /gene="Kif22"
                     /inference="alignment:Splign:2.1.0"
     exon            546..755
                     /gene="Kif22"
                     /inference="alignment:Splign:2.1.0"
     exon            756..986
                     /gene="Kif22"
                     /inference="alignment:Splign:2.1.0"
     exon            987..1140
                     /gene="Kif22"
                     /inference="alignment:Splign:2.1.0"
     exon            1141..1276
                     /gene="Kif22"
                     /inference="alignment:Splign:2.1.0"
     exon            1277..1445
                     /gene="Kif22"
                     /inference="alignment:Splign:2.1.0"
     exon            1446..1611
                     /gene="Kif22"
                     /inference="alignment:Splign:2.1.0"
     exon            1612..1673
                     /gene="Kif22"
                     /inference="alignment:Splign:2.1.0"
     exon            1674..1886
                     /gene="Kif22"
                     /inference="alignment:Splign:2.1.0"
     exon            1887..1946
                     /gene="Kif22"
                     /inference="alignment:Splign:2.1.0"
     exon            1947..2073
                     /gene="Kif22"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

ggtccgaagaagggagggatatgaacgttagggctaagaaaaagccgcagcaacgggagatggcgtcggccagctcaggacccagtcgctctctaagcaagggaggagtcagcagacgtcctcctctagctcgagtaagggtggccgtgcgactgcgcccatttatggatgaagcaaaggaaccaccctgtgtgcgaggcatagacagctgctctcttgaagtagccaactggaggaaataccaggagactctaaaatatcagtttgatgctttctatggagagaagagcactcagcaagatgtctatgtgggttcagtacagcccattctcaggcacttgctggaagggcagaatgccagtgtacttgcctatgggcctactggggcagggaagacacacacaatgctgggtagcccagaacagcctggagtgattcctcgggctctcatggacctcctgcaactaacaagggaagagagtgctgagggccggccctgggacatttctgttgctatgtcctatttggagatctaccaggaaaaggtattagacctcttggatcctgcatcaggagacctagtgatccgagaggactgtcgagggaacatcctgattccaggcctcactcagaagcccatcactagcttctctgagttcgagcagcacttccttccagccagtagaaatcgagtcgtaggagctacccggcttaaccagcgctcttcccgcagtcatgcggtgctcttggtcaaggtagaacagcgtgaacgtttgactccatttcgccagcgggaaggaaaactctaccttattgatttggctggttcagaggacaaccgtcgcacaggcaaccagggaattcggctaaaagagagtggagccatcaacacctccctctttgtattgggcaaagtggtggatgcattaaaccagggcctccctcgtataccataccgggacagcaagctcactcgtctgctgcaggactctctgggaggttcagctcatagcatcctcattgccaacatcgctcctgaaaggcgtttttaccaggatacgatctcagcattgaacttcactgcgaggtccaaggaggtgattaaccggcctttcaccaatgagagcctacagcctcatgccttggcacctgttaagctgcctcagaaagaactgctaggcccatcagaggcaaagaaagccaaaggccctgaagaagaatcaactgggagccctgagtctacagcagctccagcatctgcctcccagaaattaagcctcttacagaagctaagcaatatggatccagccatgttggagaacctcctgagtatggaacgtttgctgggttcccaggggagccaagggatacctctactgaataccccaaagcgagagcgaatggtactcattaagacagtggaggaaaagaacttagagattgagaggcttaagatgaagcaaaaagaactggaagccaaggtgctggcccaggaggcactggatccaaaggaaaaagagaacactcccacaattctccagccctcttcctcctgtagtggctcagtggctaagcccctgaaaaaggctgtggtgatgcccctgcaacggattcagaagcagtcagagtcctcaaacaagatccacctcctgaagaaaggccacaaaaggaagctggagtcatcacatgagtcagaagctgtggaaaaggatgaggactactgggagatacaaattagcccagagttactggcacgggggcgcaaaaaattattgcatctgctgaatgaaggctcagctcgggatctgcgaagcctgcagcgaattggccagaagaaggcccagctcattgtgggctggagggagctgcatggcccctttaatgaggtggaggacctggaacaggtggaaggcatctctgggaagcaggtagagtctttcctgaaggcgaatctcttgagcttggctgccagccagcacagtggtccctcttgactaccagctcttgacactacctttttcttttaaaaattcttgtatagtgatgttgtgtaaatacagcttttattccgtgaaaaaaaaaaaaaaaaaaaaaaaaa

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