LOCUS       XM_053224903            2761 bp    mRNA    linear   MAM 04-APR-2023
DEFINITION  PREDICTED: Acinonyx jubatus dicer 1, ribonuclease III (DICER1),
            transcript variant X9, mRNA.
ACCESSION   XM_053224903
VERSION     XM_053224903.1
DBLINK      BioProject: PRJNA923316
KEYWORDS    RefSeq.
SOURCE      Acinonyx jubatus (cheetah)
  ORGANISM  Acinonyx jubatus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;
            Acinonychinae; Acinonyx.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_069386) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_027475565.1-RS_2023_04
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 04/03/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2761
                     /organism="Acinonyx jubatus"
                     /mol_type="mRNA"
                     /isolate="Ajub_Pintada_27869175"
                     /db_xref="taxon:32536"
                     /chromosome="B3"
                     /sex="female"
                     /tissue_type="blood"
                     /dev_stage="adult"
                     /collected_by="Rui Bernardino"
     gene            1..2761
                     /gene="DICER1"
                     /note="dicer 1, ribonuclease III; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1
                     Protein"
                     /db_xref="GeneID:106977463"
     CDS             327..2618
                     /gene="DICER1"
                     /codon_start=1
                     /product="endoribonuclease Dicer isoform X7"
                     /protein_id="XP_053080878.1"
                     /db_xref="GeneID:106977463"
                     /translation="

MNESPALQPLSMAGLQLVTPASSPMGPFFGLPWQQEAIHDNIYTPRKYQVELLEAALDHNTIVCLNTGSGKTFIAVLLTKELSYQIRGDFNRSGKRTVFLVNSANQVAPQVSAVRTHSDLKVGEYSSLEVNAAWTKEKWNQEFTKHQVLVMTCYVALNVLKNGYLSLSDINLLVFDECHLAILDHPYREIMKLCENCPSCPRILGLTASILNGKCDPEELEEKIQKLEKILKSNAETATDLVVLDRYTSQPCEIVVDCGPFTDRSGLYGRLLLELEEALNFINDCNISVRSKERDSTSISKQILSDCRAVLVVLGPWCADKVAGMMVRELQKYIKHEQEELHRKFLLFTDTFLRKIHALCEEHFSPASLDLKFVTPKVIKLLEILRKYKPYERQQFESVEWYNNRNQDNYVSWSDSEDDDEDEEIEEKEKPETNFPSPFTNILCGIIFVERRYTAVVLNRLIKEAGKQDPELAYISSNFITGHGIGKNQPRNKQMEAEFRKQEEVLRKFRAHETNLLIATSIVEEGVDIPKCNLVVRFDLPTEYRSYVQSKGRARAPISNYIMLADTDKIKSFEEDLKTYKAIEKILRNKCSKSVDAGETDVDPVVDDDDVFPPYVLRPDDGGPRVTINTAIGHINRYCARLPSDPFTHLAPKCRTRELPDGTFYSTLYLPINSPLRASIVGPPMSCIRLAERVVALICCEKLHKIGELDDHLMPVGKETVKYEEELDLHDEEETSVPGRPGSTKRRQCYPKAVSIDSGMFEG"

     misc_feature    453..1046
                     /gene="DICER1"
                     /note="DEXH-box helicase domain of endoribonuclease Dicer;
                     Region: DEXHc_dicer; cd18034"
                     /db_xref="CDD:350792"
     misc_feature    order(453..464,471..473,522..545,666..668,855..857,
                     948..950)
                     /gene="DICER1"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:350792"
     misc_feature    order(630..635,702..707,780..782,786..791,798..800,
                     873..881)
                     /gene="DICER1"
                     /note="nucleic acid binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:350792"
     misc_feature    1164..1424
                     /gene="DICER1"
                     /note="Partner-binding domain of the endoribonuclease
                     Dicer; Region: Dicer_PBD; cd15903"
                     /db_xref="CDD:277191"
     misc_feature    order(1167..1169,1173..1178,1353..1358,1365..1370,
                     1377..1379,1386..1391,1398..1400)
                     /gene="DICER1"
                     /note="Trbp binding interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:277191"
     misc_feature    1443..2021
                     /gene="DICER1"
                     /note="C-terminal helicase domain of the endoribonuclease
                     Dicer; Region: SF2_C_dicer; cd18802"
                     /db_xref="CDD:350189"
     misc_feature    order(1674..1682,1890..1892,1947..1949,1953..1955)
                     /gene="DICER1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:350189"
     misc_feature    order(1902..1904,1908..1910,1983..1985,1989..1991)
                     /gene="DICER1"
                     /note="ATP binding site [chemical binding]; other site"
                     /db_xref="CDD:350189"
     misc_feature    2217..2483
                     /gene="DICER1"
                     /note="Dicer dimerization domain; Region: Dicer_dimer;
                     pfam03368"
                     /db_xref="CDD:427264"
ORIGIN      

acggcgagcgggaggaaatggcggcggcggcgccaggcggcaccgggaggcctgggctgtgacgcgcgcgccggagcggggtccgatggttctcgaaggcccgcggcgccccgtgctgcaggttacctagggtgtgaattaatacagacttggaaactgaaagaacttagaatcagcattttgagagcagaagcttgggcatgctgtgattttccaataaactgctatcacaatgtcaaaatgcagctcggacaacagcagcacagagatctcaaacattaaaacgtaagctgcgctagagcaaaatgcagtgagagaagcactggatgaatgaaagccctgctttgcagcccctcagcatggcgggcctgcagctcgtgacccctgcctcctcaccaatgggccctttctttggactgccatggcaacaagaagcaatccatgataacatttatacgccaagaaaataccaggtggaactgctcgaagcagctctggatcataacaccatagtctgtttaaacactggctcagggaagacgtttattgccgtactactcactaaagagctgtcctatcagatcaggggagacttcaacagaagcggaaaaaggacggtgttcttggtcaactctgcaaaccaggttgctccacaagtgtcagctgtcagaactcattcagatctcaaggttggggaatactcaagcctggaagtaaatgcagcttggacaaaagagaaatggaaccaagagtttactaagcaccaggttcttgttatgacctgctatgtcgccttgaatgttttgaaaaatggttacttatcgctgtcggacattaaccttttggtgtttgatgagtgtcatcttgcgatcctagaccacccctaccgagaaattatgaagctctgtgaaaactgtccatcgtgtcctcgtatcttgggactgactgcttccattttaaatgggaaatgcgaccccgaggaattggaagaaaagattcagaagctggagaaaatcctcaagagtaatgctgagaccgcaactgacctggtggtcttggacagatacacttctcaaccgtgtgagattgtggtggactgtgggccgttcacggaccgaagtggcctctatggcaggctgctgctggagctggaggaggcgctgaactttatcaacgactgtaacatatctgtgcgttcgaaagagagagattcgacttcaatttctaagcagatactgtcagactgtcgtgccgtgttggtggtcctgggcccctggtgtgcagataaggtcgctgggatgatggtccgggagctgcagaagtacatcaaacacgagcaagaggagctgcacaggaaattcctattgtttacagacaccttcctaaggaaaatccatgcactatgtgaagagcacttctctcctgcctcacttgacctgaaatttgtaactcctaaagtaataaaactgctcgaaatcttgcgcaagtacaaaccgtatgagcggcagcagttcgagagcgtcgagtggtataataacaggaatcaggataattacgtgtcctggagtgattctgaggatgatgacgaggacgaagagatcgaagaaaaagagaagccggagaccaacttcccgtctccgttcaccaacatcttatgcgggatcatttttgtggaaagaagatacacagcagttgtcttaaacagattgataaaggaagctggcaaacaagatccagagctggcttacatcagcagcaattttataactggacatggcattggaaagaatcagcctcgtaacaaacagatggaagcagaattcagaaaacaggaagaggtacttaggaaatttcgagcacatgagaccaacctgcttattgcgacaagcattgtggaagagggtgttgacataccaaaatgcaacttggtggttcgttttgatttacccacagagtatcgatcctatgttcaatctaagggacgagcaagggcaccgatctctaattacataatgttagcagatacagacaaaataaaaagttttgaagaagaccttaaaacatacaaagctattgaaaagatcttgagaaacaagtgttccaagtccgttgatgcgggtgagactgacgttgatcctgtcgtggatgatgacgatgtgttcccgccatatgtgttgaggcccgatgacggtggtccgcgagtcacgatcaacacggccattggacacatcaacagatactgtgctagattaccaagtgatccgtttactcatctagctcctaaatgtagaactcgagagttgcctgatggtacattttattcaactctttatctgccaattaactcacctcttcgagcctccattgttggtccgccaatgagctgtatacgattggccgaaagagttgtagctctcatttgctgtgaaaaactgcacaaaattggtgaactggatgaccatttgatgccagttgggaaagagacggttaaatatgaagaagagctcgatttacatgacgaagaagagaccagcgttccaggaagaccaggttccacaaagcgaagacagtgctacccaaaggcagttagtatcgattccggaatgtttgagggatagctatcccaaacccgatcagccctgttacctgtatgtgataggaatggttctgacgacacccttacctgatgaactcaacttcagaaggcggaagctctatccccctgaggataccaccagatgctttggaatactgacggcca

//