LOCUS       XM_026513068            1558 bp    mRNA    linear   MAM 12-JUN-2023
DEFINITION  PREDICTED: Ursus arctos homeobox B8 (HOXB8), transcript variant X2,
            mRNA.
ACCESSION   XM_026513068
VERSION     XM_026513068.4
DBLINK      BioProject: PRJNA832286
KEYWORDS    RefSeq.
SOURCE      Ursus arctos (brown bear)
  ORGANISM  Ursus arctos
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae;
            Ursus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NW_026622919) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Jun 12, 2023 this sequence version replaced XM_026513068.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_023065955.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Gnomon; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1558
                     /organism="Ursus arctos"
                     /mol_type="mRNA"
                     /isolate="Adak"
                     /db_xref="taxon:9644"
                     /chromosome="Unknown"
                     /sex="male"
                     /tissue_type="blood"
                     /dev_stage="adult"
                     /ecotype="North America"
     gene            1..1558
                     /gene="HOXB8"
                     /note="homeobox B8; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 11 Proteins"
                     /db_xref="GeneID:113265579"
     CDS             1..729
                     /gene="HOXB8"
                     /codon_start=1
                     /product="homeobox protein Hox-B8 isoform X2"
                     /protein_id="XP_026368853.1"
                     /db_xref="GeneID:113265579"
                     /translation="

MSSYFVNSLFSKYKTGESLRPNYYDCGFAQDLGGRPTVVYGPSSGGSFQHPSQIQEFYHGPSSLSTAPYQQNPCAVACHGDPGNFYGYDPLQRQSLFGAQDPDLVQYADCKLAAASGLGEEAEGSEQSPSPTQLFPWMRPQAAGRRRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKFPSSKCEQEELEKQKLERAPEAADEGDAQKGDKK"

     misc_feature    order(436..450,454..456,505..507,523..525,562..564,
                     568..573,580..585,589..597,601..606)
                     /gene="HOXB8"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:238039"
     misc_feature    order(442..444,451..453,571..573,580..585,592..594)
                     /gene="HOXB8"
                     /note="specific DNA base contacts [nucleotide binding];
                     other site"
                     /db_xref="CDD:238039"
     misc_feature    445..603
                     /gene="HOXB8"
                     /note="Homeobox domain; Region: Homeobox; pfam00046"
                     /db_xref="CDD:425441"
ORIGIN      

atgagctcttatttcgtcaactcactgttctccaaatacaaaaccggggagtccctgcgccccaattattatgactgcggcttcgcccaggacctgggcggccgacccaccgtggtgtacggtcccagcagcggcggcagcttccagcacccgtcgcaaatccaggagttctaccacgggccgtcgtcgctgtccaccgctccctaccagcagaacccgtgcgccgtggcgtgccacggggacccgggcaacttctacggctacgacccgttgcagcggcagagcctgttcggtgcgcaggatccagacctggtgcagtacgccgactgcaagctcgccgccgccagcggcctgggcgaggaggccgagggttcagagcagagtccgtcgcccacacagctcttcccctggatgcgcccgcaagccgccggacgcaggcgaggccgacagacctacagccgctaccagaccctggagctggagaaggagttcctatttaatccctatctgactcgcaagcggcggatcgaggtatcgcatgcgctgggactgacagagagacaggtcaaaatctggttccagaaccggaggatgaagtggaaaaaagagaacaacaaagacaagttccccagtagcaaatgcgagcaggaggagctggagaaacagaagctggagcgggccccggaggcggcggacgagggcgacgcgcagaagggcgacaagaagtaggctccagctgggactgccagggccgcggccgccctccgtccgtgggtcccccgaccacgccaccgccgtcgcccgcccccgcccgagagagctctggccccgcgagcggggcccggagcccggcctcccgctgcagcgtcccccgccgcgccagtccccgctagtggtagtatctcgtaatagcttctgtgtgtgagctgccgtggatctccttcccttctcttgggggccgggggggaaagaaaaggattttaagcaaggactccctcgccctgcgagggtgagcggctgcggcctggctgagccccccacgcccccgccccatgtaaaaagcctccttgtgcaatggtcttttttcctttgaacgtgcttctttgtaatgaccgaggtaccgatttctgctaagttctcccaacaacatgaaactgcctattcacgccgtaattctttctgtctccctctcctctctctctctctcttctctctctctctctctccgtcctcatttctccctcccaacccctctctccccgctgccctccctagctcgctggctttctctcttgcttctctcttttcctcccccccctttggtttggcaatttcgtcttaagtgtttctcaaaagaggttactttagttagcatgcgcgctgtgggcaattgttaaaagtgttcttaggtttactgtgaagagaatgtatcctgtatccgtgaattgctttattggggggtgggagggctaattatatattttgttgttcctctatactttgttctgttgtctgcgcctgaaaagggcggaagagttacaataaagtttacaagcga

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