LOCUS       NM_175136               5411 bp    mRNA    linear   ROD 31-OCT-2023
DEFINITION  Mus musculus ring finger protein 122 (Rnf122), transcript variant
            4, mRNA.
ACCESSION   NM_175136
VERSION     NM_175136.3
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5411)
  AUTHORS   Bedogni F and Hevner RF.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5411)
  AUTHORS   Wang W, Jiang M, Liu S, Zhang S, Liu W, Ma Y, Zhang L, Zhang J and
            Cao X.
  TITLE     RNF122 suppresses antiviral type I interferon production by
            targeting RIG-I CARDs to mediate RIG-I degradation
  JOURNAL   Proc Natl Acad Sci U S A 113 (34), 9581-9586 (2016)
   PUBMED   27506794
  REMARK    GeneRIF: RNF122 suppresses antiviral type I interferon production
            by targeting RIG-I caspase activation and recruitment domains to
            mediate RIG-I degradation.
REFERENCE   3  (bases 1 to 5411)
  AUTHORS   Piao Y, Ko NT, Lim MK and Ko MS.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC109163.16.
            
            On Feb 8, 2019 this sequence version replaced NM_175136.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC038399.1, AK085376.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-346               AC109163.16        96302-96647
            347-503             AC109163.16        102906-103062
            504-549             AC109163.16        109327-109372
            550-591             AC109163.16        109641-109682
            592-671             AC109163.16        112730-112809
            672-5411            AC109163.16        113054-117793
FEATURES             Location/Qualifiers
     source          1..5411
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 17.97 cM"
     gene            1..5411
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
                     /note="ring finger protein 122"
                     /db_xref="GeneID:68867"
                     /db_xref="MGI:MGI:1916117"
     exon            1..346
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
                     /inference="alignment:Splign:2.1.0"
     misc_feature    202..204
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
                     /note="upstream in-frame stop codon"
     CDS             322..786
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
                     /note="isoform 4 is encoded by transcript variant 4; ring
                     finger protein 122 homolog"
                     /codon_start=1
                     /product="RING finger protein 122 isoform 4"
                     /protein_id="NP_780345.1"
                     /db_xref="CCDS:CCDS22220.1"
                     /db_xref="GeneID:68867"
                     /db_xref="MGI:MGI:1916117"
                     /translation="

MHPFQWCNGCFCGLGLVSTNKSCSMPPISFQDLPLNIYMVIFGTGIFVFMLSLIFCCYFISKLRNQAQSERYGYKEVVLKGDAKKLQLYGTCAVCLEDFKGKDELGVLPCQHAFHRKCLVKWLEVRCVCPMCNKPIAGPTETSQSIGILLDELV"

     misc_feature    439..501
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8BP31.1);
                     transmembrane region"
     misc_feature    592..729
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
                     /note="RING finger, H2 subclass, found in RING finger
                     protein 122 (RNF122) and similar proteins; Region:
                     RING-H2_RNF122; cd16676"
                     /db_xref="CDD:438338"
     misc_feature    order(595..597,604..606,649..651,655..657,664..666,
                     673..675,706..708,715..717)
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
                     /note="Zn binding site [ion binding]; other site"
                     /db_xref="CDD:438338"
     exon            347..503
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            504..549
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            550..591
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            592..671
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            672..5411
                     /gene="Rnf122"
                     /gene_synonym="1110063C11Rik"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      

gtcagttttcggaatcccagcgcgcactgctcagcgcagtgggacccaagcccggcttcgtgtcctggctactgccttctcggccgggcatcccggctctctcggctgccctcccggcccgggccctcggtagggcttcgctccgaaaagactttgcttcctcctctgccctctttgttgctctgcaaaccggcctctctgtaacccttgactccactcctccgggagttgcatctccatcccggcggtctcagtgcacagcccctccagctccaacaccttgcctcggtttgctcccggaagccgaccttgacttcattgatgcacccattccagtggtgtaacgggtgtttctgtggcctgggactggttagtaccaacaagtcctgctcaatgccaccgatcagtttccaagaccttcccctcaatatctacatggtcatcttcggcacaggcatcttcgtcttcatgcttagcctcatcttctgctgctacttcatcagcaaactccggaaccaggctcagagcgagcgatacggctacaaggaggtggtgcttaaaggtgatgctaagaagttacagctctatgggacctgtgcagtttgcctggaagacttcaaggggaaggatgaactaggcgtgcttccatgccagcatgcctttcaccgcaagtgtctggtgaagtggctagaagtacgttgtgtctgccccatgtgcaacaagcccatcgcgggccccacggagacctcgcagagcatcgggatcctgctggatgaactggtgtaagcgctcctggcacatggaccctgggaaagactgccgactttgggtacctgggtttctctacacaatgaacaagactcacacacacctaaaggcaaggatgacagagccgagcttctcccagcaccgcaggaccagtaccagacttgtccagtctccgcctcccagggcttctctccgttatccatttccaatggcctcatccaggtagactgctctatcctggcactggactgaccgtccatccagccatctccacccacctcatctttgccctgggaaggagtccactgggtgactgtgaccatgaacgcctccctttggacaacaagcgactctgaccttgaaaggctctgccccacccatgtccttcactcctgccagagctttccttgggatggtttccaagggaaaggagagaaagatcaagaaaccaagacgaaaggctctgtgtgaagtcaaggaaagcagggccctaaaaaagggaaaaatcaatgtttacatgggatgccggaaacaaaggccagcctcgccctggctgactgcagggtgatgggaccagccctcccgttaggatctgaggtgctattcattctctccctggccctgcttaatctcagagccttctagtcatcgttggtttggaagagacccctctctataggaaggggtctaatcctcaagcccattgtcaggggctttttttttttttctttttggaagcaaaacgggcctcaggctggggatggttgggaggataccatagtgcagatgtctccttcccctctgtaaatagtatttttatacttcatcttcaccatcaccatctcaggctttacacgtgcagcccctcccccacccaggatggaggggggggctgtggagtgtccccttccttccctgaacagggcggctgagagtgggaaaaggttatgtatttaaagaaaattaaatttaataacatgtttctctaatcaaatttttggcttgtggttgtggcctgtgccaggagagggaacagagctctttacctgccttcccccagtcagaccatacttgaggtttctaatccttaacaaaacctgagggctggacatctatctcaacaatagagtgcttgggtaacatgctcaaggccctgggctcagtttttggaatggaaaaaaaaaaaaaaaaagtggggagggaggattaacttattgaacactggtataaaataagatctgatgaagccaggatcaatcgttggaagttttagaaacattgtaaagttgatttcaagcacagcattcactcaactgacttgaattctacctggtggttgattgtcagtgatctggcgacctcagaggcccatgtagctaccctggcaccccatctctttactaatcctgtgtcgctgacagtccctccctggcacatcctagcctcctacacacatctagaattccatgtggtagcaacaggtatgaccctgcgtgcatccagatcctccacccacagcctccagcttagctttgccagtttcccaaggggcctgctgtcaacagtgagtgcgatcagaatgggatggtgttgggaacacctttcttaagcataaggtaactagaccctggttggcccttgcttgggagcacaaatcgatgccagtcaagcaggcagcacgccttgggtgctgagctcaggaaagccatttgctgagcatggtttggattgatgtcagctgtgaaaaagctacccatcattgagtactagatacctggagtaggtatagtgctgtcttactcagccattgtcttatgcatcttggacaacaccaaggtgtaattgggtacctgactatgggctcttctacaggaaggtgcctttactctttacattaagtgacccctgcttgctattgtcaaccttaagagaaacagatctctctccactgggtcaccacttcctcttctagcagtgatagtctggaagtattgaggaattttgatgtattttctcagccgatttcagcctacccctcagttcctgctgcaggtggattcactggtggagaaagtaatcaggttggctttgtatctcccacctcatcatctctccttgcaactgggagggttcatcagtgttagcatcctgatgaaaatgttagcacgaaaaagcttgtttcacagctttcaaaacagtgttaccaggtcaaaatgatgtgggggcaggaaataccttttattccccgtgcttctattgaacctgggtggtatatattacagagtacacagaagggaaaatgatactggttagctgatcagctcaactggcagccgctaagcacaattagacactatgtccccaattcacacagtcacctgtgaagtcttgtgacttggttaagcctttttagaacacctgctgcctggtttggccacttgacaggcaaatcctgaccttggcgaaatggtgtgagcactgtgcttgggtggcaagctcacataatcgagatctttactcagctgtcttttcagcagcagcccgagtgtatattgccaagacatgatgctcaatcagcagcccgagtgtatgccaagacatgctcagtctagggagcagtaatgtggacattgactttgattaaccagactgtggggaccagagagttcaaaccattctgtatgaactgaggtgggaaagacagtaggttagaacataaagggaggaagtactgtgtggaagccaggaacaggattggatagagtaagcaccctgaactttatttacataaaacttaaaaaaaaaaacccactatgttccatctgagaactaagcaaattattctctcctctgggtcctatatatagccacaggcagctacaatagacctataactattcaaattagcaaagaatgtataccttgaatatatctgaaagggaaaaagatcaaaggaagttgtgttgtgaccagtacatgccagcttcagcaaagaagggtttttgttctttccccccaacagaagacatttttcttgcttctctgaatatactgaatttaggattagtttgtttaaaaaaaaatcggtgctcacataattagacactaagtgtcagctaactaacacaaccccaggcagtgtggatccaaggtcagtgtcactttccttgccccacagttttgaaagcagatggtgctaaagactctcaaagtaccaggtgctgtcaagcctggtgcagtctgggaagacaagcctcatcataggcctgtgagctgtaccctagccactgttaggaacagggcagggtcttggaatttatagtctgtgtttgattacttgtttaatttggtgtctcttgtgtttaattccacaatgaatgactttttaaaaaaagatttattatttatatgtatgtatactgtacctgtcttcagacacaccagtagagggtgtcagatgtcattatggatgattgtaagccaccatgtggttgctgggatttgaactcaggaccttcagaagaacagtcggtgctcttaacctcgctgagctatatctccagctcccaatgaatgacttaagtcttaaatagaaccaccatttaaaactgggtaaatgaagtgagacagagctcctctagggaaaaatttgaaattcagcgatagcttgggataatggtgataggtgaatttaaaagtgggctaccacattgggtcacacatgcttttaatcctgacacctgagaggcagaggcaagtggatctctgaatgtgaggccagcttggtctggtctacatagatagccagggttatggggagtggggggaggtgcggggagggggagaagtcacccttcctcttgatagttctactcaaccagcacttcccatgtgttcactagaatttttattccttagttctgtcaagattgtcccttatacatgcctaccctccattctatcacattgcccgtctctttgaacatcagagtaacatcctgccaggtcactggaagctcagacttctgttgaagcctcatccacaggttcggaggggcagatgtgattgagttggagacaagaactgttattatacaaattcatgggacatgacgccatttatcatcccacttaataagcattggattccaactgatccaatccaagaaaataaaaaccatgcccatttcccttctgatgggaagacatcaaatgtcacctttgtgttttgatccgttccttatgtgacagcttaacaagaaaccatcatgtgctctgtagaggaatagctagggggacatcagccaggagatatactggaagacacttttgatggcgactgagtgttctcagtcacgaccccccacaaagctcacttttcttcctcttttttcctccaattttcttcatctattcctattctctaacattactaagatgccatactattgaagaattttccagatgggctgtaggtaccatgaatggggctctgagttctaaatgttcagtaaataagcattgagtctcaagggggtgctgatatcctcaaagacatgaatatcatttgtgatgtctggaacattaaaggaacgatgtagcataaagaagccaataaaaaccagaagaaatctctactggaa

//